56 results about "Chimonanthus" patented technology

The invention belongs to the technical field of essential oil extraction, and in particular relates to an extraction process for a Chimonanthus fragrans essential oil. Aiming at the characteristics of Chimonanthus fragrans, the extraction process employs the processes of collecting, transporting and storing, pretreating, pulverizing, microwave extracting, steam extracting and purifying in a proper order, thus improving the extraction rate of the Chimonanthus fragrans essential oil. The Chimonanthus fragrans essential oil is sampled and measured by gas phase chromatography to obtain that the organic solvent residue is zero. The extraction process provided by the invention can employ large-sized extraction equipment to carry out large-scale extraction of the Chimonanthus fragrans essential oil, can realize industrial production, and fills the blank of the extraction of the Chimonanthus fragrans essential oil at home and abroad.

The invention relates to a beverage, in particular to a chimonanthus beverage and a preparation method thereof. The chimonanthus beverage comprises the following components in percentage by mass: 10 to 30 percent of chimonanthus extract, 0.01 to 0.5 percent of chimonanthus essential oil, 0.01 to 1 percent of citric acid and 0.01 to 1 percent of sodium citrate. The method for making the chimonanthus into a beverage deepens the processing of the chimonanthus, and improves the economic benefit of a product; and the beverage keeps the original extract nature and flavor of the chimonanthus, has tasty and cool taste, has the functions of resisting bacteria, diminishing inflammation, resisting virus, enhancing the immunity of the body and the like, has no toxic or side effect, and is convenient to eat.

The invention relates to the field of traditional Chinese medicine preparation and relates to a preparation method of a chimonanthus inhibited acetylcholinesterase active part and application thereof. The preparation method comprises the following steps of: ethanol lixiviation, low-polarity solvent extraction, acid-solution and alkali-isolation chloroform extraction or alkali-solution and acid-isolation, centrifugation and ethyl acetate extraction. The extracted active part includes three categories of substances, namely alkaloids, flavonoids and coumarins respectively. The active part has relatively strong inhabitation effect on the activity of acetylcholinesterase and has a wide application range in preparing medicaments for preventing and treating related symptoms or diseases caused by acetylcholine deletion, particularly the medicaments for preventing and treating senile dementia.

The invention belongs to the field of medicines and health products, and concretely relates to an application of Chimonanthus salicifolius total alkaloid extract and monomer compounds thereof in the preparation of medicines or health products for treating gastrointestinal tumor diseases. The Chimonanthus salicifolius total alkaloid extract and chimonanthine monomer compounds (1-4) are extracted and prepared from a Calycanthaceae Chimonanthus plant Chimonanthus salicifolius, and experiments prove that the Chimonanthus salicifolius total alkaloid extract can substantially inhibit proliferation of stomach cancer SGC-7901, colorectal carcinoma SW1116 and colorectal carcinoma HCT116 cells and induce cancer cell apoptosis, and the alkaloid monomer compounds have different inhibition effects on the stomach cancer SGC-7901, colorectal carcinoma SW1116 and colorectal carcinoma HCT116 cells. The Chimonanthus salicifolius extract and the monomer compounds thereof can be applied individually or together or be combined with a suitable excipient, can be processed through a routine method to prepare an oral or non-oral dosage form used for treatment or assisted treatment of gastrointestinal tumor diseases, and is especially suitable for being used to prepare medicines or health products for treating stomach cancer and colorectal carcinoma.

The invention discloses a use of chimonanthus plant anti-mycobacterium tuberculosis, and particularly relates to application of a chimonanthus plant and an extractive thereof for preparing pharmaceutical for anti-mycobacterium tuberculosis and diseases caused by the anti-mycobacterium tuberculosis. The chimonanthus plant comprises willow-pattern calyx canthus, Zhejiang calyx canthus and mountain calyx canthus. The extractive comprises a water extractive, an alcohol extractive, a steam distillation extractive and a supercritical extractive.

