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116 results about "Diethylstilbestrol" patented technology
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Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication, which is mostly no longer used. In the past, it was widely used for a variety of indications, including pregnancy support for women with a history of recurrent miscarriage, hormone therapy for menopausal symptoms and estrogen deficiency in women, treatment of prostate cancer in men and breast cancer in women, and other uses. Today, it is only used in the treatment of prostate cancer and less commonly breast cancer. While most commonly taken by mouth, DES was available for use by other routes as well, for instance, vaginal, topical, and by injection.
Making method and application of CdS sensitized TiO2 environmental estrogen photoelectrochemical sensor
ActiveCN104297305AImprove photoelectric conversion efficiencySave raw materialsMaterial electrochemical variablesAntigenAntigen capture
The invention relates to a making method and an application of a CdS sensitized TiO2 environmental estrogen photoelectrochemical sensor. The method uses TiO2 as an antigen capture substrate material, a CdS photoelectric active material is in situ generated on the surface of a Cd2<+> functional TiP nanomaterial maker modified electrode through a direct Na2S dropping technology, and CdS is irritated by an LED lamp of visible light wavelength to be converted to a photoelectric current signal. The substrate material TiO2 can be well matched with CdS energy band, so the photocurrent conversion signal of CdS is further improved, thereby the competitive photoelectrochemical immunosensor for ultra sensitive detection of estradiol, estriol, diethylstilbestrol, bisphenol A, nonylphenol, oestrone and other environmental pollutants is made.
Owner:UNIV OF JINAN
Electrochemical immunosensor for detecting diethylstilbestrol, preparation method and application thereof
InactiveCN102262125AEasy to detectHigh sensitivityBiological testingMaterial electrochemical variablesDiethylstilbestrolGraphene
The invention relates to a non-labeled electrochemical immune sensor for detecting diethylstilbestrol and a preparation method and application of the sensor. The immune sensor comprises a substrate electrode; and after nanometer gold is deposited on the surface of the substrate electrode, a graphene-diethylstilbestrol-chitosan complex is modified, and non-specific active loci are sealed by bovineserum albumin. The preparation method comprises the following step of: after depositing the nanometer gold on the surface of the substrate electrode, enveloping graphene and the diethylstilbestrol byusing chitosan and fixing to the surface of the electrode. In the immune sensor, on the basis of a competitive mode of immune reaction, the immune reaction is monitored by taking K3Fe(CN)6 as a probeand by differential pulse voltammetry, so the immune sensor can be used for detecting the diethylstilbestrol. The non-labeled electrochemical immune sensor has the characteristics of high sensitivityand specificity, quick on-site detection, low cost and the like; and a detection method is simple and wide in application range, the detection limit can reach 0.1 ng / ml, and the linear range is between 0.5 and 1,500 ng / ml.
Owner:NANJING NORMAL UNIVERSITY
Glassy carbon electrode modified electrochemical detection method for diethylstilbestrol
InactiveCN101059480AControl securityThe steps of the test method are simpleBiological testingMaterial electrochemical variablesDiethylstilbestrolRepeatability
The invention relates to an electrochemical check method of glass-carbon electrode decoration of estromon, belonging to electrochemical analysis technical field, comprising that electrode pretreatment, nanometer gold sol preparation, polyethylene imine-nanometer gold decorated glass carbon electrode preparation, more particularly comprising that preparing polyethylene imine decorated glass-carbon electrode and preparaing polyethylene imine nanometer gold decorated electrode, and using the polyethylene imine nanometer gold decorated electrode to test the content of estromon. The inventive decoration of the working electrode is simple and repeatable, while the decorated electrode has strong selective collection on estromon, better test repeatability and high sensitivity, while the check limit can reach 0. 001mug / g.
