308 results about "Cyclobutanes" patented technology

A process for preparing a polymer comprising sulfonating a perfluorocyclobutane polymer with a sulfonating agent to form a sulfonated perfluorocyclobutane polymer, wherein the sulfonating agent comprises oleum or SO3 is provided. A process for preparing proton exchange membranes and fuel cells comprising the proton exchange membrane are also provided.

This invention enables forming a photo-alignment film having a large LC anchoring strength in an IPS type liquid crystal display device. An alignment film is adapted to have a two-layer structure including a photo-alignment film and an alignment film with enhanced film strength. The photo-alignment film is formed of a precursor of polyamide acid ester, 80 percent or more of which is polyamide acid ester including cyclobutane. The alignment film with enhanced film strength is formed of a precursor of polyamide acid. After irradiating the substrate with ultraviolet light for photo-alignment, the substrate is heated. Thus, it is possible to achieve a high LC anchoring strength of the alignment film as the whole for photo-alignment, without degrading the mechanical strength of the alignment film with enhanced film strength.

The radiolabeled non-natural amino acid 1-amino-3-cyclobutane-1-carboxylic acid (ACBC) and its analogs are candidate tumor imaging agents useful for positron emission tomography and single photon emission computed tomography due to their selective affinity for tumor cells. The present invention provides methods for stereo-selective synthesis of syn-ACBC analogs. The disclosed synthetic strategy is reliable and efficient and can be used to synthesize a gram quantity of various syn-isomers of the ACBC analogs, particularly, syn-[18F]-1-amino-3-fluorocyclobutane-1-carboxylic acid (FACBC) and syn-[123I]-1-amino-3-iodocyclobutane-1-carboxylic (IACBC) acid analogs.

Optical waveguides interconnect optical information processing devices, or connect such devices with other optical communication links such as glass optical fibers. Fluoropolymers consisting of alternating perfluorocyclobutane and aryl ether linkages possess suitable properties for optical waveguides and other devices due to tunability in optical properties of the copolymers. Perfluorocyclobutane (PFCB) copolymer may be employed in solutions that exhibit a high solids content. Such solutions show useful physical properties for optical waveguide devices since the solutions are capable of achieving single step film thicknesses, when applied to a substrate, of greater than about 0.6 microns, and sometimes may achieve a thickness of 10 microns or more.

The present invention provides N,N′-dimethyl secondary diamine polymers including methylamine-terminated poly-(N-methylazetidine) and methylamine-terminated poly-(N-methylazacycloheptane). Amine compositions and amine-epoxy compositions comprising N,N′-dimethyl secondary diamine polymers are also disclosed.

The invention relates to a method for preparing a lobaplatin trihydrate by using oxalate, diaminomethyl cyclobutane oxalate, potassium chloroplatinite and potassium iodide are taken as raw materials, and the method comprises the following steps: firstly replacing the potassium chloroplatinite to potassium iodoplatinite, neutralizing the oxalic acid in diaminomethyl cyclobutane under alkaline condition, enabling the diaminomethyl cyclobutane to be freed, and then reacting the diaminomethyl cyclobutane with K2PtI4 (potassium iodoplatinate) for synthesizing a diiodide; enabling the diiodide to carry out replacement reaction with silver nitrate to generate silver iodide precipitate, enabling reactants after filtering out the precipitate to carry out ion exchange with anion exchange resin, then synthesizing a lobaplatin anhydride with lactic acid, re-crystallizing the anhydride in water / acetone mixed solution, and finally obtaining a lobaplatin trihydrate product. The raw materials used in the method have stable performances, the reaction is fuller and more complete, and the yield of the lobaplatin trihydrate is high.

New precursors and processes are provided to generate fluorinated low dielectric constant, .epsilon. films that have higher dimensional stability and more rigid than fluorinated Poly (Para-Xylylenes). The low .epsilon. films are prepared primarily from polymerization of precursors consisting of both benzocyclobutane and unsaturated carbon-carbon groups such as vinyl (C.dbd.C) and ethylenic groups. The low .epsilon. polymers consists primarily of SP.sup.2C--F, hyperconjugated Sp.sup.3C.sub..alpha.--F type or / and Sp.sup.3Si.sub..alpha.--F fluorine. The low .epsilon. (<2.4) films are useful for fabrications of future<0.18 .mu.m ICs. Using low .epsilon. films prepared according to this invention, the integrity of dielectric, Cu and its barrier metals such as Ta can be kept intact; therefore reliability of these ICs can be assured.