The invention discloses food retention-removing and summer heat-relieving tea and a production method thereof, and relates to the technical field of health tea. The production method disclosed by the invention comprises the following steps: picking tea leaves, removing tea-green colour and withering, picking and treating chimonanthus nitens, treating ginger, treating brown sugar, uniformly mixing, rolling, fermenting, drying and extracting fragrance. According to the production method disclosed by the invention, nutritional ingredients in tea leaves, chimonanthus nitens, ginger and brown sugar are combined together by a scientific method, thus forming tea with food retention-removing and summer heat-relieving effects and with a high nutritional value.

The invention belongs to the technical field of medicines, and discloses application of a Miao-medicine radix chimonanthus extract in preparation of anti-AD (Alzheimer's Disease) products, and an AD treatment medicine prepared by ethyl acetate extract of Miao-medicine radix chimonanthus. A preparation method of the ethyl acetate extract of Miao-medicine radix chimonanthus comprises the following steps of cleaning the radix chimonanthus by water, removing impurities, airing, crushing, soaking the powder into 70% ethyl alcohol for 16h, extracting by 70% ethyl alcohol for 5h in a heat reflux way,filtering, concentrating by an extracting solution, extracting by ethyl acetate, respectively rotating and evaporating the extracting solution, reducing pressure and concentrating, and volatizing thesolvent in a water bath pot with temperature lower than 65 DEG C, so as to obtain the ethyl acetate extract. The extracting site of the ethyl acetate of the Miao-medicine radix chimonanthus has the anti-AD activity.

The invention discloses a Chimonanthus nitense leaf drop pills for preventing common cold and preparation process, wherein the drop piils comprises (by weight ratio) 1,8cineole 1-10 parts and flavonoid glycoside 1-10 parts extracted from Chimonanthus intense leaves, water-based or oil-based base material 7-150 parts, excipient 0.01-10 parts.

The invention discloses application of chimonanthus plant anti-helicobacter pylori, and particularly relates to chimonanthus plants and application of extracts of the chimonanthus plants in preparing drugs for preventing / treating related diseases caused by helicobacter pylori. The chimonanthus plants comprise chimonanthus salicifolius, chimonanthus zhejiangensis or chimonanthus nitens; the extracts comprise a water extract, an alcohol extract, a water vapor distillation extract and a supercritical extract.

The invention provides Chimonanthus nitens leaf concentrated pills and a preparation method thereof. The preparation method comprises the following steps of: by taking Chimonanthus nitens leaves as araw material; extracting Chimonanthus nitens leaf volatile oil by virtue of a microwave-assisted steam distillation method; concentrating and drying an alcohol extract into an extract; concentrating and drying a water extract into clear paste powder; drying dregs obtained by filtering; grinding and then screening to obtain fine dreg powder; forming pills from the fine dreg powder, the extract andthe clear paste powder by virtue of a molding method; drying at a low temperature, thereby obtaining pills; preparing the volatile oil into a beta-cyclodextrin inclusion compound; drying; grinding into powder; covering the pills, the fine dreg powder, the inclusion compound powder and a disintegrating agent; rounding; and polishing, thereby obtaining the concentrated pills. The Chimonanthus nitensleaf concentrated pills prepared by the invention are high in content of active ingredients of the Chimonanthus nitens leaf, high in bioavailability and high in active titer. According to the preparation method disclosed by the invention, on the basis of a traditional use manner of the Chimonanthus nitens leaves, all components of the Chimonanthus nitens leaves are used, so that the concentratedpills have the advantages of being high in medicinal material availability and capable of reducing resource waste, the administration compliance of patients can be improved, and the concentrated pillshave excellent market prospects.

