53results about How to "Increase residence time" patented technology

An elongated intravascular device having a frame configured for reversibly expanding in a patient's body lumen, which has a sleeve secured to the frame, and at least one sleeve-folding strut configured to fold the sleeve inwardly as the frame radially collapses in the patient's body lumen. Additional aspects of the invention are directed to methods of recovering such expanded frame type devices, and a recovery catheter configured for collapsing an expanded frame. The devices and methods of the invention facilitate the collapse of expanded frame devices, for repositioning or removal from the patient's body lumen.

The present invention provides a hydrophobic group-introduced hyaluronic acid derivative comprising at least one repeating unit represented by the formula (I):wherein R1, R2, R3, R4, Z, n, Ra, Y, and X1 are as defined in the specification.

Provided herein are methods and recombinant expression systems for the production of recombinant glycoproteins that have increased sialic acid content and contain predominantly alpha2-6 sialic acid linkages. Also provided herein are recombinant glycoproteins that have an increased in vivo circulatory half-life. One potential application of the glycoproteins described herein is for the treatment and prophylaxis of poisoning by neurotoxins.

The invention relates to a continuous preparation process for an environment-friendly plasticizer and a device used in the process. The process comprises the following steps of: enabling solid terephthalic acid and isooctyl alcohol which serve as raw materials to react in the existence of an esterification catalyst and an antioxidant for continuously preparing dioctyl terephthalate (DOTP); pulpifying the solid terephthalic acid in the isooctyl alcohol until the particle size of the solid terephthalic acid reaches 5 to 20 mu m; adding the isooctyl alcohol so as to adjust the mole ratio of alcohol to acid in pulp liquid as 2:1 to 4:1; adding into a slurry tank, preheating, and entering a reaction kettle from the bottom; reacting with the preheated isooctyl alcohol which enters from the bottom of the reaction kettle in the reaction kettle in the existence of the esterification catalyst and / or the antioxidant; reacting until an acid value decreases to be below 2, and continuously feeding the raw materials namely the solid terephthalic acid and the isooctyl alcohol; and adding the DOTP which is generated in reaction from the upper part of the reaction kettle to a product tank, condensing the isooctyl alcohol which does not completely reacts and the generated steam through a condenser on the top of the reaction kettle, separating through an oil water separator, and entering an octyl alcohol tank for recirculation.

The present invention relates to a preparation method of a novel dermal filler. The method adopts low-toxic amino acid and its derivatives as cross-linking agent to prepare cross-linked sodium hyaluronate gel; Mild and easy to handle and other advantages, the basic amino acids-lysine and arginine or their derivatives among the essential amino acids for the human body are selected as the cross-linking agent to undergo a cross-linking reaction with the carboxyl end of the sodium hyaluronate molecule, and then partially seal the body The recognition site of hyaluronidase delays the recognition and degradation of the enzyme, and finally increases the residual time in the body. It provides a new technology for the development of safe and long-acting sodium hyaluronate injectable cosmetic fillers. Better market development prospects.

Production of vinyl polymers by the polymerization of vinyl monomers in a planetary gear extruder.

The invention relates to a nitrogen stabilizer comprising the following materials in percentage by weight: 30%-50% of calcium base bentonite, 15%-30% of humic acids and 10%-30% of thiourea. Compared with the prior art, the nitrogen stabilizer can effectively prolong the residence time of nitrogen, thereby effectively prolonging the fertilizer effect period and enhancing the utility ratio; in addition, the nitrogen stabilizer has low price, flexible use, convenient and easy preparation, and the like and is suitable for various nitrogenous fertilizers, thereby being an optimal stabilizer for producing various long-acting slow-release nitrogenous fertilizers and long-acting slow-release compound fertilizers.

An improved chemical looping combustion (CLC) process and system includes a hopper containing oxygen carrier particles, e.g., metal oxides, that are gravity fed at a controlled rate of flow from the hopper into (a) a generally vertical downflow reactor where they are mixed with all of the hydrocarbon fuel feed to the system and (b) into one or more standpipes that are in communication with a plurality of staged fluidized reactor beds, the amount of the oxygen carrier particles introduced into the system being stoichiometrically predetermined to produce a syngas mixture of H2 and CO2; or to complete combustion of the fuel to CO2 and water vapor, thereby permitting capture of a majority of the CO2 produced in an essentially pure form.

