98results about How to "Extensive treatment" patented technology

A small implantable stimulator(s) includes at least two electrodes for delivering electrical stimulation to surrounding tissue. The small stimulator provides means of stimulating a neoplasm with direct electrical current, such as relatively low-level direct current, without the need for external appliances during the stimulation session. The stimulator may be configured to be small enough to be implanted entirely within a neoplasm. Open- and closed-loop systems are disclosed.

An ultrasonic medical treatment device takes the form of an elongate probe having an elongate wave-generating concave surface with a longitudinal axis and ultrasonic electromechanical transducer elements for vibrating said concave surface to generate ultrasonic pressure waves focused along a linear locus extending parallel to said longitudinal axis. The probe may include a monolithic piezoelectric crystal element and electrode pairs provided along the unitary or monolithic element in a spaced array.

Provided are oral pharmaceutical compositions comprising sustained release or a combination of sustained and immediate release formulation of cannabinoids, a process for their preparation and methods of use thereof.

The present invention relates generally to the maintenance of blow flood using drug eluting stents and / or other coated medical devices to increased length of time of blood flow. Further, the present invention relates to drug-releasing coated devices for reducing smooth muscle cell proliferation and platelet activity to further limit restenosis utilizing resveratrol and quercetin, polyphenols that are linked to the cardioprotection of red wine consumption. The present invention also provides products and methods for treating or preventing atherosclerosis, stenosis, restenosis, smooth muscle cell proliferation, platelet cell activation and other clotting mechanisms, occlusive disease, or other abnormal lumenal cellular proliferation condition in a location within the body of a patient.

The device (10, 36, 38, 42, 68) applies a negative pressure to an endoluminal surface in the body of a patient to facilitate healing of a wound in the endoluminal surface. The device comprises a flexible porous element (14) with a peripheral outer face (32) for contact with the wound, the outer face being defined between opposite proximal and distal ends of the porous element. A suction tube (30) for being connected to a suction source externally of the patient's body is provided in fluid communication with the porous element to apply a negative pressure to the wound via the outer face (32) of the porous element (14) upon operation of the suction source. The porous element (14) has at least one through passageway (16) extending from its proximal end to its distal end for passage of bodily substances of the patient through the porous element. The device can also include a drainage tube (22) for collection and drainage of the bodily substances from the patient, wherein the drainage tube is received in the through passageway of the porous element. The device is particularly suitable for assisted healing of anastomotic wounds but its use is not limited thereto.

There are provided devices for applying negative pressure to a wound in an endoluminal surface of a patient to facilitate healing of the wound and methods for use of the devices. The device (69, 94, 134, 140, 156, 164) comprises a flexible porous element with an outer face defined between opposite proximal and distal ends of the porous element. A suction tube (30) for being connected to a suction source externally of the patient's body is in fluid communication with the porous element (14) to apply the negative pressure to the wound via the outer face of the porous element. In some embodiments, the porous element has a longtitudinal passageway (16) for passage of bodily substances of the patient along the lumen defining the endoluminal surface through the porous element. In such embodiments, the device may also have at least one absorbent element (70, 80) for absorbing the bodily substances and which is disposed forwardly or rearwardly of the porous element (14). Embodiments of the device may also include a drainage tube (22) for collection and drainage of bodily substances from the patient and which is received in the longtitudinal passageway (16) of the porous element. In other embodiments, the porous element can be in the form of a mat wrapped around a feeding or other insertion tube. The porous element of a device embodied by the invention may also include one or more irrigation channels (85, 86) for delivery of an irrigation fluid into or though, the porous element. The porous element and / or absorbent element(s) may be sponge(s).

A solid pharmaceutical dosage form comprises a substrate containing an active agent and a solid composition deposited onto areas of a surface of the substrate and containing an active agent.

