211 results about "Cyclobutane" patented technology

A polymer for ion conductor applications includes a polymer segment having a perfluorocyclobutyl moiety and a polymer segment not having such a moiety. One of these polymer segments is sulfonated to improve ionic conductivity. Fuel cells incorporating the ion conducting polymers are provided.

A process for the production of 4-hydroxybutyraldehyde is described. The process comprises reacting allyl alcohol with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst system comprising a rhodium complex and a trans-1,2-bis(bis(3,5-di-n-alkylphenyl)phosphinomethyl)-cyclobutane. The process gives high yield of 4-hydroxybutyraldehyde compared to 3-hydroxy-2-methylpropionaldehyde.

The invention provides a method for preparing baricitinib. The method comprises the following steps: by taking 4-pyrazol boric acid pinacol ester (10) as an initial raw material, performing Michael addition reaction on the initial raw material and 3-(icyanomethylene) azacyclo-cyclobutane-1-tert-butyl formate (11) so as to prepare an intermediate 12, and performing catalytic coupling reaction on 12 and 13, thereby preparing an intermediate 14; removing two-molecule tert-butyl formate of the intermediate 14, thereby preparing an intermediate 15; performing sulfamide reaction on the intermediate 15 and ethanesulfonyl chloride in an organic solvent, thereby obtaining a final product baricitinib (1). The method for preparing baricitinib has the advantages that the raw materials are easy to obtain, the process is simple, the operation is convenient, the reaction yield is high when being compared with that of document records, the atom utilization rate is high, industrial production can be easily achieved, and the like. The reaction general formula is as shown in the specification.

The present invention provides a polyimide precursor of a heat resistant transparent resin substrate material that is excellent in size stability, transparency and heat resistance, can be peeled froma supporting substrate to obtain a thin polyimide film, polyimide and a manufacturing method of a transparent polyimide film. The polyimide precursor has a structural unit originating from diamine, astructural unit originating from acid dianhydride, a structural unit originating from the 2,2'-bi (trifluoromethyl)-4,4'-diaminodiphenyl and a structural unit originating from the 1, 2, 3, 4-cyclobutane tetracarboxylic dianhydride. In all structural units originating from acid dianhydride, more than 70 mol% of structural units originating from 1, 2, 3, 4-cyclobutane tetracarboxylic dianhydride arecontained, and the light transmittance when carrying out the imide operation on the polyimide precursor to form the polyimide, is 5% or less at 308 nm and is 70% or more at 400 nm, and a coefficientof thermal expansion is 45 ppm / K or less.

A process for the production of 4-hydroxybutyraldehyde is described. The process comprises reacting allyl alcohol with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst comprising a rhodium complex and a diphosphine. The diphoshine is a trans-1,2 -bis(bis(3,4-di-n-alkylphenyl)phosphinomethyl)cyclobutane and / or a 2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis[bis(3,4-di-n-alkylphenyl)phosphino]butane. The process gives high yield of 4-hydroxybutyraldehyde compared to 3-hydroxy-2-methylpropionaldehyde.

Liquid crystalline compositions contain no functional group the synthesis of which is difficult, such as (meth)acrylate and epoxy group and comprise (A) an oxetane compound having an optically active portion, (B) a side chain liquid crystalline polymeric substance having an oxetanyl group, and (C) a photo cation generator and / or a thermal cation generator. The use of the composition can provide a cholesteric-aligned liquid crystal film with excellent alignment retention properties after being fixed in the liquid crystal state and mechanical strength, without employing any complicated step such as photo irradiation under an inert gas atmosphere.

The invention relates to a preparation method of diaminomethyl cyclobutane oxalate, which comprises the following steps: carrying out dimerization on acrylonitrile used as a raw material to generate a cis-dinitrile cyclobutane / trans-dinitrile cyclobutane mixture, carrying out distillation separation on the generated cis-dinitrile cyclobutane / trans-dinitrile cyclobutane mixture, and converting into trans-dinitrile cyclobutane by reduction; by using active nickel as a catalyst, introducing ammonia, and pressurizing with hydrogen to react, thereby obtaining trans-diaminomethyl cyclobutane; adding oxalic acid to obtain a crude diaminomethyl cyclobutane oxalate product; and finally, purifying with alcohol to obtain the finished diaminomethyl cyclobutane oxalate product. By using the method provided by the invention, the raw material is accessible, the operation is easy to control, the obtained product can be used as an intermediate to participate in the synthesis of Lobaplatin, and the obtained Lobaplatin has more stable properties and is more suitable for industrial production.

The invention discloses a polyimide film as well as a preparation method, a flexible substrate and application thereof. The polyimide is prepared by taking an aromatic dianhydride compound such as 3, 3 minute, 4, 4 minute-biphenyltetracarboxylic dianhydride (sBPDA), cycloaliphatic dianhydride compound 1, 2, 3, 4-cyclobutane tetracid dianhydride (CBDA) or 1, 3-dimethyl-1, 2, 3, 4-cyclobutane tetracid dianhydride (MCBDA) and an aromatic diamine compound as raw materials by virtue of a thermal imidization method. By adjusting the ratio of sBPDA and CBDA or MCBDA, the heat-resisting stability and optical transparence of the polyimide film substrate can be controlled. The film can be used as a flexible substrate to be applied to a flexible display device such as a flexible AMOLED (Active Matrix / Organic Light Emitting Diode), a flexible TFT-LCD (Thin Film Transistor Liquid Crystal Display) and the like.

