65 results about "Houttuynin" patented technology

The present invention relates to a freeze-dried composition of new houttuynin sodium. It includes new houttuynin sodium with therapeutic effective dose and additive agent which can be freeze-dried, in which the dose of new houttuynin sodium is 0.05-0.5% of prescription solution dose, and the additive agent which can be freeze-dried includes tween-80 and dilutent agent, in which the dose of tween-80 is 0.5-2.5 % of prescription solution dose, and the dilutent agent is one kind selected from mannitol, lactose, dextran, dextrose, amino acetic acid, hydrolysed gelatin and polyvidone, etc. or mixture of them. Said invention also provides its preparation process and concrete steps.

The invention relates to the technical field of attractants, in particular to fly attractant. The fly attractant is prepared from, by weight, 2-3 parts of fish oil, 1-2 parts of houttuynin, 1.5-3 parts of fly maggot powder, 2-2.4 parts of shrimp meal, 3-4 parts of rose oxide, 30-35 parts of composite yeast, 20-25 parts of white sugar, 10-15 parts of brown sugar, 3-4 parts of malt sugar, 3-4 parts of fish bone meal, 1-3 parts of ionone, 0.8-1 part of 4-methoxybenzaldehyde, 0.1-0.5 part of cis-3-hexenal, 1-3 parts of 1-ethylhexenol, 5-7 parts of lard oil, 0.3-0.4 part of sunset yellow, 0.1-0.3 part of 2,6-di-tert-butyl-4-methyl phenol and 0.5-1 part of calcium carbonate. The fly attractant has a strong attracting effect on flies, and is free of toxicity, easy to use and is non-toxic to people and livestock, the preparation method is simple, the production cost is low, and the effect is durable.

The invention discloses a preparation technology of a high-content compound herba houttuyniae mixture. According to the invention, herba houttuyniae, radix scutellariae, radix isatidis, fructus forsythia and honeysuckle are used as main medicinal materials to prepare the high-content compound herba houttuyniae mixture. The mixture contains the following active medicinal components: 10-25 micrograms / ml of houttuynin, 50-100 micrograms / ml of quercitrin, 1-2 mg / ml of baicalin and 15-40 micrograms / ml of forsythin. The preparation technology comprises the following steps: (1) flash extraction; (2) steam distillation; (3) alcohol precipitation; (4) water precipitation; and (5) preparation of the mixture. By the preparation technology, contents of the active medicinal components such as houttuynin, quercitrin and the like in the compound herba houttuyniae mixture can be effectively increased. In addition, components such as polysaccharide, protein, tannin and the like in the medicinal materials can be removed. Thus, precipitates generated during selling and storing process are reduced, and stability and safety of the medicine are raised. Besides, the high-content compound herba houttuyniae mixture can effectively treat throat pain caused by wind-heat common cold and acute pharyngitis and tonsillitis if used separately.

The present invention relates to one kind of houttuynin sodium powder for injection and its preparation. The houttuynin sodium powder for injection contains houttuynin sodium in 1-10 wt%, solubilizer in 20-40 wt% and excipient in 50-70 wt%. The houttuynin sodium powder for injection may be stored for long term without degradation and other chemical change, and the present invention solves the problem of houttuynin sodium in shelf stability.

A sodium neohouttuyfonate injection for treating adnexitis, pelvic inflammation, chronic cervicitis, upper respiratory tract infection, chronic bronchitis, pneumonia, etc is prepared from sodium neohouttuyfonate, tween-80 sodium hydrogen sulfite and the water for injection. Its preparing process is also disclosed.

A Chinese medicine in the form of injection of any orally taken form for treating the infection of respiratory tract and digestive system, improving immunity, and preventing tumor is proportionally prepared from Asiatic moonseed rhizome or its extract and the sodium neohouttuyfonate or its pharmacologically acceptable salt.

