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Cream for treating psoriasis and its preparing process

A cream, a technology for psoriasis, which is applied in the pharmaceutical field of external medicines for treating psoriasis, and achieves the effects of improving differentiation, inhibiting keratinocyte proliferation, and having no toxic and side effects.

Inactive Publication Date: 2009-08-05
AFFILIATED HOSPITAL OF ZUNYI MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But, for the topical treatment of psoriasis, there are too few creams for external use that can be supplemented by traditional Chinese medicine as the main drug and western medicine for clinical use at present.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0013] Embodiment of the present invention: use turmeric oil 66ml, tretinoin 1.8g, stearic acid 153g, glyceryl monostearate 87g, white petrolatum 87g, liquid paraffin 166g, glycerin 126g, triethanolamine 3.1ml, lauryl Sodium sulfate 3g, ethylparaben 1.5g are made emulsifiable paste by following method.

[0014] Weigh 300-600g of zedoary medicinal material, crush it, pass through a No. 2 sieve, add distilled water whose weight is 7-8 times the weight of zedoary medicinal material, heat and reflux for 4-6 hours, until no volatile oil flows out, extract the distillate with ether, and collect zedoary oil 66ml; weigh β-cyclodextrin according to the ratio of volume to weight, that is, zedoary oil:β-cyclodextrin=1:2~1:3, and then according to the weight of β-cyclodextrin according to the ratio of 28~32ml / g Add distilled water, stir and mix β-cyclodextrin and distilled water thoroughly, heat to dissolve and let it cool to room temperature, then add zedoary oil, stir thoroughly for 3-4...

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Abstract

The invention provides a kind of cream for treating psoriasis and its preparation method. It is supplemented with zedoary volatile oil and small dose of retinoic acid, and the two medicines are respectively packaged and treated with stearic acid by modern pharmacy method. , glyceryl monostearate, white petrolatum, liquid paraffin, glycerin, triethanolamine, sodium lauryl sulfate, ethylparaben, and distilled water to make an oil-in-water (O / W) compound cream. Compared with the prior art, the medicine of the present invention not only has high safety, good curative effect, no toxic side effect and low recurrence rate, but also has the advantages of stable property, controllable quality, low cost and the like.

Description

Technical field: [0001] The invention relates to a cream for treating psoriasis and a preparation method thereof, belonging to the pharmaceutical technical field of externally used medicine for treating psoriasis. Background technique: [0002] Psoriasis is a stubborn, refractory chronic inflammatory skin disease with a high incidence rate, long course of disease, and easy recurrence, which seriously affects the physical and mental health of patients. It is one of the diseases that are currently focused on research and prevention. The pathogenesis is still not very clear, and there are no specific treatment methods and drugs. Currently, hormones, immunosuppressants, antineoplastic drug preparations and other chemical drugs are often used in clinical treatment, but their application is limited due to their high toxicity and side effects. Traditional Chinese medicine calls this disease "white diarrhoea" and "pine skin tinea". Compared with chemical drugs, traditional Chinese ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06A61K36/906A61K31/203A61P17/06
Inventor 田应彪陈泽慧匡菊香
Owner AFFILIATED HOSPITAL OF ZUNYI MEDICAL COLLEGE
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