The present invention provides a curable composition comprising a compound having a single partial structure containing a 4- or more-membered cyclic ether represented by the following formula (I) and a partial structure represented by the following formula (II): wherein in formula (II), R1 represents an alkylene group, a cycloalkylene group or an arylene group, and n represents an integer of 1 to 8.

The invention discloses a cation ultraviolet curing group-containing silicon oxide compound and a preparation method thereof. The preparation method is characterized by comprising the following steps of: mixing and stirring monohydroxy vinyl ether compound or monohydroxy-3-oxetane compound and methoxysilane in the presence of a catalyst in a molar ratio of (1-6)*n:1 until methoxyl group peak disappears in nuclear magnetic resonance spectroscopy; or mixing and stirring monohydroxy olefin compound and the methoxysilane in the presence of the catalyst in a molar ratio of (1-6)*n:1 until the methoxyl group peak disappears in the nuclear magnetic resonance spectroscopy, and then adding the obtained silicon olefin-containing compound dropwise into organic solution of organic peracid for performing epoxidation, wherein the number n of siloxicon bonds in molecules is an integer of 2 to 4. The preparation method has the advantages of low cost and readily available raw materials, simple and convenient preparation operation and convenient industrial production; and the obtained cation ultraviolet curing group-containing silicon oxide compound can be cured rapidly by ultraviolet irradiation; and the obtained coating has the advantages of high smoothness, high flame retardant efficiency and wide industrial application prospect.

The invention provides an environment-friendly chlorofluorocarbon-free refrigerant and a preparation method thereof. The refrigerant is prepared from propane, propylene, cyclobutane, 2,3,3,3-tetrafluoropropene, trans-1,3,3,3-tetrafluoropropene, trifluoromethyl iodide, pentafluoromethyl iodide, difluoromethane, tetrahydrothiophene, liquid carbon dioxide and cryogenic lubricant. The refrigerant has the beneficial effects that the ODP value is zero, the ozone sphere cannot be destroyed if the refrigerant is used for a long time; the GWP value of raw materials is low, and the working pressure of the refrigerant is equivalent to that of R22, so that an existing refrigeration system need not to be modified, the production cost can be reduced, while the refrigeration effect is not reduced; the refrigerant has the effects of inhibiting combustion and explosion, so that the combustibility of the refrigerant can be reduced, and the safety can be improved; the lubricant can seep into each part of a compressor together with the refrigerant so as to create an excellent condition for engine lubrication; tetrahydrothiophene is easily dissolved in difluoromethane and has a strong unpleasant smell, so that when the refrigerant leaks, a user can feel leakage of the refrigerant at the first time and carries out corresponding measures, so that property and safety of people can be protected.

The invention relates to a preparation method of diaminomethyl cyclobutane oxalate, which comprises the following steps: carrying out dimerization on acrylonitrile used as a raw material to generate a cis-dinitrile cyclobutane / trans-dinitrile cyclobutane mixture, carrying out distillation separation on the generated cis-dinitrile cyclobutane / trans-dinitrile cyclobutane mixture, and converting into trans-dinitrile cyclobutane by reduction; by using active nickel as a catalyst, introducing ammonia, and pressurizing with hydrogen to react, thereby obtaining trans-diaminomethyl cyclobutane; adding oxalic acid to obtain a crude diaminomethyl cyclobutane oxalate product; and finally, purifying with alcohol to obtain the finished diaminomethyl cyclobutane oxalate product. By using the method provided by the invention, the raw material is accessible, the operation is easy to control, the obtained product can be used as an intermediate to participate in the synthesis of Lobaplatin, and the obtained Lobaplatin has more stable properties and is more suitable for industrial production.

The present invention relates to ligands and catalyst systems for the hydroformylation of short and long chain olefins, preferably for the hydroformylation of ally alcohol producing 4-hydroxybutyraldehyde. The ligands disclosed herein are all-trans phosphinomethyl-cyclobutane ligands, such as, for example, all-trans-1,2,3,4-tetra[bis-(3,5-xylyl)phosphinomethyl]-cyclobutane. The catalyst systems comprise these all-trans phosphinomethyl-cyclobutane ligands in combination with an organometallic rhodium complex such as, e.g., (acctylacetonato)-dicarbonyl-rhodium (I). The ligands and catalyst systems of the present invention may be employed in the hydroformylation of olefins, in particular in the hydroformylation of allylalcohol, and provide improved selectivity and high reaction yields. wherein R1 is alkyl, preferably methyl, ethyl or propyl, R2 is H or an alkoxy group, R3 and R4, independently of one another, CH2OR1, CH2O-aralkyl, CH2OH,CH2—[P(3,5-R1,R1-4-R2-phenyl)2] or CH2O—(CH2—CH2—O)m—H (with m being an integer between 1 and 1.000).