A floating dispenser is provided for dispensing a solid, dissolvable water treatment chemical into ambient water. The dispenser includes a bucket having top and bottom ends, a top wall covering the top end, an opening for admitting ambient water into the bucket interior, and a floatation ring that keeps only the top end above water such that the interior is water filled when the dispenser floats. A basket is disposed in the interior of the bucket for carrying a solid, dissolvable water treatment chemical, such as calcium hypochlorite. The basket is buoyant and movable vertically toward the top wall of the bucket. The dispenser includes a refill indicator that indicates when most of a full load of said chemical has dissolved. The refill indicator includes a pair of tabs that are connected to the basket and slidably mounted in slots in the top wall. The tabs extend above the top wall when the buoyant basket floats upwardly, providing a visual indication of the need for a refill that can easily be seen from a side angle.

A process for producing building materials, such as asphalt, cement, concrete, mortar, or plaster board from liquid paint sludge containing water and paint solids produced from overspray in commercial paint booth operations. The preferred embodiment comprises adding the liquid paint sludge as the hydrating agent directly to the building material mix.

The instant disclosure relates to methods, systems, and apparatus for polishing wastewater (i.e. non-potable water) using filtration media. More particularly, the instant disclosure relates to wastewater polishing using a bed of mixed metal oxides under certain operating conditions to remove a plurality of contaminants from a wastewater stream.

The invention belongs to the field of dentistry plantation restoration, and concretely relates to an oral implantation digital pontic restoration abutment and a plantation method thereof. The oral implantation digital pontic restoration abutment comprises implants, restoration abutments, a pontic and a digital abutment, the implants are respectively arranged between two adjacent teeth in the oral gum, each of the implants is provided with one restoration abutment, the digital abutment used for a scanner to scan as a reference is docked to the restoration abutments when the scanner scans, the implants, the restoration abutments and the digital abutment are respectively provided with a through hole, and the implants, the restoration abutments and the digital abutment are connected through screws inserted to through holes; and adjacent restoration abutments are connected through the pontic made according to the scanning result of the scanner, and the digital abutment dismounted restoration abutments and the pontic are respectively fixedly connected with a false tooth. The oral implantation digital pontic restoration abutment solves a problem that implantation pontics of different manufacturers, models, specifications and systems cannot be restored in a unified manner, and well overcomes disadvantages of clinic restoration.

The present disclosure relates to pharmaceutical compositions useful for (and to a method of) treating autoimmune, respiratory and / or inflammatory diseases and conditions. The method involves administering to a subject in need thereof roflumilast N-oxide by inhalation. The present disclosure particularly relates to the treatment of asthma and chronic obstructive pulmonary disease (COPD) by administering roflumilast N-oxide by inhalation.

The invention is a Chinese medicine granular used for treating various dysmenorrheal. The Chinese medicine granular is made by the following raw medicine materials by weight proportion: 10 to 20 portions of salvia miltiorrhiza, 5 to 10 portions of angelica, 5 to 10 portions of Zhixiangfu, 5 to 10 portions of rhizome corydalis, 5 to 10 portions of cassia twig, 5 to 10 portions of szechuan lovage rhizome, 5 to 10 portions of safflower, 10 to 15 portions of radix paeoniae lactiflorae, 10 to 15 portions of red paeony root and 15 to 30 portions of motherwort herb. The raw medicine materials are taken according to the weight proportion, extracted, concentrated and crashed into powder to obtain the granular. The Chinese medicine granular used for treating various dysmenorrheal has the functions of regulating Qi, activating blood, warm dredging, removing blood stasis, regulating menstruation and alleviating pain. The Chinese medicine granular used for treating various dysmenorrheal can treat various dysmenorrheal caused by syndrome of static blood blocking in uterine vessel resulting from stagnation of Qi, blood stasis, stagnation of blood and coagulation of coldness. Symptoms are as follows: hypogastric pain or cold pain appears before, after or during menstruation and pain can be alleviated by warmness; engorgement of breast, scanty bleeding or bleeding difficulty with dark menses and blood coagulum appears, and pain can be alleviated after blood coagulum is removed; or coated tongue is white and thin; tongue proper is dark or has petechia; and pulse is slow or sunken.

