43 results about "Blood pressure increase" patented technology

A fluid delivery device is provided for delivering fluid to a target site such as an intervertebral disc during discography. The fluid delivery device includes pressure and volume sensors to determine the pressure and the volume of the fluid delivered to the intervertebral disc. The fluid delivery device is hand-held during use and includes a syringe assembly having a plunger with threads that enables controlled discharge of the fluid from the fluid delivery device by rotating the plunger in a housing of the fluid delivery device. The fluid delivery device may also include a communication module to wirelessly transfer data to an external device outside of a sterile field, while the fluid delivery device is in the sterile field. The fluid delivery device may also include a physiological sensor to monitor involuntary pain responses based on changing physiological parameters such as increases in body temperature or blood pressure.

The invention provides a production method for beef and mutton dried sausage, and relates to the technical field of food processing. The method comprises the steps of preparing cured meat, preparing cured additives, curing, drying and steaming. The cured additives are added with traditional Chinese medicine materials beneficial to human body. The dried sausage has the effects of resolving phlegm,reducing internal heat, strengthening the spleen and stomach and moistening the lung to engender fluid. The effect of the traditional Chinese medicine is combined in the meat, so that blood lipid rise and blood pressure increase which are caused by eating meat can be prevented; delicious meat quality is maintained; and disadvantages of conventional dried sausages are overcome.

The invention relates to a preparing and processing method of a prepared aconite slice. The preparing and processing method comprises the following steps of: carrying out heat treatment on a raw aconite slice at 102-240 DEG C for 0.25-2 hours; then drying to obtain the prepared aconite slice, wherein the heat treatment is preferably carried out under the damp and hot condition with water vapors at 102-108 DEG C for 0.5-2 hours or carried out under a 140-240 DEG C dry and hot condition for 0.25-1 hour. Experiments indicate that the prepared aconite slice prepared and processed through the method disclosed by the invention can outstandingly reduce the content of a toxic component, namely diester-type alkaloid, and can also retain the dopamine hydrochloride and salsolinol which are the cardiotonic and blood pressure increasing effective components of monoester-type alkaloid and aconite, thereby ensuring the exertion of the recuperating, rescuing, cardiotonic and blood pressure increasing drug effect of the prepared aconite slice.

The present invention relates to benzoimidazole-carboxylic acid amide compounds of the formula I, in which R′, R″, R′″, R1, R2, R3, R4, R5, R6 and Z are defined as indicated below. The compounds of the formula I are APJ receptor modulators, and are useful for the treatment of diseases associated with increased blood pressure for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.

The invention discloses a sphygmomanometer for dynamic monitoring of blood pressure, which is characterized by comprising a sleeve band and a host, the host comprises a measuring module, an air pump and an exhaust valve, the measuring module is connected with the air pump and the exhaust valve, is also connected with the sleeve band through an air pipe and comprises a central processing unit, a sensor, an A / D (analog / digital) conversion circuit, an acceleration sensor, a display processing unit, a key processing unit and a buzzer, and the central processing unit is respectively connected with the air pump, the exhaust valve, the A / D conversion circuit, the acceleration sensor, the display processing unit, the key processing unit and the buzzer circuit; and the sensor is respectively connected with the sleeve band and the A / D conversion circuit. The invention has the advantages that actions of patients can be monitored, pre-warning can be uttered in case of actions resulting in high blood pressure and thus the damage of high blood pressure to the patients as a result of excessive movement can be avoided.

The invention relates to a blood-pressure-treating traditional Chinese medicine composition, and specifically relates to a nerve-soothing blood-pressure-reducing traditional Chinese medicine tea. The invention provides the tea aiming at solving a series of health problems caused by increased blood pressure due to higher mental dysfunction caused by fast life pace, increased work pressure, and inappropriate diet and rest. The nerve-soothing blood-pressure-reducing traditional Chinese medicine tea is composed of the raw materials, by weight: 30-120 parts of mulberry leaves, 25-125 parts of hawthorn leaves, 20-100 parts of eucommia leaves, 20-100 parts of Japanese pogodatree flower, 15-75 parts of white chrysanthemum, 10-50 parts of Szechwan lovage rhizome, 10-50 parts of obtuseleaf senna seed, and 10-50 parts of ginkgo leaves. When the nerve-soothing blood-pressure-reducing tea provided by the invention is taken for a long time, human body functioning can be gradually improved. The tea has the functions of human central nervou regulating, fatigue relieving, sleep promoting, body immunity enhancing, human body self-regulation enhancing, and blood pressure fluctuation suppressing.