The invention discloses a quadruple linkage bad breath eliminating composition toothpaste which comprises an active ingredient consisting of the following components in percentage by weight: 0.5-1.5% of tea polyphenol, 0.5-1% of L-Ascorbic-acid-2-phosphate sodium, 1-3% of beta-cyclodextrin and 0.3-2% of a PVM / MA copolymer, and the balance being a toothpaste substrate. The toothpaste disclosed by the invention, through a linkage effect of four active ingredients, not only takes efficacy of single ingredient but also realizes a synergistic effect of all functional ingredients; by using the quadruple therapy to oral cavity, the toothpaste can inhibit odor inducing bacteria in the oral cavity through effective release of antibacterial ingredients in a process of brushing teeth; through an absorbent, bad breath in the oral cavity is absorbed; through absorption and film forming functions of the high-molecular copolymer, effective release of the active ingredients is guaranteed and residence time in the oral cavity is prolonged; meanwhile, a normal microorganism environment in the oral cavity is maintained, and effects of treating both symptoms and root causes and freshening breath for a long time are achieved, so as to meet requirements of people for improving images and pursuing healthy and green life.

The invention relates to a reaction vessel in which hydrogen sulphide is prepared from sulphur and hydrogen, wherein the reaction vessel consists partly or entirely of a material which is resistant to the reaction mixture, its compounds or elements and retains its resistance even at high temperatures.

The invention provides a moisturizing gel lotion and a preparation method thereof. The moisturizing gel lotion comprises the following raw materials: rosehip oil, a centella asiatica extract, grape seed oil, vitamin E, isopropyl myristate, PEG-7 olive oil ester, lecithin, alkyl glucoside, sodium alginate, 1,2-propanediol, water, stearyl alcohol, ethyl cellulose, sodium stearyl hyaluronate, butylene glycol cocoate, methylparaben, xanthan gum, xanthan gum, carbomer and citric acid. The preparation method comprises the following steps: firstly preparing an emulsion from the rosehip oil, the centella asiatica extract, the grape seed oil, the vitamin E and the PEG-7 olive oil ester, and then adding a hydrogel matrix, namely the xanthan gum, the xanthan gum and the carbomer, to obtain the moisturizing gel lotion. On one hand, the using amount of a surfactant in a common emulsion is reduced, and irritation is reduced; on the other hand, the water-retaining and skin-care advantages of hydrogelare effectively utilized, so that the acting residence time of moisturizing components is further prolonged.

The invention discloses a water-saving and energy-saving ammonia desulphurization ultra-clean discharge system and process capable of preventing ammonia from escaping from aerosol. The system comprises a slurry disturbance system, a cooling concentration crystallization system, a sulfur oxide absorption system, an ammonia capture system, a washing purification system and a crystal particle enlarging system, circulating spray liquid of the desulfurizing tower from bottom to top adopts solutions with different components, and the concentration gradient is decreased progressively so that the desulfurizing efficiency is effectively improved, escape of aerosol and ammonia is avoided, and the phenomena of trailing and falling of ammonia-process desulfurized flue gas are eliminated. Different technologies such as multi-stage cyclone coupling, packing, a demister, an efficient cyclone water film dust collector and a wire mesh demister are combined, optimization of the distribution condition offlue gas in the tower is achieved, the retention reaction time of the flue gas is prolonged, further coagulation of fine particles and trapping of slurry droplets are promoted, the flue gas is washedthrough low-temperature washing liquid of the external cooling tower, cooperative removal of the fine particles is achieved, and ultra-clean emission is achieved.

The invention discloses an unpowered mixing and low temperature resistant biochemical treatment device for rural (community) sewage mud liquid, and the device includes a floating precipitation separation pool, a baffle mixed fermentation pool and an efficient biochemical treatment pool. The middle of the floating precipitation separation pool is communicated with the baffle mixed fermentation tank through a stream guidance tube, the upper part of the baffle mixed fermentation tank enters into the bottom of the efficient biochemical treatment pool through a three-way stream guidance tube, and the upper part of the efficient biochemical treatment pool through a stream guidance tube enters into a depth treatment facility or external environment. The baffle mixed fermentation tank is provided inside with a baffle plate, and stereo elastic packing suitable for biological biofilm culturing is suspended in the efficient biochemical treatment pool. The invention optimizes the process of a traditional three-case septic tank, extends the residence time of waste water, improves the degree of mixing of sewage and activated sludge, utilizes the geothermal to improve the treatment effect of sewage in winter, and has the characteristics of low cost, low operation cost, high efficiency, and easy popularization.

