34results about How to "Promote epithelialization" patented technology

An occlusion device comprises a distal end, a proximal end and an elastic braided body which is provided between the proximal end and the distal end and made of wires. The elastic braided body is composed of a multi-stage braided net, which comprises at least a first-stage braided net that is closest to the distal end and made of a plurality of first-stage wires, and a second-stage braided net which is braided by a plurality of first-stage wires and second-stage wires all together. The minimum cross-section area of the first-stage braided net after being compressed toward the direction perpendicular to an axis of the elastic braided body is less than the minimum cross-section area of any other-stage braided net after being compressed toward the axis. A method for manufacturing the occlusion device is also provided.

The invention relates to the technical field of cosmetics, in particular to a cosmetic or skin care preparation rich in growth factors and a preparation method thereof. The invention provides a growth factor-rich cosmetic or skin care product preparation composed of cell growth factor, small molecule peptide, water, oil, surfactant, moisturizer, antioxidant and preservative and its preparation method. The combination of the formulations of the composition can not only accelerate the metabolism of skin cells, repair the broken superficial dermal fibroblasts, have outstanding and rapid repair functions on skin wounds, but also have the functions of whitening and wrinkle removal, calming and anti-allergic, skin softening, Anti-wrinkle, whitening, refreshing, anti-aging, anti-radiation, prevention and lightening of spots and other functions.

The invention relates to an ocular surface repair film and a preparation method thereof. The preparation method comprises: (1) taking pig small intestine jejunum section, cleaning, radially incision, removing mucosal layer, sarcolemma layer and serosa layer to obtain pig small intestine submucosa tissue membrane; The porcine small intestinal submucosa tissue membrane is respectively soaked in peracetic acid solution and sodium hydroxide solution, taken out and washed to obtain the acellular matrix of porcine small intestinal submucosa tissue; (3) soaking the porcine small intestinal submucosa obtained in step (2) with dopamine solution Tissue acellular matrix, the porcine small intestinal submucosa tissue acellular matrix material was obtained. The acellular matrix material of porcine small intestinal submucosa tissue obtained by the preparation method has relatively suitable mechanical hardness, and such mechanical hardness can ensure that the acellular matrix of porcine small intestinal submucosa tissue can be well attached to the ocular surface.

The invention relates to a wound covering which has good biocompatibility and can accelerate wound healing and a preparation method thereof. The wound covering comprises a thin film; the thin film is made of a carrier with good biocompatibility and high mechanical strength. It is prepared with a protein containing a dopa group; the carrier is collagen; and the protein containing a dopa group is mussel mucin. In the present invention, collagen and mussel mucin are mixed, and a dry membrane is made by semi-lyophilization under low temperature conditions, and then the mussel mucin is fixed on the collagen by chemical crosslinking, and the residual crosslinking agent is removed by rinsing. After being stored in the preservation solution, the stability of the protein structure is enhanced and the activity of collagen and mussel mucin is maintained. The collagen matrix has excellent mechanical strength and can be trimmed into any shape; it can accelerate tissue epithelialization and promote wound healing. Healing; good biocompatibility; no adhesion to the wound surface, no secondary damage to the wound surface.

The invention discloses an inorganic rapid hemostatic material and a preparation method thereof. The inorganic rapid hemostatic material is sepiolite fiber. The present invention has the following beneficial effects: 1. It has the characteristics of quick hemostasis of wound, promotion of wound healing, absorption of body fluid and maintenance of wound humidity; 2. Very strong liquid absorption capacity, the highest water absorption capacity can reach 100%-120% of its own mass; 3. The hemostatic effect is good, which increases the local concentration of platelets and promotes the network of fibrin, so as to achieve the purpose of rapid hemostasis; 4. It can adjust the humidity of the wound surface. release, maintain the humidity of the wound surface, is conducive to cell proliferation and epithelialization, thereby promoting wound healing, and attaching silver nanoparticles to sepiolite fibers has bactericidal and anti-infective effects; 5. High porosity allows oxygen to pass through and isolates bacteria , helps tissue growth; 6. Does not contain organic solvents, binders, and other toxic and harmful substances, and will not pollute the environment after use; 7. Good processing performance and hydrophilicity make this hemostatic material easy to combine with chitosan , alginate, etc. are used as wound materials.

The invention discloses a H2S donor compound capable of being used for skin dressing, sponge dressing and a preparation method, and relates to H2S donor compounds, sponge dressing and preparation methods. The invention firstly aims to provide a H2S donor compound CW-1 capable of being used for skin dressing. The compound can transfer H2S gas molecules to skin specifically and byproducts thereof have the antibacterial action. The invention secondarily aims to provide dressing suitable for skin. The dressing is sponge dressing of calcium alginate comprising the H2S donor compound CW-1. The dressing can be in contact with skin wounds, can transfer H2S gas molecules of a therapeutic dose stably to the skin of wounds effectively, and plays an antibacterial role.

The invention relates to the technical field of tissue engineering and medical wound repairing, in particular to an amnion innate stem cell carried frozen active amnion particle and a conditioned medium and application thereof. Discarded fresh amnions are prepared into particles and then frozen into liquid nitrogen by means of serum-free stem cell freezing liquid; thus, complete matrix components of amnion are maintained while amnion epithelial cell activity is maintained for a long time, and further, disease transmission is avoided effectively. The conditioned medium which is prepared and collected by means of the frozen active amnion particles can promote chemotaxis and migration of human epidermal cells, fibroblast and endothelial cells effectively. In terms of zoografting, wound healing can be improved by multiple ways of regulating inflammatory reaction, promoting vascularization, quickening epithelization and the like through the active amnion particles; further, the amnion matrix can be directly used as a dermis equivalent to induce dermal regeneration so as to improve wound healing quality remarkably. The amnion innate stem cell carried frozen active amnion particle and the conditioned medium thereof can provide simple but effective ways for wound repairing.

The invention discloses a biological sheep membrane for ocular surface treatment and a preparation method thereof. The biological sheep membrane is prepared from sheep membrane through steps of rapid material obtaining, rapid material cutting, and radiation sterilization. The provided biological sheep membrane and preparation method have the following advantages: (1) various natural active components in sheep membrane can be effectively preserved; (2) the anti-inflammation and scar-resistant functions of natural active components in sheep membrane can be effectively preserved; (3) at the same time, the bacteria and viruses in the sheep membrane are completely killed, and thus the safety of the biological sheep membrane can be guaranteed; (4) the biological sheep membrane can be used to repair the damaged tissues, in the early period of treatment, the biological sheep membrane can promote the epithelization; and at the same time the biological sheep membrane can solve the problems that: (a) the material degrades too fast, and the curative effect cannot be achieved; (b) the material degrades too slowly, and the adverse irritation is generated on normal tissue.