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64 results about "Paecilomyces cicadae" patented technology

Method for artificially culturing paecilomyces cicadae and application of culturing product thereof

ActiveCN102242070AA Simple Method for Artificially Cultivating Paecilomyces cicadaeReduce manufacturing costCosmetic preparationsSenses disorderSucroseSaccharum
The invention discloses a method for artificially culturing paecilomyces cicadae and application of a culturing product thereof. The method for artificially culturing paecilomyces cicadae in large scales comprises the steps of: preparing strains, dosing and packing into a box, sterilizing, inoculating, solid-fermenting, collecting and the like. The paecilomyces cicadae is cultured by utilizing grains, such as corn flour, bran, wheat, barley, rice, millet, broomcorn and the like and culture mediums of bagasse, cane sugar, shell powder, silkworm chrysalis meal and potassium nitrate. The raw materials are obtained from local resources, a large amount of production cost is saved, the culturing period is shortened, and cordyceps sobolifera obtained by culturing has the advantages of high quality and favorable stability and the like. A culture obtained by the invention can be used for preparing foods, health-care products, drugs and cosmetics with functions of fighting tumor, regulating immunity, reducing blood sugar, blood fat and blood pressure, improving eye sight, resisting radiation, dispelling heat and easing pains, calming and hypnotizing, nourishing and strengthening, improving kidney function and the like.
Owner:ZHEJIANG BIOASIA PHARMA CO LTD

Cordyceps cicadae wine and preparation method thereof

The invention discloses cordyceps cicadae wine and a preparation method thereof. The cordyceps cicadae wine is obtained by dipping coremium of paecilomyces cicadae and / or mycoplasma, as raw materials, in base wine, or obtained by mixing an extract of the coremium of paecilomyces cicadae and / or an extract of mycoplasma, as raw materials, with drinking wine. In the cordyceps cicadae wine, the raw materials are fully utilized, activated secondary metabolism components in the mycoplasma are effectively kept, the integrity of active components in the cordyceps cicadae wine is ensured, the product quality is stable and the production cost is low.
Owner:ZHEJIANG BIOASIA PHARMA CO LTD

Method for improving yield and product activity of liquid fermentation product of Paecilomyces cicadae

The invention discloses a method for improving the yield and product activity of a liquid fermentation product of Paecilomyces cicadae, which comprises the following steps: (1) extracting traditional Chinese medicinal materials composed of 10-40 parts by weight of coix seed, 10-40 parts by weight of radix astragali, 10-40 parts by weight of Chinese wolfberry and 10-40 parts by weight of rhizoma atractylodis macrocephalae through a water solution, thus obtaining a traditional Chinese medicine compound water extract liquid; (2) adding the traditional Chinese medicine compound water extract liquid prepared in the step (1), rhizoma atractylodis macrocephalae lactone and Tween-80 into a fermentation basal culture medium, thus obtaining a Paecilomyces cicadae fermentation culture medium; and (3) inoculating a Paecilomyces cicadae strain into the Paecilomyces cicadae fermentation culture medium prepared in the step (2), performing liquid fermentation to obtain a fermentation liquid, and separating to obtain a fermentation product. According to the invention, particular kinds of traditional Chinese medicine compound water extract liquid, rhizoma atractylodis macrocephalae lactone and Tween-80 are added, so that the biomass and polysaccharide yield of the Paecilomyces cicadae can be obviously improved, and meanwhile, the activity of the polysaccharide is also improved obviously.
Owner:浙江好溢笙生物科技有限公司

Paecilomyces cicadae biological bacteria preparation, method for producing same and application of same to plant nematode prevention

InactiveCN101518265AEliminate yield lossHighly contagiousBiocideFungiPlant nematodeBiotechnology
The invention relates to a method for producing a preparation with biological bacteria, which is used for preventing plant nematodes and the application of the preparation, in particular to a paecilomyces cicadae biological bacteria preparation, a method for producing the same and the application of the same to plant nematode prevention. The paecilomyces cicadae biological bacteria preparation can be the compound of paecilomyces cicadae, culture medium of the paecilomyces cicadae, auxiliary materials and a carrier and is produced by culturing paecilomyces cicadae, fermenting the paecilomyces cicadae with liquid, propagating the paecilomyces cicadae in great qualities, directly processing the paecilomyces cicadae and absorbing the paecilomyces cicadae with the auxiliary materials and the carrier. The paecilomyces cicadae biological bacteria preparation has obvious effect on plant nematode prevention, stable performance and wide application range, reaches the standard of the quality guarantee period of biological pesticide, meets the production requirements of organic food and green food, is environmental friendly, beneficial to human health and prone to large-scale industrial production and serves as broad-spectrum biological bacteria preparation for preventing plant nematodes.
Owner:刘伟平