Owner:SHANGHAI JIAO TONG UNIV
Detection reagent kit and detection method for diethyl stilbestrol
InactiveCN101482562ASimple structureEasy to useMaterial analysisTime resolved fluorescence immunoassayCarrier protein
The invention provides a kit for detecting diethylstilbertrol and detection method thereof, belonging the the time resolution fluoroimmunoassay (TRFIA) technical field, capable of detecting the content of diethylstilbestrol (DES) in animal-source food, blood, urine and feedstuff. The kit uses the TRFIA to detect the DES and the mark immune response is the base of the detection. A micropore plate is coated by DES-carrier protein and added with DES standard or sample and then added with DES antibody. The free DES and the DES-carrier protein on the micropore plate complete the DES antibody and the DES antibody which is not bonded with the free DES or the DES-carrier protein is cleared away and added with the EU3+-goat anti-rabbit antibody, after labeling the immune reaction, the non-bonded EU3+-goat anti-rabbit antibody is cleared away. After adding the reinforcement liquid, the fluorescence intensity cps is detected using a time resolution fluorescence instrument and the fluorescence intensity is inversely proportional to the DES concentration in sample and the content of DES in sample can be determined according to the standard curve. The DES detection kit has features of simple structure, convenient use, cheapness, high sensitivity up to 1ng / mL.
Owner:JIANSGU INST OF MICROBIOLOGY
Diethylstilbestrol detection kit and detection method
InactiveCN101799472AImprove featuresIncreased sensitivityChemiluminescene/bioluminescenceBovine serum albuminDiethylstilbestrol
The invention discloses a diethylstilbestrol chemiluminescent detection kit, comprising a detection plate and a reagent. The reagent comprises an antibody which is a monoclonal antibody prepared by using a conjugate of diethylstilbestrol and bovine serum albumin as an immunogen. The diethylstilbestrol detection kit can realize quick and large-scale detection and has very high specificity and sensitivity, wherein the detection sensitivity reaches 0.016 ppb.
Owner:SHANGHAI VETERINARY RES INST CHINESE ACAD OF AGRI SCI
Making method and application of CdS sensitized TiO2 environmental estrogen photoelectrochemical sensor
InactiveCN104297495AImprove photoelectric conversion efficiencySave raw materialsBiological testingMaterial electrochemical variablesAntigenAntigen capture
The invention relates to a making method and an application of a CdS sensitized TiO2 environmental estrogen photoelectrochemical sensor. The method uses TiO2 as an antigen capture substrate material, a CdS photoelectric active material is in situ generated on the surface of a Cd2<+> functional TiP nanomaterial maker modified electrode through a direct Na2S dropping technology, and CdS is irritated by an LED lamp of visible light wavelength to be converted to a photoelectric current signal. The substrate material TiO2 can be well matched with CdS energy band, so the photocurrent conversion signal of CdS is further improved, thereby the competitive photoelectrochemical immunosensor for ultra sensitive detection of estradiol, estriol, diethylstilbestrol, bisphenol A, nonylphenol, oestrone and other environmental pollutants is made.
Owner:UNIV OF JINAN
Diethylstilbestrol dosage form and methods of treatment
InactiveUS20110189288A1Efficient deliveryLower testosterone levelsBiocidePowder deliveryActive agentWater soluble
Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, particularly diethylstilbestrol and pharmaceutically acceptable salts thereof to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract.
Owner:NAL PHARM LTD
Organic compound based on gallocyanine and application of organic compound
ActiveCN104098500AReduce distractionsQuick ViewOrganic chemistryColor/spectral properties measurementsChemical compoundGallocyanine
The invention relates to a probe used for detecting diethylstilbestrol, and in particular to an organic compound based on gallocyanine and application of the organic compound. The structure of the compound is shown as the formula I; the compound is taken as the probe detecting diethylstilbestrol. According to the invention, when diethylstilbestrol exists, remarkable change occurs to corresponding fluorescent intensity; the compound can be used for detection of diethylstilbestrol, greatly reduces interference of external detecting conditions, and improves detection precision; besides, remarkable change occurs to ultraviolet absorption when diethylstilbestrol exists; an ultraviolet spectrophotometer and naked eyes can be adopted for detection at the same time; the probe has the advantages that the probe is simple, convenient and quick to operate, visible in naked eye, low in cost, and wide in application range.