The invention discloses an herbal health-preserving pedicure powder and a preparation method thereof. The powder is composed of the following ingredients, by weight: 10 to 20 parts of Chinese mugwort leaves, 10 to 20 parts of Chinese angelica roots, 10 to 30 parts of cassia twigs, 15 to 30 parts of buck grasses, 15 to 30 parts of spatholobus stems, 10 to 20 parts of safflowers, 10 to 15 parts of Sichuan lovage rhizomes, 15 to 30 parts of speranskia herbs, 20 to 30 parts of common cnidium fruits, 10 to 15 parts of dahurian angelica roots, 15 to 30 parts of eucommia barks, 10 to 20 parts of white peony roots, 15 to 30 parts of red sage roots, 15 to 20 parts of red peony roots, 15 to 30 parts of flavescent sophora roots, and 15 to 30 parts of astragalus roots. The method is simple in technology. The powder is a convenient and quick treatment, without toxic and side effects and with a low cost.

A floating dispenser is provided for dispensing a solid, dissolvable water treatment chemical into ambient water. The dispenser includes a bucket having top and bottom ends, a top wall covering the top end, an opening for admitting ambient water into the bucket interior, and a floatation ring that keeps only the top end above water such that the interior is water filled when the dispenser floats. A basket is disposed in the interior of the bucket for carrying a solid, dissolvable water treatment chemical, such as calcium hypochlorite. The basket is buoyant and movable vertically toward the top wall of the bucket. The dispenser includes a refill indicator that indicates when most of a full load of said chemical has dissolved. The refill indicator includes a pair of tabs that are connected to the basket and slidably mounted in slots in the top wall. The tabs extend above the top wall when the buoyant basket floats upwardly, providing a visual indication of the need for a refill that can easily be seen from a side angle.

An apparatus and method for improving the operation of sewer systems includes a first sewer pipe connected to a source of other water and a second smaller diameter sewer pipe passing through the first sewer pipe and connected to sources of sanitary effluent. The second sewer pipe can be attached to the interior surfaces of the first sewer line by a curable adhesive material using a removable inflatable bladder to hold the second sewer pipe in position until the adhesive has cured sufficiently. As an alternative, positioning walls or arms, integral with the second pipe, form positioning spaces filled with a slurry material to hold the second sewer pipe in position. The slurry will harden in place to form an integral unit with the second pipe and the positioning walls or arms.

The invention relates to a disease preventing and curing medicinal mouth-muffle and a medicinal composite. The disease preventing and curing medicinal mouth-muffle (1) comprises a mouth-muffle body (2), one surface of the mouth-muffle body (2) is provided with an insert pocket (3), and a powder bag (4) which packages the medicinal composite is placed in the insert pocket (3). The medicinal composite comprises the following Chinese herbs by weight: 2.2 percent of chrysanthemum and muskiness, 4.2 percent of cinnamon, good ginger, long pepper, radix aconite, frankincense, myrrh and clove, 5.0 percent of vermilion, 6.4 percent of asarum, eaglewood, croton, resina draconis, early plum flowers and rhizoma ligustici wallichii and 7.6 percent of tooth soap, arsenic sulphide and brain sand. The disease preventing and curing medicinal mouth-muffle internally carries the medicinal composite which plays a role during the mouth-muffle wearing process, thereby having disease prevention and cure and being simple and direct and also effective in treatment.

An apparatus and method for improving the operation of sewer systems includes a first set of sewer lines connected to a source of other water and a second set of sewer lines of smaller diameter than the first sewer lines connected to sources of sanitary effluent, the first and second sets of lines being separately connected to a sewerage treatment plant. The second set of sewer lines can be attached to the interior surfaces of the first set of sewer lines by an adhesive material and fasteners. A liner can be provided in the first sewer lines with the second sewer lines being positioned between an exterior surface of the liner and the interior surface of second sewer lines.

