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32 results about "Blood glucose decreased" patented technology

Substituted benzylthiazolidine-2, 4-dione derivatives

The invention provides novel substituted benzylthiazolidine-2,4-dione derivatives that bind to receptor to activate as ligands of human peroxisome proliferator-activated receptor (PPAR) and exhibit blood glucose-decreasing action and lipid-decreasing action, and processes for preparing them.It relates to substituted benzylthiazolidine-2,4-dione derivatives represented by the general formula (1)[wherein the bond mode of A denotes -CH2CONH-, -NHCONH-, -CH2CH2CO- or -NHCOCH2-, and B denotes a lower alkyl group with carbon atoms of 1 to 4, lower alkoxy group with carbon atoms of 1 to 3, halogen atom, trifluoromethyl group, trifluoromethoxy group, phenyl group which is unsubstituted or may have substituents, phenoxy group which is unsubstituted or may have substituents or benzyloxy group which is unsubstituted or may have substituents], their medicinally acceptable salts, their hydrates and processes for preparing them.
Owner:KYORIN PHARMA CO LTD

Preparation method and application of physiologically active notoginseng polysaccharide

The invention provides a preparation method and application of physiologically active notoginseng polysaccharide. The method comprises the steps of refining and purifying by applying resin column chromatography, activated carbon and membrane separation and purification technology, and the like, so as to obtain the notoginseng polysaccharide. The notoginseng polysaccharide obtained by the preparation method provided by the invention has the characteristics of low protein, heavy metal and ash contents and stable quality, has the physiological activities of immunity regulation, liver injury protection, blood glucose decrease, tumor resisting and the like, and can be used singly or combined as raw materials for natural medicines and health products. The preparation method of the notoginseng polysaccharide, provided by the invention, is simple to operate, applicable for industrial production and low in cost and reaches the purposes of energy saving and consumption reduction and realizing comprehensive development and sustainable utilization of the rare Chinese traditional medicine, namely, notoginseng.
Owner:YUXI WINHEY BIO TECH

Method and device utilizing insulin delivery protocols

ActiveUS9492608B2Reduce damaging sequelaConstant blood sugar levelDrug and medicationsPressure infusionInsulin pumpD-Glucose
A method of infusing liquid medicaments including insulin via an insulin pump, includes identifying an insulin delivery protocol associated with ingestion of carbohydrates wherein the insulin delivery protocol is likely to lead to a postprandial drop in blood glucose to a level below a basal level, then proposing at least one alternative insulin delivery protocol to inhibit the postprandial drop in blood glucose by delivering a metered amount of insulin that is appropriate to facilitate the metabolism of the carbohydrates without the postprandial blood glucose level drop. The invention further includes querying the patient as to whether to apply the alternative insulin delivery protocol, receiving instructions from the patient in response to the query, and applying the alternative insulin delivery protocol following receiving instructions from the patient to apply the alternative insulin delivery protocol.
Owner:TANDEM DIABETES CARE INC

Health-care food for assisting blood glucose decreasing and preparation method of granule and capsule thereof

The invention discloses health-care food for assisting blood glucose decreasing. The main functional components of the health-care food are three or more than three types of the following raw materials: kelp or kelp extract, potassium alginate (low molecular weight potassium alginate), rhizoma dioscoreae or rhizoma dioscoreae extract, lycium Chinense miller or lycium Chinense miller extract, radix puerariae or radix puerariae extract, folium mori or folium mori extract, rhizoma polygonati odorati extract, momordica charantia extract, cyclocarya paliurus leaf, corn stigma, rhizoma polygonati, radix astragali seu hedysari, radix notoginseng or radix notoginseng extract, rhodiola rosea or rhodiola rosea extract, inulin and citrus fiber powder. A preparation method of the health-care food for assisting the blood glucose decreasing comprises the following steps of 1, crushing and screening; 2, weighing; 3, mixing and stirring. The health-care food for assisting the blood glucose decreasing has the advantages that the effect of assisting blood glucose decreasing is obvious, the safety is good, any side effect is avoided, and complications and side effects caused by long-time administration of western blood glucose decreasing medicines are avoided; the administration is convenient, and the carrying is easy; the action mechanism is clear, the economic and practical effects are realized, and the application range is wide.
Owner:DALIAN YAWEITE BIOTECH