The invention belongs to the technical field of medical instruments, and particularly relates to a cardiovascular clinical compression rapid hemostasis device. The cardiovascular clinical compressionrapid hemostasis device comprises a vertical column, a rotating shaft, a fixed plate, a first air cylinder, a pressing head and a controller. One end of the rotating shaft is inserted into a first cavity formed in the upper end of the vertical column, and the rotating shaft is fixedly sleeved with a rotating ring in the first cavity; the side wall of a first groove is slidably connected to a circumferentially arranged electric push rod; the driving end of the electric push rod is hinged to a first hinge rod and a second hinge rod; a second groove is formed in the lower surface of the pressinghead; a third groove is formed in the lower surface of the pressing head; a third cavity is formed in the interior of the pressing head. The cardiovascular clinical compression rapid hemostasis device, while carrying out pressing hemostasis, can realize the intermittent intelligent adjustment of the pressing force and intermittent release of the buffer to ensure the necessary blood supply demand and to avoid the occurrence of blood pressure increase, and further can improve the hemostasis effect through circulating of ice water in combination with a hemostatic powder medical solution.

The invention discloses an establishing method of a hypertensive disorder complicating pregnancy mouse model. The establishing method of the hypertensive disorder complicating pregnancy mouse model comprises the following steps of: extracting a syncytiotrophoblast microvilli membrane; and inputting the syncytiotrophoblast microvilli membrane to a pregnant mouse body of the same strain by caudal vein injection to establish the hypertensive disorder complicating pregnancy mouse model. The hypertensive disorder complicating pregnancy mouse model established by the establishing method disclosed by the invention has hypertensive disorder complicating pregnancy characteristic symptoms and signs including elevation of blood pressure, eclampsia hyperspasmia, damages to heart and liver and the like, which are consistent with the symptoms and pathological process of the hypertensive disorder complicating pregnancy including eclampsia and the like at the early stage of the human eclampsia, and therefore, the hypertensive disorder complicating pregnancy mouse model can be used for researching the occurrence and development mechanism of the hypertensive disorder complicating pregnancy including eclampsia and the like at the early stage of the eclampsia, as well as the medical foundation with the purpose of developing antagonistic medicaments and the clinical research.

The invention discloses a continuous intravenous administration device for animal blood pressure increasing and reducing tests. The device comprises a liquid supplementing bottle, a first three-way pipe, an air filter, a second three-way pipe and a puncture needle; the liquid supplementing bottle, the first three-way pipe, the air filter, the second three-way pipe and the puncture needle are sequentially communicated through a hose; a control switch is arranged on the first three-way pipe, a quantitative liquid supplementing device is inserted into the rest pipe opening of the first three-waypipe, the control switch controls the quantitative liquid supplementing device to be communicated with the liquid supplementing bottle or the air filter, and a quantitative administration device bodyis inserted into the rest pipe opening of the second three-way pipe. The invention provides an administration method of the administration device. On the basis of the administration method of the administration device, administration is conducted through the administration device after gas in the hose, the first three-way pipe, the second three-way pipe and the puncture needle is exhausted. According to the continuous intravenous administration device for the animal blood pressure increasing and reducing tests and the administration method thereof, administration is convenient, and on the premise that administration can be independently completed by one person, accurate administration can be achieved, and the dosage of pushed liquid can be controlled.

The invention relates to the technical field of medical instruments, in particular to a portable hemostasis compression device for the department of cardiology and a use method thereof. The technical problems that only solid pressing can be achieved, intermittent buffer release is difficult to achieve to guarantee necessary blood supply requirements, only fixed pressing force and pressing intermittence can be achieved, the using effect is poor, leakage-proof cleaning of blood exuding from a wound is difficult to achieve, and pollution is likely to be caused to the outside are solved. In order to solve the technical problem, the portable hemostasis compression device for the cardiology department and the use method thereof are provided, the portable hemostasis compression device for the cardiology department is composed of an intermittent compression mechanism and an adjusting mechanism, intermittent buffering and releasing can be achieved, the necessary blood supply requirement is guaranteed, and blood pressure rising is avoided; the pressing force and intermittent control can be conveniently adjusted according to the pressing requirement and the actual condition of a patient, closed protection can be formed on the puncture position, the external influence is avoided, and exuded blood can be discharged to avoid pollution.