Medium for producing Paecilomyces cicadae spore, culture method thereof, culture product thereof and application thereof

The invention belongs to the technical field of microbial fermentation, and specifically relates to media for producing Paecilomyces cicadae conidiospores, a culture method thereof, a culture product thereof and application thereof. The media for producing Paecilomyces cicadae conidiospores comprise a solid medium and a liquid medium. The culture method provided in the invention can produce considerable Paecilomyces cicadae conidiospores; the culture product of the method comprises components like polysaccharides, cordycepic acid, adenosine, triterpenoids and a plurality of amino acids, has the functions of regulating immunity, relieving fever and pain, improving renal function, lowering blood pressure, resisting radiation and tumor, reducing blood sugar, etc., and is applicable to the field of human healthy life; considerable spores are generated in the process of fermentation and the generated spores can be used as effective means of biological control, thereby solving the problem that the amount pesticide residues in agricultural products exceed the standard amount from the head stream.
Owner:ZHEJIANG BIOASIA PHARMA CO LTD

Production method of nutritious fungus feed addictive

The invention relates to the production method of paecilomyces cicadae new nutritious fungus feed addictive. The strain used in the method is traditional chinese herbal medicine paecilomyces cicadae. The process includes production processes such as acquisition of strain, cultivation of slant strains and liquid seeds, liquid fermentation, cultivation of solid substrate and so on. The result of animal test indicates that the fungus feed addictive can not only improve the feed conversion rate, save cost, gain meat animals' weight more quickly, reduce the cost by way of improving animal's immunological competence and survival rate with few medicine or no medicine, but also can achieve good effect on weight gains with little quantity of addictive. The production of the fungus feed addictive has advantages of wide raw material sources, easy production, low cost, controllable quality, convenient use, wide application, good actual effect and so on.
Owner:合肥迈可罗生物工程有限公司

Method for separating and purifying paecilomyces cicadae polysaccharide

This invention discloses a method for separating and purifying polysaccharides from Paecilomyces cicadae. The method comprises: extracting polysaccharides from Paecilomyces cicadae by water extraction and alcohol precipitation, purifying by anion exchange column chromatography and gel filtration chromatography, and freeze-drying the extract in vacuum to obtain polysaccharides from Paecilomyces cicadae. The method can retain the bioactivity of natural polysaccharides without influence on the structure, and has low requirement for apparatus and environment. Besides, the method also has such advantages as simple process, and high practicability.
Owner:WENZHOU MEDICAL UNIV

Process for extracting N6-(2-ethoxyl) adenosine from Paecilomyces Cicadae Samson culture

The inventin is named a method for extraction of N6-(2-hydroxyethyl) adenosine from paecilomyces cicadae culture. The invention consists of seperating and breeding new bacterial strain APC-20 of paecilomyces cicadae which is of strong livabitity, high yield of metabolically active compound and good quality from the nature; presenting a method for industrialized solid culture, fluid culture or fermentation production; then eatracting analgesic compounds contained in the said fermented product with 0.36 % of extraction rate and every significant part and providing a method for preparing polytypic species of analgesic drug; the compound has 99 % of analgesic rate examined by little white mouse-twist method. The analgesic mechanism of this compound is different from the presently used opium analgesic agent, and is of no addiction and safe, so it has a broad development and application propect.
Owner:ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES

Rapid liquid submerged fermentation method for producing paecilomyces cicadae powder

