48results about How to "No cross-linking reaction" patented technology

The invention discloses a polypropylene foaming material. The polypropylene foaming material comprises the following components according to proportioning by weight: 60-99 parts of polypropylene resin; 0.1-10 parts of nucleating agent; 0.1-5 parts of antioxidant; 0-5 parts of colorant; 0-5 parts of lubricant; and 0-20 parts of filling material; and the melt index of the polypropylene resin is 0.1-20 g / 10 min, and the foaming process adopts supercritical fluid as the foaming agent, i.e. 0.1-20 parts of supercritical fluid (proportioning by weight). The invention also discloses a production method of the foaming material. Compared with the prior art, the invention has the advantages that the universal polypropylene can be adopted as a base material, no polymer is provided, the cross-linking reaction does not occur, the foaming process is free from environmental pollution, and the production method is safe; the quality of the obtained foaming material is stable, the foaming percentage and the cell density are high, the distribution is uniform, and the invention is suitable for the industrial production at a large scale; and meanwhile, the overall production method is simple, the operation is easy, and the production cost is relatively lower.

The invention provides a hydrocarbon fire resistant ultrathin expanded fireproof coating and a preparation method thereof. The coating comprises the following components in part by weight: 10 to 30 parts of epoxy resin, 1 to 4 parts of modified curing agent, 5 to 20 parts of modified resin, 2 to 8 parts of rheological agent, 10 to 35 parts of catalyst, 10 to 25 parts of carbon forming agent, 0 to 11 parts of foaming agent, 5 to 10 parts of fluxing agent, 3 to 10 parts of pigment and filler, and 2 to 5 parts of antibacterial bactericide. The method comprises the following steps of: mixing the crushed resin and other components uniformly, extruding the mixture at the temperature of 95 DEG C at the rotational speed of 300 revolutions per minute, crushing the extruded product, and sieving the powder with a sieve of 40 meshes to obtain the coating. The coating has low curing temperature, high hydrocarbon fire resistant limit, good bonding force and high strength, can tolerate high and low-temperature circulating influence, has air purification and sterilization functions, and is convenient for construction; and the preparation method is simple, and has low energy consumption. The coating is particularly suitable for fire protection of steel, aluminum and other materials of the indoor and outdoor petrochemical industry with hydrocarbon fire risks.

The invention provides a preparation method for hard hollow capsules from enteric plant cellulose derivatives and belongs to the technical field of pharmaceutic adjuvants. Plant cellulose is prepared from plant derivatives such as pine, purified cotton and the like. Colorless and transparent hard hollow capsules, colored hard hollow capsules, shading hard hollow capsules and the like can be prepared though the preparation method. The preparation method comprises steps of mixing of plant cellulose, surfactants, coagulant aids, coloring agents and water, molding, drying, coating and the like. The plant cellulose hard hollow capsules are advantaged by stable performances, low water content, environmental protection and safety. The plant cellulose hard hollow capsules can be filled by all kinds of contents.

The present invention discloses a blast bead sugar and a preparation method thereof. The blast bead sugar comprises a wrapping layer and a sandwich. A cavity is formed inside the wrapping layer; and the sandwich fills the cavity. The preparation method of the blast bead sugar comprises the steps of sandwich solution preparation, wrapping layer preparation, mold pouring and shaping and drying. Theblast bead sugar has a characteristic of blasting and is more interesting when being consumed, the sandwich components are nutritional and healthy, and the wrapping layer uses plant-derived materialsin a breakthrough manner and is safer. Besides, the blast bead sugar is unique in mouthfeel, and the wrapping layer is not liable to crack and strong in stability.