Owner:YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI
Multifunctional feed special for wood frog and polliwog
InactiveCN101331918AMeet nutritional needsImprove disease resistanceFood processingClimate change adaptationAntioxidantCorn meal
The invention relates to a multifunctional special feed for Tadpole of Rants chensinensis. The technical proposal adopted is that the feed consists of main materials and auxiliary materials; wherein, every ton of the main materials consists of 200 to 400kg of rice bran, 100 to 200kg of corn meal, 100 to 200kg of fish meal, 100 to 300kg of bean pulp powder, 100 to 200kg of meat meal, 50 to 100kg of wheat-middling and 20 to 70kg of wheat bran; every ton of the main materiala is added into the following auxiliary materials by weight: 200 to 800g of microbial inoculum agent, 200 to 500g of aquaculture vitamin complex, 200 to 500g of aquaculture compound mineral, 200 to 500g of antioxidant, 20 to 100g of inactivated aeromonas hydrophila vaccine and 20 to 50g of diethylstilbestrol. The preparation method is that firstly, the main materials are smashed, stirred; and then the auxiliary materials are added into the main materials and are stirred evenly, regulated in steam, granulated and cooled. The feed has the functions of sex induction and disease prevention for the Tadpole of Rants chensinensis.
Owner:LIAONING UNIVERSITY
Method for detecting diethylstilbestrol and special chemiluminescent immunoassay kit thereof
ActiveCN101936985AConducive to preservationImprove stabilityMicroorganism based processesTissue cultureSite monitoringChemiluminescent immunoassay
The invention discloses a method for detecting diethylstilbestrol and a special chemiluminescent immunoassay kit thereof. The chemiluminescent immunoassay kit for detecting diethylstilbestrol comprises a diethylstilbestrol specific antibody, a coating antigen and a standard solution, wherein the coating antigen is a conjugate of diethylstilbestrol hapten and carrier protein, and the constitutional formula of the coating antigen is as shown in a formula I. The detection method has the characteristics of simple preprocessing of samples, easy operation, low cost, high specificity, high sensitivity, high accuracy, and the like, and is capable for on-site monitoring and suitable for screening a large amount of samples.
Owner:CHINA AGRI UNIV
Protein chip for detecting multiple veterinary drug residues and kit thereof
InactiveCN101782580AAvoid potential hazardsAvoid pollutionMaterial analysis by observing effect on chemical indicatorVeterinary DrugsDiethylstilbestrol
The invention discloses a protein chip for detecting multiple veterinary drug residues and a kit thereof. The protein chip comprises a substrate and dot coatings of veterinary drug antibody, wherein the dot coatings are distributed in an array type, the substrate is a glass substrate or a membrane substrate; and the dot coatings of the veterinary drug antibody refer to eight types of veterinary drug antibodies, i.e. an anti-chloramphenicol antibody, an anti-chlorpromazine antibody, an anti-colchicin antibody, an anti-dapsone antibody, an anti-stilboestrol antibody, an anti-dimetridazole antibody, an anti-furazolidone antibody and an anti-metronidazole antibody which are uniformly distributed and in dot lattice on the substrate. The protein chip can obtain the reaction results with multiple indexes by only one-step reaction and can be suitable for simultaneously detecting eight veterinary drugs, i.e. chloramphenicol, chlorpromazine, colchicin, dapsone, stilboestrol, dimetridazole, furazolidone and metronidazole which are contained in a sample, thereby ensuring the safety and the sanitation of a large quantity of meat products.