The invention discloses the preparation method of sodium new neohouttuyfonate injection. The preparation comprises sodium new neohouttuyfonate, tween-80, sodium hydrosulfite and water for injection. In the invention, the sodium new neohouttuyfonate and 1-40 times the amount of tween-80 are fully ground uniformly and dissolved with the water for injection so as to ensure that the sodium new neohouttuyfonate can be fully dissolved into the water for injection and does not separate out during the preparing and filtering process; and meanwhile, the sodium hydrosulfite is added to prevent the sodium new neohouttuyfonate from being oxidized and degraded during the process flow. The sodium new neohouttuyfonate injection is used for treating various inflammations of digestive tract, pneogaster and urinary organs and can also be used for treating upper respiratory tract infection, chronic bronchitis, pulmonitis, and the like.

The present invention relates to the technical field of attractants, in particular to fly attractants, which are composed of the following components in parts by weight: 2-3 parts of fish oil, 1-2 parts of fishantin, 1.5-3 parts of fly maggot powder, and 2-3 parts of shrimp powder. 2.4 parts, 3-4 parts of baitene, 30-35 parts of compound fermented product, 20-25 parts of white sugar, 10-15 parts of brown sugar, 3-4 parts of maltose, 3-4 parts of fish bone meal, dodecylbenzenesulfonate 1-3 parts of sodium bicarbonate, 0.8-1 part of 4-methoxybenzaldehyde, 0.1-0.5 parts of cis-3-hexenal, 1-3 parts of 1-octenol, 5-7 parts of lard, sunset yellow 0.3-0.4 parts, 0.1-0.3 parts of 2,6-di-tert-butyl-4-methylphenol, 0.5-1 part of calcium carbonate. The fly attractant provided by the invention has strong luring effect on flies, is non-toxic, easy to use, non-toxic to humans and animals, has simple preparation method, low production cost and long-lasting effect.

The present invention relates to local use medicine preparation containing antiinfective medicine composition, and features that the antiinfective medicine composition includes houttuynin or houttuynin sodium and chlorgenic acid in the weight ratio of 1 / 3 to 10 and is prepared into eye drop or eye gel. The present invention has the advantages of high antibacterial effect, high curative effect, local use, fast acting and use convenience.

A sodium neohouttuyfonate injection is prepared through dissolving hydroxypropyl-beta-dextrin in the water for injection, adding sodium neohouttuyfonate, stirring or grinding, and preparing injection liquid or (vacuum or freeze or spray) drying to obtain powdered injection.

The invention belongs to the technical field of biological engineering, and particularly relates to a mosquito sustained-release attractant and a preparation method thereof. The preparation method comprises steps as follows: rose oxide, (1R,2R,8aS)-decahydro-1-(3-hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyl-2-naphthol and ionone are dissolved in ethanol, and a solution is formed; the solution is added to 30-40 parts of mannitol, and paste is obtained; glucose, fish oil, houttuynin, shrimp meal, wheat bran, rape seed cakes, lard oil, 2,6-ditert-butyl-4-methylphenol and a plant fermentation product are uniformly mixed with the paste, and the mosquito sustained-release attractant is obtained. According to the mosquito sustained-release attractant and the preparation method thereof, environmental friendly materials such as the fermented plant, houttuynin and the like are utilized as main materials, the preparation method is simple, the mosquito sustained-release attractant is non-toxic and safe to use and has very strong attracting performance on mosquitoes, and the effect is long-lasting.

The invention discloses an antibacterial outer shell used for an automotive electronic igniter. The outer shell comprises the following raw materials in parts by weight: 125-135 parts of a main material, 1-2 parts of isopropyl tri(dioctylpyrophosphate) titanate, 0.5-1.2 parts of maleic anhydride, 1-5 parts of a composite antibacterial agent, 5-10 parts of precipitated barium sulfate, 2-6 parts ofheavy calcium carbonate, 1-6 parts of calcined kaolin, 2-4 parts of graphene, 1-2 parts of trimethylethoxysilane, 2-4 parts of a dispersant, 1-2 parts of an anti-aging agent, and 1-2 parts of a defoaming agent, wherein the composite antibacterial agent is prepared by the following processes: performing uniform mixing on houttuynin and toluene, adding a hydrogen peroxide aqueous solution dropwise,raising the temperature, performing stirring, performing extraction by adopting dichloromethane, collecting an organic phase, performing evaporation to dryness, adding nano zinc oxide, nano silver oxide, sepiolite powder and water, performing mixing, raising the temperature, performing stirring, raising the temperature, continuing stirring, performing cooling, performing filtering, performing washing, and performing drying to obtain the composite antibacterial agent.