The invention discloses an ambulatory blood pressure feature extraction method for obstructive sleep apnea syndrome (OSAHS). The method comprises the following steps: extracting the following parameters from 24-hour ambulatory blood pressure monitoring data of a subject, comprising: at least a part of: nighttime blood pressure rise effective height, nighttime blood pressure rise maximum height, nighttime blood pressure rise duration, nighttime blood pressure rise slope, nighttime blood pressure fluctuation frequency, nighttime blood pressure base line upper area, nighttime blood pressure base line lower area, nighttime blood pressure drop effective height, nighttime blood pressure drop maximum depth, nighttime blood pressure drop duration, a nighttime blood pressure decrease slope, a nighttime blood pressure secondary increase duration, a nighttime blood pressure secondary increase slope, a nighttime blood pressure fluctuation frequency, a morning peak blood pressure increase maximum height, a morning peak blood pressure increase duration, a morning peak blood pressure increase slope, a morning peak blood pressure decrease duration, a morning peak blood pressure decrease slope, and an area on a morning peak blood pressure baseline.

Compositions comprising potassium taurate bicarbonate complexes and / or potassium taurate ascorbate complexes are useful as pharmaceutical compositions and as dietary ingredients in nutritional supplements, medical foods, and other foods. In preferred embodiments, potassium taurate bicarbonate and / or potassium taurate ascorbate complexes are the active ingredient in antihypertensive drug products that are intended to lower or prevent elevated blood pressure, or as dietary ingredients in dietary supplements, medical foods or other foods that are intended to supply a source of potassium, taurine, ascorbate, and / or bicarbonate, or that are intended to help maintain normal blood pressure levels and / or normal muscle mass. In preferred embodiments, potassium taurate bicarbonate complexes are prepared by intermixing potassium bicarbonate and taurine in aqueous solutions, and potassium taurate ascorbate complexes are prepared by intermixing potassium ascorbate and taurine in aqueous solutions.

The invention relates to the technical field of traditional Chinese medicine, in particular to a healthcare tea capable of reducing blood pressure and suitable for women. The healthcare tea capable of reducing blood pressure and suitable for women is prepared from, by mass, 20-25 parts of rhizoma curculiginis, 15-21 parts of black tea, 15-21 parts of herba epimedii, 15-21 parts of peach kernels, 15-21 parts of flos carthami, 10-16 parts of rhizoma anemarrhenae, 15-20 parts of cortex phellodendri, 10-16 parts of radix rehmanniae preparata, 15-20 parts of radix angelica sinensis, 15-20 parts of rhizoma chuanxiong, 10-18 parts of radix platycodi, 10-18 parts of cortex moutan, 10-14 parts of flos chrysanthemi indici, 10-14 parts of folium apocyni veneti, 8-12 parts of herba siegesbeckiae, 8-12 parts of inula flower, 8-12 parts of rhizoma atractylodis macrocephalae, 5-9 parts of fresh ginger, 5-9 parts of cortex eucommiae, 5-9 parts of Chinese starjasmine stems and 4-7 parts of radix pueraiae. The healthcare tea capable of reducing blood pressure and suitable for women can nourish liver and kidney, harmonize chong and ren channels, reduce blood pressure and stabilize blood pressure, and is especially suitable for women before and after menopause when symptoms like instable blood pressure, emotional fluctuation, and blood pressure increase accompanied by dizziness and headache, vexation and irritability and swelling pain of lateral thoraxes on two sides are shown.

The invention discloses a foreign wine formula, which is characterized by comprising tea, sappan wood, grape, and a Chinese sorghum edible liquor formula. The foreign wine can prevent oxidation, sudden mutation and tumors, and is capable of reducing the contents of cholesterol and low density lipoprotein in blood, inhibiting the blood pressure increasing and platelet aggregation, preventing the bacterium and cancers, prolonging the life span, and relieving the allergic phenomenon.