Owner:上海裕隆生物科技有限公司
Method for measuring residual quantity of diethylstilbestrol in aquatic products by utilizing liquid chromatogram fluorescent method
InactiveCN101718755ALow limitLow costComponent separationWater bathsLiquid Chromatography-Fluorescence
The invention discloses a method for measuring residual quantity of diethylstilbestrol in aquatic products by utilizing a liquid chromatogram fluorescent method, comprising the following steps: (1) weighing 100g of ground aquatic product samples in a 50mL plastic centrifuge tube, adding 20mL of acetic ether, homogenizing for 230s, centrifuging for 10min with the speed of 7000r / min, moving the acetic ether layer to a 100mL pear-shaped flask, utilizing 2mL of normal hexane and acetic ether with a volume ratio of 85:15 to dissolve residue, and then stirring for 6min; (2) activating an SLH column by utilizing 5mL of normal hexane and 5mL of acetic ether, adding extracting solution on the SLH column, utilizing 10mL of normal hexane and acetic ether with the volume ratio of 82:20 to elute by controlling the flow rate at 2mL / min, collecting eluent, carrying water bath at the temperature of 450 DEG C, and then carrying out nitrogen drying till the original state; and (3) adding 1mL of sulfuric acid to the centrifuge tube of nitrogen drying, then adding 8mL of water in the centrifuge tube, utilizing 1mL of mobile phase for metering volume so as to be measured by an efficient liquid phase chromatogram. The method for measuring residual quantity of diethylstilbestrol in aquatic products has advantages of low cost, simple method, and low measuring limit, is suitable for popularization and use in the production and practice and is a technology demanded by the market, and has positive social meaning and social demand.
Owner:AQUATIC PROD RES INST SHANDONG PROV
ELISA reagent kit suitable for diethylstilbestrol residue analysis
InactiveCN101059511ALong storage timeThe pre-processing process is simpleBiological testingAntigenRadioactive contamination
The invention discloses an enzyme immunity adsorption check agent box used for analyzing the left depo-estromon, characterized in composed of an enzyme mark plate with the depo-estromon antigen, a sponge support, a concentrate washing agent (PBST), a depo-estromon standard product, a depo-estromon single-clone antibody, an enzyme mark two-antibody, a develop liquid and a reaction end liquid. In the check, the covered antigen absorbed on the hole wall of the enzyme mark plate competes with the object depo-estromon to react with the antibody, while the result is displayed via the development, checks the depo-estromon in known density and draws a standard curvature, to obtain the density of the object depo-estromon. The invention can accurately check the left depo-estromon in water and meat, with simple pretreatment, low time consumption, batch application, and low cost, while the agent has long service life and non radioactive pollution.
Owner:CHINA AGRI UNIV
Filter medium for removing diethylstilbestrol in water and preparation method thereof
InactiveCN101637715AWide variety of sourcesImprove water qualityOther chemical processesWater/sewage treatment by sorptionWater qualityFilter media
The invention discloses a preparation method of a filter medium for removing diethylstilbestrol in water. The preparation method comprises the following steps: a) mixing raw materials containing ultrahigh molecular weight polyethylene, active carbon, sepiolite powder, attapulgite powder and hole forming agent, wherein the weight ratio of the ultrahigh molecular weight polyethylene, the active carbon, the sepiolite powder, the attapulgite powder and the hole forming agent is 200-350:50-100:40-100:50-100:50-120; and b) pressing, sintering and cooling the obtained mixture in a mould. The invention also discloses the filter medium prepared according to the preparation method. Compared with the prior art, the invention can remove the diethylstilbestrol in the water with a removal rate of over 95 percent so as to achieve the aim of improving the water quality; in addition, the method is simple, and the raw materials for preparing the filter medium are widely available and have low cost. Thetechnical scheme is in particular applicable for the treatment of drinking water polluted by the diethylstilbestrol.
Owner:JOYPURE WATER PURIFICATION TECH CO LTD
Preparation method of diethylstilbestrol antibody
InactiveCN101914157AEasy to prepareLow costSerum immunoglobulinsImmunoglobulins against hormonesBovine serum albuminDiethylstilbestrol
The invention discloses a preparation method of a diethylstilbestrol antibody. The preparation method of the diethylstilbestrol antibody comprises the following steps of: (1) performing a reaction of diethylstilbestrol and 4-bromine butyric acid hexylester, exposing a carboxyl group by saponifying and hydrolyzing, and synthesizing diethylstilbestrol artificial haptene; (2) performing a reaction of the diethylstilbestrol artificial haptene and bovine serum albumin by a mixed anhydride method to obtain diethylstilbestrol artificial immunogen; and (3) emulsifying the diethylstilbestrol artificial immunogen and Freund's complete adjuvant (initial immunization) or Freund's incomplete adjuvant, subcutaneously injecting a rabbit, and separating blood serum when the antibody titer is stable to obtain the diethylstilbestrol antibody. The preparation method of the diethylstilbestrol antibody has the advantages of simpleness, convenience and low cost; and the prepared diethylstilbestrol antibody has high specificity, high antibody titer and indirect ELISA experimental antibody titer of over 1 million, can reduce detection cost when used for immunologically detecting diethylstilbestrol, and is easy to promote and use.