The invention discloses a rapid liquid submerged fermentation method for producing paecilomyces cicadae powder. According to the method, paecilomyces cicadae strains are adopted, then a semi-continuous fermentation technology is used to rapidly produce fermentation broth containing a large amount of mycelia, and finally the fermentation broth is separated by a micro filtration membrane to obtain mycelia of paecilomyces cicadae. The conventional paecilomyces cicadae intermittent batch fermentation technology is changed, and at the same time, the mycelia are separated by a high efficient ceramic micro-filtration membrane to replace the conventional centrifugal separation. The shortages of conventional batch fermentation technology such as a lot of steps, long time period between steps, low equipment efficiency, and the like are overcome by semi-continuous fermentation technology. Moreover, a high efficient ceramic membrane is used to filter fermentation broth to reduce the mycelia that enter the filtrate, the yield of mycelia is improved, the COD of filtrate is reduced, thus the processing amount of sewage is reduced, the cells are not obstructed, and effective components in cells can be completely recovered therefore. Compared with the conventional method, the provided method can generate prominent economic benefit, social benefit, and environmental benefit.
Owner:JIANGSU SHENHUA PHARMA

Protease gene obtained from paecilomyces cicadae and having function of degrading insect body wall and application

The invention discloses protease gene obtained from paecilomyces cicadae and having a function of degrading an insect body wall, wherein the protease gene is shown in SEQ IN NO: 16; and a protease protein fragment which is obtained from the paecilomyces cicadae and has the function of degrading the insect body wall is provided, wherein the amino acid sequence of the protease is shown in SEQ IN NO: 17. By utilizing the protease gene disclosed by the invention and expressed by genes, the insect body wall can be degraded, and a new idea is provided and a new manner is created for the research on a novel, high-efficiency and safe pesticide.
Owner:ZHEJIANG SUB TROPICS CROP INST

Artificial cultivation method of cordyceps sobolifera

The invention discloses an artificial cultivation method of cordyceps sobolifera. The method comprises the following steps: soaking mature nymphs of cicadas obtained by either field acquisition or artificial cultivation with pure water for 5 min, washing, and drying on a filter screen; uniformly spraying paecilomyces cicadae strain diluted solution, of which the total active bacteria number is 1*108, obtained by the culture and expanding propagation in a culture chamber, to the dried nymphs by a sprayer according to 5% of the weight of the nymphs; moving the re-dried nymphs into a cordyceps sobolifera cultivation plate, covering a plate cover, and cultivating in a sterile room at the temperature of 24-26 DEG C and the relative air humidity of 80-90%; after the heads of the nymphs grow cordyceps sobolifera which is similar to flowers, and taking out and drying the cordyceps sobolifera to obtain the artificially cultivated cordyceps sobolifera. Meanwhile, the invention discloses a cultivation plate for artificially cultivating the cordyceps sobolifera; in addition, by adopting the artificial cultivation method of cordyceps sobolifera to cultivate the cordyceps sobolifera, the industrial production of the cordyceps sobolifera can be realized, and the increasingly grown dietary therapy and clinical demands can be met.
Owner:XUZHOU LIANGHAN AGRI DEV CO LTD

Penicillium paecilomyces cicadae (miquel) samson fermentation product used as feed additive as well as preparation method and application thereof

The invention discloses a feed additive which is the penicillium paecilomyces cicadae (miquel) samson fermentation product. The invention further discloses a preparation method and application of the feed additive. The preparation process of the feed additive is simple, the raw materials for preparing the feed additive are easy to obtain, and the feed additive is rich in adenosine, cordycepic acid and polysaccharides. Though a little feed additive is added to the animal feed, the feed additive can achieve a significant effect. The feed additive can improve the utilization rate of the feed, improve the palatability of the animals, promote the growth and the development of the animals, improve the quality of the livestock and poultry feed and use the feed resources more reasonably. In addition, the feed additives can strength the immune regulation of the animals to improve the survival rate of the animals so that the animal feeding cost is reduced.
Owner:ZHEJIANG BIOASIA PHARMA CO LTD

Application of fermentation product of paecilomyces cicadae

The invention belongs to the technical field of microbial fermentation, and specifically relates to media for producing Paecilomyces cicadae conidiospores, a culture method thereof, a culture product thereof and application thereof. The media for producing Paecilomyces cicadae conidiospores comprise a solid medium and a liquid medium. The culture method provided in the invention can produce considerable Paecilomyces cicadae conidiospores; the culture product of the method comprises components like polysaccharides, cordycepic acid, adenosine, triterpenoids and a plurality of amino acids, has the functions of regulating immunity, relieving fever and pain, improving renal function, lowering blood pressure, resisting radiation and tumor, reducing blood sugar, etc., and is applicable to the field of human healthy life; considerable spores are generated in the process of fermentation and the generated spores can be used as effective means of biological control, thereby solving the problem that the amount pesticide residues in agricultural products exceed the standard amount from the head stream.
Owner:ZHEJIANG BIOASIA PHARMA CO LTD

