The invention discloses a dry artificial biological
heart valve containing a
growth factor for promoting endothelialization and a preparation method of the dry artificial biological
heart valve. The method comprises the following steps that cross-linking is performed on amino groups and carboxyl groups of an animal
pericardium, and endothelialization treatment, hydrogel
polymerization treatment and
dewatering and
drying treatment are performed on the animal
pericardium, wherein the endothelialization treatment involves that the
growth factor for promoting the endothelialization is adopted to treat the animal
pericardium. The preparation method has the advantages that the prepared dry biological
heart valve has good
water immersion flattening performance, and can be quickly immersed in water and flattened at a higher temperature and higher
humidity, thereby reducing residues of
glutaraldehyde and the like, and reducing the problems of
calcification and
toxicity which are caused by the
glutaraldehyde and the like, therefore the preoperative installation of a valve
system can be simplified, and the additional risks of surgeries are reduced; the
growth factor capable of promoting the endothelialization is also added in the preparation process, so that the prepared biological valve has the property of promoting the endothelialization.