The invention discloses a traditional Chinese medicine for regulating blood pressure. The traditional Chinese medicine for regulating the blood pressure is characterized by being prepared from a systolic pressure reducing agent, a diastolic pressure reducing agent, a differential pressure reducing agent, a differential pressure amplifying agent, a blood pressure stabilizing agent, a blood pressure increasing agent, a dehumidifying and pressure regulating agent and a detoxification and stasis removing antihypertensive agent. Compared with the existing drugs of treating abnormal blood pressure, the traditional Chinese medicine for regulating the blood pressure adopts pure natural medicine materials, and the clinical experience proves that the traditional Chinese medicine for regulating the blood pressure can effectively regulate blood pressure and has no side effects on patients.

The invention provides a preparation method of 9-bit-substituted double functional group berberine derivatives and belongs to the field of chemical synthesis. A pharmacological experiment proves that the derivatives have drug activity with a plurality of values and especially, the derivatives have the easy absorption performance which does not belong to a single function group drug. An animal experiment proves that the derivatives have excellent effects of adjusting hypertension rat blood pressure. The 9-bit-substituted double functional group berberine derivatives can prevent bonding of angiotensins II obtained through various approaches and their special acceptors so that blood pressure increasing effects are reduced or inhibited.

The invention provides a formula and a production process of an intestinal tract cleaning and detoxification health food, and relates to the field of traditional Chinese medicine health care products, wherein the components of the intestinal tract cleaning and detoxification health food comprise, by weight, 5-17 parts of enzyme, 3-8 parts of sea salt, 6-19 parts of citric acid, 5-25 parts of dried celery powder, and 15-35 parts of dried carrot powder. According to the present invention, the intestinal tract cleaning and detoxification health food is made from the pure natural materials, does not contain any chemical additives, does not have toxic-side effect, can clear digestive tract stool, intestinal poison, heavy metal ions and the like, provides clean and complete effects, cannot cause blood pressure increasing, blood sugar increasing and the like, and can provide reducing effects in high blood pressure, hyperglycemia, thick blood fat and the like, wherein the whole detoxification effect is more than 99%.

The invention relates to the field of cherry processing and discloses cosmetic cherry dry red wine which is prepared from, by weight, 200-300 parts of cherry, 25-30 parts of aloe, 15-20 parts of longan, 10-15 parts of raspberry, 5-10 parts of motherwort honey and 0.2-0.3 part of wine yeast. Antioxidation effect of cherry seeds, which is neglected by people, is utilized fully, and the cherry seeds are added into fermentation liquid, so that the cherry dry red wine obtained through two times of fermentation is strong in fruit aroma, remarkable in refreshing and skin-beautifying efficacy and unique in medical value and has effects of treating anemia, softening blood vessels, improving circulation, preventing diseases and beautifying face if being drunk for a long time properly; the dry red wine is high in selenium content, selenium is a strong oxidant, and selenium together with vitamin E can prevent and treat angina and myocardial infarction and prevent blood pressure increase and thrombosis.

The invention discloses application of a P2X7 antagonist in preparation of medicament for treating myocardial ischemia injuries and hypertension / sympathetic nervous system diseases. Myocardial ischemia causes sympathetic excitoreflex (elevation of blood pressure, acceleration of heart rate and respiration and the like), and then myocardial ischemia injuries are aggravated. Cardiac sympathetic nervous erethism can also cause the elevation of blood pressure and then cause hypertension. The invention discloses a P2X7 receptor antagonist oxATP which can be used for reducing sympathetic nervous reflex caused by myocardial ischemia injuries and avoiding the phenomenon that myocardial ischemia and hypoxia are further aggravated due to cardiac sympathetic erethism, so that the myocardial ischemia injuries are relieved or alleviated. The hypertension can be prevented and cured by inhibiting cervical sympathetic ganglion erethism transmission. Sympathetic nervous diseases can be prevented and cured by inhibiting sympathetic erethism and related pathological processes. The mechanism of action of the oxATP in preventing and treating myocardial ischemia injuries, hypertension and sympathetic nervous lesions is as follows: the sympathetic excitation transmission mediated by cervical sympathetic ganglion P2X7 accepter is blocked, and an effect of preventing and treating the myocardial ischemia injuries, hypertension and sympathetic nervous diseases is generated.