The invention relates to a method for preparing the traditional solid medicine, which uses the saikoside, baicalin and houttuynine sodium bisulfite sodium at different mass percentages, to build technical checking method and solubility testing method, via antiviral tests to select the best combination, and uses the solubility test to find the preparation.

A fatty emulsion with high stability and synergistic function contains houttuyninum analog, plant oil, phasphatide and the water for injection.

The invention discloses mouthwash for pregnant women and a preparation method of the mouthwash. The mouthwash is prepared from the following components in percentage by weight: 0.01%-0.02% of taxifolin, 0.01%-0.1% of houttuynin, 0.01%-0.1% of bamboo vinegar, 0.1%-0.2% of common sage herb extract, 0.1%-0.5% of mangosteen extract, 0.2%-0.5% of essence, 1%-3% of cocamidopropyl betaine, 1%-15% of aloe vera gel, 2%-5% of xylitol and the balance of water. The preparation methodof the mouthwash comprises the following steps: weighing the components according to the content, and dissolving the taxifolin and the houttuynin with a small amount of edible ethanol to obtain a solution A; adding the bamboo vinegar, the common sage herb extract, the mangosteen extract, the essence, the cocamidopropyl betaine, the aloe vera gel and the xylitol to water to obtain a solution B, mixing thesolution A with the solution B, putting the mixed solution in pasteurization equipment for sterilization and performing filling to obtain the mouthwash. The mouthwash is designed for the pregnant women, contains no toxic substances or preservatives, cannot harm growth and development of mothers' bodies and infants and has effects of cleaning the mouth, removing odor, resisting and killing bacteria, preventing oral disease and enhancing the oral skin resistance.

The invention relates to a sodium new houttuyfonate pharmaceutical composition for treating respiratory tract infection and process for preparation, wherein the pharmaceutical composition comprises sodium new houttuyninum, Poloxamer or Tween-80, the preparing process comprises dissolving Poloxamer or Tween-80 into water, charging sodium hydrogen sulfite to adjust PH to 1.5-8.5, charging sodium new houttuyninum, mixing and charging excipient, isotonic agent. The dosages types include small liquid drug injections, freeze-dried powder injections, asepsis split charged powder injections, high capacity injections or fluid infusions.

The invention discloses the preparing method of houttuynia cordata honeysuckle flower injection, comprising the following steps: washing the houttuynia cordata , drying it, weighing it, boiling it, and getting houttuynia cordata extract; boiling the honeysuckle flower, extracting it, and getting honeysuckle flower extract; using the houttuynia cordata extract and honeysuckle flower extract to get injection extract and injection. In the injection, the volatile oil content is lower 0.10%., the houttuyninum content is more than 24.0 mug per mg, which is calculated with C11H22O, and other components meet the fingerprint pattern specified amount.

The invention relates to an essential oil solid crystalline bactericidal agent and a preparation method thereof. The essential oil solid crystalline bactericidal agent is characterized by comprising the following components in parts by weight: 12-15 parts of clove, 7-10 parts of rosemary essential oil, 10-15 parts of Artemisia argyi essential oil, 7-10 parts of lavender essential oil, 7-10 parts of houttuynin, 3-5 parts of baicalin, 5-7 parts of Juncus effuses, 35-45 parts of mildew preventive, 10-15 parts of aromatic liquid and 4-8 parts of essence. The preparation method comprises the following steps: heating other components; adding the heated other components into a mixture of the mildew preventive and the baicalin; evenly stirring; and naturally cooling. The invention has the advantages that the preparation method is simple, the bacteriostatic effect is good, environmental friendliness is ensured, and the cost is low.

The invention discloses a compound preparation which comprises two or more of extracts of baikal skullcap root glycosides, barren wort glycosides, houttuynine sodium bisulfite or houttuyninum, and can be prepared into injections, capsules, tablets, dispersible tablets, sublingual tablets, granules, oral liquid preparations, drop pills and other pharmacologically allowable dose forms. The invention can be applied to the treatment of pneumonia, respiratory tract infection, influenza, avian Influenza, SARS and asthma.