The invention relates to new benzocyclobutane, a preparation method thereof and application thereof. The invention provides a new preparation method for (1S)-4, 5-dimethoxy-1-(methyl-amino-methyl)-benzocyclobutane serving as a key intermediate of ivabradine hydrochloride and addition salt thereof, and meanwhile provides a new benzocyclobutane compound which is an intermediate for preparing the (1S)-4, 5-dimethoxy-1-(methyl-amino-methyl)-benzocyclobutane. In addition, the invention also provides a method for preparing the new benzocyclobutane compound, and meanwhile provides a method for splitting an intermediate product during preparing the new benzocyclobutane compound.

The invention provides liquid crystal alignment agents for photo-alignment, liquid crystal photo-alignment layers, and liquid crystal displays using the same. The liquid crystal alignment agents contain tetracarboxylic dianhydride mixture including cyclopentane tetracarboxylic dianhydride, which is reacted with specific diamine to obtain polyamide acid or its derivatives. The liquid crystal alignment agents are applied to form a photo-alignment film with excellent alignment property and high light transmittance, because of light sensitivity of the chemical change caused by illumination. In addition, the photo-alignment film is applied in liquid crystal displays, the electrical characteristics required by liquid crystal alignment film is satisfied, the voltage maintaince ratio is high, the iron amount is little, the remained charge amount is little, etc.

A liquid crystal display device includes: a pair of substrates, at least one of which is transparent; a liquid crystal layer placed between the pair of substrates; an electrode group, formed on at least one of the pair of substrates, for applying an electric field to the liquid crystal layer; and an alignment control film placed on at least one of the pair of substrates, in which the alignment control film is formed of polyimide and a precursor of the polyimide, each of the polyimide and the precursor of the polyimide contains, as a material, a specific cyclobutanetetracarboxylic acid dianhydride derivative and aromatic diamine, and the alignment control film is provided with alignment capability by photo-alignment treatment.

The present invention provides N,N′-dimethyl secondary diamine polymers including methylamine-terminated poly-(N-methylazetidine) and methylamine-terminated poly-(N-methylazacycloheptane). Amine compositions and amine-epoxy compositions comprising N,N′-dimethyl secondary diamine polymers are also disclosed.

Provided is a liquid crystal alignment film which suppresses afterimages caused by AC drive in an IPS- or FFS-driven liquid crystal display element, and which exhibits fast relaxation of residual charges accumulated by DC voltage. Also provided is a liquid crystal aligning agent suitable for use in a photo-alignment process in order to obtain the liquid crystal alignment film. The liquid crystal aligning agent suitable for use in a photo-alignment process comprises: at least one polymer (component (A)) selected from polyamic acid and imidized polyamic acid polymers obtained by reacting a tetracarboxylic dianhydride provided with a specific structure having a cyclobutane backbone, and a diamine compound that has at least one diamine selected from the group having the structures represented by formulae (D-1) and (D-2), and that has an amino group protected by a thermally cleavable group which is replaced by hydrogen at heating; at least one polymer (component (B)) selected from polyamic acid and imidized polyamic acid polymers obtained by reacting a tetracarboxylic dianhydride and a diamine compound which contains a diamine having a nitrogen-containing aromatic heterocycle such as pyridine; and an organic solvent.

The invention relates to a liquid crystal aligning agent, a liquid crystal aligning film and a liquid crystal display element. The invention provides a liquid crystal aligning agent which is provided with an excellent pretilt angle property by an optical alignment method, and can form a liquit crystal aligning film which does not result in poor display performance even when drived continuously for a long time. The liquit crystal aligning agent contains: (A) polyamide acid A, which is obtained by allowing tetracarboxylic dianhydride to react with diamines containing a diamine with a photoreactive structure; (B) polyamide acid B, which is obtained by allowing at least one tetracarboxylic dianhydride selected from a group composed of 1, 2, 3, 4-cyclobutane tetracarboxylic dianhydride, pyromellitic dianhydride to react with at least one diamine selected from a group composed of 2, 2'-dimethyl-4, 4'-diaminobiphenyl, p-phenylenediamine, 4, 4'-diaminodiphenylmethane, 4, 4'-diaminodiphenyl ether (with the polyamide acid A excluded).

