55results about How to "Guaranteed sustained release effect" patented technology

The invention discloses a biological preparation capable of preventing and treating human gastric diseases, i.e., an anti-Helicobacter pylori specific yolk immunoglobulin (anti-HP-IgY) preparation, and especially to a novel dosage form thereof, i.e., a floating tablet in stomach, and the invention belongs to the technical field of biomedicines. The anti-HP-IgY gastric floating tablet uses yolk immunoglobulin specifically resisting Helicobacter pylori (i.e., anti-HP-IgY) as an active component and hydrophobic pharmaceutic adjuvants and hydrophilic pharmaceutic adjuvants as auxiliary components. The gastric floating tablet enables retention time of the active component (anti-HP-IgY) in stomach to be prolonged, which is very helpful for anti-HP-IgY in killing of Helicobacter pylori Hp intermittently floating upward from pylorus; the anti-HP-IgY gastric floating tablet has the advantages of strong specificity, no drug resistance, no toxic and side effects and good thermal stability, acid resistance and antiprotease performance. Raw materials for preparing the tablet are easily available, and a manufacturing method for the table is simple and is convenient for popularization and utilization.

The invention provides memantine hydrochloride sustained release micro-pill tablets and a preparation method thereof. The memantine hydrochloride sustained release micro-pill tablets are prepared by directly pressing self-protected multi-layer micro-pills, and a filling agent, a disintegrating agent and other auxiliary tablet materials do not need to be added. The self-protected multi-layer micro-pill is composed of a pill core, a medicine layer, a sustained release layer, a protective layer and a compressible composite auxiliary material layer, can tolerate extrusion of a certain tabletting pressure, and contributes to keeping the integrity of a micro-pill sustained release coating and good sustained release properties of the medicine. The self-protected multi-layer micro-pill also has high compressibility, disintegration and lubricating property and can be directly pressed into tablets, and the prepared memantine hydrochloride sustained release micro-pill tablets have good drug content uniformity.

The invention provides a biomass charcoal-based fertilizer which comprises the following components in parts by weight: 20-25 parts of urea, 25-31 parts of a phosphate fertilizer, 16-28 parts of a potash fertilizer, 9-11 parts of biomass charcoal, 1-2 parts of fulvic acid, 1-7 parts of organic matters and 1-2 parts of a condiment, wherein the condiment is a mixture of an anti-caking agent, bentonite and a coating agent. Due to adoption of the organic matters and the fulvic acid, sufficient organic nutrients can be provided for crops to grow, and growth and development of plants can be promoted; due to adoption of the fulvic acid, on one hand, a synergetic effect on the urea, the phosphate fertilizer and the potash fertilizer in the biomass charcoal-based fertilizer can be achieved, and theutilization rate of the organic nutrients by the crops can be increased; with the combination of biomass charcoal, the fulvic acid and the organic matters, the fulvic acid and the organic matters canbe slowly released from the biomass charcoal, the fertilizer effect can be prolonged, the organic nutrients can be further enriched, and meanwhile the utilization rates of nutrients can be increased.

The invention discloses sustained-release tea-containing plastic grains and a preparation method thereof. The sustained-release tea-containing plastic grains mainly comprise the following components in part by mass: 10 to 40 parts of tea powder, 50 to 80 parts of adhesive and 5 to 10 parts of foaming agent. Fine and dense pores are formed in the grains formed in the invention, so the tea powder in the grains can function, and the adhesion by the adhesive ensures the sustained-release effect of the active ingredients. As fillers, the sustained-release tea-containing plastic grains can reduce the consumption of tea leaves, have long service life and lower the requirement on the external material of tea health-care products.

The invention belongs to the technical field of a medicine preparation, and discloses an intragastric floating sustained release tablet of a praziquantel composition and a preparation method thereof. The intragastric floating sustained release tablet of the praziquantel composition comprises the following raw materials: 65-85 parts of praziquantel, 50-60 parts of hydroxypropyl-beta-cyclodextrin, 40-60 parts of hydroxypropyl methyl cellulose, and 30-50 parts of xanthan gum. The intragastric floating sustained release tablet of the praziquantel composition provided by the invention is good in sustained release effect, and the blood concentration curve of praziquantel after medicine administration is smoother, the bioavailability of the praziquantel is significantly improved, and popularization and application of the praziquantel are facilitated.