The invention relates to a gellan gum and calcium chloride gelled hydroxypropyl methylcellulose enteric-coated hollow capsule, and belongs to the technical field of the production of hollow capsules. The hollow capsule is characterized in that the hollow capsule is prepared through mixing a main raw material hydroxypropyl methylcellulose with the gellan gum and calcium chloride under a special condition, the hollow capsule has the characteristics of timely disintegration, low water content, suitableness for medicines having strong hygroscopic property and being sensitive to water, small influences of a dissolve-out medium to the shell of the capsule, high drug compliance, long storage duration data, no deterioration within 3-4 years, low condition requirements on the storage and the transportation, difficult crushing in the low humidity environment, difficult deformation, putrefaction and deterioration in the high temperature environment, according with the requirements of populations having all culture backgrounds and religious faiths because of pure vegetable fibers, almost no pollution in the production process, secondary re-dissolving utilization of tailings, omission of the commonly-used surfactants and plasticizers, acceleration of the gelling speed by reducing the gelling temperature only through utilizing calcium chloride to assist the gellan gum, additive reduction, production cost reduction, and suitableness for the mass popularization.

The invention discloses a raw material composition of a cellulose and red alga polysaccharide plant empty capsule. The raw material composition of the cellulose and red alga polysaccharide plant empty capsule comprises the following raw materials in parts by weight: 77.5-98.5 parts of component A, 1.5-22.5 parts of red alga polysaccharide and 0.5-12.5 parts of alcohol, wherein the component A is a cellulose derivative or resin. The invention also discloses the cellulose and red alga polysaccharide plant empty capsule prepared from the raw material composition and a preparation method for the cellulose and red alga polysaccharide plant empty capsule. The plant empty capsule does not deform or crisp in an environment of high temperature, high humidity or cold, is low in moisture content and high in stability, and can be conveniently stored for a long time. Moreover, the requirements on the storage condition are low. Meanwhile, the plant empty capsule is stable in chemical property and has no cross-linking reaction or Maillard reaction or condensation reaction. Various physicochemical indexes of the plant empty capsule, such as disintegration time limit, completely accord with the specifications of the Chinese pharmacopoeia or national standard, and therefore, all defects and potential safety hazards of a gelatin capsule are completely eliminated. The industrial production of the cellulose and red alga polysaccharide plant empty capsule can be realized.

The present invention relates to a hot-set reactive EVA thermo sol. The weight proportion of this material: EVA gum (55-85 shares), increase dimension agent (25-45 shares), crummy peroxide (0.01-0.6 shares), benzoic peroxide (0.01-0.5 shares), 1, 2-divinylbenzene (0.01-0.5 shares). Comparing to normal EVA thermo sol, the present invention obviously increases heat endurance, cohesive strength, bonding action and refractoriness of the EVA thermo sol. The technical level of the EVA thermo sol is increased, and in some aspects, it can replace the PA, PUR, PET thermo sols.

A hypromellose enteric empty capsule gelated by gellan gum and potassium chloride belongs to technical field of empty capsule production, is characterized in that hypromellose is used as a main raw material and mixed with the gellan gum and potassium chloride to prepare the empty capsule, and has the benefits that the disintegration is timely, moisture content is low, the empty capsule is suitable for medicines which have strong hygroscopicity and are sensitive to water, the influence of dissolved mediums on a capsule shell is small, the medication compliance is high, the storage period is long, the empty capsule can not go bad within 3-4 years, requirements on storage and transportation conditions are low, the empty capsule is less susceptible to fragmentation at a low-moisture environment, is insusceptible to deformation at a high-temperature environment, and has low probabilities of rottenness and deterioration; the empty capsule is made from pure vegetable fibers, and can meet requirements of all cultural backgrounds and religious groups; the manufacturing process is almost free from pollution, tailings can be again dissolved for reuse; frequently-used surface-active agents and plasticizers are eliminated, the gelating speed is accelerated only by using the potassium chloride to help the gellan gum to condense so as to reduce the gelating temperature, accordingly, the additives are reduced, and the production cost is reduced; the empty capsule is suitable for mass promotion.