Owner:SOUTH CHINA AGRI UNIV
Efficient induction method and microsatellite molecular marker identification method of Nile tilapia pseudo-female fishes
InactiveCN106399293AEfficient inductionShorten the breeding cycleMicrobiological testing/measurementMutant preparationAgricultural scienceRapid identification
The invention discloses an efficient induction method and a microsatellite molecular marker identification method of Nile tilapia pseudo-female fishes. Different doses of estrogen diethylstilbestrol (DES) are used for sex reversal processing of different groups of Nile tilapia fishes to establish the efficient induction method of the Nile tilapia pseudo-female fishes; and a newly-developed microsatellite molecular marker tlp-23-sd and a primer thereof are further used for identification of the Nile tilapia pseudo-female fishes to establish the microsatellite molecular marker rapid identification method of the pseudo-female fishes, wherein the microsatellite molecular marker tlp-23-sd is closely linked with the sex. The efficient induction method is high in pseudo-female fish induction efficiency, and the microsatellite molecular marker rapid identification method is rapid, accurate and reliable in identification, and can be used for the production and identification of the Nile tilapia pseudo-female fishes.
Owner:SUN YAT SEN UNIV +1
GC-MS (gas chromatography-mass spectrum) measuring method of phenolic compounds in surface water
InactiveCN106093245AHigh sensitivityImprove accuracyComponent separationGas liquid chromatographicEarth surface
The invention discloses a GC-MS (gas chromatography-mass spectrum) measuring method of phenolic compounds in surface water, and belongs to the technical field of organic pollutants in water environment. The method is characterized in that in the water sample filtering, solid-phase extraction, purification and concentration processes, an ion monitoring GC-MS method is used for measurement; an internal standard method is used for quantification. The measuring method has the advantages that the detection on four kinds of phenolic compounds including octyl phenol, nonyl phenol, bisphenol A and diethylstilbestrol in the surface water has higher sensitivity, accuracy and precision; the measuring method hopefully becomes a new detection standard.
Owner:PEARL RIVER FISHERY RES INST CHINESE ACAD OF FISHERY SCI
Method for detecting diethylstilbestrol
InactiveCN101598713ARapid Field DetectionSimple methodComponent separationPotassium ferricyanideDiethylstilbestrol
A method for detecting diethylstilbestrol belongs to the field of analytical chemistry, wherein the method includes the followings: pre-treating the sample to be detected, preparing the sample solution and then carrying out the following treatments: adding sample solution at one end point of the paper chromatography strip; placing the paper chromatography strip in the normal hexane-ethanol developing solvent; taking out the paper chromatography strip when the front end of the developing solvent is adjacent to the front end of the paper chromatography strip; air-drying, wherein the normal hexane-ethanol developing solvent by volume includes: 1 to 20 parts of normal hexane, 0.1 to 5 parts of ethanol; spraying the potassium ferricyanide-ferric trichloride-H2O2 on the chromatography strip; color displaying, wherein the potassium ferricyanide-ferric trichloride-H2O2 is as follows: mixing the 0.01 to 5 mol / L aqueous solution of the potassium ferricyanide and the 0.01 to 5 mol / L aqueous solution of ferric trichloride evenly; then adding 0.001% to 5% of the H2O2 by volume 1 to 1; and the volume of the H2O2 is 0 to 10% of the total volume of the solution. The invention has the advantages of simple method and device, fast detecting speed and low detecting cost, and can be used for fastly detecting the DES in food on the spot.