The invention discloses a complete complex fertilizer and a production method thereof. The complete complex fertilizer comprises, in percent by mass, 30-60 parts of potassium dihydrogen phosphate, 30-60 parts of potassium nitrate, 1-5 parts of EDDHA iron,1-5 parts of EDTA zinc-manganese-molybdenum, 1-5 parts of copper amino acid,1-5 parts of liquid complex organic boron, and 1-5 parts of a polyvinyl alcohol solution with the concentration of 1%. The production method for the complete complex fertilizer comprises the following steps: mixing potassium dihydrogen phosphate and potassium nitrate successively with EDDH iron, EDTA zinc-manganese-molybdenum and copper amino acid in a granulator, uniformly mixing, then gradually spraying a mixture of liquid organic boron and polyvinyl alcohol, and performing granulation molding and drying, so as to obtain the complete complex fertilizer. The fertilizer contains macroelements and also contains medium and trace elements subjected to complexing, is high in nutrient utilization rate, diverse in usage manner, wide in usage scope and flexible for trace-element supplement, the ratio of trace elements can be flexibly adjusted according to the soil element lacking status and demands of different crops on trace elements, and the fertilizer is well applicable to soil testing and fertilizer recommendation.

The invention provides a fertilizer synergist and a preparation method thereof. The preparation method comprises the following steps: preparing a porous support through sepiolite powder and cottonseedhull powder; mixing the porous support with tetrasodium iminodisuccinate to obtain a first mixture; then mixing bacillus licheniformis, chaetomium globosum, enterococcus bacillus, hyssutella and humic acid to obtain a second mixture; and finally mixing the first mixture, the second mixture and N-cyclohexylmaleimide, and uniformly pelletizing to obtain the fertilizer synergist. The fertilizer synergist has the effect of synergizing fertilizer.

The invention belongs to the technical field of skin care products, and particularly relates to a slow-release skin-brightening essence composition and a preparation method thereof. The slow-release skin-brightening essence composition is prepared from the following raw materials in percentage by weight: 5-15% of a skin conditioner, 1-10% of an additive and the balance of a solvent. A film-forming agent in the composition can make a penetration enhancer and active ingredients fully play a synergistic role to form a coated penetration structure, continuous penetration can be ensured through combination of various reactants, and the film-forming agent is selected from a trimethylpentanediol/adipic acid copolymer and can ensure the slow release effect of the functional ingredients; and the penetration enhancer used in the composition can enable reactants in the system to form a lipidosome coating structure, and provides a basis for the occurrence of penetration.

The invention relates to the technical field of pesticide fertilizer production, and particularly relates to a slow-release high-tower pesticide fertilizer and a preparation method thereof. Aiming atthe problems existing in the production of the pesticide fertilizer by a high tower method at the present stage, the invention provides the slow-release high-tower pesticide fertilizer, and the slow-release effect is guaranteed through double slow release guarantee of a pesticide and a chemical fertilizer; the activity of the pesticide is ensured by adding carrier powder; and under the action of anitrification inhibitor or a urease inhibitor, the effective utilization rate of the chemical fertilizer is realized, and the growth requirements of crops are met. In addition, the invention also provides a preparation method of the slow-release high-tower pesticide fertilizer. The method is simple and suitable for industrial production.

The present invention relates to a production device and a production method of a double slow release high dispersion medicinal fertilizer; the production device includes a urea solution pipeline, theurea solution pipeline is connected with a granulation system through a third valve, a fourth flow meter, a first inlet and an outlet of a pipeline mixer, the second inlet of the pipeline mixer is connected with a medicinal fertilizer emulsifying device; the medicinal fertilizer emulsifying device includes a pesticide tank which is connected with one side of the top of an emulsifying tank, a solvent tank is connected with the other side of the top of the emulsifying tank, an emulsifying tank motor is arranged at the middle of the top of the emulsifying tank, an emulsifying tank outlet is connected with the inner chamber of a nozzle through a solution pump, the nozzle is arranged on the lower middle part of a fluidized bed reactor, a middle powder inlet of the fluidized bed reactor is connected with a fertilizer carrier tank by a powder pump, a material outlet at the bottom of the fluidized bed reactor is connected with the second inlet of the pipeline mixer, a pesticide can be evenlydistributed inside a fertilizer without direct contact with the fertilizer, the compatibility effect of the pesticide and the fertilizer is overcome, and the purpose of unified double slow release ofthe pesticide and the fertilizer can be achieved.