The invention discloses a gene-ATF4 capable of retarding blood pressure rise in high-salt induced mice and relates to the field of medical technologies. According to the function of the gene-ATF4 capable of retarding the blood pressure rise in the high-salt induced mice on high blood pressure of the high-salt induced mice, it is discovered that the blood pressure rise in the high-salt induced micecan be retarded by knocking the ATF4 out or down, and blood vessels are protected by knocking the gene-ATF4 out or down.

The invention provides a multi-purpose portable sphygmomanometer. The multi-purpose portable sphygmomanometer comprises a zero / full scale switching unit, a pressure measurement unit, a condition judgment unit, a parameter calculation unit, a parameter storage unit and a pressure calibration unit, wherein all the units are matched with each other, so that the static-pressure automatic correction function is realized. The multi-purpose portable sphygmomanometer is characterized in that the zero / full scale switching unit is used for switching pressure values OmmHg and 300mmHg, so that the electronic sphygmomanometer can conveniently collect an initial value, the pressure calibration unit is used for calling out pressure proportion parameters stored in the Flash, so that the collected initial value is converted into the calibrated pressure value. With the multi-purpose portable sphygmomanometer, the blood pressure value can be monitored at any time, meanwhile, when faint suddenly occurs due to blood pressure increase, a user can pull out a pull ring smoothly for pulling out the pull rod, so that defensive alarming is realized, then the help from others surrounding the user is obtained, moreover, the multi-purpose portable sphygmomanometer can be used as an electric torch when the user goes out at night, and alarming can be started under the circumferences such as robbery, so that the problem that the existing portable sphygmomanometer is single in function is solved.

The invention discloses a traditional Chinese medicine formula for relieving hypertension and relates to the technical field of traditional Chinese medicine formulae. The traditional Chinese medicineformula is characterized by consisting of the following raw materials in parts by weight: 20 parts of American ginseng, 10 parts of pine needles, 10 parts of radix codonopsis pilosula, 10 parts of radix ophiopogonis and 5 parts of Chinese magnoliavine fruits. The traditional Chinese medicine formula has the beneficial effects that the traditional Chinese medicine formula is adopted, respective effects of the traditional Chinese medicine components are utilized and matched with one another, and blood pressure of a patient suffering from hypertension can be effectively controlled; the medicine can be taken by the patient for a long time, is good in security and free of toxic or side effect; and for a patient suffering from sudden blood pressure increase, a hypotensive drug can be additionally taken to reduce the blood pressure rapidly, and the medicine can be taken to keep the blood pressure stable in long-term treatment, the blood pressure can be kept at a normal level, and complications caused by unstable blood pressure can be retarded.

The invention provides essence capable of expelling dampness and reducing fat and a preparation method of the essence capable of expelling dampness and reducing fat. The formula comprises sambucus thunbergiana, Chinese mugwort, lavender, tea polyphenols and amino acids. The essence capable of expelling dampness and reducing fat further comprises rose essential oil, fennel seed essential oil and acompatibilizer. Through the compounding ratio of all the components, the herbal essence is mainly used for expelling dampness, reducing fat, recuperating meridians, improving sleep and strengthening body immunity, has the efficacy of improving sub-health, can effectively achieve the effects of dispelling the wind, promoting urination, warming and activating meridians, promoting blood circulation for removing blood stasis, reducing appetite, reducing fat, adjusting endocrine and improving insomnia, and can effectively prevents occurrence of serious side effects of elevation of blood pressure, anorexia, hepatic dysfunction and the like caused by eating weight reducing foods in the prior art.