The invention discloses a Chinese medicinal preparation for relieving cough and eliminating phlegm, having reliable curative effect, pure taste, no obvious toxicity and side effect, rich sources of medicinal materials and low price, and its preparing method, prepared of Chimonanthus flower 13-20 shares, xianzhuli 35-50 shares, dried tangerine peel 10-15 shares, and liquorice 15-25 shares; and its preparing method: 1. adopting steam decompression distillation method to extract naphtha from Chimonanthus flower and dried tangerine peel; 2. adding liquorice to the medicinal material after extracted to decoct in water for 3 times; 3. combining the filtrate, heating and concentrating; 4. adding xianzhuli, candy and sodium benzoate to the concentrate, and then adding in the naphtha extracted in step 1; 5. adding in water and blending uniformly, filtering, pouring, and sterilizing, and the invention can be widely applied to diminish inflammation, relieve cough, removing phlegm, and cure the symptoms such as bronchitis.

The invention provides acne and scar removal gel and a method for preparing the same, and belongs to the field of beauty and skin care products. The acne and scar removal gel comprises, by weight, 0.5-5% of Chinese herbal medicine extract, 0.5-2% of carbomer, 90-97% of water, 0.3-1% of glycerin, 0.3-1.5% of triethanolamine and 0.1-0.3% of auxiliary components. The Chinese herbal medicine extract is made of, by weight, 30-100 parts of rhizoma dioscoreae, 30-100 parts of fructus aurantii, 3-30 parts of radix ginseng, 20-80 parts of radix salviae miltiorrhizae, 10-80 parts of flos lonicerae, 10-80 parts of herba taraxaci, 2-10 parts of radix chimonanthus, 1-10 parts of semen clausenae, 1-10 parts of semen melo, 1-7 parts of daghestan sweetclover herb, 1-5 parts of smilacina japonica, 1-6 parts of semen firmianae and 1-5 parts of nux prinsepiae. The acne and scar removal gel and the method have the advantages that obvious acne removal effects can be realized by the acne and scar removal gel, the acne and scar removal gel is short in cure cycle and free of recurrence and further has scar removal and anti-allergic functions, good effects of inhibiting propionibacterium acnes can be realized, and obvious curative effects can be realized by the acne and scar removal gel for severe pimple patients.

The invention discloses application of a chimonanthus plant in influenza virus resistance, and particularly relates to application of the chimonanthus plant and extracts thereof in preparation of medicines for resisting influenza virus and diseases caused by the influenza virus. The chimonanthus plant comprises chimonanthus salicifolius, Zhejiang wintersweet and chimonanthus nitens; and the extracts are extracted by water extraction, alcohol extraction, vapor distillation and supercritical extraction.

The invention provides a preparation method of Chinese medicinal oral liquid made of Chimonanthus nitens leaf for treating common cold. The preparation method comprises the following steps of: soaking sun-dried Chimonanthus nitens leaf in water, extracting by steam distillation to obtain volatile oil, and filtering to obtain medicinal liquid and residue; decocting the residue in water twice, and filtering to obtain medicinal liquid; mixing the medicinal liquids, concentrating into fluid extract; cooling, adding ethanol, stirring, standing, filtering, recovering ethanol, and concentrating to obtain fluid extract; and mixing the fluid extracts with the volatile oil, adding corrective, antiseptic, essence and water, mixing, refrigerating, filtering, bottling, and sterilizing. The inventive oral liquid has the advantages of high degree of dispersion, good stability, controllable quality, and good safety.

The invention discloses a granule preparation capable of nourishing and protecting liver. A preparation method of the granule preparation comprises the following steps: weighing and preparing traditional Chinese medicine materials including flos chrysanthemi, plantain herb, folium mori, fructus lycii, flower of kudzuvine, red bean flowers, turnip seeds, radix puerariae, concha ostreae, fructus citri sarcodactylis, seville orange flowers, chimonanthus fragrans, flos albizziae, rhizoma gastrodiae, branchlet of sharpleaf gambirplant and rhizoma acori graminei, then adding a proper amount of water, heating and extracting, removing residues and extracting juice, concentrating and granulating to prepare the granule preparation. The granule preparation is special in formula and obvious in effect, is natural without toxic and / or side effects, and plays a more obvious healthcare function on people with hypoimmunity and liver function injury.