The invention relates to a mycophenolic acid-xenopus laevis glucagon like peptide-1 (XenGLP-1) conjugated peptide and application thereof. The preparation method comprises the following steps: performing structural modification on side chains of XenGLP-1, and introducing mycophenolic acid small-molecule derivatives with a high binding rate of serum protein, thereby obtaining the XenGLP-1 conjugated peptide with high hypoglycemic activity and long pharmacological action time. The XenGLP-1 conjugated peptide disclosed by the invention has the effect of obviously improving the biological activity, and has excellent effects of reducing blood glucose and losing weight for a long time.

The invention relates to antibacterial modified chitosan spray and a preparation method thereof. The preparation method of the antibacterial modified chitosan spray comprises the steps of preparing modified chitosan, preparing gardenia oil, preparing geniposide, preparing spirulina polysaccharide and spirulina polypeptide and preparing chitosan spray. The antibacterial modified chitosan spray is applied to treatment on male and female pruritus vulvae and fungal infection, bacterial infection, folliculitis and vaginitis, also can be used for treating bedsore and long-term skin inflammation, can be widely applied and has antibacterial ability more than 99% on staphylococcus aureus, escherichia coli, streptococcus, candida albicans, pseudomonas aeruginosa or other fungi.

The invention belongs to the field of pharmacy, and relates to a nano drug delivery system capable of delivering a genetic drug towards secondary hepatocyte in a targeted mode and application. The nano drug delivery system is the nano drug delivery system capable of delivering the genetic drug towards the secondary hepatocyte in the targeted mode established by adopting cationic liposome preparedby (2,3-dioleacyl-propyl)trimethyl ammoniumchloride and cholesterol as a vector, wrapping a therapeutic plasmid pVAX 1-therapeutic gene-apolipoprotein AI gene for expressing hepatocyte targeted protein apolipoprotein AI, and inserting a hepatocyte-targeted lipid material, distearoyl phosphoethanolamine-polyethylene glycol 34000-galactose. In vitro and in vivo evaluation experiments prove that thenano drug delivery system can target on hepatocyte to achieve efficient and lasting liver protection effect durably, safely, stably and efficiently, and improve the therapeutic index of the drug and reduce the toxic and side effect of the drug; and the nano drug delivery system has good application prospect.

A plasma device including a casing, a first electrode, a second electrode, a nozzle and a gas ejection port is provided. The casing has a first chamber. The first electrode is disposed within the first chamber and has a second chamber. The second electrode capable of rotating in relative to the casing has a third chamber connected with the second chamber. The second chamber and the third chamber are adapted for accommodating plasma formed between the first electrode and the second electrode. The nozzle and the gas ejection port are independently disposed at the bottom of the second electrode respectively, wherein the nozzle is configured to eject the plasma, and forms an included angle with or is spaced a distance apart from a rotating axis of the second electrode. The gas ejection port is configured to eject cold gas.

The invention relates to special compound feed for carassius auratus gibelio and a preparation method of the compound feed. The compound feed is prepared by the following raw materials by weight percentage: 20-25% of soybean meal, 15-20% of rapeseed meal, 10-15% of cottonseed meal, 5-10% of fish meal, 20-30% of wheat middling, 3-6% of fish oil, 5-15% of bran, 1% of microelement additive for fish, 0.3% of decavitamin for the fish and 0.7% of special Chinese herbal medicine feed additive for the carassius auratus gibelio. With the adoption of the special compound feed for the carassius auratus gibelio, economic benefits of carassius auratus gibelio culture can be improved obviously; the compound feed can significantly reduce the disease incidence during the carassius auratus gibelio culture, particularly the incidence of an explosive hemorrhagic disease; a survival rate is increased by 11-13%; growth of the carassius auratus gibelio is promoted; the quality of the carassius auratus gibelio can be improved; and the cost of the raw materials used in the compound feed, the production cost and the use cost are lower, so that cost saving is facilitated.