The invention discloses a combined fluidized bed type gas-solid heat exchange device utilizing waste heat of furnace slag. The device comprises a gas-solid heat exchange body, and an air outlet is arranged at the top of the gas-solid heat exchange body. The device is characterized in that two partition walls are arranged in the gas-solid heat exchange body, connect a front faceplate with a rear faceplate of the same and divide a cabin inside the gas-solid heat exchange body into a left bubbling bed cabin, a spouted bed cabin and a right bubbling bed cabin, the left and right bubbling bed cabins are symmetrically arranged on two sides of the spouted bed cabin, the upper portions and the lower portions of the three cabins are communicated respectively, an independent air chamber is arranged at the bottom of each cabin, a dense-hole-type air distribution plate is arranged above the air chamber in the spouted bed cabin, a left air-cap-type air distribution plate and a right air-cap-type air distribution plate are arranged at the tops of the air chambers in the left and right bubbling bed cabins respectively, and the left air-cap-type air distribution plate is connected with the dense-hole-type air distribution plate through a second dense-hole-type air distribution plate and a first orthostomous section. The combined fluidized bed type gas-solid heat exchange device has good gas-solid heat exchange effect and can be widely applied in the field of steel and iron and power.

A method of controlling at least part of a start-up or re-light process of a gas turbine engine, the method comprising: controlling ignition within a combustion chamber of the gas turbine engine; controlling rotation of a low pressure compressor using a first electrical machine, and controlling rotation of a high pressure compressor using a second electrical machine, the combustion chamber downstream of the low pressure compressor and high pressure compressor; determining if an exit pressure of the high pressure compressor is equal to or greater than a self-sustaining threshold pressure; and in response to determining that the exit pressure of the high pressure compressor is equal to or greater than the self-sustaining threshold pressure, ceasing controlling rotation of the low pressure compressor using the first electrical machine, and / or the high pressure compressor using a second electrical machine.

A composition and method for the removal of biological fouling from wetted surfaces intermittently or continuously in contact with water is disclosed. The method includes the steps of preparing a cleaning composition of basic pH from a strong base and an active oxygen donor component, applying the composition to the surface to be cleaned, and after a selected residence time, removing any unreacted cleaning composition and all removed fouling by rinsing or flushing with water.

The invention provides a primary air coal dust airflow gasification device of a boiler for ignition and stabilization of combustion of the boiler. The device comprises a cyclone separator, a Rafa mixer, a gasification reactor and a central tube arranged on the top of the cyclone separator. A first inlet tube and a second inlet tube are symmetrically formed in the upper portion of the cyclone separator tangentially and the second inlet tube communicates with the outlet of the gasification reactor; a straight tube which is arranged in the bottom of the cyclone separator communicates with a throat of the Rafa mixer; and one side of the outlet of the Rafa mixer communicates with the inlet of the gasification furnace through a connecting pipeline. The coal dust airflow is gasified before entering the boiler by means of an external energy source. In addition, high-temperature flue gas of the part is extracted from the outlet of the hearth of the boiler and a part of heat is released in the hearth of the boiler. Compared with a technology of gasifying the coal dust by other forms of energy sources such as electric energy, flue gas waste heat of the boiler is fully used, so that the device is better in economical benefit.

The invention discloses a method for preparing optothermal responding short fiber by using recycled polyester bottle chips and belongs to the field of chemical fiber production. The method comprises the steps of drying optothermal responding masterbatch and recycled polyester bottle chips, mixing, carrying out screw melt extrusion on a mixture to obtain a melt, and performing filtering, melt spinning, cool-forming, coiling and oiling, drafting and feeding, receiving and barrel charging, bundling, drafting, oiling, yarn pilling, coiling, thermal setting and cutting to obtain the optothermal responding short fiber. The optothermal responding short fiber is prepared through optothermal responding masterbatch and recycled polyester bottle chip mixing and melt spinning, the preparation method is reasonable, highly operable and easy to industrially implement, the prepared optothermal responding short fiber is used mainly in textile products such as automobile trims, casement fabric and decorative fabric and has the excellent functions such as near-infrared and visible light absorption, heat accumulation and discharge, and temperature adjustment.