The invention discloses a medicine for treating lumbar disc herniation with syndrome of blood stasis and a preparation method of the medicine, wherein the medicine consists of the following medicinal raw materials: heterophyllous eupatorium herb, lycopodium clavatum, beautiful spotflower herb, lamiophlomis rotate, hedera helix, herba pyrolae, amber, herba lycopi, motherwort, ground beetles, nude fern herb, radix achyranthis bidentatae, tall monkshood root, herba scutellariae barbatae, fruticose breynia juvenile, herba salviae chinensis, cattail pollen, cortex moutan radicis, radix zanthoxyli, orpiment, lysimachia capillipes hemsl, phaseolus calcaratus, flos citri sarcodactyli, camphor root, radix chimonanthus, lindernia ruellioides, fructus piperis longi, rhizoma homalomenae, angelica sinensis, folium et cacumen murryvae and borneol. The medicine disclosed by the invention has functions of promoting blood circulation and removing stasis, regulating qi and relieving pain, and the medicine is mainly used for treating the symptom of blood stasis due to lumbar disc herniation. On the basis of the theory of traditional Chinese medicine, the medicine, from a holistic view, takes effects of improving a relation between protrusion and nerves, relaxing muscles in waist and back, recovering the normal alignment of lumbar vertebra, relieving pain, improving fibrous cartilage and the like by regulating blood circulation in whole body and by promoting blood circulation and removing stasis; and the medicine is safe and effective, convenient in administration, easy to be accepted in patients and applicable to clinical market development.

The invention relates to a traditional Chinese medicine wine for treating lumbar spondylosis, cervical spondylosis, early osteoproliferation and old wounds. The traditional Chinese medicine wine comprises the following raw material traditional Chinese medicines: flos carthami, periploca forrestii schltr, radix chimonanthus, radix aconiti agrestis, rhizoma chuanxiong, caulis polygoni multiflori, fissistigma polyanthum, rhizoma drynariae, alangium platanifolium and the like; a preparation method of the traditional Chinese medicine comprises the following steps of: after raw material traditional Chinese medicines are weighed, adding 50-55% of pure grain alcohol into the raw materials, completely soaking for three times, once a month, so as to obtain three parts of liquid medicine solutions; and finally evenly mixing the three parts of liquid medicine solutions, and split charging to obtain the traditional Chinese medicine wine. According to the invention, the traditional Chinese medicine wine for oral administration can be used for effectively treating the lumbar spondylosis, the cervical spondylosis, the early osteoproliferation and the old wounds, thereby being good for alleviating meridian impassability and hip joint pain of early femoral head necrosis; furthermore, the traditional Chinese medicine wine for oral administration and external use can be utilized to treat sprain; and the traditional Chinese medicine wine drunk in a small amount everyday can eliminate diseases and alleviate fatigue, so that the traditional Chinese medicine wine is good for dredging the channels, and is applied to physical trainers, sports exercisers and manual workers for use.

The invention discloses an application of chimonanthus plant extracts in preparing medicines, and in particular relates to an application of chimonanthus plants and extracts thereof in preparing medicines for preventing / treating various diseases. The chimonanthus plants include chimonanthus salicifolius, chimonanthus zhejiangensis or chimonanthus nitens; and the extracts are obtained by aqueous extraction, alcohol extraction, steam distillation and supercritical extraction.

The invention discloses a medicine for treating pulmonary fibrosis and a preparation method thereof. The medicine is mainly prepared from rhizoma phragmitis, radix asparagi, cortex llicis rotundae, wild groundnut seed, pratia nummularia herb, radix stellariae, radix chimonanthus, mirabilis jalapa leaf, radix astragali, radix ophiopogonis, human placenta, cordyceps sinensis, radix stemonae, rhizomacynanchi stauntonii, radix asteris, radix adenophorae, fructus schisandrae sphenanthera, flos farfarae, balloon flower, radix panacis quinquefolii, rhizoma atractylodis, radix pseudostellariae, driedlily bulb, lotus plumule, rhizoma anemones altaicae, Taiwan beautyberry leaf, herba androsace umbellate, gecko, aizoon stonecrop herb, radix kadsurea coccineae and root or all-grass of wahlenbergia marginata according to certain weight ratio. The medicine disclosed by the invention has the functions of nourishing yin and moistening dryness, clearing lung and reducing internal heat, tonifying liver and kidney, moistening lung to arrest cough, reinforcing deficiency and tonifying lung and invigorating spleen, and realizes a fast and good treatment effect when used for treating pulmonary fibrosis.

