The invention provides
Chimonanthus nitens leaf concentrated pills and a preparation method thereof. The preparation method comprises the following steps of: by taking
Chimonanthus nitens leaves as araw material; extracting
Chimonanthus nitens leaf volatile oil by virtue of a
microwave-assisted
steam distillation method; concentrating and
drying an
alcohol extract into an extract; concentrating and
drying a water extract into clear paste
powder;
drying dregs obtained by filtering;
grinding and then screening to obtain fine dreg
powder; forming pills from the fine dreg
powder, the extract andthe clear paste powder by virtue of a molding method; drying at a low temperature, thereby obtaining pills; preparing the volatile oil into a beta-
cyclodextrin inclusion compound; drying;
grinding into powder; covering the pills, the fine dreg powder, the
inclusion compound powder and a disintegrating agent;
rounding; and
polishing, thereby obtaining the concentrated pills. The Chimonanthus nitensleaf concentrated pills prepared by the invention are high in content of active ingredients of the
Chimonanthus nitens leaf, high in
bioavailability and high in active
titer. According to the preparation method disclosed by the invention, on the basis of a
traditional use manner of the
Chimonanthus nitens leaves, all components of the
Chimonanthus nitens leaves are used, so that the concentratedpills have the advantages of being high in medicinal material availability and capable of reducing resource waste, the administration compliance of patients can be improved, and the concentrated pillshave excellent market prospects.