The multicomponent mixed work medium throttling refrigerating agent applicable to 200-240 k temp. zone includes four groups of substances, respectively are: first group includes tetrafluoromethane, nitrogen trifluoride or mixture; second group includes ethylene, ethane, fluoroform, xenon, fluromethane, perfluoroethylene, fluoroethylene, perfluoroethane or their any two, three and several kinds or mixture of all them; fourth group includes 1-butylene, isobutane, 2-methyl butane, 1-pentene, 3-methyl-1-butylene, 2-methylpentane, 2-butylene, cyclobutane, isobutylene, n-butane, pefluorobutane, n-pentane, perfluoropentane or their two, three, several kinds ormixture of all the them; and third group includees propylene, propane, perfluoropropane, 1,1,1-trifluoroethane, 1,1,-bifluoroethane.

The invention relates to a method for preparing a lobaplatin trihydrate by using oxalate, diaminomethyl cyclobutane oxalate, potassium chloroplatinite and potassium iodide are taken as raw materials, and the method comprises the following steps: firstly replacing the potassium chloroplatinite to potassium iodoplatinite, neutralizing the oxalic acid in diaminomethyl cyclobutane under alkaline condition, enabling the diaminomethyl cyclobutane to be freed, and then reacting the diaminomethyl cyclobutane with K2PtI4 (potassium iodoplatinate) for synthesizing a diiodide; enabling the diiodide to carry out replacement reaction with silver nitrate to generate silver iodide precipitate, enabling reactants after filtering out the precipitate to carry out ion exchange with anion exchange resin, then synthesizing a lobaplatin anhydride with lactic acid, re-crystallizing the anhydride in water / acetone mixed solution, and finally obtaining a lobaplatin trihydrate product. The raw materials used in the method have stable performances, the reaction is fuller and more complete, and the yield of the lobaplatin trihydrate is high.

The present invention provides Mannich base derivatives of N,N′-dimethyl secondary diamine polymers including Mannich base derivatives of methylamine-terminated poly-(N-methylazetidine) and Mannich base derivatives of methylamine-terminated poly-(N-methylazacycloheptane). Amine curing agent compositions and amine-epoxy compositions containing Mannich base derivatives of N,N′-dimethyl secondary diamine polymers are also disclosed.

The invention provides a novel preparation method of Apalutamide. According to the novel preparation method, 2-fluoro-4-bromo-N-methyl benzene methanamine amide, 1-amino cyclobutyl carboxylate hydrochloride, and the like are taken as initial raw materials, and substitution reaction is carried out so as to obtain 1-((3-fluoro-4-(methyl carbamyl)phenyl)amino) cyclobutane-1-carboxylic acid, wherein synthesis yield is higher than 70%, and purity is higher than 97.2%; then esterification is carried out so as to obtain 1-((3-fluoro-4-(methyl carbamyl)phenyl)amino) cyclobutane-1-carboxylic ester, wherein synthesis yield is higher than 83%, and purity is higher than 97.8%; and at last, ring closing reaction with 2-cyan-3-trifluoromethyl-5-isothiocyano pyridine is carried out so as to obtain Apalutamide, wherein yield is higher than 68%, and purity is higher than 98.1%. The preparation method possesses following advantages: the raw materials are easily available; technology is simple; operationis convenient; yield is high; and cost is low.

The invention discloses an impurity removing method in the perfluoroethylene, which comprises the following steps: distilling perfluoroethylene gas with impurity in the degassing tower; controlling certain quantity to rectify in the extracting rectifying tower; adopting oligomer solvent of alcohols, ketones, chloroform and octafluorocyclobutane as extractant; combusting fluoride impurity gas on the top of rectifying tower; adsorbing the component from extracting rectifying tower autoclave; returning the component to rectifying unit directly to obtain the product.

