198 results about "Organic Synthesis Methods" patented technology

The present invention relates to nanoparticles comprising a biodegradable polymer, preferably the vinyl methyl ether and maleic anhydride (PVM/MA) copolymer, and a polyethylene glycol or derivatives thereof. These nanoparticles are easy to produce and provide excellent bioadhesion, size and zeta potential characteristics making them suitable for the administration of active molecules. The selection of the type of polyethylene glycol used in their production allows suitably modulating the characteristics of these nanoparticles, which can be advantageously used according to the type of drug to be carried and/or the method of administration of the pharmaceutical formulation. pegylation is carried out by simple incubation for a short time period of the two macromolecules in question, without needing to have to resort to the use of organic solvents with high toxicity or long and laborious organic synthesis processes. Furthermore, the pegylation process can be associated to the process of encapsulating the biologically active molecule.

The invention belongs to the field of nonlinear optical materials, and particularly discloses a hydrogel-based solid-state up-conversion luminescence material and a preparation method thereof.The material can be directly used in atmospheric environment and has quite high stability.The method includes: under excitation of low-power-density green light (532 nm, 60 mW.cm-2), enabling up-conversion hydrogel on a PdTPP/DPA system to obtain blue up-conversion luminescence.When temperature is increased, up-conversion efficiency (phiUC)of the material is in positive correlation with temperature and is up to 12%.A convenient and quick idea is provided for preparing up-conversion luminescence materials, and deoxidization is not needed, so that instability in organic solvents, complexity of organic synthesis methods and unfavorable effect on ecological environment protection are avoided usually, and actual application value is increased greatly.The material has potential application value in photoelectrochemical hydrogen generation and in the fields of solar photovoltaic field, solar photocatalysis, environment photochemical technology and temperature sensors.

The invention discloses an oxidizability and reducibility conducting polymer flow anode with used for a flow battery. An oxidizability and reducibility conducting polymer or a conducting polymer and an inorganic substance composite material are dispersed in electrolyte solution to form electrolyte of the flow battery, the electrolyte and a three-dimensional mesh current-collection body commonly constitute an emulsus flow electroactive polymer anode, and anode flow passes an anode chamber in a flowing form in the charging and discharging processes and is used for forming a flow battery system. As the dimension of the conducting polymer and the dimension of the inorganic substance composite material of the conducting polymer are large, the battery can adopt a common porous diaphragm; in addition, the corrosion of a medium system of the electrolyte of the battery used for an electroactive material to a solid current collector is small, and therefore, the environmental pollution is small in the production and using processes; the conducting polymer is rich in source, so as to be prepared on a large scale by an organic synthesis method; and the cost of the flow battery can be greatly lowered.

The invention discloses a method for preparing zaltoprofen. The method, which is simple in operation route, environmentally-friendly and suitable for industrial mass production, can realize industrialization. The zaltoprofen is a non-steroid anti-inflammatory medicament having effects of relieving inflammation, pain and heat.

The invention discloses a preparation method of core-shell graphene quantum dot @ mesoporous silica nano-material. The material employs graphene quantum dots as a core and hollow mesoporous silica asa shell, the diameter of nanometer particle is 80-120nm, and fluorescence emission wavelength is 570-670nm. The GQDs prepared by an organic synthesis method are used as a core, hMSN is used as a shellfor preparing GQDs@hMSN. The water soluble GQDs prepared by an organic phase synthesis method, GQDs is directly used as a core, in order to prepare the graphene quantum dot @ mesoporous silica nanometer particles, and after chemical etching, a compound with GQDs optical performance, a hMSN hollow meso-structure and abundant surface charges is prepared. The material has excellent optical properties and a hollow meso-structure, and the material can be applied to optical imaging and medical treatment in organism or diagnosis and treatment of tumor.