A method of temporarily elevating the eyebrow position and softening undesirable glabellar muscle activity to affect a more desirable appearance. In a broad aspect the invention comprises injecting small quantities of botulinum toxin (BTX) equivalent in activity to 0.001 to 1.0 Units of botulinum toxin A, dissolved in 10 to 50 microliters microdroplets of injectable saline carrier, and injected 0.5 to 1.0 millimeters below the skin surface to treat the septal and orbital orbicularis oculi muscles, on each side of a patient's face. In sufficient numbers, injected microdroplets of BTX are able to selectively weaken these muscles. This method preferably also includes using microdroplets of BTX to treat: a) the depressor supercilii muscle, on each side; b) the procerus muscle; c) the corrugator supercilii muscle, on each side; and d) the inferior limit of the frontalis muscle where it meets the superior aspect of the orbital portion of the orbicularis oculi muscle.

The invention relates to Lactobacillus plantarum P8 capable of regulating short-chain fatty acid and total bile acid metabolism in a human intestinal tract. The Lactobacillus plantarum P8 is separated from yoghourt made by hand by Inner Mongolia shepherds and is collected in the China General Microbiological Culture Collection Center of China Committee for Culture Collection of Microorganisms on November 18, 2011, with the collection number being CGMCC No.5468. The invention additionally discloses a detection method of the Lactobacillus plantarum P8.

There is described a fluid treatment system comprising an array of independent fluid treatment reactors. The reactors are arranged in a manner whereby a flow of fluid may be passed through the array in a substantially helical direction. The fluid treatment system is capable of treating large volumes of fluid (e.g., water) while requiring a relatively small foot print. In essence, the present fluid treatment system concentrates a relatively large number of radiation sources in a relatively small amount of space resulting in the ability to treat large volumes of fluid (e.g., water).

The invention relates to Chinese medicinal granules for treating various types of dysmenorrhea, which are mainly prepared from the following raw material medicaments in part by weight: 10 to 20 parts of root of red-rooted salvia, 5 to 10 parts of Chinese angelica, 5 to 10 parts of prepared nutgrass galingale rhizome, 5 to 10 parts of yanhusuo, 5 to 10 parts of cassia twig, 5 to 10 parts of szechuan lovage rhizome, 5 to 10 parts of saffron, 10 to 15 parts of white paeony root, 10 to 15 parts of red paeony root and 15 to 30 parts of motherwort herb. A preparation method comprises the following steps of: selecting the medicinal materials in proportion, extracting, concentrating, pulverizing and pelletizing to obtain the granules. The Chinese medicinal granules have the effects of regulating qi to invigorate blood circulation, warming and removing blood stasis and regulating menstruation and relieving pain, and mainly treat the following symptoms of various types of dysmenorrhea caused by uterine vessel stagnation due to qi stagnation and blood stasis and cold obstruction and blood stagnation: swelling pain or crymodynia of lower abdomen before and after menstruation or in menstrual period, and the pain is relieved under the warm condition; swelling in chest and hypochondrium and breasts; little menstrual blood volume or menstrual stagnation, dark menses with mass, and the pain is relieved after blood clots are removed; and thin and whitish coated tongue, dark tongue nature or petechia and wiry slow or deep pulse.

The invention relates to an Xenopus laevis GLP-1 analogue, a synthesis method and applications thereof. According to the present invention, the side chain and the C terminal of Xenopus laevis GLP-1 are subjected to structure modification to obtain the Xenopus laevis GLP-1 analogue with advantages of high blood glucose lowering activity and long pharmacological action time; and the Xenopus laevis GLP-1 analogue has significantly improved biological activity, and further has effects of strong long-acting blood glucose lowering and strong weight reducing.

The present invention discloses a organic germanium Ge-132 ganoderma lucidum drink, including 2% ganoderma lucidum concentrated solution, 2% grey polypore concentrated solution, 0.2% flavor moderator and 6 to 240mg organic germanium Ge-132 by the weight of per 100ml mineral water. The drink of present invention is scientific prepared according to the intrinsic property of organic germanium Ge-132, ganoderma lucidum and grey polypore etc to form a synthetical drink which integrates functionalization, nutrition, non-pollution, intelligent, liver protecting, scientific and so on, which has the functions of detoxication, liver protecting and enhancing human immunologic function, and which is nutritious health production having cancer prevention and cancer suppressive effects. Simultaneously the present invention also discloses a preparation method of organic germanium Ge-132 drink.