Application of acanthopanax trifoliatus polysaccharide in preparing medicine for treating diabetes

The invention discloses an application of acanthopanax trifoliatus polysaccharide in preparing a medicine for treating diabetes. An experiment proves that acanthopanax trifoliatus polysaccharide can increase the weight of a micemouse with the diabetes obviously, and the recovery capability of acanthopanax trifoliatus polysaccharide on the weight approximates to that of metformin. The experiment also proves that acanthopanax trifoliatus polysaccharide has a better blood glucose decreasing effect, does not affect blood glucose of a normal mouse, and has an obvious recovery effect on the blood glucose of the mouse with the diabetes; and a treatment effect of a high dose group most approximates to that of a contrast medicine, namely the metformin. Acanthopanax trifoliatus is an all-natural plant; the medicine resistance of the traditional Chinese medicine is generally lower; acanthopanax trifoliatus plays an important role during diabetes treatment; a side effect brought by western medicines can be reduced; a stem of acanthopanax trifoliatus contains highest-content polysaccharide; and acanthopanax trifoliatus has the advantage of low cost, therefore, the development of a glucose decreasing effect of acanthopanax trifoliatus has a very high economic value.
Owner:迪芬娜健康产业(深圳)集团有限公司

Method for making blood-glucose-decreasing rice by adopting steam heating cooking utensil

The invention discloses a method for making blood-glucose-decreasing rice by adopting a steam heating cooking utensil. The steam heating cooking utensil comprises a pot and a steam generator. The method for making the blood-glucose-decreasing rice comprises the following steps: (1) a starch release stage, namely, introducing steam into the pot through the steam generator, and heating a rice-watermixture in the pot, so that starch in rice grains separate to water; (2) a water draining stage, namely, carrying out rice-water separation in the pot; and (3) a steaming stage, namely, enabling the steam generator to introduce steam to the pot so that the rice is steamed. According to the method, the high-temperature steam heats the rice-water mixture at the starch release stage, so that the temperature of the rice-water mixture is improved, then starch on the surfaces of and inside the rice grains can rapidly release to water, after the water draining stage, water rich in starch is drained out of the cooking cavity, then the rice is steamed through the high-temperature steam, and therefore, while the mouthfeel of the rice is guaranteed, the content of starch in the rice is greatly reduced.
Owner:HONGYANG HOME APPLIANCES

Health-care medicine with blood glucose decrease effect and preparation method thereof

InactiveCN103520527ATo achieve the role of auxiliary hypoglycemicQuality is easy to controlMetabolism disorderCapsule deliverySide effectBitter gourd
The invention discloses health-care medicine with a blood glucose decrease effect and a preparation method thereof. The health-care medicine comprises the components as follows: 10-15 parts of astragalus, 5-10 parts of kudzu vine roots, 3-8 parts of corn stigma, 3-5 parts of rhizoma anemarrhenae, 3-5 parts of dogwood, 5-8 parts of bitter gourd, 3-5 parts of lyceum barbarum, 3-6 parts of Chinese yarn and 3-5 parts of coptis chinensis. The preparation method of the health-care medicine with the blood glucose decrease effect comprises the steps as follows: washing raw materials including the astragalus, the kudzu vine roots, the corn stigma, the rhizoma anemarrhenae, the dogwood, the bitter gourd, the lyceum barbarum, the Chinese yarn and the coptis chinensis respectively, placing the raw materials at a room temperature for 1-2h, then drying and crushing the raw materials respectively, mixing powder for 1-2h, filling capsules with the powder, performing screening, polishing and packing, and finally putting the medicine in storage after inspection. The health-care medicine has the benefits as follows: the health-care medicine can assist to decrease blood glucose, has no side effects or adverse reactions, and is safe, stable and controllable in quality.
Owner:沙学

Phellinus igniarius polyose and traditional Chinese medicine compound blood-glucose lowering oral liquid and preparation method thereof