Owner:SHANGHAI JIAO TONG UNIV
Diethylstilbestrol enzyme linked immunoassay reagent box and determination
InactiveCN1456894AThe pre-processing process is simpleThe detection method is simpleColor/spectral properties measurementsBiological testingAntigenDiluent
A chemical reagent box applies enzyme linked immunosorbent assay method to detect diethylstilbestrol. The cony IgG sensitizer is enveloped on the enzyme scale plate and the two are reacted through hatching, washnig, sample diluent and enzyme scale antigen adding after diethyl stilbestrol sensitizer is added. The detection is finished by washing, adding enzyme-substrate material to display coloure and using enzyme scale meter to detect A 450 nm.
Owner:JIANGNAN UNIV
Synthesis method of diethylstilbestrol compound methyl pigeon pea ketonic acid A
ActiveCN103772189AGet efficientlyMass synthesisOrganic compound preparationCarboxylic acid esters preparationAlkyl transferKetonic acids
The invention discloses a synthesis method of diethylstilbestrol compound methyl pigeon pea ketonic acid A. The synthesis method comprises the steps: esterifying a compound with a formula (I) to generate a compound with a formula (II); reducing the compound with the formula (II) to generate a compound with a formula (III); carrying out substitution on the compound with the formula (III) to generate a compound with a formula (IV); carrying out substitution on the compound with the formula (IV) to generate a compound with a formula (V); carrying out alkylation on the compound with the formula (V) to generate a compound with a formula (VI); carrying out esterolysis on the compound with the formula (VI) to generate a compound with a formula (VII); carrying out decarboxylation on the compound with the formula (VII) to generate a compound with a formula (VIII); carrying out dehydration cyclization on the compound with the formula (VIII) to generate a compound with a formula (IX); carrying out condensation on the compound with the formula (IX) to generate a compound with a formula (X); carrying out five-membered ring breakage on the compound with the formula (X) to generate a compound with a formula (XI); carrying out condensation on the compound with the formula (XI) to generate a compound with a formula (XII); carrying out coupling on the compound with the formula (XII) to generate a compound with a formula (XIII); carrying out esterolysis on the compound with the formula (XIII) to generate a compound with a formula (XIV), namely methyl pigeon pea ketonic acid A.
Owner:山东龙辰药业有限公司
Preparation method and application of electrochemical diethylstilbestrol sensor based on titanium-dioxide-based two-dimensional composite nanomaterial
InactiveCN105717178AEasy to makeEasy to operateMaterial analysis by electric/magnetic meansAntigenElectrochemical biosensor
The invention discloses a preparation method of an electrochemical diethylstilbestrol sensor based on a titanium-dioxide-based two-dimensional composite nanomaterial and belongs to the technical field of novel nano functional materials and biosensors. A novel two-dimensional flaky magnetic nano light-sensitive material FeCo-N@TiO2 is prepared firstly; through good bio-compatibility, the large specific area and ferromagnetism of the material, a diethylstilbestrol antibody is loaded, then horse radish peroxidase is fixed through the interlinking effect of glutaraldehyde, in the detection process, due to the fact that horse radish peroxidase can catalyze hydrogen peroxide, electrochemical signals are generated, through the influences of specific quantitative combination of the antibody and an antigen on electron transmission capacity, the current intensity is correspondingly reduced, and finally the electrochemical biosensor which is low in cost, high in sensitivity, good in specificity, rapid in detection and easy to prepare and detects diethylstilbestrol is prepared.
Owner:UNIV OF JINAN
Immunochromatographic test paper for detecting diethylstilbestrol and preparation method thereof
InactiveCN102253224ARapid and Sensitive AssayRealize objective measurementBiological testingAntigenCellulose
The invention discloses an immunochromatographic test paper for detecting diethylstilbestrol and a preparation method thereof. The immunochromatographic test paper for detecting diethylstilbestrol provided in the invention comprises a sample pad containing superparamagnetic composite particle marked antibodies to diethylstilbestrol, a cellulose nitrate membrane connected with one end of the pad and a water absorbing pad connected with another end of the cellulose nitrate membrane, wherein, the cellulose nitrate membrane is coated with a detection line and a quality control line which are mutually separated, the detection line contains diethylstilbestrol antigen, and the quality control line contains antiantibodies capable of specific binding to the antibodies to diethylstilbestrol. Experiments in the invention indicate that the test paper provided in the invention has the characteristics of high sensitivity, strong specificity, rapidness, simpleness and capacity of realizing objective detection in detecting diethylstilbestrol.
