76results about How to "Reduced dosing time" patented technology

It is an object of the present invention to provide an enzyme preparation which is excellent in stability in blood (blood residence) and in transfer to a target organ (targeting property), and can be used effectively in enzyme replacement therapy or the like.This problem is solved by a lipid vesicle composition wherein vesicles composed of a lipid bilayer membrane are encapsulating an enzyme, the composition being capable of retaining stably the activity of the enzyme even outside the stable pH range of the enzyme.

The invention relates to a preparation method of high viscosity cationic starch, which comprises the technological steps of: 1) using the mixture of an alkaline catalyst and an inhibitor to adjust the pH of starch slurry to be 10swung dash12; 2) heating and adding the mixture of an alkaline activating agent and a cationic etherifying agent, and stopping heating until the temperature reaches 40 DEG C; 3) using the mixture of the alkaline catalyst and the inhibitor to adjust the pH of the starch slurry to be 11swung dash12, keeping heating until the temperature of the starch slurry reaches 49swung dash50 DEG C, and etherifying for 1swung dash5h; 4) adding an alkaline cross-linking agent, and reacting for 1swung dash6h; and 5) dehydrating the starch slurry, obtaining green starch, adding an acidulant, mixing uniformly, acidizing the starch for 0.5swung dash2h at 50swung dash100 DEG C, and after cooling, smashing and screening, obtaining a product. The product has high paste viscosity, high acid and alkaline-resistant stabilities, and can be applied in the fields of paper making, mineral separation, oil fields, adhesives, waste water treatment and the like.

The invention relates to sterilized magnesium sulfate wet dressing agent. It is formed by medical using magnesium sulfate aqueous solution and carrier. The former accounts for 20-50wt%, and can be made by high temperature sterilizing after sand stick filtering with 0.50-0.80mum aperture. The latter can be the water absorption paper towel, gauze, or medical using dressing. It can be used to cure local subcutaneous tissue swelling ache. The using method includes the following steps: dressing it along the vein direction, changing for every 30-60min until to the dripping off, stopping the wet dressing after withdrawing the needle for 1-2h. The user can understand clearly through the direction for use on the packaging bag which can solve the problems of carryover, using inconvenient, and infection.

The invention discloses an MBR plate-type membrane cleaning agent, which comprises an alkaline cleaning agent and / or an acidic cleaning agent, and can efficiently remove various pollutants remained onthe surface and in the membrane pores of an ultrafiltration membrane. The invention also provides an MBR plate-type membrane cleaning method, wherein the cleaning agent is beaten into a plate-type membrane in a cross-flow circulation manner, standing aerating scrubbing is performed, and the residual cleaning agent in the membrane is recovered, so that the defects that the chemical cleaning of theexisting plate-type membrane is non-uniform and the agent cannot be recovered can be overcome, and the chemical cleaning strength and the membrane performance recovery rate after chemical cleaning are effectively improved so as to prolong the chemical cleaning period and the service life of the MBR plate-type membrane system.

The invention relates to a preparation method of a multifunctional slick water fracturing fluid drag reducer. The preparation method comprises the following steps: applying inverse emulsion polymerization reaction for compounding two non-ionic emulsifiers into a compound emulsifier, dissolving the compound emulsifier in an oily medium in the mass fraction of 0.3%, stirring for 1-2 hours under the protection of nitrogen, then adding 0.3% by mass fraction of a hydrophobic monomer, then adding 0.3-0.5% by mass fraction of a chelating agent and monomer solution of acrylamide and 2-acrylamide-2-methylpropanesulfonic acid, starting to heat, and after temperature is increased to 52-57 DEG C, adding an oil soluble initiator and a water soluble initiator in batches, and carrying out heat preservation for 8-10 hours after the initiator is completely added, so that stable water-in-oil type polymer emulsion is obtained finally. According to the invention, an inverse emulsion polymerization method is utilized, and by introducing special functional group substances and emulsifiers, a slick water drag reducer with anti-drag and discharge assisting functions is developed, slick water cost is reduced, more importantly, fluid preparation time is shortened, a fluid preparation procedure is simplified, and construction efficiency is greatly improved.