The invention discloses phellinus igniarius polyose and traditional Chinese medicine compound blood-glucose lowering oral liquid and a preparation method thereof. The preparation method comprises the following steps: performing giant fungus grass solid fermentation by taking phellinus igniarius liquid fungus as a primary fungus, so as to obtain a great amount of phellinus igniarius hypha; extracting phellinus igniarius polyose by adopting a hot water extraction method, removing impurities, carrying out alcohol precipitation, concentrating and freeze drying to obtain polyose powder; finally, mixing the polyose powder with a traditional Chinese medicine compound concentrated solution to prepare compounds with different doses. According to the invention, the technology is simple and convenient to operate, and is low in cost and price, safe and reliable, and suitable for the industrial large-scale production; the pharmacodynamics experiment on the phellinus igniarius polyose and traditional Chinese medicine compound blood-glucose lowering compound shows that the blood-glucose descending rate of a high dose group can reach up to 44.62%, so that the phellinus igniarius polyose and traditional Chinese medicine compound blood-glucose lowering oral liquid has strong blood-glucose lowering effect.
Owner:福州市惠达天下生物科技有限公司

Spleen invigorating and blood-glucose decreasing health-protection tea for middle and old aged people to drink

The invention relates to spleen invigorating and blood-glucose decreasing health-protection tea for middle and old aged people to drink, which is characterized by comprising the following main components: 30g of raw radix astragali, 15g of radix codonopsitis, 15g of rhizoma atractylodis macrocephalae, 15g of tuckahoe, 15g of Chinese yam, 30g of sealwort, 15g of kudzuvine root, 15g of pollen, 15g of dwarf lilyturf root, 9g of Chinese wolfberry, 9g of dogwood fruit, 15g of salvia miltiorrhiza, 9g of membrane of chicken gizzard, 6g of rhizoma coptidis and other Chinese medical herbs. A method for preparing the spleen invigorating and blood-glucose decreasing health-protection tea comprises the following steps: all the Chinese medical herbs are put in a container to be decocted on slow fire for 25 min, and dregs of a decoction are filtered to obtain the decoction of 200 ml. The lukewarm decoction is taken in the morning and in the evening every day. The preparation is prepared by the Chinese medical herbs, thereby preserving the medicine property of invigorating the spleen, tonifying the Qi, nolurishihg the Yin, promoting the production of body fluid, decreasing the blood glucose and deswelling, achieving the purpose of protecting health and having no side effect.
Owner:李彦奎

Buckwheat flour deep-fried dough stick and cooking method thereof

The invention discloses a buckwheat flour deep-fried dough stick which is characterized by being cooked by the following raw materials in parts by weight: 500-600 parts of flour, 5-6 parts of salt, 100-120 parts of corn flour, 100-120 parts of buckwheat flour, 50-60 parts of glutinous rice flour, 10-15 parts of milk powder, 20-30 parts of shiitake mushroom, 5-8 parts of houttuynia cordata, 3-5 parts of cortex moutan, 10-12 parts of radix rehmanniae, 3-5 parts of perilla leaves, 3-5 parts of radix angelicae, 3-5 parts of broadleaf holly leaves, 2-3 parts of lotus leaves, 3-5 parts of codonopsis pilosula, 3-5 parts of fructus ziziphi jujubae leaves, 3-5 parts of polyalthia root, 1-2 parts of hance brandisia herb, and an appropriate amount of yeast, baking soda and water. According to the formula, buckwheat is added, and can assist in decreasing blood glucose; the milk powder can improve a taste of the deep-fried dough stick; the radix rehmanniae has a blood glucose decreasing effect; the perilla leaves and the codonopsis pilosula can strengthen a stomach and promote digestion; and the buckwheat flour deep-fried dough stick can improve an immunologic function and facilitates human health.
Owner:WUHU XIANGRONG FOOD

Substituted benzylthiazolidine-2,4-dione derivatives

The invention provides novel substituted benzylthiazolidine-2,4-dione derivatives which increase the transactivation of receptor as a ligand of human peroxisome proliferator-activated receptor (PPAR) and exhibit the blood glucose-decreasing action and lipid-decreasing action, and a process for preparing them.The invention relates to substituted benzylthiazolidine-2,4-dione derivatives represented by the general formula (1)[wherein A denotes a pyridyl group or cyclohexyl group], their medicinally acceptable salts, their hydrates and a process for preparing them.
Owner:KYORIN PHARMA CO LTD