Owner:SHENZHEN GRADUATE SCHOOL TSINGHUA UNIV
Immune colloidal gold reagent for detecting stilboestrol and preparation method thereof
The invention is a kind of immune colloidal gold reagent for measuring the ethene estraphenol and the manufacturing method. The reagent includes a sample cushion, a colloidal gold combination cushion, aeotic acid cellulose film, a suction cushion and a PVC back lining, one end of the PVC back lining is adhered with sample cushion, colloidal gold combination cushion in order, the middle part is adhered with aeotic acid cellulose film, the other end is adhered with a suction cushion. The character lies in: the colloidal gold combination cushion is enclosed with a kind of ethene estraphenol resisting specificity single clone antibody-colloidal gold label, the aeotic acid cellulose film is enclosed by ethene estraphenol-BSA couplings and sheep (rabbit) antiplague IgG. The reagent has a strong specificity, high sensitivity, quick and simple, cheap, and convenient.
Owner:博顿生物检验技术(杭州)有限公司
Diethylstilbestrol compound and application thereof in preparation of drug for treating osteoporosis and hyperlipemia
InactiveCN103351285ADecreased lipid metabolismAbnormally decreased lipid metabolismEther separation/purificationMetabolism disorderBone densityLow density lipoprotein cholesterol
Owner:广州中医药大学热带医学研究所 +1
Fermentation control method
InactiveCN107384659AIncrease productivityQuality improvementBeer fermentationTemperature controlAgricultural engineering
The invention provides a fermentation control method which comprises the following steps: placing saccharified wheat juice into a corresponding yeast growing tank; after yeast proliferation, delivering raw material solution into a can body for further fermentation; when the fermentation temperature rises, guiding cooling alcoholic solution into a cooling jacket; when the fermentation degree of the appearance is 60%, closing a jacket cooling agent valve and raising the temperature naturally for bi-diethylstilbestrol reduction; after temperature rise, starting to seal a can for boosting and then fermenting; when the fermentation degree of the appearance is 65%, raising the temperature according to the preset rate; eliminating yeast for the first time and maintaining a certain pressure and temperature; emptying the yeast and filtering, so as to complete beer fermentation, wherein in the fermentation process, a temperature control module and a pressure control module are used for controlling temperature and pressure. The method provided by the invention is automatically controlled by a computer, the control method is flexible, the quality of beer is improved, the fermentation period is shortened, the system is stable and reliable, and the maintenance management is convenient.
Owner:广州百兴网络科技有限公司
Application and preparation method of dual-functional diethylstilbestrol non-enzymatic sensor constructed on basis of two-dimensional composite material
InactiveCN105758849AEasy to makeEasy to operateMaterial nanotechnologyChemiluminescene/bioluminescenceBiochemical engineeringElectrochemiluminescence
The invention discloses a preparation method of a functional nanomaterial based biological immunosensor with dual signal sending strategies of electrochemiluminescence and photoelectrochemistry.The sensor prepared according to the method has the advantages of simplicity in operation, portability, quickness in detection and low in cost and can be used for rapid and sensitive detection of diethylstilbestrol in fields of daily production, daily life and the like.
Owner:UNIV OF JINAN
Aspergillus niger for effectively degrading diethylstibestrol
InactiveCN104830699ABacterial source safetyEasy to operateFungiWater contaminantsMicroorganismMicrobiology
The invention relates to the field of environment treatment using microbes, and concretely relates to an Aspergillus niger for metabolizing diethylstilbestrol. The Aspergillus niger for metabolizing diethylstilbestrol is Aspergillus niger YAT, and the Aspergillus niger YAT is registered and preserved in China General Microbiological Culture Collection Center (CGMCC) on Feb. 11, 2015 with the preservation number of CGMCC No.10568. The Aspergillus niger can effectively degrade 20mg / L of diethylstilbestrol, and can be processed to develop corresponding environmentally friendly biological preparations, provides important resources for degradation or removal of diethylstibestrol residual in environment and foods, and has a good application prospect.