The invention discloses a hydroxypropyl methylcellulose hollow capsule and a production process thereof. The glue solution of the hollow capsule is prepared from the following components: 120.0g of hydroxypropyl methylcellulose HPMC, 3.5g of carrageenan, 10.0g of titanium dioxide mother liquor, 0.08g of lauryl sodium sulfate, 530.0g of pure water and 0-0.15g of pigment. The production process comprises the following steps: preparing the titanium dioxide mother liquor; preparing HPMC sol; adding pigment into the glue solution; dipping glue, baking, demolding, cutting, registering, inspecting, packaging and putting in storage. The preparation process is simple and strong in operability, the capsule product has good molding property, high safety, good reliability and low water content, effectively takes the curative effect of content, is stable in molecule transmission, does not perform crosslinking reaction with the content, is sufficient in solubility, is little impacted by external temperature and humidity, has long preservation period, and is convenient for transporting and storing.

The deep wood chip gel plugging agent is used in water injecting well to plug the high penetrating band in thick oil stratum to lower ineffective water circulation. The deep plugging agent consists of high molecular weight anionic polyacrylamide of molecular weight over 19 million and hydrolysis degree of 25-30 % 0.15-0.5 wt%, phenol compounded polyamine 0.1-0.3 wt%, resorcinol 0.01-0.02 wt%, oxalic acid 0.1-0.2 wt%, wood chip 0.5-2.5 wt% and water 96.48-99.14 wt%, which are compounded into water solution of 0.86-3.52 wt% water solution. The present invention has low use concentration, controllable gel forming time and viscosity, low cost and simple compounding process.

The invention belongs to the technical field of high-molecular materials and particularly relates to a fully-biodegradable polylactic acid thermoplastic elastomer and a preparing method thereof. The polylactic acid thermoplastic elastomer is prepared from component a biology-base vulcanized lactoprene particles, a component b polylactic acid, a component c softening agent and a component d hydrolysis resisting agent; the weight ratio of the component a to the component b is 50:50-75:25, the content of the component c is 10-40 weight parts calculated according to 100 weight parts of the component a, and the content of the component d is 0.5-3 weight parts and 1-2 weight parts preferably calculated according to the total 100 weight parts of the component a and the component c. The polylactic acid thermoplastic elastomer has a full-biodegradation property, good biocompatibility, an excellent mechanical property and can be used as food packaging materials, child toy materials, medical materials and the like.

The invention relates to the technical field of health-care products, in particular to a preparation method of fish oil soft capsules. According to the preparation method disclosed by the invention, glyceride components in unsaturated fatty acid in salmon livers are extracted under mild condition by an enzyme catalysis method, lipase hydrolyzes saturate fatty acid and low unsaturated fatty acid onglyceride of fish oil firstly, hydroxyls are exposed, and then an ester bond synthesis reaction is generated with free EPA and free DHA, so that enriched EPA and enriched DHA are obtained, and the problems of polymerization, oxidation, conjugation, transformation and the like of polyunsaturated fatty acids caused by high temperature are solved; saturated fatty acids in ethyl ester fish oil are removed in a urea adduction manner in the process; and vacuum deodorization is adopted, fishy smell in the fish oil is removed, the palatability is improved, the preparation method is safe, and hazardous substances are not generated.

The invention provides a plant hollow capsule and a preparation method thereof, and belongs to the technical field of hollow capsule production. The plant hollow capsule is prepared from modified hydroxypropyl methylcellulose, gel, coagulant aid, plasticizer, surfactant and the balance of water, wherein the modified hydroxypropyl methylcellulose is prepared by adding a proper amount of microcrystalline cellulose into hydroxypropyl methylcellulose and performing uniform mixing. The plant hollow capsule has the beneficial effects that the capsule as certain moisturizing property besides the molding performance of a hydroxypropyl methylcellulose gel solution can be kept, moisture loss due to dryness and moisture absorption can be avoided in the storing process, shrinkage or expansion of a capsule shell can be avoided, occurrence of powder leakage can be effectively avoided, and the disintegrating speed of a capsule can be accelerated; the ductility and plasticization of the capsule can beimproved by properly adding the plasticizer, uniform wall thickness of the capsule can be guaranteed by combining with the gel; the disintegrating speed can be accelerated by properly adding the surfactant with the microcrystalline cellulose; and the friability can be effectively improved by properly adding the gel and the coagulant aid with the plasticizer.