Substituted benzylthiazolidine-2, 4-dione derivatives

The invention provides novel substituted benzylthiazolidine-2,4-dione derivatives which increase the transactivation action of receptor as a ligand of human peroxisome proliferator-activated receptor (PPAR) and exhibit the blood glucose-decreasing action and lipid-decreasing action, and a process for preparing them.The invention relates to substituted benzylthiazolidine-2,4-dione derivatives represented by the general formula (1)[wherein A denotes a phenyl group which is unsubstituted or may have substituents, phenoxy group which is unsubstituted or may have substituents or benzyloxy group which is unsubstituted or may have substituents], their medicinally acceptable salts, their hydrates and a process for preparing them.
Owner:KYORIN PHARMA CO LTD

Polysaccharide fragment of Dendrobium officinale and extraction method thereof

The present invention relates to the technical field of Dendrobium officinale, and in particular relates to a polysaccharide fragment of Dendrobium officinale and an extraction method thereof, the extraction methods includes water extraction, deproteinization, enzymatic modification, purification, drying and other steps, the extracted polysaccharide fragment comprises six monosaccharides such as D-glucose, D-mannose, D-galactose, L-rhamnose, D-xylose and D-fucose, experiments prove that the polysaccharide fragment of Dendrobium officinale has non-stimulating effect on insulin secretion of normal mice has higher safety, compared with use of glipizide hypoglycemic drugs, blood glucose decreased rate and glucagon rising rate by use of the polysaccharide fragment of Dendrobium officinale all good, and the polysaccharide fragment of Dendrobium officinale has a significant hypoglycemic effect on a SD rat with streptozotocin induced diabetes.
Owner:连南瑶族自治县欣胜堂生物科技有限公司

Nano inclusion compound capable of reducing blood glucose and preparation method of nano inclusion compound

The invention discloses a nano inclusion compound capable of reducing blood glucose and a preparation method of the nano inclusion compound and belongs to the technical field of functional food. The nano inclusion compound is prepared from a boletus frondosus dicks extract, dietary fiber and protein peptide by acid dissolution and addition of alkali liquor for neutralization. Raw materials of thenano inclusion compound are safe and reasonable in compatibility. Besides, the preparation method and process of the inclusion compound are simple to operate and good in repeatability, and obtained granules or tablets have attractive appearance, high wear resistance and good formability. Experiments prove that the inclusion compound has effects of gastric acid resistance and slow release, in a hyperglycemia mouse model, after 2 weeks of intragastric administration, the fasting blood-glucose decrease rate of the model is 39.5%, the functions of pancreatic beta cells can be effectively improved,and blood glucose can be reduced. The formula has excellent taste, can be used as a raw material of solid drinks or functional food and is widely applicable to diabetics.
Owner:JIANGNAN UNIV

Coffee with blood-glucose-decreasing and health-preserving functions

InactiveCN105876041AAntioxidantWith protective heartCoffee substitutesSucroseLife quality
The invention discloses coffee with blood-glucose-decreasing and health-preserving functions. The coffee with the blood-glucose-decreasing and health-preserving functions comprises the following raw-material components in percentage by weight: 15-25% of instant coffee powder, 5-20% of acanthopanan trifoliatus polysaccharide extract, 15-30% of milk powder, 2-10% of non-dairy cream and 25-40% of sugar powder. The acanthopanan trifoliatus polysaccharide extract in the coffee has the functions of dispelling wind, dispersing dampness, clearing away heat, detoxifying, relaxing muscles and joints, promoting blood circulation and so on; the instant coffee powder is rich in substances such as proteins, fat, sucrose, starch, caffeine and so on, and has the effects of resisting oxidation, protecting the heart, strengthening the bones and the muscles, benefiting the waist and the knees, promoting appetite and digestion, lowering blood lipid, removing food retention, promoting defecation and urination, dispersing dampness, promoting blood circulation, removing blood stasis, subduing liver-wind, arresting convulsion and so on; moreover, the instant coffee powder is capable of promoting metabolism functions and eliminating fatigue. Thus, the coffee disclosed by the invention has obvious healthcare functions of reducing blood glucose due to organic combination of the acanthopanan trifoliatus polysaccharide extract with the instant coffee powder; moreover, the coffee is balanced in nutrition, and is capable of effectively improving life qualities of the people.
Owner:王永福