The invention belongs to the technical field of luminescent macromolecular composite material, and particularly relates to a method for preparing a sulfhydryl functional rare earth-macromolecular composite luminescent material. In the method, firstly, by adopting an organic synthesis method, aromatic organic micro molecules are grafted in an inorganic silica skeleton to obtain organic bridge precursor; the organic bridge precursor, polymers and rare earth ions are further combined to obtain the rare earth macromolecular material by chemical action; at last, by the sol-gel method, all obtained materials are subjected to polyreaction to obtain dried gel, so that the organic macromolecular polymers with long carbon chains are embedded in silica network substrate by covalent bond; and the dried gel is subjected to dry ageing to obtain the macromolecular composite material with stable chemical and thermodynamic performances, smooth surface appearance and special luminescence emission. The method has the advantages of simple preparation process, mild experimental conditions, strong operability, good reproductivity, low cost, stable quality of obtained products and order appearance, and the sizes of crystal grains can be controlled in the range of micron and nanometer.

The invention belongs to the technical field of an organic synthesis method, and particularly relates to a method for asymmetrically synthesizing a chiral quaternary carbon compound containing trifluoromethyl. The method comprises the following step: reacting trifluoromethyl nitroolefin with a 2-acetylaza aromatic compound to asymmetrically synthesize (R)-3- trifluoromethyl-3-nitryl methyl-1-(aza aromatic ring-2-yl)-butyl-1-acetone under the catalysis of bisoxazoline chiral ligand and a nickel catalyst in an organic solvent by adopting asymmetrically catalytic Michael addition reaction. The method is high in reaction yield and high in optical purity. The method disclosed by the invention can be used for a preparation tool for providing a trifluoromethyl quaternary carbon chiral compound.

The invention discloses a supermolecule heterojunction organic photocatalyst and a preparation method and an application method thereof. The photocatalyst is a BiOCl/PDI photocatalyst. Sheet shape BiOCl is prepared by a hydrothermal method; and perylene diimide (PDI) is synthesized by an organic synthesis method. BiOCl and PDI are taken as the raw materials to synthesize the BiOCl/PDI photocatalyst, or BiOCl and acidified PDI are taken as the raw materials to synthesize the BiOCl/PDI photocatalyst. The invention also provides an application method of using the photocatalyst to degrade organicmicro-pollutant wastewater. The preparation technology of the prepared BiOCl/PDI supermolecule photocatalyst is simple; the output is large; organic micro-pollutants in water can be efficiently degraded under a photocatalytic condition and a neutral condition without adding any oxidant; and the photocatalytic effect on cation type pollutants is better.

The invention relates to a chiral allyl ester compound and a preparation method thereof. The structural formula of the chiral allyl ester compound is represented in the description. The preparation method comprises the following steps: adding raw materials (carboxylate and allyl halide) into an organic solvent, then adding an iridium catalyst, which is prepared by reacting an iridium complex with a ligand, adding additives, controlling the reaction temperature in a range of 0 to 120 DEG C, carrying out reactions for 1 to 36 hours, and separating the reaction products so as to obtain the chiral allyl ester compound. In the prior art, when active allyl halide is taken as the substrate, the reaction yield is low and the enantioselectivity is bad, and the provided preparation method overcomes the problems mentioned above. Moreover the preparation method has the characteristics of high reaction yield, good region-selectivity, and high enantioselectivity, and thus is widely used in the organic synthesis methodology and natural product synthesis.

The invention relates to stable isotope labeled sudan red I and its synthesis method. The invention makes use of an organic synthesis method which comprises: employing stable isotope labeled benzene as a raw material, conducting nitration reaction so as to generate stable isotope labeled nitrobenzene, which then reacts with a reducing agent so as to obtain stable isotope labeled aniline, which is then subjected to diazotization as well as coupling with naphthol, thus obtaining stable isotope labeled sudan red I. Compared with prior art, the stable isotope labeled sudan red I prepared by the invention has chemical purity up to more than 98% and isotopic abundance over 98% after separation and purification, thus fully satisfying the demand for prohibited dye detection in the food safety field.