The invention provides a method for preparing a meta-xylylene diamine epoxy resin, which comprises the following steps of: reacting meta-xylylene diamine with chloroepoxy propane, an additive and alkali at a temperature of between 30 to 85 DEG C; recovering (or not) the rest chloroepoxy propane or meta-xylylene diamine; obtaining the meta-xylylene diamine epoxy resin after processing. The meta-xylylene diamine resin prepared through the method can be cured at a room temperature and be used at a high temperature with low viscosity and a high epoxide number.

The invention discloses a preservative and a preparation method thereof. The preservative comprises the following components in percentage by mass: 0.7-7 parts of isothiazolinone, 0.1-10 parts of a bromine-containing stabilizer and 40-90 parts of water. According to the preservative disclosed by the invention, introduction of heavy metals or nitrates is avoided, the environment is not avoided, andmeanwhile, the physical morphology of a protected product is not damaged. The preservation ensures long-term stability of the protected product, and the content of 5-chloro-2-methylisothiazolinone inthe system is not consumed after the protected product is stored in an environment of 54 DEG C for 30 days. The preservative provided by the invention can be diluted into different concentrations, cross-linking reaction is avoided, and the application range is wide.

The invention discloses a polypropylene foaming material. The polypropylene foaming material comprises the following components according to proportioning by weight: 60-99 parts of polypropylene resin; 0.1-10 parts of nucleating agent; 0.1-5 parts of antioxidant; 0-5 parts of colorant; 0-5 parts of lubricant; and 0-20 parts of filling material; and the melt index of the polypropylene resin is 0.1-20 g / 10 min, and the foaming process adopts supercritical fluid as the foaming agent, i.e. 0.1-20 parts of supercritical fluid (proportioning by weight). The invention also discloses a production method of the foaming material. Compared with the prior art, the invention has the advantages that the universal polypropylene can be adopted as a base material, no polymer is provided, the cross-linkingreaction does not occur, the foaming process is free from environmental pollution, and the production method is safe; the quality of the obtained foaming material is stable, the foaming percentage and the cell density are high, the distribution is uniform, and the invention is suitable for the industrial production at a large scale; and meanwhile, the overall production method is simple, the operation is easy, and the production cost is relatively lower.

The invention relates to a transparent hydrophobic ABS plastic for medical apparatus and instruments, and belongs to the technical field of material preparation. According to the transparent hydrophobic ABS plastic for the medical apparatus and instruments, ABS resin, a solid dispersing agent, a first lubricating agent and a second lubricating agent are adopted as raw materials to prepare the transparent hydrophobic ABS plastic. According to the transparent hydrophobic ABS plastic, the transparent ABS resin is adopted as a main raw material to improve the gloss of the material; meanwhile, thepenetration requirement of ultraviolet rays can also be met. Normal-temperature and high-temperature tests are carried out on a medical instrument prepared from the transparent hydrophobic ABS plasticand ten common medical solvents, and after the tests, the product has no adverse reaction, no precipitation or no crosslinking reaction. In a word, the medical instrument prepared from the transparent hydrophobic ABS plastic for the medical apparatus and instruments has good hydrophobic performance; the medical instrument can form a long-term self-lubricating surface to achieve a hydrophobic effect, the finally prepared medical instrument product is in a semitransparent state, ultraviolet light can penetrate through the medical instrument product, the stability of the medical instrument product system is excellently reflected in different test solvents, and the medical instrument product system is wide in range, safe, reliable and suitable for application and popularization.