Ammonia Metabolism Promoter

A material which has excellent ammonia metabolism improving effect and is effective for endurance enhancement, anti-fatigue or the like is provided. An ammonia metabolism promoting agent, comprising catechins and ornithine as active ingredients. An endurance enhancing agent, comprising catechins and ornithine as active ingredients. An anti-fatigue agent, comprising catechins and ornithine as active ingredients. An agent for suppressing a reduction in blood glucose level by exercise, comprising catechins and ornithine as active ingredients. An agent for promoting recovery from reduced blood glucose level by exercise, comprising catechins and ornithine as active ingredients. An agent for suppressing a reduction in muscle glycogen by exercise, comprising catechins and ornithine as active ingredients. A muscle endurance enhancing agent, comprising catechins and ornithine as active ingredients. An agent for preventing or ameliorating hyperammonemia, hepatic encephalopathy or chronic fatigue syndrome, comprising catechins and ornithine as active ingredients.
Owner:KAO CORP

Intelligent blood glucose monitoring device for developed glucose regulation of 18F-FDG PET viable myocardium

The invention discloses an intelligent blood glucose monitoring device for developed glucose regulation of a 18F-FDG PET viable myocardium. The intelligent blood glucose monitoring device comprises aninformation acquisition module, wherein the information acquisition module is used for acquiring blood glucose information on a subject; an electronic transmission module, wherein the electronic transmission module is used for generating a blood glucose-time variation curve for the acquired blood glucose information on the subject; a display module, wherein the display module is used for displaying the blood glucose-time variation curve generated by the electronic transmission module; and a threshold comparison module, wherein the threshold comparison module is used for setting a dangerous threshold of hypoglycemia of the subject. According to the intelligent blood glucose monitoring device, blood glucose conditions of a sufferer are concerned in real time in a whole glucose loading process, insulin of a certain dosage is offered when the blood glucose rises obviously and is greater than the threshold, then, 18F-FDG is injected when a slope coefficient of a blood glucose descending curve is maximum, thus, the intake of glucose by viable myocardium is maneuvered to the maximum, the image quality is improved, and successful development is ensured; and pain and discomfort of the sufferer caused by repeated blood-glucose-measurement pricking in a short time can be avoided, and patient compliance is improved.
Owner:THE FIRST PEOPLES HOSPITAL OF CHANGZHOU

A kind of mulberry leaf crisp food that assists in lowering blood sugar

A mulberry leaf crisp chip food assisting blood glucose reducing is disclosed. The food is characterized in that the food is prepared by fully stirring mulberry leaf powder prepared from mulberry leaves and a traditional Chinese medicine extract prepared from tartary buckwheat, bitter gourd and grosvenor momordica fruit, performing compression molding by adopting a tabletting device, roasting in a furnace, cooling, and packaging with nitrogen being filled. According to a technical scheme of the food, the fresh mulberry leaves, the tartary buckwheat, the bitter gourd and the grosvenor momordica fruit are adopted as raw materials, and the purely natural crisp chip food which is natural, nutritious, convenient and good in taste is prepared by treatment determination based on syndrome differentiation in traditional Chinese medicine and modern medicine. The food has effects of tonifying yin, promoting the secretion of saliva, quenching thirst, moistening dryness and tonifying qi, and plays a role of regulating and tonifying liver, kidney, spleen, lung and stomach. When functions of internal organs of a person recover, the blood glucose decreases naturally, and body constitution is improved to different degrees. The food can assist blood glucose reducing and prevent diabetic complication. An objective of assisting blood glucose reducing can be achieved if a person eats the food often.
Owner:威海紫光生物科技开发有限公司

Instant granules for consumers frequently using electronic products and technology thereof

