A kind of hypromellose enteric-coated empty capsule with potassium salt and sodium salt gel

Abstract

The invention discloses a hypromellose enteric-coated hollow capsule with potassium salt and sodium salt gel, which belongs to the technical field of hollow capsule production. Firstly, the hypromellose is stirred into purified water to form a hypromellose solution, and then mixed into the gelatinized Glue to obtain hypromellose colloidal solution, then mixed with potassium salt to obtain hypromellose potassium gel solution, then mixed with sodium salt to obtain hypromellose colloidal solution, and then dipped in glue to make hypromellose sausage Dissolving hollow capsules; the beneficial effect is that the addition of sodium alginate improves the moldability of the colloidal solution, and the solution is first mixed with potassium salt and then sodium alginate, which can greatly reduce the problem of uneven thickness when dipping in the gel; The gel swelling solution is mixed when the temperature of the hypromellose solution is higher than that of the hypromellose solution. Combined with vacuum filtration and degassing, the residual fine air bubbles in the solution can be completely released, basically eliminating the fine air bubbles on the hollow capsule body, and effectively improving Product quality, improve production efficiency.

Description

Technical field[0001]The invention belongs to the technical field of hollow capsule production, in particular to a plant-based enteric hollow capsule prepared by using hypromellose as a raw material and gelled with potassium salt and sodium salt.Background technique[0002]The hollow capsule is composed of a cap and a body two capsule shells refined from medicinal materials, which are used to contain solid medicines; such as self-made powders, health care products, medicines, etc., which solve the problem of difficult intake and poor taste for users, and truly realize The good medicine is no longer bitter; because hollow capsules are easy to swallow, they can effectively cover up the uncomfortable taste and smell of the contents, and they are becoming more and more popular with patients.[0003]The previous hollow capsules mainly include animal gelatin capsules and various vegetable capsules. In view of the various defects of the existing capsules, the company developed and applied for ...

AI Technical Summary

Problems solved by technology

However, after several years of production and use practice, it is found that when the patented method is used to produce hollow capsules, the proportion of microbubbles and uneven thickness on the capsule body is too large, and often about 30% of the products are unqualified, resulting in low production efficiency.

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