The invention discloses a once-forming, fully-glazing and support pin type firing method of small fully-glazed porcelain. A seal is carved in the center of the bottom of the small porcelain related in the method. The fully-glazing and support pin type firing method comprises steps as follows: the part, excluding the seal, of the surface of the porcelain is uniformly dipped with glaze, the seal is taken as a support point, a support seat is used for a support, the porcelain fully dipped with the glaze and the support seat are put into a kiln together to be fired by the aid of support pins, the support seat is a seat plate which is as large as the porcelain and is used for supporting the porcelain, and a trapezoid support bulge matched with the seal is arranged at the center of the top of the seat plate. The method is simple and practical, and the small fully-glazed porcelain can be formed and fired once.

The invention provides a preparation method of poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl)hydrochloride. The method comprises the following steps: (1), polycondensation reaction: firstly, 1,6-hexanediamine dihydrochloride, 1,6-bis(cyanoguanidino)hexane and water are added to an autoclave, nitrogen is introduced to maintain certain pressure in the autoclave, stirring and heatingare performed for a reaction; (2) salting out: the temperature in the autoclave is reduced, water is added to dissolve the material, sodium chloride is added, the mixture is stirred and left to stand,lower water is separated out, and upper poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl)hydrochloride crude product is taken for later use; (3), pH adjustment: water is added to the upper crude product for dissolution, pH is adjusted with a hydrochloric acid solution, and a poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl)hydrochloride aqueous solution is obtained; (4)drying: the aqueous solution is dried, and solid poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl)hydrochloride is obtained. The defect that a solvent and small molecular impurities are difficult to remove in the prior art is overcome, the preparation method has mild reaction conditions and is simple, purity of the obtained product is 98% or higher, the yield can reach 96% or higher,and the method is suitable for large-scale industrial production and application.

A full-glazed branch-fired method for one-time molding of small-sized full-glazed porcelain. The center of the bottom of the small-shaped porcelain involved in the method is all engraved with a seal. The full-glazed branch-fired method is: remove the surface of the porcelain The part outside the seal is evenly soaked with glaze, the seal is used as a support point, and a support seat is used as a support, and the porcelain soaked in glaze together with the support seat can be fired in a kiln together, wherein the support seat is a size A seat plate matching with the porcelain is used to support the porcelain, and a trapezoidal supporting protrusion matching the seal is arranged at the center of the top of the seat plate. The method of the invention is simple and practical, and can produce small vessel-shaped full-glazed porcelain in one molding process.

The invention relates to a thermoplastic polyurethane elastomer with ultralow temperature resistance and high mechanical property and a preparation method of the thermoplastic polyurethane elastomer, and belongs to the field of polyurethane materials. A soft chain segment of the thermoplastic polyurethane elastomer is composed of polytetrahydrofuran ether glycol, and a hard chain segment of the thermoplastic polyurethane elastomer is composed of 4, 4'-dicyclohexylmethane diisocyanate and a novel small-molecule binary secondary amine cyclic chain extender. The thermoplastic polyurethane elastomer with ultralow temperature resistance and high mechanical property is prepared by a two-step method through solution polymerization. The synthesis method is simple, the glass transition temperature can be as low as -104 DEG C, and the material is suitable for an extremely cold environment; and meanwhile, the mechanical property of the thermoplastic polyurethane elastomer is also considered, and the tensile strength reaches up to 47 MPa.

The invention discloses a method for constructing a composite proton exchange membrane by using high-sulfonation-degree polyether-ether-ketone fibers. The method comprises the following specific steps: firstly, soaking high-sulfonation-degree polyether-ether-ketone in a salt solution to replace H<+>, and carrying out electrostatic spinning to obtain a nanofiber membrane in the form of sulfonate; filling pores of the fiber membrane with sulfonated polyetheretherketone to obtain a composite membrane, carrying out thermal crosslinking on an H < + >-form sulfonic acid group in a composite membrane matrix and a benzene ring on a high-molecular main chain under the catalytic action of dimethyl sulfoxide, and because the sulfonic acid group in a sulfonate form is not subjected to a thermal crosslinking reaction, the fiber still has high sulfonation degree after crosslinking. And high proton conductivity is maintained. The composite membrane matrix has good mechanical strength after crosslinking, and the nanofiber constructs a long-range proton transmission channel in the composite membrane, so that the proton exchange membrane shows high proton conductivity.

