The invention belongs to the technical field of cosmetics, and in particular relates to an advanced moisturizing lotion and a preparation method of the advanced moisturizing lotion. The advanced moisturizing lotion is prepared from water, polyglycerol-10, glycerol, sodium chloride, hydroxyethylurea, lubrajel oil, diphenyl polydimethylsiloxane, diphenyl siloxy phenyl polytrimethyl siloxane, moisturizing factors, plant extract, gellan gum, monosodium citrate, xanthan gum, sodium hyaluronate, citric acid, methylparaben, phenoxyethanol and essence. The advanced moisturizing lotion can effectively moisten the skin, is obvious in moisture-preserving and water-locking effects, and enables the skin to be tender and moist for a long time.