305 results about "Chemical binding" patented technology

These and other objects of this invention are achieved by providing a novel method and compositions for the clinical treatment of chronic inflammatory diseases. This invention involves use of systemically administered compositions which include primary amine derivatives of benzoic acid as carbonyl trapping agents. These primary therapeutic agents act by chemically binding to and sequestering the aldehyde and/or ketone products of lipid peroxidation. Increased levels of lipid peroxidation have been repeatedly demonstrated as a part of the non-enzymatic "inflammatory cascade" process which underlies the secondary etiology of chronic inflammatory diseases. p-Aminobenzoic acid (or PABA) is an example of the primary therapeutic agent of the present invention. PABA has a small molecular weight, is water soluble, has a primary amine group that reacts with carbonyl-containing metabolites under physiological conditions and is tolerated by the body in relatively high dosages and for extended periods. The carbonyl sequestering agents are used in combination with at least one co-agent so as to produce an additional beneficial physiological effect of an anti-inflammatory nature. Such compositions are administered systemically entirely via the oral route. Co-agents of the present invention include anti-oxidants and free radical trapping compounds (e.g., alpha-tocopherol), compounds having indirect anti-oxidant activity (e.g., selenium), vitamins (e.g., pyridoxine HCl), compounds which facilitate kidney drug elimination (e.g., glycine), metabolites at risk of depletion (e.g., pantothenic acid), sulfhydryl containing chemicals (e.g., methionine), compounds which facilitate glutathione activity (e.g., N-acetylcysteine), and non-absorbable polyamine co-agents (e.g., chitosan).

The invention belongs to the fabric water-repellent finishing and processing field, in particular relates a super hydrophobic cotton fabric and a preparation method thereof. The preparation method of the super hydrophobic cotton fabric is characterized in that the epoxy-functionalized modification is performed to the cotton fiber of fabric, then aminated nano-SiO2 and epoxy-functionalized nano-SiO2 are used to impregnate the cotton fabric in turn so as to increase the surface roughness of the fabric, finally a low-surface-energy material is adopted to perform hydrophobization treatment to the fabric; the contact angle between the prepared cotton fabric and water drops is more than 150 degrees; the method utilizes the covalent reaction of epoxy groups of cotton fabric, amino groups of nano-SiO2 and epoxy groups of nano-SiO2 to ensure the built rough surface to have good fastness; and the built surface has a large number of Si-OHs and epoxy groups so as to facilitate the chemical combination of the low-surface-energy material and the surface, thus the superhydrophobic property of the prepared fabric has excellent stability.

A process for chemically bonding an odor-encapsulating agent to textiles includes reacting a cyclodextrin with a cross-linking agent capable of forming ether bonds with the cyclodextrin and with the textile material, and curing the textile material treated with a mixture of the cyclodextrin and cross-linking agent. Preferably, the cross-linking agent is imidazolidone, which forms an ether bond with a hydroxyl group on the cyclodextrin and with a hydroxyl group. In textile materials containing cellulose, imidazolidone forms an ether bond with a hydroxyl group on the cellulose. An active agent can be complexed with the cyclodextrin for release. Textiles formed by such a process can comprise an article of clothing adapted to trap odors emanating from a wearer.

The invention discloses a preparation method of a novel MOFs-PVDF (Metal-Organic Frameworks-Polyvinylidene Fluoride) composite film. The preparation method is mainly characterized in that a synthesizing environment of MOFs is controlled to be consistent with a casting solution preparation condition, an organic ligand and metal ions are added into a casting solution by a simple one-step synthetic method, intermolecular acting force between the organic ligand and PVDF is regulated and controlled, the PVDF is chemically combined with the MOFs through a hydrogen bond of an 'F' atom, chemical bonding of a PVDF polymer and the MOFs is realized, and an MOFs-PVDF polymer is synthesized in the casting solution, so that the formation of a chemical bonding hole and the formation of an MOFs-PVDF novel film are performed simultaneously in a spinning process. The method is easy and efficient; moreover, the prepared film combines the advantages of an MOFs and PVDF composite film; the prepared novel MOFs-PVDF composite film has the advantages of high chemical stability, high mechanical strength, controllable aperture, large surface specific area and high porosity.