The invention relates to the field of cherry processing and discloses cosmetic cherry dry red wine which is prepared from, by weight, 200-300 parts of cherry, 25-30 parts of aloe, 15-20 parts of longan, 10-15 parts of raspberry, 5-10 parts of motherwort honey and 0.2-0.3 part of wine yeast. Antioxidation effect of cherry seeds, which is neglected by people, is utilized fully, and the cherry seeds are added into fermentation liquid, so that the cherry dry red wine obtained through two times of fermentation is strong in fruit aroma, remarkable in refreshing and skin-beautifying efficacy and unique in medical value and has effects of treating anemia, softening blood vessels, improving circulation, preventing diseases and beautifying face if being drunk for a long time properly; the dry red wine is high in selenium content, selenium is a strong oxidant, and selenium together with vitamin E can prevent and treat angina and myocardial infarction and prevent blood pressure increase and thrombosis.

The invention relates to a VEGFR inhibitor and blood pressure reducing medicine composition. The composition is a composition of Axitinib and Losartan. The medicine composition lies in combined use ofAxitinib and Losartan, and in vivo experimentation on animals confirms that compared with single medicine of the Axitinib, the composition not only has notable treatment effects on carcinoma of kidney, but also notably reduces side effects of elevation of blood pressure, liver enzyme, elevation of serum creatinine caused by the Axitinib. The VEGFR inhibitor and blood pressure reducing medicine composition is controllable for side effects of antitumor drugs for targeting VEGFR, and a new research thought train is provided for clinical application of target medicines.

The invention discloses low-sodium health-care salt suitable for patients suffering from high blood pressure. The particle size range of the low-sodium health-care salt is 5-10 [mu]m. The low-sodium health-care salt is prepared from the following components in parts by weight: 2 parts of table salt, 0.2-0.3 part of a Chinese gall extract, 0.2-0.3 part of a suaeda salsa extract, 0.7-0.9 part of a shiitake mushroom extract, 0.7-0.9 part of a kelp extract, 1.2-1.5 parts of a tomato extract, 0.8-1 part of dried haws, 1-1.5 parts of cactus pedicle and 0.8-1.2 parts of lemon juice. Various components are added to ordinary table salt, so that the intake of NaCl is effectively reduced under the premise of equal saline taste; besides, the particle diameter of the prepared low-sodium health-care salt is small, so that people can taste clear saline taste when a small dosage of the low-sodium health-care salt is used; and therefore, the low-sodium health-care salt disclosed by the invention is particularly suitable for the patients suffering from the high blood pressure, the patients suffering from the high blood pressure can taste better saline taste, but the risk that the blood pressure increases cannot exist.

The inventors have discovered that both soluble erythropoietin-binding protein and antibodies against the erythropoietin-binding protein, when they are administered to a mammal along with erythropoietin (Epo), prevent or reduce the blood pressure increase normally caused by erythropoietin, while not affecting the hematocrit increase that is the purpose of Epo treatment. The invention provides a method of treating anemia in a mammal involving: administering erythropoietin (Epo) to the mammal; and administering to the mammal an agent selected from a soluble Epo-binding protein (Epo-bp), a recognition protein that binds Epo receptor on an extracellular soluble portion of the Epo receptor, and a combination thereof. The invention also provides a method of reducing hypertension in a mammal receiving Epo, and pharmaceutical compositions containing a soluble Epo-bp and / or a recognition protein that binds Epo receptor on an extracellular soluble portion of the Epo receptor.

The invention relates to a blood-pressure-treating traditional Chinese medicine composition, and specifically relates to a nerve-soothing blood-pressure-reducing traditional Chinese medicine tea. The invention provides the tea aiming at solving a series of health problems caused by increased blood pressure due to higher mental dysfunction caused by fast life pace, increased work pressure, and inappropriate diet and rest. The nerve-soothing blood-pressure-reducing traditional Chinese medicine tea is composed of the raw materials, by weight: 30-120 parts of mulberry leaves, 25-125 parts of hawthorn leaves, 20-100 parts of eucommia leaves, 20-100 parts of Japanese pogodatree flower, 15-75 parts of white chrysanthemum, 10-50 parts of Szechwan lovage rhizome, 10-50 parts of obtuseleaf senna seed, and 10-50 parts of ginkgo leaves. When the nerve-soothing blood-pressure-reducing tea provided by the invention is taken for a long time, human body functioning can be gradually improved. The tea has the functions of human central nervou regulating, fatigue relieving, sleep promoting, body immunity enhancing, human body self-regulation enhancing, and blood pressure fluctuation suppressing.