Owner:SICHUAN AGRI UNIV
Concrete release agent
InactiveCN104277901AImprove appearance qualityImprove the finishLubricant compositionCyclohexanoneSodium metasilicate
The invention relates to a concrete release agent comprising the following components in percentage by mass: 10%-15% of perfluorinated alkyl ethylene oxide, 10%-25% of fatty alcohol-polyoxyethylene ether, 12%-19% of a complexing agent, 14%-20% of n-butyl acetate, 6%-12% of formic acid, 8%-16% of methylphenol, 9%-15% of sodium metasilicate, 3%-8% of diethylstilbestrol, 6%-14% of acetone, 9%-15% of cyclohexanone, 6%-15% of potassium hydroxide, 3%-17% of etidronic acid, 40%-60% of pure water, and 8%-10% of a tribromosalicylaniline, triethanolamine and glycerinum mixture, wherein the weight ratio of tribromosalicylaniline to triethanolamine to glycerinum in the mixture is 2 to 7 to 1. The concrete release agent disclosed by the invention is capable of playing roles in protecting a template, improving the appearance quality of concrete, enhancing the surface smoothness of the film, and the like.
Owner:QINGDAO JIASHANG CREATIVE CULTURE
Preparation method of modified pollen and application thereof for absorbing and treating EDCs of water
InactiveCN103240061ASignificant progressWide variety of sourcesOther chemical processesWater/sewage treatment by sorptionEstroneTetrabromobisphenol A
The invention discloses a preparation method of modified pollen and the application thereof for absorbing and treating EDCs of water, which belong to a treatment method for sewage or wastewater. The preparation method disclosed by the invention comprises the following steps: washing natural pollen with ethanol; carrying out solid-liquid separation, drying and crushing; and adding the crushed product into a concentrated hydrochloric acid, sequentially carrying out ultrasonic dispersion and backflow filtering, washing to neutral, and drying, wherein the natural pollen is lotus pollen, piny flower pollen, apricot flower pollen and dandelion pollen. According to the application of the modified pollen for treating EDCs of waer, the modified pollen is added into water containing pollutants such as bisphenol A, estrone, 17beta-estradiol, estriol, progesterone, 17-alpha-ethinyl estradiol, 4-n-nonyl phenol, 4-t-octyl phenol, diethylstilbestrol or tetrabromobisphenol A. The pollen disclosed by the invention is small in polarity, hydrophobic, high in adsorbent active site and saturated adsorption amount, small in desorption ratio, renewable and reusable, therefore, the application is a way of treating water pollutions by using biomass materials.
Owner:云南中绿文德生态环保科技股份有限公司
Estradiol, estriol and diethylstilbestrol three-joint detection card and processing method of sample detected by same
InactiveCN102043060AEasy to manufactureLow detection costPreparing sample for investigationBiological testingAnimal scienceVeterinary Drugs
The invention relates to an estradiol, estriol and diethylstilbestrol three-joint detection card and a processing method of a sample detected by the same, belonging to the technical field of residue detection of estrogen veterinary drugs. A test strip is arranged in a housing of the three-joint detection card, a sample pad, a colloidal gold film, a nitrocellulose film and a water absorbing film are sequentially pasted on a supporting back plate, wherein the colloidal gold film is a glass fiber film containing an estradiol antibody, an estriol antibody and a diethylstilbestrol antibody colloidal gold marker, three detection strips are arranged on the nitrocellulose film and respectively comprise an estradiol protein coupling matter, an estriol protein coupling matter and a diethylstilbestrol protein coupling matter, and in addition, a quality controlling belt containing a rabbit antibody or mat antibody is arranged on the nitrocellulose film. The estradiol, estriol and diethylstilbestrol three-joint detection card can simultaneously detect estradiol, estriol and diethylstilbestrol contained in urine or feeds as well as animal tissues, meat and livers, and has the advantages of easiness to preparation, detection expense saving, convenience and quickness in use and accurate result.
Owner:无锡安迪生物工程有限公司
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