Culture method of selenium-enriched cordyceps sobolifera conidial powder

The invention discloses a culture method of selenium-enriched cordyceps sobolifera conidial powder. Firstly, separation, purification and identification are performed on cordyceps sobolifera collected in a field to obtain Paecilomyces cicadae (Miquel.) Samson, plate cultivation is performed to obtain single colonies, then, the single colonies are transferred to a liquid medium for culture, a liquid secondary seed solution is obtained, the secondary seed solution is transferred to a composite culture medium containing organic selenium fertilizer, the temperature is controlled to 15-35 DEG C, the humidity is controlled to 60-90%, ventilation culture is performed for 4-6 weeks, and harvesting is performed to obtain selenium-enriched cordyceps sobolifera conidial powder. Artificial simulation is performed to obtain nutritional and growth conditions closest to the conditions needed by cordyceps sobolifera wild environment, growth of cordyceps sobolifera is not limited by season changes, the composite culture medium is closer to natural bamboo forest cordyceps sobolifera wild environment, the breathability is good, the water absorption and moisturizing performance are excellent, a fruiting body grows rapidly, spore head and conidial powder of the fruiting body are abundant, thick, solid, full, large in conidial powder amount, high in quality and easy to harvest, the content of selenium is 20-100 mg / Kg, the method is simple and low in cost, the spore harvesting period is short, and industrial production can be achieved.
Owner:SUN YAT SEN UNIV

Fermentation method of antioxidant cordyceps sobolifera mycelia

The invention provides a fermentation method of antioxidant cordyceps sobolifera mycelia. The fermentation method comprises the following steps: respectively preparing a PDA slant culture medium, a seed culture solution and a fermentation culture medium; dividing the paecilomyces cicadae mother strain through sterile operation, and inoculating the paecilomyces cicadae mother strain to the PDA slant culture medium for activation culture to obtain an activated strain; inoculating the activated strain into a seed culture solution to obtain a primary strain; inoculating the primary strain into theseed culture solution, and culturing the primary strain according to a method for culturing the activated strain to obtain a secondary strain; inoculating the primary strain or the secondary strain into the seed culture solution for culturing to obtain a fermentation tank seed solution; inoculating the fermentation tank seed solution into the fermentation culture medium, and carrying out fermentation culture to obtain cordyceps sobolifera fermentation liquor; and discharging the cordyceps sobolifera fermentation liquor, and carrying out semi-solid fermentation culture to obtain the fermentation product of the antioxidant cordyceps sobolifera mycelia. The fermentation method is suitable for fermentation production of cordyceps sobolifera mycelia, the obtained mycelia is high in biomass andstrong in antioxidant activity, the yield of active substance polysaccharide and cordycepic acid can be remarkably increased, and the source of health-care food raw materials is increased.
Owner:JIANGSU POLYTECHNIC COLLEGE OF AGRI & FORESTRY

Paecilomyces cicadae and application

The invention discloses paecilomyces cicadae and application in preparing an antibacterial agent, a probiotic preparation and an antibacterial fresh-keeping film. A novel strain-paecilomyces cicadae CH 113.1 is first separated from field entomogenous fungus cordyceps sobolifera. A strain fermentation product has an inhibition effect for conventional pathogenic microorganisms, the inhibition rate for the escherichia coli can reach 70 percent or more, and the biological bacteriostatic agent can be applied to the fresh keeping of food. The strain has a good application prospect in the field of food.
Owner:HANGZHOU NORMAL UNIVERSITY

Paecilomyces cicadae fermentation culture medium and method for preparing ergosterol by paecilomyces cicadae fermentation

