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Preparing and processing method of prepared aconite slice

A processing method and a technology for making attached tablets, which are applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and antidote, etc., and can solve the problems of changes in ingredients, influence of decoction of medicines, complicated and cumbersome processing methods, etc.

Active Publication Date: 2014-11-26
SICHUAN ACAD OF CHINESE MEDICINE SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It infiltrates the aconite with alkaline water to make the processed product alkaline, which may affect the compatibility of the subsequent traditional Chinese medicine compound and lead to changes in the decoction ingredients of the medicine
Moreover, the processing methods reported in these literatures are all soaking / infiltrating the dried aconite in water or alkaline water, then heating and drying, and the processing methods are relatively complicated and cumbersome.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Take the fresh raw aconite, remove the mother roots, fibrous roots and silt according to the method prescribed in the pharmacopoeia (the same below), wash, slice, and dry, that is, the raw aconite. The raw attachment sheet is placed in a dry heat sterilization cabinet, and dried at a high temperature of 200°C for 30 minutes to obtain the attachment sheet of the present invention.

Embodiment 2

[0018] Take fresh aconite, remove the mother roots, fibrous roots and silt, wash, slice, directly place in a humid heat sterilization cabinet, steam at 105±3 ℃ humid heat and high pressure for 60 min, and then dry to obtain the present invention The production attached film.

Embodiment 3

[0020] Take fresh raw aconite, remove the mother roots, fibrous roots and silt, wash, slice, and dry. Take the raw attachments, place them in a dry heat sterilizer, and bake them at 240°C for 15 minutes in dry heat to obtain the attachments of the present invention.

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PUM

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Abstract

The invention relates to a preparing and processing method of a prepared aconite slice. The preparing and processing method comprises the following steps of: carrying out heat treatment on a raw aconite slice at 102-240 DEG C for 0.25-2 hours; then drying to obtain the prepared aconite slice, wherein the heat treatment is preferably carried out under the damp and hot condition with water vapors at 102-108 DEG C for 0.5-2 hours or carried out under a 140-240 DEG C dry and hot condition for 0.25-1 hour. Experiments indicate that the prepared aconite slice prepared and processed through the method disclosed by the invention can outstandingly reduce the content of a toxic component, namely diester-type alkaloid, and can also retain the dopamine hydrochloride and salsolinol which are the cardiotonic and blood pressure increasing effective components of monoester-type alkaloid and aconite, thereby ensuring the exertion of the recuperating, rescuing, cardiotonic and blood pressure increasing drug effect of the prepared aconite slice.

Description

technical field [0001] The invention relates to a kind of decoction pieces of traditional Chinese medicine, in particular to a processing method for making Fu-pian. Background technique [0002] Aconite is a plant of Ranunculaceae ( Aconitum carmichaeli Debx ) is a processed product of Zigen, which is a well-known and definite Chinese herbal medicine. Aconite is pungent, sweet, very hot, poisonous, and has the effects of returning to the yang and rescuing the adversity, nourishing fire and supporting yang, dispelling cold and relieving pain. Aconite is not only a representative of toxic traditional Chinese medicine, but also a commonly used traditional Chinese medicine in clinic. Physicians of all dynasties paid special attention to the research on the processing and attenuating technology of aconite. [0003] Studies have shown that the active ingredients and toxic ingredients in aconite are alkaloids. The main toxic components are diester alkaloids, so the purpose of p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/714A61P39/00A61P29/00A61K125/00
Inventor 陈燕唐小龙黄志芳刘云华刘玉红刘倩伶易进海
Owner SICHUAN ACAD OF CHINESE MEDICINE SCI
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