The invention relates to a chimonanthus nitens breeding method, which comprises a seed propagation method and a cutting propagation method. The seed propagation method includes steps of seed collection, seeding and management. The cutting propagation method includes steps of cutting selection, cutting bed preparation, scion collection and cuttage, rooting and management. By adoption of the seed propagation method, seed storage cost is saved, and the seed germination rate is increased; by adoption of the cutting propagation method, the technical problem of rapid propagation of chimonanthus nitens is solved, an effective approach is created for rapid and efficient propagation of chimonanthus nitens, and technical support is provided for large-scale production. By application of the seed propagation method and the cutting propagation method, wild resources of chimonanthus nitens can be protected effectively while production material demands of enterprises are met, and accordingly sustainable utilization is realized.

The invention discloses application of a chimonanthus plant in influenza virus resistance, and particularly relates to application of the chimonanthus plant and extracts thereof in preparation of medicines for resisting influenza virus and diseases caused by the influenza virus. The chimonanthus plant comprises chimonanthus salicifolius, Zhejiang wintersweet and chimonanthus nitens; and the extracts are extracted by water extraction, alcohol extraction, vapor distillation and supercritical extraction.

The invention discloses a Huaji heat-relieving tea and a preparation method thereof, and relates to the technical field of health-care tea. The invention comprises the following steps: picking tea leaves, withering green tea greens, picking and processing wintersweet, processing ginger, processing brown sugar, mixing, kneading, fermenting and drying to improve fragrance. The scientific method adopted in the invention combines the nutritional components in the tea leaves, wintersweet, ginger and brown sugar to form the tea with the effect of reducing accumulation and relieving summer heat, and has high nutritional value.

The invention discloses traditional Chinese medicine for treating chronic hypertrophic laryngitis and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine for treating chronic hypertrophic laryngitis is prepared from traditional Chinese medicine raw materials in parts by weight as follows: 5-15 parts of spreading hedyotis herbs, 3-12 parts of rhizoma belamcandae, 2-8 parts of radix glycyrrhizae, 6-10 parts of radix scutellariae, 3-7 parts of American ginseng, 3-7 parts of ciliatenerve knotweed roots, 2-10 parts of reed rhizome, 1-5 parts of rhizoma atractylodis, 4-13 parts of folium ginkgo, 2-8 parts of radix platycodonis, 4-10 parts of cortex eucommiae, 1-5 parts of radix semiaquilegiae, 4-9 parts of radix chimonanthus and 5-10 parts of purslane speedwell herbs. All raw materials contained in the traditional Chinese medicine for treating chronic hypertrophic laryngitis have a synergistic effect, and the traditional Chinese medicine for treating chronic hypertrophic laryngitis has a good treatment effect on laryngitis, takes effect rapidly and is low in recurrence rate and applicable to clinical popularization and application.