The invention provides a pecilomyces cicadae fermentation culture medium and a method for preparing ergosterol by the paecilomyces cicadae fermentation, wherein raw material components of the paecilomyces cicadae fermentation culture medium comprise bamboo shoot heads, potassium dihydrogen phosphate, ferrous sulfate and magnesium sulfate. The paecilomyces cicadae fermentation culture medium can beused as a fermentation culture medium for preparing ergosterol by paecilomyces cicadae; meanwhile, the paecilomyces cicadae fermentation culture medium takes the bamboo shoot heads as main raw materials, can reasonably utilize the bamboo shoot head resources, solves the problem of resource waste and environmental pollution caused by the fact that most of bamboo shoot head residues after eating orprocessing are discarded randomly or simply buried, has potential economic value and wide market prospect.
Owner:FUJIAN INST OF MICROBIOLOGY

Identification method for paecilomyces cicadae strain

The invention relates to the technical field of molecular biology, and discloses a method for identifying a paecilomyces cicadae strain CGMCC No. 3453. The method comprises the following steps of: extracting DNA (Deoxyribonucleic Acid) of the strain to be detected; performing PCR (Polymerase Chain Reaction) amplification on the DNA of the strain to be detected by using primers S6, S10, S31, OPV-14 and OPW-06 respectively; performing agarose gel electrophoresis on the obtained amplification products respectively to obtain an RAPD (Random Amplified Polymorphic DNA) band graph of the strain to be detected; and comparing the obtained RAPD band graph of the strain to be detected with the RAPD band graph of a standard sample and judging to obtain an identification result. By using the identification method provided by the invention, the paecilomyces cicadae strain CGMCC No. 3453 can be quickly and accurately identified without being affected by environment.
Owner:ZHEJIANG BIOASIA PHARMA CO LTD

Method for producing hovenia acerba fruit vinegar

The invention belongs to the field of technologies for making fruit vinegar, and provides a method for producing hovenia acerba fruit vinegar.The method includes steps of pulping raw materials; sterilizing the raw materials; fermenting paecilomyces cicadae; fermenting alcohol; fermenting acetic acid; spraying and filtering vinegar; canning and sterilizing the vinegar.Compared with existing methods for making table vinegar, the method for producing the hovenia acerba fruit vinegar has the advantages that the alcohol fermentation liquor yield can be increased by 10-15% as compared with the liquor yields of the traditional methods for making the table vinegar, and the hovenia acerba fruit vinegar yield can be increased by 10-15%; chemical preservatives for the hovenia acerba fruit vinegar can be omitted owing to antibacterial oligopeptide of certain antibacterial components produced in paecilomyces cicadae fermentation procedures by means of metabolism, and the hovenia acerba fruit vinegar has good flavor and tastes delicious.
Owner:SHAANXI ZHENDING IND

A method for increasing the yield and activity of Paecilomyces cicadae liquid fermentation product

The invention discloses a method for improving the yield and product activity of a liquid fermentation product of Paecilomyces cicadae, which comprises the following steps: (1) extracting traditional Chinese medicinal materials composed of 10-40 parts by weight of coix seed, 10-40 parts by weight of radix astragali, 10-40 parts by weight of Chinese wolfberry and 10-40 parts by weight of rhizoma atractylodis macrocephalae through a water solution, thus obtaining a traditional Chinese medicine compound water extract liquid; (2) adding the traditional Chinese medicine compound water extract liquid prepared in the step (1), rhizoma atractylodis macrocephalae lactone and Tween-80 into a fermentation basal culture medium, thus obtaining a Paecilomyces cicadae fermentation culture medium; and (3) inoculating a Paecilomyces cicadae strain into the Paecilomyces cicadae fermentation culture medium prepared in the step (2), performing liquid fermentation to obtain a fermentation liquid, and separating to obtain a fermentation product. According to the invention, particular kinds of traditional Chinese medicine compound water extract liquid, rhizoma atractylodis macrocephalae lactone and Tween-80 are added, so that the biomass and polysaccharide yield of the Paecilomyces cicadae can be obviously improved, and meanwhile, the activity of the polysaccharide is also improved obviously.
Owner:浙江好溢笙生物科技有限公司