An active energy ray-curable ink composition, which contains a compound having, in its molecule, an oxetane ring and at least one selected from a dioxolane ring, a dioxane ring, and a dioxepane ring; an ink composition, which contains a cationically-polymerizable compound having, in its molecule, both an oxetane ring and a bicycloorthoester ring; an inkjet ink, which contains the active energy ray-curable ink composition or the ink composition; and an image-forming method and a recorded material, using the inkjet ink; an oxetane compound of a specific structure.

The present invention discloses one kind of multicomponent mixture work medium suitable for fractional condensation type heat pump circulation system. The mixture work medium or mixed refrigeratant consists of two components, including one low boiling point component and one high boiling point component. The low boiling point component is one or several selected from difluro methane, trifluoro ethane, fluoro ethane, propylene, propane, pentafluoro ethane, etc. The high boiling point component is one or several selected from isobutane, n-butane, butene, isobutene, octafluoro isobutene, octafluoro cyclobutane, etc.

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein J is a phenyl optionally substituted with one to four substituents independently selected from R5; or J is a heterocyclic ring selected from the group consisting of J-1 to J-8; R4 is C4-C12 alkylcycloalkyl, C5-C12 alkenylcycloalkyl, C5-C12 alkynylcycloalkyl, C4-C12 cycloalkylalkyl, C5-C12 cycloalkylalkenyl, C5-C12 cycloalkylalkynyl, C4-C12 cycloalkenylalkyl or C4-C12 alkylcycloalkenyl; each optionally substituted with one to six substituents selected from CH3 and halogen; or R4 is C3-C5 oxiranylalkyl, C3-C5 thiiranylalkyl, C4-C6 oxetanylalkyl, C4-C6 thietanylalkyl, 3-oxetanyl or 3-thietanyl, each optionally substituted with one to five substituents independently selected from C1-C3 alkyl, C1-C3 haloalkyl, halogen, CN, C2-C4 alkoxycarbonyl and C2-C4 haloalkoxycarbonyl; or R4 is C3-C5 aziridinylalkyl, C4-C6 azetidinylalkyl or 3-azetidinyl, each with R10 attached to the nitrogen atom, and optionally substituted on carbon atoms with one to five substituents independently selected from Cl-C3 alkyl, C1-C3 haloalkyl, halogen, CN, C2-C4 alkoxycarbonyl and C2-C4 haloalkoxycarbonyl; and Rla. R1b, R2, R3 and R5 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

The invention provides a preparation method of lobaplatin and lobaplatin trihydrate. Trans-diamine methyl cyclobutane reacts and synthesizes with chloroplatinite in water at the atmosphere of inert gas to generate dichloride, wherein the trans-diamine methyl cyclobutane and the chloroplatinite are taken as raw materials, and the water serves as a solvent; replacement reaction is performed on the dichloride and silver nitrate, so that silver chloride sediments are generated after filtration; filter liquor reacts with L-lactic acid and / or L-lactate under a certain pH value condition so as to generate the lobaplatin; then water / acetone recrystallization is performed on the lobaplatin, so that high-purity lobaplatin trihydrate is obtained. The preparation method provided by the invention includes few reaction steps, and is short in reaction time, high in reaction efficiency, easy and convenient to operate and suitable for industrial production.

The invention relates to furan dicarboxylic acid copolyester and a preparation method thereof. The furan dicarboxylic acid copolyester has a structural formula as shown in a following formula (1), wherein x, y and z are integers of 10-90. The preparation method comprises the following steps: (1) mixing a dibasic acid or ester of the dibasic acid, dihydric alcohol and an esterification catalyst, and performing an esterification reaction in an inert atmosphere so as to obtain a first intermediate product, wherein the dibasic acid comprises furan dicarboxylic acid, and the dihydric alcohol includes ethylene glycol, 1,4-cyclohexane dimethanol and 2,2,4,4-tetramethyl-1,3-cyclobutane dimethanol; (2) performing a pre-polycondensation reaction on the first intermediate product under vacuum conditions so as to obtain a second intermediate product; and (3) performing a polycondensation reaction on the second intermediate product under vacuum condition so as to obtain the furan dicarboxylic acidcopolyester. The preparation method is simple, and the obtained furan dicarboxylic acid copolyester has excellent heat resistance, transparency and mechanical properties at the same time, and can be used for manufacturing baby nursing bottles, children toys, cups, kitchen utensils, electronic appliances and other products.