The invention discloses a slag discharging device of a biomass circulating fluidized bed boiler. The slag discharging device of the biomass circulating fluidized bed boiler comprises a combustion chamber, wherein a boiler-front feeding device is connected above the combustion chamber, a large slag discharging pipe and a disintegrating slag discharging pipe are arranged below the combustion chamber, a horizontal plate is arranged on one side of the bottom of the combustion chamber, a single V-shaped screening bucket is arranged on the other side of the bottom of the combustion chamber, and located at the inclined lower part of the horizontal plate, the large slag discharging pipe is communicated with the single V-shaped screening bucket, the disintegrating slag discharging pipe is communicated with the horizontal plate, and a rotating vortex device is arranged in the single V-shaped screening bucket. The slag discharging device of the biomass circulating fluidized bed boiler has the advantages of capability of solving the problems of bad fuel adaptability, unsmooth slag discharging and the like caused by massive inert materials doped in a variety of biomass and fuel combusted by the biomass fuel circulating fluidized bed boiler, and the technical advantages of uniform air distribution, efficient fuel combustion, small abrasion of a heating surface, good equipment economy and high reliability.

The invention relates to a continuous preparation process for an environment-friendly plasticizer and a device used in the process. The process comprises the following steps of: enabling solid terephthalic acid and isooctyl alcohol which serve as raw materials to react in the existence of an esterification catalyst and an antioxidant for continuously preparing dioctyl terephthalate (DOTP); pulpifying the solid terephthalic acid in the isooctyl alcohol until the particle size of the solid terephthalic acid reaches 5 to 20 mu m; adding the isooctyl alcohol so as to adjust the mole ratio of alcohol to acid in pulp liquid as 2:1 to 4:1; adding into a slurry tank, preheating, and entering a reaction kettle from the bottom; reacting with the preheated isooctyl alcohol which enters from the bottom of the reaction kettle in the reaction kettle in the existence of the esterification catalyst and / or the antioxidant; reacting until an acid value decreases to be below 2, and continuously feeding the raw materials namely the solid terephthalic acid and the isooctyl alcohol; and adding the DOTP which is generated in reaction from the upper part of the reaction kettle to a product tank, condensing the isooctyl alcohol which does not completely reacts and the generated steam through a condenser on the top of the reaction kettle, separating through an oil water separator, and entering an octyl alcohol tank for recirculation.

The present invention provides a method for rapidly and reliably delivering dantrolene, or derivatives thereof, alone or in combination with other compounds, to the systemic circulation by administration via the nasal route to produce rapid onset of beneficial effects in the treatment or prevention of malignant hyperthermia (MH), spasticity, and Ecstasy intoxication. The present invention further provides intranasal pharmaceutical compositions comprising dantrolene sodium or any pharmaceutically acceptable salts thereof in a variety of pharmaceutical dosage forms, with and without other compounds.

The invention discloses a chemical catalysis reactor, comprising a reaction tank body. A material inlet is arranged in the lower end of the reaction tank body; a material outlet is arranged in the lateral wall of the reaction tank body; a first flow baffle and a second flow baffle are arranged inside the reaction tank body from bottom to top, so that the inside of the reaction tank body is divided into a feeding cavity, a discharging cavity and a backflow cavity from bottom to top; an ascending pipe communicating the feeding cavity with the backflow cavity is arranged between the first flow baffle and the second flow baffle; a backflow pipe communicating the backflow cavity with the discharging cavity is arranged on the second flow baffle; and a material outlet is located between the first flow baffle and the second flow baffle and is communicated with the discharging cavity. The chemical catalysis reactor provided by the invention is in an integrated structure, has small occupied area, and is convenient to popularize and apply. During the catalysis reaction, catalyst can be directly output through the material inlet, or the catalyst can be attached to the inside of the metal reaction tank body, through a plurality of tests, the chemical catalysis reactor provided by the invention has the advantages of simple structure, large market prospect and wide application range.