Efficient cultivation method of isaria cicadae miq

The invention provides an efficient cultivation method of isaria cicadae miq, which comprises the following steps of: 1) selecting an olive tree orchard with sandy soil, intercropping gynostemma pentaphyllum under olive trees, soaking the egg branches of the isaria cicadae miq in weak acid electrolyzed water and airing under the sun, then transferring the egg branches of the isaria cicadae miq toa heat preservation room, controlling the humidity of the heat preservation room to be 70-8% and the temperature to be 30-35 DEG C, spraying the egg branches once every day by using balsam pear juiceat 6.00 p. m. until golden cicada is hatched and put into the orchard for cultivation; 2) carrying out weeding and insect prevention and topdressing on the gynostemma pentaphylla during the cultivation period of the golden cicada; 3) putting the golden cicada into a cultivation chamber after killing the golden cicada, controlling the oxygen partial pressure, temperature and humidity in the cultivation chamber, and continuously cultivating to obtain the isaria cicadae miq. The method has the advantages of high hatching rate of the golden cicada eggs, and promotion of the transformation of paecilomyces cicadae from a nutrient stage to a sexual stage and the like.
Owner:广西南宁秀珀生物科技有限公司

Astragalus membranaceus-paecilomyces cicadae fermented fungal substance, preparation method and application

ActiveCN110656130AIncrease productionIncreased total polysaccharide contentMetabolism disorderMicroorganismsBiotechnologyPectinase
The invention discloses astragalus membranaceus-paecilomyces cicadae fermented fungal substance and a preparation method and application thereof. The fermented fungal substance is prepared by liquid fermentation by taking an enzymatic hydrolysate of astragalus membranaceus as a fermentation substrate and paecilomyces cicadae as a fermentation strain; wherein the enzymatic hydrolysate of astragalusmembranaceus is obtained by enzymatic hydrolysis of astragalus membranaceus through cellulase and pectinase. The astragalus membranaceus-paecilomyces cicadae fermented fungal substance has significantly increased astragalus polysaccharide content, and has significant effects in treating hyperuricemia and / or hypertriglyceridemia.
Owner:BINZHOU MEDICAL COLLEGE

Liquid medium for producing plasmin by utilizing cordyceps sobolifera and plasmin production method thereof

The invention discloses a liquid medium for producing plasmin by utilizing cordyceps sobolifera and a plasmin production method thereof and belongs to the technical field of microbes. The liquid medium comprises the following active ingredients in parts by weight: 8-15 parts of tryptone, 30 parts of glucose, 1 part of monopotassium phosphate, 3 parts of yeast extract, 0.2 part of magnesium sulfate heptahydrate and 1000 parts of water. The method for producing plasmin by utilizing the liquid medium for producing plasmin by utilizing cordyceps sobolifera comprises the following steps of: (1) inoculating a paecilomyces cicadae strain (B5) onto a PDA panel with the diameter of 9cm, and culturing at the temperature of 25 DEG C for 5 days; (2) filling 200mL of the prepared liquid medium into a 500mL triangular flask, sterilizing at the temperature of 121 DEG C for 20 minutes, cooling to room temperature, teasing a piece of 3*3mm<2> hypha by using a teasing needle, inoculating to the prepared liquid induced medium panel, and culturing on a shaker at the temperature of 25 DEG C for 6-15 days; and (3) performing high-speed centrifugal separation on the culture solution at a speed of 10000 revolutions per minute for 5 minutes, and taking the supernatant as plasmin crude extract for later use.
Owner:李伟

Radix astragali-penicillium cicada fermentation bacterium and application thereof

The invention discloses a radix astragali-penicillium cicada fermentation bacterium and application thereof. The fermentation bacterium is prepared from medicinal radix astragali powder as a fermentation substrate and penicillium cicada as a fermentation bacterium through solid fermentation. The radix astragali-penicillium cicada fermentation bacterium disclosed by the invention has a remarkable function of treating hyperuricemia and hypertriglyceridemia.
Owner:BINZHOU MEDICAL COLLEGE