A hypromellose enteric empty capsule gelated by gellan gum and potassium chloride belongs to technical field of empty capsule production, is characterized in that hypromellose is used as a main raw material and mixed with the gellan gum and potassium chloride to prepare the empty capsule, and has the benefits that the disintegration is timely, moisture content is low, the empty capsule is suitable for medicines which have strong hygroscopicity and are sensitive to water, the influence of dissolved mediums on a capsule shell is small, the medication compliance is high, the storage period is long, the empty capsule can not go bad within 3-4 years, requirements on storage and transportation conditions are low, the empty capsule is less susceptible to fragmentation at a low-moisture environment, is insusceptible to deformation at a high-temperature environment, and has low probabilities of rottenness and deterioration; the empty capsule is made from pure vegetable fibers, and can meet requirements of all cultural backgrounds and religious groups; the manufacturing process is almost free from pollution, tailings can be again dissolved for reuse; frequently-used surface-active agents and plasticizers are eliminated, the gelating speed is accelerated only by using the potassium chloride to help the gellan gum to condense so as to reduce the gelating temperature, accordingly, the additives are reduced, and the production cost is reduced; the empty capsule is suitable for mass promotion.

The invention relates to enteric-coated plant cellulose hard empty capsules and a preparation method thereof. The hard empty capsules are prepared by mixing and processing the following raw materials in percentage by weight: 20-28 percent of plant cellulose derivatives, 10-16 percent of pectin, 0.2-0.25 percent of surfactant, 0.1-5 percent of coagulant aids, 0-0.05 percent of coloring agent, 0-5 percent of titanium dioxide, 0.1-0.5 percent of plasticizer and the balance of water, wherein the surfactant is selected from lauryl sodium sulfate or Tween 80; the plasticizer is selected from glycerin or polyethylene glycol; the coagulant aids are selected from any one or several out of sodium alga acid, agar, carrageenan and cooling gel; and the coloring agent refers to any one out of a synthetic coloring agent, a natural coloring agent and a plant coloring agent. The enteric-coated plant cellulose hard empty capsules disclosed by the invention comprise the main raw materials such as plant cellulose derivatives and pure natural plant polysaccharide pectin, the pectin serving as a main ingredient is uniformly distributed in the hard empty capsules, and the prepared hard empty capsules do not need outer coatings, so that gastric acid resistance can be realized, the hard empty capsules do not disintegrate in the stomach, the hard empty capsules and the contained drugs are not subjected to a cross-linking reaction, and thus the safety is high.

The invention relates to a retarded crosslinked gel, which is prepared from the following raw materials of anionic polyacrylamide, a polyglutamic acid, sodium bichromate, sodium sulfite and water. According to the retarded crosslinked gel, hexavalent chromium ions are firstly complexed with the polyglutamic acid to form a molecular group with certain stability; free hexavalent chromium ions are reduced into trivalent chromium ions by the sodium sulfite; the trivalent chromium ions are crosslinked with the polyacrylamide to form the gel of a mesh structure. The crosslinking rate of the trivalent chromium ions and polyacrylamide is controlled through a dissociation rate of the hexavalent chromium ions in a complexed state, so that retarding the final gelling time. In addition, the polyglutamic acid has a very strong water locking function, so that the gel is not easily bled or broken, the stability of the gel is strengthened, obvious crosslinking reaction is not generated in the production process; the injection pressure is not obviously improved; a working solution is still crosslinked into a semi-flow state polymer gel after being injected into a stratum to generate a profile modification (profile control and displacement) effect.