The invention relates to a radiation ray sensitive composition, a colour filter and a liquid crystal display used to form a coloured coat. The radiation ray sensitive composition used to form a coloured coat is characterized in that the composition contains (A) a pigment, (B) dispersant of which at least one of acid value and ammonia value is more than 0, (C) alkali soluble resins, (D) a multifunctional monomer, (E) optical polymerization initiator and (F) a polymer with repeated unit content of oxacyclobutane more than 70%. Even at a post-baking temperature of less than 200 DEG C, radiation ray sensitive composition used to form a coloured coat can form pixels and a black matrixes which are good in acid resistance to wide range of solvent and have good tightness with base plates.

A cation-polymerizable resin composition is provided which has a low viscosity, is easy to work with, and cures extremely rapidly when irradiated with light to obtain a cured product with excellent transparency, flexibility, heat resistance and post heat-treatment flexion. The cation-polymerizable resin composition of the present invention is characterized by containing: (A) an oxetane ring-containing vinyl ether compound, and / or (B) an alicyclic epoxy group-containing vinyl ether compound; (C) an oligomer or polymer having a molecular weight of at least 500 and having at least one of an oxetane group, epoxy group, hydroxyl group, vinyl ether group, an aliphatic or alicyclic unsaturated hydrocarbon group within the molecule; and (D) an oxetane compound having at least 6 carbon atoms and not having a vinyl ether group.

Provided is an efficient method for producing a 1,2,3,4-cyclobutane tetracarboxylic acid-1,2:3,4-dianhydride derivative which is useful as a raw material of polyimide or the like. The present invention is a method for producing a 1,2,3,4-cyclobutane tetracarboxylic acid-1,2:3,4-dianhydride derivative represented by formula (2) by photodimerization of a maleic anhydride compound represented by formula (1) under the presence of a benzophenone substituted with an electron-attracting group, an acetophenone substituted with an electron-attracting group, or a benzaldehyde substituted with an electron-attracting group. (1) (2) (In the formula, R is a hydrogen atom or an alkyl group having 1 to 20 carbon atoms.)

Provided is an efficient method for producing a 1,2,3,4-cyclobutane tetracarboxylic acid-1,2:3,4-dianhydride derivative which is useful as a raw material of polyimide or the like. The present invention is a method for producing a 1,2,3,4-cyclobutane tetracarboxylic acid-1,2:3,4- dianhydride derivative represented by formula (2) by photodimerization of a maleic anhydride compound represented by formula (1) in a diester carbonate solvent. (1) (2) In the formula, R is an alkyl group having 1 to 20 carbon atoms.

The production of 1, 1, 2-trifluoro-2-(trifluoromethyl)cyclobutane (TFMCB). More specifically, the present invention relates to a process for making 1, 1, 2-trifluoro-2-(trifluoromethyl)cyclobutane via a continuous catalytic reaction from commercially available raw materials ethylene and hexafluoropropene.

The invention relates to a liquid crystal directing agent, a liquid crystal directing film and a liquid display element. The invention provides the liquid crystal directing agent with great printing performance, voltage maintaining rate with high display and liquid crystal directing film with stable angle made by the technique conditions. The liquid crystal directing agent contains: (A) reacting the tetracarboxylic acid dianhydride containing 1,2,3,4-cyclobutane dianhydride and the diamine reaction to obtain polyamide acid; and (B) reacting the 4-carboxylic acid anhydride and containing the above-mentioned type (d-1), said compounds represented by a specific single-substituted benzene diamine diamine reaction of the polyamic acid dehydration of the closed-loop polyimide; the quantity of the amic acid structure of the (A) polyamic acid relevant to the has the sum quantity of the imide structure quantity and the amic acid structure of the (B) polyimide; the quantity ratio of the actidione of the (B) polyimide is 10-50%.