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Quadruple linkage bad breath eliminating composition toothpaste

A combination and linkage technology, applied in dentistry, oral care, medical science, etc., can solve problems such as unfavorable oral health, poor compatibility, and damage to the normal microbial environment of the oral cavity.

Active Publication Date: 2015-01-07
广东名臣日化有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for patients with bad breath, traditional clean toothpaste can no longer meet the daily care requirements, and some toothpastes that claim to have the effect of eliminating bad breath mostly use synthetic antibacterial agents that can inhibit the bacteria that produce volatile sulfides, which are easy to damage the oral cavity while antibacterial and sterilizing. Normal microbial environment, there are certain toxic and side effects, which is not conducive to the health of the oral cavity
For patients with obstinate ammonia odor caused by Helicobacter pylori, there are fewer bad breath toothpastes to choose from at present, and some use chemical drugs that can inhibit and kill Helicobacter pylori. Dysregulation, growing bacterial resistance, poor long-term outcomes
Although some traditional Chinese medicine ingredients are used, or because the ingredients are single, or because of poor compatibility, the effect of removing bad breath is not good.

Method used

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  • Quadruple linkage bad breath eliminating composition toothpaste
  • Quadruple linkage bad breath eliminating composition toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Calculated by weight percentage, formula is as follows:

[0032] Abrasive (abrasive silica) 16%, abrasive (thickened silica) 6%, binder (sodium carboxymethylcellulose) 0.5%, binder (carrageenan) 0.3%, foam Agent (sodium lauryl sulfate) 2.0%, foaming agent (sodium lauroyl sarcosinate) 0.5%, sodium saccharin 0.25%, humectant (polyethylene glycol-400) 3%, humectant (sorbitol) 45% , 1.2% essence, 0.5% tea polyphenol, 0.6% sodium vitamin C phosphate, 1% β-cyclodextrin, 0.5% PVM / MA copolymer, appropriate amount of pH regulator (sodium hydroxide), and the balance of water.

[0033] Preparation method: Add tea polyphenols, vitamin C sodium phosphate, and sodium saccharin into water to dissolve to form a water phase; uniformly disperse the PVM / MA copolymer in polyethylene glycol, and then add the water phase under stirring to make the PVM / MA The copolymer is fully swollen in water; then sodium hydroxide dissolved in a small amount of water is added to the water phase; finally, ...

Embodiment 2

[0035] Calculated by weight percentage, formula is as follows:

[0036] Abrasive (high friction silica) 12%, abrasive (thickened silica) 6%, binder (sodium carboxymethylcellulose) 0.5%, binder (carrageenan) 0.3%, foam Agent (sodium lauryl sulfate) 2.0%, foaming agent (sodium lauroyl sarcosinate) 0.5%, sodium saccharin 0.25%, humectant (polyethylene glycol) 3%, humectant (sorbitol) 45%, essence 1.2%, 0.8% tea polyphenols, 0.8% sodium vitamin C phosphate, 2% β-cyclodextrin, 1% PVM / MA copolymer, appropriate amount of PH regulator (sodium hydroxide), and the balance of water.

[0037] Preparation method is the same as example 1.

Embodiment 3

[0039] Calculated by weight percentage, formula is as follows:

[0040] Abrasive (high friction silica) 18%, abrasive (thickened silica) 4%, binder (sodium carboxymethylcellulose) 0.5%, binder (carrageenan) 0.3%, foam Agent (sodium lauryl sulfate) 2.0%, foaming agent (sodium lauroyl sarcosinate) 0.5%, sodium saccharin 0.25%, humectant (polyethylene glycol) 3%, humectant (sorbitol) 45%, essence 1.2%, tea polyphenols 1.2%, vitamin C sodium phosphate 0.8%, β-cyclodextrin 2.5%, PVM / MA copolymer 1.5%, PH regulator (sodium hydroxide) appropriate amount, water balance.

[0041] Preparation method is the same as example 1.

[0042] Test of halitosis-removing effect of toothpaste with quadruple-linkage halitosis-removing composition

[0043] ①Testing requirements and judgment methods

[0044] The test subject extruded 2cm of the test paste on the toothbrush to ensure 2 minutes of brushing time.

[0045] Using the Halimeter breath detector, test the breath value of the subjects befo...

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Abstract

The invention discloses a quadruple linkage bad breath eliminating composition toothpaste which comprises an active ingredient consisting of the following components in percentage by weight: 0.5-1.5% of tea polyphenol, 0.5-1% of L-Ascorbic-acid-2-phosphate sodium, 1-3% of beta-cyclodextrin and 0.3-2% of a PVM / MA copolymer, and the balance being a toothpaste substrate. The toothpaste disclosed by the invention, through a linkage effect of four active ingredients, not only takes efficacy of single ingredient but also realizes a synergistic effect of all functional ingredients; by using the quadruple therapy to oral cavity, the toothpaste can inhibit odor inducing bacteria in the oral cavity through effective release of antibacterial ingredients in a process of brushing teeth; through an absorbent, bad breath in the oral cavity is absorbed; through absorption and film forming functions of the high-molecular copolymer, effective release of the active ingredients is guaranteed and residence time in the oral cavity is prolonged; meanwhile, a normal microorganism environment in the oral cavity is maintained, and effects of treating both symptoms and root causes and freshening breath for a long time are achieved, so as to meet requirements of people for improving images and pursuing healthy and green life.

Description

technical field [0001] The invention relates to a green, safe and effective toothpaste composed of four-linkage method for eliminating halitosis. technical background [0002] With the rapid development of social economy, people communicate more frequently and pay more attention to their own image. Oral health care is particularly important, especially for people with peculiar mouth odor, which will adversely affect communication and even reduce the quality of communication. According to domestic and foreign epidemiological surveys, a considerable proportion of adults suffers from halitosis in social interactions, and the prevalence rate is 20% to 83%. Another study shows that 80% to 90% of bad breath is caused by oral factors, which is commonly referred to as oral halitosis. Oral bad breath is generally divided into sulfur odor and ammonia odor. Most patients with sulfur odor are caused by anaerobic bacteria in the oral cavity decomposing food residues or proteins in exfol...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61K8/49A61K8/73A61K8/67A61K8/86A61Q11/00
Inventor 葛华亭王彪张太军崔凤玲程双印李涛邹振海陈岱宜
Owner 广东名臣日化有限公司
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