Cultivation method for imitative wild Cordyceps cicadae

The invention discloses a cultivating method for imitative wild Cordyceps cicadae, comprising the following steps of: 1) an olive tree orchard with sandy soil was selected, gynostemma pentaphyllum isintercropped under the olive trees, small branches with cicada eggs are soaked in weak acid electrolyzed water and dried in the sun, and the cicadas are incubated for breeding; 2) weeding, preventinginsects and top-dressing are conducted for gynostemma pentaphyllum on a regular basis during the breeding period of the cicadas; 1) by laying a layer of sandy soil with a humidity of 40-50% in the culture room, the artificially collected cicadas are killed with ozone and dried till the humidity is 60-80% of the initial stage, then the dried cicadas are sprayed and cultured to Paecilomyces cicadaeof the exponential growth phase and transferred to the culture room to bury for 4-6 cm deep in sandy soil. By controlling the oxygen partial pressure, temperature and humidity in the culture room, thecicadas are continuously cultured till the Cordyceps cicadae is obtained. The method has the characteristics of high hatching rate of cicada eggs and promoting the transformation of Paecilomyces cicadae from vegetative stage to sexual stage.
Owner:广西南宁秀珀生物科技有限公司

Medicinal liquor with efficacies of tonifying the liver and kidney

The invention discloses a medicinal liquor with efficacies of tonifying the liver and kidney. The medicinal liquor is characterized by comprising the following ingredients: 15 grams of fructus psoraleae, 3 grams of Ligusticum wallichii, 5 grams of Paecilomyces cicadae, 10 grams of chrysanthemum, 6 grams of fruit of Chinese wolfberry, 5 grams of white quartz, 3 grams of Amomum cardamomum, 15 grams of cinnamon, 3 grams of Poria cocos and poria with hostwood, 10 grams of fructus viticis, 10 grams of honey and 800 ml of liquor with alcoholic strength of 40%. The composition of the formula of the invention can play a synergistic effect, and can specifically play the effects of invigorating the kidney, replenishing essence, nourishing blood, activating meridians, and is applicable to the treatment of fatigue caused by insufficient essence and blood; and the medicinal liquor has the advanategs of simple production, obvious effect, low cost and benefit for the body health of people.
Owner:洪艳平

House lizard/Paecilomyces cicadae bidirectional solid ferment and preparation method and application thereof

ActiveCN109966322AImprove anti-tumor functionExpand the way of medicineUnknown materialsAntineoplastic agentsPenicillium bilaiaeMedicine
The invention belongs to the technical field of traditional Chinese medicine preparations and particularly relates to a house lizard / Paecilomyces cicadae bidirectional solid ferment and further discloses a preparation method thereof and application of the house lizard / Paecilomyces cicadae bidirectional solid ferment in the preparation of liver cancer drugs. The house lizard / Paecilomyces cicadae bidirectional solid ferment is made by further fermenting a Paecilomyces cicadae liquid based on existing house lizard medicinal material; with unique properties and functional components of the house lizard and Paecilomyces cicadae, the antitumor function of the house lizard medicinal material is improved through deep interaction of the house lizard and Paecilomyces cicadae. The effective components of the house lizard / Paecilomyces cicadae bidirectional solid ferment are acquired by water extraction; the water extract can inhibit HepG2 liver cancer cells significantly and is suitable for the preparation of liver cancer drugs.
Owner:经皮永和医药科技(北京)有限公司

Yaochi camellia nitidissima

The present invention discloses yaochi camellia nitidissima. A raw material formula of the yaochi camellia nitidissima comprises the following raw materials in mass ratios: 0.5g-1g of camellia nitidissima, 0.5g-1g of fructus momordicae, 0.5g-1g of rhizoma alismatis, 0.5g-1g of cornus officinalis, 0.5g-1g of longan pulp, 0.5g-1g of caulis spatholobi, 0.5g-1g of paecilomyces cicadae, 0.5g-1g of cordyceps sinensis,3.5g-4g of Chinese wolfberry fruits, 1.5g-2g of tea stems, 1.5g-2g of momordica grosvenori flowers, 1.5g-2g of radix puerariae, 1.5g-2g of Chinese yams, 1.5g-2g of poria cocos and 1.5g-2g of semen euryales. The prepared yaochi camellia nitidissima has remarkable effects on treating various diseases such as hyperlipidemia, hypertension, hypotension, diabetes, stomach illness, kidneydeficiency, arthritis, urogenital inflammation, kidney and urinary calculus, constipation, etc., the various raw materials are mixed, stirred and crushed into the yaochi camellia nitidissima, medicinal properties of the camellia nitidissima can be improved, manufacture processes are simple, the manufacturing cost is reduced, and production efficiency is improved.
Owner:苏州瑶池生物科技有限公司
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