The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicinal capsule for treating lymphoma and a preparation method of the traditional Chinese medicinal capsule. The traditional Chinese medicinal capsule is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 35-40 parts of glaucescent fissistigma roots, 35-40 parts of radix chimonanthus, 20-25 parts of spreading hedyotis herb, 10-15 parts of airpotato yam rhizome, 10-15 parts of radix achyranthis bidentatae, 10-15 parts of fructus psoraleae, 8-10 parts of radix scrophulariae, 10-15 parts of fructus forsythiae, 8-10 parts of radix puerariae, 10-15 parts of radix trichosanthis, 8-10 parts of spica prunellae, 8-10 parts of radix ranunculi ternati, 10-15 parts of manyleaf paris rhizome, 6-8 parts of radix scutellariae, 8-10 parts of radix paeoniae rubra, 10-15 parts of fructus gardeniae, 6-8 parts of radix sophorae subprostratae, 10-15 parts of liquorice roots, 4-6 parts of concha ostreae and 8-10 parts of radix bupleuri. Since the traditional Chinese medicines have functions of clearing away heat and toxic materials, regulating qi circulation and eliminating stagnation, promoting blood circulation and removing stasis, the traditional Chinese medicinal capsule disclosed by the invention, has a significant curative effect in treating the lymphoma, and is rapid to take effect, and the traditional Chinese medicinal capsule is capable of boosting human immunity and inhibiting the generation and spread of cancer cells; in addition, the traditional Chinese medicinal capsule can take effects in resisting bacteria and diminishing inflammation, draining pus and expelling toxin, eliminating stagnation and relieving swelling; and the traditional Chinese medicinal capsule is easily available in medicinal raw materials, low in cost, high in cure rate, free from recurrence after curing, safe and reliable and is worthy of clinical wide popularization and application.

The invention relates to a flavonoid and monoterpenoid compound and its preparation method and application. Its structural formula is as follows: the compound is isolated from Chimonanthus gramatus M.C.Liu. In vitro biological activity experiments show that the compound has strong 1,1-diphenyl-2-picrylhydrazine free radical (DPPH) scavenging ability, and is a candidate compound of natural antioxidant and free radical scavenger.

The invention relates to a traditional Chinese medicine for treating the respiratory disease of a chicken, and falls within the technical field of veterinary medicines. The traditional Chinese medicine comprises the following raw medicinal materials: 280-320g of rhizoma cyperi, 280-320g of rhizoma zingiberis, 150-250g of rhizoma coptidis, 120-180g of radix platycodi, 80-120g of radix sophorae tonkinensis, 80-120g of radix glycyrrhizae, 40-60g of alum, 30-50g of Chinese honeylocust, 30-50g of calculus bovis artifactus, 25-35g of venenum bufonis, 25-35g of realgar, 50-70g of white spirit, 15-25g of flos inulae, 15-25g of phoenix tree flower, 15-25g of cortex mori, 15-25g of radix chimonanthus, 15-25g of radix folium et fructus litseae auriculatae, 15-25g of climbing groundsel herb, 15-25g of root of Japanese orixa, and 15-25g of borneol. The traditional Chinese medicine has good effects of clearing away heat, removing toxicity, remaining antibacterial, killing insects, reducing fire, relieving sore throat, diminishing swelling, relieving pain, preventing malaria, invigorating the circulation of blood, invigorating meridians, inducing resuscitation, relieving cough and asthma, and promoting appetite, the efficacy of the medicine can be directly applied to a wounded part, and the effects of quickly sterilizing, relieving swelling and pain, inducing resuscitation and invigorating meridians are achieved, so that the respiratory disease of the chicken is quickly cured.

The invention relates to the field of plant molecular biology, in particular to a chimonanthus praecox CpFPA gene, and an encoded protein and application thereof. According to the chimonanthus praecoxCpFPA obtained by cloning, the maximum open read frame (ORF, open read frame) of a cDNA sequence is 3099bp, and 1032 amino acids are encoded. Arabidopsis thaliana inflorescence is dip-dyed with pCAMBIA1300-CpFPA, it is found that compared with wild type arabidopsis thaliana (Col-0), transgenic arabidopsis thaliana has the advantages that the expression quantity of AtFLC and AtSVP is remarkably reduced, the expression quantity of AtAP1 and AtLFY is increased, and the scape time, bud appearing time, first flowering time, and first capsule forming time of transgenic arabidopsis thaliana strainsare all earlier than those of Col-0, rosettes are reduced, stem leaves are increased, and early blossoming phenotypes are presented. The result shows that the CpFPA gene can inhibit the expression ofAtFLC so as to promote the early blossoming of plants.