A hypromellose enteric empty capsule gelated by gellan gum and calcium chloride belongs to technical field of empty capsule production, is characterized in that hypromellose is used as a main raw material and mixed with the gellan gum and calcium chloride to prepare the empty capsule, and has the benefits that the disintegration is timely, moisture content is low, the empty capsule is suitable for medicines which have strong hygroscopicity and are sensitive to water, the influence of dissolved mediums on a capsule shell is small, the medication compliance is high, the storage period is long, the empty capsule can not go bad within 3-4 years, requirements on storage and transportation conditions are low, the empty capsule is less susceptible to fragmentation at a low-moisture environment, is insusceptible to deformation at a high-temperature environment, and has low probabilities of rottenness and deterioration; the empty capsule is made from pure vegetable fibers, and can meet requirements of all cultural backgrounds and religious groups; the manufacturing process is almost free from pollution, tailings can be again dissolved for reuse; frequently-used surface-active agents and plasticizers are eliminated, the gelating speed is accelerated only by using the calcium chloride to help the gellan gum to condense so as to reduce the gelating temperature, accordingly, the additives are reduced, and the production cost is reduced; the empty capsule is suitable for mass promotion.

The invention relates to formulae and properties of seaweed gel plant soft capsule shells. The formula of the seaweed gel plant soft capsule shell comprises 10-30 parts by weight of a seaweed gel, 30-50 parts by weight of a plasticizer, 0.001-0.1 part by weight of a coagulant aid and the balance of water, wherein the water content accounts for 10-20% of the total weight of the capsule shell. The seaweed gel plant soft capsule shell provided by the invention has the characteristics of being colorless and transparent, high in elasticity, high in strength, low in bonding temperature and the like.

The invention provides a method for preparing polyhexamethylene biguanide hydrochloride, the method comprising the following steps: (1) polycondensation reaction: first, 1,6-hexamethylenediamine hydrochloride, 1,6-dicyano Put guanidine hexane and water into the autoclave, ventilate nitrogen to maintain a certain pressure in the still, stir and raise the temperature to react; (2) salting out: reduce the temperature in the still, add water to dissolve the material, then add sodium chloride, leave standstill after stirring, The lower water layer is separated, and the crude product of polyhexamethylene biguanide hydrochloride in the upper layer is set aside; (3) pH adjustment: the crude product of the upper layer is dissolved in water, and the pH value is adjusted with hydrochloric acid solution to obtain polyhexamethylene biguanide hydrochloride Aqueous solution; (4) drying: drying the aqueous solution to obtain solid polyhexamethylene biguanide hydrochloride. The invention overcomes the disadvantages of difficult removal of solvents and small molecular impurities in the prior art, has mild reaction conditions, simple preparation method, the purity of the obtained product is over 98%, and the yield can reach over 96%, which is suitable for large-scale industrial production and application.

The invention discloses a hypromellose enteric-coated hollow capsule with potassium salt and sodium salt gel, which belongs to the technical field of hollow capsule production. Firstly, the hypromellose is stirred into purified water to form a hypromellose solution, and then mixed into the gelatinized Glue to obtain hypromellose colloidal solution, then mixed with potassium salt to obtain hypromellose potassium gel solution, then mixed with sodium salt to obtain hypromellose colloidal solution, and then dipped in glue to make hypromellose sausage Dissolving hollow capsules; the beneficial effect is that the addition of sodium alginate improves the moldability of the colloidal solution, and the solution is first mixed with potassium salt and then sodium alginate, which can greatly reduce the problem of uneven thickness when dipping in the gel; The gel swelling solution is mixed when the temperature of the hypromellose solution is higher than that of the hypromellose solution. Combined with vacuum filtration and degassing, the residual fine air bubbles in the solution can be completely released, basically eliminating the fine air bubbles on the hollow capsule body, and effectively improving Product quality, improve production efficiency.