The cleaning-friendly article, such as a household kitchen appliance, which is suitable for heating food and/or directly connected with this unit, has a suitable long-lasting or permanent easily cleaned coating on its surfaces that are accessible to dirt. In order to provide this easily cleaned coating a mixture is applied to these surfaces, which contains a hydrolyzable, network-forming gel and a hydrophobic substance. The gel is preferably formed from metal oxides. such as SiO₂, Al₂O₃, Fe₂O₃, In₂O₃, SnO₂, ZrO₂, B₂O₃ and/or TiO₂. The hydrophobic substance is preferably chemically combined with the gel network. The hydrophobic substance preferably includes pre-condensed fluoroalkyl-silanes.

The invention provides a method to improve the storage stability for waste rubber powder modified asphalt. Wherein, the opposite compound comprises: 70~98.5% basic asphalt, 1~29.5% waste rubber, 0~10.0% diluent, and 0.1~5.0% coupling agent. The method comprises: adding the agents with given ratio into the waste rubber powder past 60-item screen to mix evenly; adding the treated rubber powder into asphalt to grinde for 30~190min by special device. As the alkoxy in coupling agent can form chemical bonding with inorganic filler to form organic active monomolecular layer between interfaces, this product can improve obviously the storage stability.

A mill blank assembly for a dental prosthesis includes a milling section and a support section for supporting the assembly in a milling machine. In certain embodiments, the milling section is adhesively bonded to the support section by a direct chemical bond that provides enhanced resistance to unintentional detachment of the milling section from the support section during a subsequent machining operation. Optionally, the support section includes a passageway that receives a quantity of flowable dental restorative material used to make the milling section, such that the restorative material that is located in the passageway provides additional resistance when hardened to unintentional detachment of the milling section from the support section.

Microarrays are made from sections of a molded block having many channels. These channels, which are formed by casting and/or embedding a rod in a moldable solid, are used to immobilize biological and chemical binding components after rod removal. The microarrays can be used in general biological assays, clinical evaluations and chemical library analyses.

The easily cleanable coated product is made by a process, in which a coating mixture including a hydrophobic and/or dirt-repellent substance uniformly distributed throughout a hydrolyzable, network-forming gel is applied to a product surface. The hydrophobic and/or dirt-repellent substance, which is a silane of the formula (CF_xH_y)—(CF_aH_b)_n—(CF_a′H_b′)_m—Si—(OR)₃, wherein R is an optionally heteroatom-containing, C₁–C₈-alkyl or aminoalkyl group and x and y each equal 0, 1, 2 or 3 and x+y=3, and a, a′ and b, b′ each equal 0.1 or 2, and a+b as well as a′+b′=2, and n and m each denote an integer from 0 to 20 and n+m equal at most 30, is chemically bound In the backbone of the gel network to form the easily cleanable coating. The gel is preferably an inorganic metal oxide gel made by a sol-gel process.

The present invention provides an integral source material, the integral source material has at least one nuclide that is an integral source material having at least one nuclide that is activatable by exposure to radiation, the nuclide is a chemically bound constituent of a polymer of the integral source material, wherein the integral source material is configured before activation to provide a device.

The objective of the present invention is to provide chimeric phage-derived particles, that may be used as safe food grade vehicles to for presenting various factors (e.g. antigens, virulence proteins, receptors, ligands, etc.) for living cells. In addition to at least one normal phage or virus component the particles comprise at least one additional factor that is not encoded by the genetic material of the chimeric particle. Applications for such particles include, but are not limited to, vaccine development, pathogen neutralization, chemical binding and/or neutralization (e.g. toxins), and competitive exclusion. In addition, this technology may be used to extend the retention time of phage particles during phage therapy and/or specifically target a given particle for a biofilm.