The invention relates to a method for inducing pyroptosis of lung adenocarcinoma NCI-H1299 cells through a traditional Chinese medicine monomer sodium new houttuyfonate, and belongs to the field of traditional Chinese medicine monomer application, sodium new houttuyfonate promotes the lung adenocarcinoma NCI-H1299 cells to release inflammatory factors IL-1beta and IL-18, inflammasome NLRP3 is used as a mediation, and through ASC protein oligomerization, caspase1, IL-1beta and GSDMD protein shearing, the classical path of pyroptosis is activated, thereby conducing pyroptosis of NCI-H1299 cells. The sodium new houttuyfonate can be used for inhibiting tumor growth of a lung adenocarcinoma model mouse caused by NCI-H1299 cells, so that the sodium new houttuyfonate is expected to be used as an active component for preparing the lung adenocarcinoma resisting medicine, and has obvious clinical application value.

The invention discloses a synthetic method of a houttuynin heterozygous flavonoid compound. The method comprises the steps that a compound 1-I reacts with an acetylation reagent; obtained 1-II and 1-undecyne are subjected to a stirring light-resistant reaction under the protection of inert gas; obtained 1-III and alkali are subjected to a stirring reaction at -10-30 DEG C; obtained 1-IV reacts with 1-acetyl-3,5-bis(benzyloxy)phenol; obtained 1-V and iodine and DMSO are subjected to a stirring reaction at 50-150 DEG C; obtained 1-VI reacts with potassium peroxomonosulfate and p-toluene sulfonicacid on the condition that the pH value is 9-12; obtained 1-VII and acid and water are subjected to a stirring reaction at 80-130 DEG C; obtained 1-VIII and brominated sugar are subjected to a stirring reaction; obtained 1-IX takes off a protecting group, and 1-X is obtained; the 1-X reacts with an oxidant, and i-XI is obtained. The method is simple, and the yield is high.

The invention belongs to the field of medicinal preparations and particularly relates to a preparation method of a lipid microsphere preparation of houttuynin and a houttuynin derivative. The lipid microsphere preparation contains the houttuynin or the houttuynin derivative. The preparation takes phospholipid and other surfactants as emulsifiers and takes high-purity plant oil as a solvent. Lipid microspheres are prepared by high-pressure homogenizing equipment. Compared with the conventional houttuynin injection, the lipid microsphere preparation avoids the application of latent solvents such as Tween and the like and remarkably improves the stability of a preparation.

A composite medicine in the form of injection for treating atypical pneumonitis, etc is prepared from medicine Libaweilin 50-2500 mg, sodium neohouttuyfonate 0.25-25 mg and medicinal auxiliary through heating, stirring, filter, and regulating pH value.

A medical composition for preventing and treating infection and viral diseases, antipyressis, and analgesia is prepared from sodium neohouttuyfonate or its pharmacologically acceptable salt (1-20 portions) and scutelloside (30-500 portions). Its preparing process is also disclosed.

The invention discloses a plant material for environmental disinfection and a preparation method of the plant material. The plant material comprises protocatechuic acid, silybum marianum, houttuynia,baicalin, menthol, a sublimating agent, glycyrrhizic acid, an oak moss extract, pine needle oil and myrrh oil. The preparation method comprises the following steps: mixing the silybum marianum and thebaicalin; mixing the protocatechuic acid, the houttuynia, the menthol and the glycyrrhizic acid; mixing the pine needle oil, the myrrh oil and the oak moss extract; mixing all mixtures with the sublimating agent, performing uniform stirring, and performing sealing and packaging, so as to obtain the plant material. The plant material is qualified in multiple tests, is nontoxic, high in efficiency,long lasting in effect, broad in spectrum and good in sublimability, is most effective for influenza viruses in the air, epidemic encephalitis viruses, typhoid fever viruses, escherichia coli, staphylococcus aureus, tritirachium album and legionella, has a remarkable killing effect on more than thirty common molds such as aspergillus flavus, aspergillus fumigates and penicillium citrinum, and inaddition has a remarkable effect on harmful gases such as formaldehyde, benzene and sulfur dioxide which are decomposed in the air.