The invention relates to surfactant for displacing the oil of an offshore oilfield and a preparation method thereof, and the surfactant and the preparation method thereof belong to the technical field of surfactants. The surfactant for displacing the oil of the offshore oilfield comprises the following components: hydroxypropyl sulfo betaine type amphoteric surfactant is adopted as the main agent and alkylphenol polyoxyethylene ether non-ionic surfactant serves as the auxiliary agent. The preparation method comprises the following steps that 1) the main agent is prepared: (1) water is adopted as the solvent to react with sodium hydrogen sulfite, sodium sulfite and epoxy chloropropane, and 3-chloro-2-hydroxypropyl sodium sulfonate is prepared; (2) low-carbon alcohol is adopted as the solvent, the product in the step (1) and emulsifier are dissolved, 12 / 14 tertiary amine is dripped in, and reflux reaction is carried out; (3) the tertiary amine and the solvent which do not react are removed, recrystallized and filtered; 2) assistant agent is selected; and 3) the main agent and the auxiliary agent are prepared by the mass ratio of 30 to 50: 30 to 90. The surfactant for displacing the oil of the offshore oilfield and the preparation method thereof have the advantages of ultra-low interfacial tension and good performance of emulsified crude oil, no toxin, no harm to the stratum, good compatibility, cooperation with polymer, microorganism and other flooding agent to displace oil and the like.

The invention relates to a slime water mixed dosing and filter press linkage system and method for coal dressing. According to the invention, a first automatic dosing belt is used for adding an anionic agent into a first funnel, and a second automatic dosing belt is used for adding a cationic agent into a second funnel; the first funnel, a gas ring vacuum pump, a mixing device, a stirring barrel,a chemical storage box, a dosing device, a concentration tank, a filter pressing feeding barrel and a filter press are sequentially connected through connecting pipelines; the second funnel is connected with the stirring barrel; a slime water main pipe is connected with the concentration tank; a feeding concentration meter and a first flow meter are installed on the slime water main pipe; an interface instrument, an underflow concentration meter and a second flow meter are installed in the concentration tank; and an electromagnetic valve, a current measuring meter and a filtrate water flow meter are installed on the filter press. According to the invention, automatic combined dosing is achieved, manpower is reduced, and labor intensity is reduced; agent waste can be effectively reduced, and a dosing process can be more accurately controlled; equipment investment can be reduced, and cost is effectively reduced; and dosing time is shortened and working efficiency is improved.

The invention belongs to the technical field of medicine, especially the field of chemical pharmacy, and relates to a plerixafor-containing composition for injection and a preparation method and application thereof. The plerixafor-containing composition for injection has a pH value of 6 to 8 and is in the form of a stable aseptic aqueous solution of water-soluble plerixafor. According to the invention, solubility of plerixafor in an aqueous solution during dosing is substantially improved, dosing time is reduced, stability of a finished product is improved, and potential safety hazards to patients caused by clarity of the product in clinical medication are avoided.

The invention relates to a method and a device for the compression injection moulding of preforms (10) by means of an injection moulding machine comprising one movable and one fixed tool carrier plate (2, 5) and a mould with a plurality of mould nests or cavities (60), the movable mould half (8) being designed with cores (24) and the melt being introduced into the cavities (60) on the fixed mould-half (9) side via controlled valves. The cores (24) penetrate the mould nests or cavities (60) before completion of the melt dosage to such a depth that said mould nests are at least substantially closed to the exterior. The melt is introduced into the mould nests or cavities (60) when the moulds are not completely sealed, the valves are closed and the compression pressure is produced by means of the cores (24) by the complete closure of the moulds.

The invention provides a pharmaceutical composition of parecoxib sodium for injection and a preparation method thereof. The pharmaceutical composition of parecoxib sodium for injection provided by the invention has the advantages of simple prescription, and the dosage of disodium hydrogen phosphate is greatly reduced compared with the prior art, which is more in line with the requirements of injection drug safety; Quickly, shorten the liquid preparation time, ensure stable quality, and improve production efficiency; the method of rapid freezing and cooling is adopted in the preparation process, so that the freeze-dried product maintains a good pore structure and forms a very uniform particle size, which is conducive to moisture It is fully sublimated; the nitrogen filling operation is omitted, the production process is simplified, the cost is reduced, and it is more conducive to socialized large-scale production.