51 results about "Vitamin a acid" patented technology

A medicine for treating psoriasis vulgaris contains clobetasol propionate and vitamin A acid. Its preparing process is also disclosed. Its advantages are high curativ effect, and low toxic by-effect.

The invention provides skin protection cream capable of eliminating striae gravidarum. The skin protection cream is characterized by comprising, by weight, 10-15 parts of epidermal cell growth factors, 10-15 parts of kaempferol, 5-10 parts of methylsilanol hydroxyproline aspartate, 5-10 parts of vitamin A acid and 10-15 parts of collagen. The skin protection cream has the advantages that the striae gravidarum can be lightened and eliminated by the skin protection cream, and the treatment time can be shortened.

The invention relates to a compound external medicine for treating acne. It is characterized in that: the matrix carrier of the compound external drug contains the following two effective active ingredients (weight percentage): 0.01-2% of tazarotene, and 0.25-5% of antibacterial drugs; the effective active ingredient contained in the compound external drug After mixing with a base carrier, it forms a cream or gel or a liniment or film. The advantage of the present invention is that: the present invention contains two main components of retinoic acid and antibacterial for treating acne in the form of a compound preparation, so as to simultaneously exert three (and above) curative effects (dissolving horn plugs, regulating keratinization, Antimicrobial, anti-inflammation, secondary factors to reduce sebum secretion, etc.), played a complementary and synergistic effect in pharmacology.

The invention relates to application of effective component eucommia total glycoside in the medicament preparation for curing osteoporosis. The medicament for curing osteoporosis which is prepared from effective component eucommia total glycoside can be used in the form of soft capsules and hard capsules, wherein soft capsules are proportioned by one part by weight of eucommia total glycoside and 0.5-8 parts by weight of sea-buckthorn seed oil or edible vegetable oil or polyethylene glycol 400 and are prepared by applying conventional process for preparing soft capsules. Hard capsules are prepared by filling eucommia total glycoside into capsules. Proved by pharmacological test, eucommia total glycoside can not affect weight increasing of animals and no obvious effect is found on organ index. Eucommia total glycoside can obviously increase bone mineral density, greatly strengthen femoral fracture stress and femoral crushing stress, and increase bone length reduce which is caused by vitamin A acid and bone weight reduce. Eucommia total glycoside can not obviously affect serum estrogen level and has good function on osteoporosis of rats which is caused by vitamin A acid resistance.

The present invention relates to one kind of small segment double stranded RNA molecule (siRNA) with high efficiency interference on the expression of target gene Rig-G. The high efficiency siRNA is prepared through the following steps: 1. selecting site in the cDNA sequence of target gene to synthesize DNA template; 2. extracorporeal transcription to synthesize RNA segment; or constructing siRNA expression plasmid. Using these siRNA can inhibit the expression of Rig-G gene effectively and lay foundation for establishing Rig-G deficiency type cell strain mold, and is favorable to understanding the effect of Rig-G in vitamin A acid signal conduction network and revealing the molecular mechanism for vitamin A acid to induce APL cell differentiation.

The invention relates to a medicinal control release nanometer and method for making same, in particular a retinoic acid release control nanomicrosphere and its preparation method, the constituents of the composition are polylactic acid (PLA), vitamin A acid (RA) and gelatin aqueous solution.

The invention relates to a bangosome retinoic acid aerosol which can prevent chronic obstructive pulmonary. The ingredients of the aerosol include: retinoic acid bangosome, cefepime or ceftazidime, fluormone or cetacort and distilled water. The mentioned retinoic acid bangosome is made of the following materials: 1-2 share (by weight) retinoic acid, 10-15 shares (by weight) cholesterol, 10-15 shares (by weight) lecithin and 0.01-0.2 VE. The producing procedures go as follows: mix 2-3 shares (by weight) retinoic acid bangosome with 0.1-0.2 cefepime or ceftazidime, 0.0005-0.0025 fluormone or 0.01-0.05 cetacort; add distilled water to the ingredients at the ratio of 1:15-1:20; fill the material into clean jars to get the aerosol.

The invention relates to a medicine for treating acne and an application method thereof. The medicine comprises an internal adjustment preparation and an external application medicine, wherein the internal adjustment preparation comprises angelica, zinc sulfate, balloon flower and vitamin B; the external application medicine comprises a white medicine and a black medicine, wherein the white medicine comprises stearic acid, potassium hydroxide, glycerol, ethylparaben, water, vitamin A acid and metronidazole as effective ingredients; the black medicine comprises rhubarb, sulfur, almond, ginkgo and litharge as effective ingredients. The medicine comprising the internal adjustment preparation and the external application medicine, provided by the invention, is obvious in curative effect and convenient to use, has a beautifying effect and has market popularization values.

The invention discloses a culture medium for inducing mesenchymal stem cells to be differentiated into nerve cells. The culture medium comprises a basal culture medium and an inductive agent added in the basal culture medium, wherein the inductive agent is prepared from vitamin A acid, 2-mercaptoethanol and folic acid; in addition, in the culture medium for inducing the mesenchymal stem cells to be differentiated into the nerve cells, the concentration of the vitamin A acid is 10 to 50mu g / ml, the concentration of the 2-mercaptoethanol is 60 to 95mu g / ml, and the concentration of the folic acid is 65 to 75mu g / ml. According to the culture medium, the distortion and death number of cells in an inducing process can be effectively reduced, and higher surviving rate of the nerve cells formed by inducing is guaranteed.

The invention provides a kind of cream for treating psoriasis and its preparation method. It is supplemented with zedoary volatile oil and small dose of retinoic acid, and the two medicines are respectively packaged and treated with stearic acid by modern pharmacy method. , glyceryl monostearate, white petrolatum, liquid paraffin, glycerin, triethanolamine, sodium lauryl sulfate, ethylparaben, and distilled water to make an oil-in-water (O / W) compound cream. Compared with the prior art, the medicine of the present invention not only has high safety, good curative effect, no toxic side effect and low recurrence rate, but also has the advantages of stable property, controllable quality, low cost and the like.