The invention provides sodium houttuyfonate dispersible tablets. The sodium houttuyfonate dispersible tablets are prepared by uniformly mixing coating micro-capsules of sodium houttuyfonate with other pharmaceutically acceptable adjuvant materials prior to tableting.

The invention discloses a compound allicin soft capsule and a preparation and packaging method thereof. The compound allicin soft capsule is composed of a capsule content and a capsule skin. The capsule content comprises the following components in percentage by mass: allicin: 1%-65% of allicin and 1%-55% of houttuynin; the capsule skin comprises the following components in percentage by mass: 10%-22% of a rubber excipient, 1%-10% of a plasticizer, 1%-10% of an additive and 50%-80% of water. The compound allicin soft capsule has the beneficial effect that the allicin and houttuynin are sully mixed in a certain ratio, so that the effects cooperate with each other, a broad-spectrum antibacterial drug which has exact therapeutic effects, can be taken for a long time and has no toxic or side effects is obtained, meanwhile, the drug components are clear, the action mechanism is explicit, and the defects of complex components of traditional Chinese medicines and unknown pharmacological mechanisms are avoided. In addition, the defects that chemical drugs have large toxic and side effects on the liver and spleen and cannot be taken for a long term are overcome.

The invention discloses an antibacterial glass fiber air filter paper, which is prepared from the following raw materials in parts by weight: 80 to 100 parts of alkali-free glass microfiber, 10 to 15parts of polytetrafluoroethylene, 15 to 20 parts of dimethyl sulfoxide, 3 to 5 parts of houttuynin, 2 to 3 parts of 4-isopropyl-2-hydroxy-cycloheptyl-2,4,6-triene-1-ketone, 2 to 3 parts of methyl n-nonyl acetaldehyde, 0.3 to 0.5 part of an antibacterial agent, and 3 to 5 parts of a binder. The invention also discloses a preparation method of the antibacterial glass fiber air filter paper. The filter paper prepared by the invention can effectively block various bacteria in the air under the coaction of various raw materials to achieve the antibacterial effect; the bacterium resistance and sterilization are carried out separately inside and outside the filter paper by different substances, thereby effectively improving the air filtering effect.

The invention belongs to the technical field of cosmetic nursing preparations and in particular relates to antibacterial anti-allergy type shaving cream and a preparation method thereof. The shaving cream mainly comprises the following ingredients in mass fraction: 12-16% of glycerol, 7-10% of butanediol, 6-10% of polyoxyethylene lauryl ether sodium sulfate, 4-8% of glyceryl monostearate, 16-20% of potassium cocoyl glycinate, 10-14% of cetyl alcohol ethyl hexanoate, 4-8% of isopropyl myristate, 2-4% of houttuynin, 3-5% of quercetin and 18-22% of water. The shaving cream is rich in foam, the foam is fine and smooth, skin is not tight after use, affinity with skin is good, and the shaving cream disclosed by the invention has good sterilizing effect and good prevention effect on allergy caused by metal.

The invention discloses a preparation method of antibacterial and antistatic coating and belongs to the technical field of coating preparation. The preparation method disclosed by the invention has the beneficial effects that montmorillonite and marble contain a large amount of metal oxides such as MgO, CaO and ZnO and the like, the metal oxides are inorganic antibacterial agent and are also goodconducting materials; both tea polyphenol and houttuynin have antibacterial and antiseptic effects, and by the fermenting action, the tea polyphenol and the houttuynin can be combined with inorganic minerals; compared with polyanilines with other structures, the polyaniline with a nanofiber structure has higher conductivity; carbon nanotubes have good mechanical property and electric property simultaneously, and by combination of polyaniline nanofiber with the copper-loaded surface and the carbon nanotubes with the copper-loaded surfaces, the conducting property of the coating is improved, simultaneously the coating has good antibacterial property and wear resistance; by adoption of a special spraying mode for loading copper, the copper can be almost loaded on the surfaces of the polyaniline nanofiber and the carbon nanotubes, so that the antibacterial property and the conducting property are improved and the preparation cost is greatly reduced.