The invention discloses mosquito repellent IR3535 loaded ethyl cellulose microparticles and a preparation method thereof. The mosquito repellent IR3535 loaded ethyl cellulose microparticles have a core-shell structure in which the core is mosquito repellent IR3535 and the shell is ethyl cellulose; at 25 DEG C, the mean grain size of the mosquito repellent IR3535 loaded ethyl cellulose microparticles ranges from 500nm to 5873nm. The preparation method comprises the steps: dissolving polyvinyl alcohol and an emulsifier Tween80 in deionized water at the room temperature, and stirring so that the polyvinyl alcohol and the emulsifier Tween80 are dissolved into a water phase; dissolving the IR3535 and the ethyl cellulose and span-80 in methyl acetate to obtain a mixture as an oil phase; mixing the obtained oil phase with the water phase, homogenizing and emulsifying to obtain an emulsion; and continuing stirring at the room temperature, centrifuging after the methyl acetate volatilizes completely, thus finally, obtaining the mosquito repellent IR3535 loaded ethyl cellulose microparticles having an embedding rate ranging from 33.5% to 77.1%.

The invention provides a method for wrapping peppermint oil microcapsules, which comprises the following steps: preparing an emulsifier solution containing 5-10% of an emulsifier which is a compound of Arabic gum and carbopol in a ratio of 1: 1-5: 1; mixing the emulsifier with the aqueous solution to obtain a water phase; mixing peppermint oil, N-(2-hydroxypropyl) methacrylamide and caprylic / capric triglyceride, and uniformly stirring to obtain an oil phase; adding ammonium persulfate into 30 times of water to prepare an initiator; mixing the water phase and the oil phase to form an emulsion; and introducing nitrogen into the prepared emulsion, adding the prepared initiator after 30-45 minutes, stirring, and reacting at room temperature for 2-4 hours, thereby obtaining the product. According to the peppermint oil microcapsule disclosed by the invention, a material, namely carbopol, with biological adhesion is added and compounded with N-(2-hydroxypropyl) methacrylamide, so that the residual time of the peppermint oil microcapsule in an oral cavity is prolonged, and a slow release effect can be achieved.

The invention discloses anti-halitosis toothpaste. The toothpaste comprises the following effective components: apple polyphenol, cetylpyridinium chloride, a PVM / MA copolymer, zinc gluconate and Vc magnesium phosphate. The anti-halitosis toothpaste disclosed by the invention is safe, reliable and obvious in deodorization effect.

The invention provides a sodium bicarbonate contained oral care composition as well as a preparation method and application thereof. The oral care composition contains sodium bicarbonate, zeolite andhydroxypropyl methyl cellulose, wherein the weight ratio of the sodium bicarbonate to the zeolite is 1 to (1-3), and the weight ratio of the sodium bicarbonate to the hydroxypropyl methyl cellulose is1 to (0.02-0.2). The oral care composition provided by the invention can be applied to preparation of an oral care product, and the dosage of the oral care composition is 5-35 percent of the total weight of the oral care product. For the oral care composition provided by the invention, the sodium bicarbonate is wrapped in a zeolite cavity through a special preparation process, so that the contentof free sodium bicarbonate in the composition as a product is effectively lowered, so that a formula keeps good stability when a sufficient amount of sodium bicarbonate is contained, and the composition is difficult in decomposition and air expansion; and in addition, by adding the hydroxypropyl methyl cellulose, the sodium bicarbonate is long in time of remaining in an oral cavity and extends between teeth for friction contact to achieve the effects of deeply cleaning the oral cavity, whitening and strengthening the teeth and nursing gingiva.

The invention relates to an ANGPTL4 polypeptide for use in the preservation of vascular endothelial cell barrier integrity and reduction in no-reflow phenomenon with myocardial infarction.

The invention discloses a chemical chain gasification reaction device and method. The device is a solid particle circulation loop composed of an air reactor, a lifting pipe, a cyclone separator, a return feeder and a fuel reactor. The fuel reactor comprises a gasification reactor at the lower part and a reforming reactor at the upper part which are connected through a contracted rectangular nozzle; fuel is gasified in the gasification reactor, and eluted coke and tar enter the reforming reactor through the rectangular nozzle and are catalytically converted into synthesis gas; and the reduced oxygen carrier enters the air reactor through the return feeder for oxidation and regeneration, enters the cyclone separator through the lifting pipe for separation, enters the reforming reactor through the return feeder, and falls into the gasification reactor through the rectangular slit, so that the cyclic utilization of oxygen carrier particles in the circulating fluidized bed is completed. The device reduces the pressure drop of the reactor and effectively saves the energy consumption of a fan through staged fluidization of the fuel reactor and fluidization reconstruction.