The invention relates to instant granules for consumers frequently using electronic products and a technology thereof. The technology comprises the following steps of crushing at low temperature by a high-speed impact type crusher, centrifuging and separating by a super-speed centrifuging machine, concentrating and drying, and granulating by a high-speed centrifuging machine. Compared with the prior art, the technology has the advantages that an eyesight improving agent, a spot eliminating agent, a Qi regulating agent, a depression resolving agent, a restlessness relieving agent, a digestion promoting agent, a blood glucose decreasing agent and a vitamin agent are integrated according to a reasonable proportional ratio, the instant granules are suitable for the consumers who frequently use the electronic products, the functions of improving eyesight is realized, the upset, impatience, depression, poor digestion, high blood glucose and the like of the consumers can be prevented when the consumers use the electronic products for a long time, and the spot and other conditions of face skin caused by screen radiation are effectively regulated when the consumers face the electronic product screen for a long time; by adding a fruit flavor agent into the components, the mouth feel of the consumer in drinking is improved, and the market prospect is good.
Owner:李晓光

Phellinus igniarius polyose and traditional Chinese medicine compound blood-glucose lowering oral liquid and preparation method thereof

The invention discloses phellinus igniarius polyose and traditional Chinese medicine compound blood-glucose lowering oral liquid and a preparation method thereof. The preparation method comprises the following steps: performing giant fungus grass solid fermentation by taking phellinus igniarius liquid fungus as a primary fungus, so as to obtain a great amount of phellinus igniarius hypha; extracting phellinus igniarius polyose by adopting a hot water extraction method, removing impurities, carrying out alcohol precipitation, concentrating and freeze drying to obtain polyose powder; finally, mixing the polyose powder with a traditional Chinese medicine compound concentrated solution to prepare compounds with different doses. According to the invention, the technology is simple and convenient to operate, and is low in cost and price, safe and reliable, and suitable for the industrial large-scale production; the pharmacodynamics experiment on the phellinus igniarius polyose and traditional Chinese medicine compound blood-glucose lowering compound shows that the blood-glucose descending rate of a high dose group can reach up to 44.62%, so that the phellinus igniarius polyose and traditional Chinese medicine compound blood-glucose lowering oral liquid has strong blood-glucose lowering effect.
Owner:福州市惠达天下生物科技有限公司

Liraglutide nasal drops for the treatment of type 2 diabetes

The invention discloses a liraglutide nose drops for treating type II diabetes, which is prepared from liraglutide, Solutol HS15 according to a conventional preparation method. The contrast pharmacological experiment with liraglutide provides that the blood sugar decrease rate of a mice is 76.7%; the sugar reducing effect of nasal delivery is obviously better than liraglutide, and the nose drops can be used for a long time, and is safe, effective, and convenient to use, and able to reduce the patient's pain; moreover, the liraglutide nose drops can be applied to treat type II diabetes and suitable for long-term supply.
Owner:SHAANXI HUIKANG BIO TECH CO LTD

Blood-glucose-decreasing traditional Chinese medicine granules

The invention discloses blood-glucose-decreasing traditional Chinese medicine granules which comprise the following components: cortex lycii radicis, Chinese yam, poria cocos, polygonum multiflorum, semen cassia, astragalus, hawthorns, rhizoma anemarrhenae, schisandra chinensis, coptis chinensis, radix scrophulariae, radix polygonati officinalis, radix puerariae, rhizoma atractylodis, rhizoma alismatis, hairyvein agrimony, platycodon grandiflorum and ingredients. The blood-glucose-decreasing traditional Chinese medicine granules disclosed by the invention have the advantages of being exact indrug effect, fast in efficacy and zero in side effect and can achieve effects of effectively reducing absorption of sugar, regulating the blood glucose content and decreasing the blood glucose. The blood-glucose-decreasing traditional Chinese medicine granules disclosed by the invention are widely applied to hyperglycemia patients.
Owner:大同县科学技术开发交流服务中心

A new type of sulfonic acid derivative, its preparation method and its use as medicine

The invention relates to a novel sulphone acid derivative show in a formula (I), a preparation method thereof and application of a medicine composition containing the derivative in preparing medicines for treating diabetes and metabolic syndrome. The sulphone acid derivative has excellent in-vivo blood glucose decreasing activity, and can be used for preventing or treating diabetes. (The formula is shown in the description).
Owner:CHINA PHARM UNIV

Ganoerma lucidum capusule for reducing blood sugar

The invention discloses a prepared traditional Chinese medicinal preparation for treating diabetes, wherein the constituents include ganoderma lucidum, ginseng, achyranthes and cyathula root, haw, gentian root, goldthread root, corktree bark, cogongrass rhizome, wild jujuba seeds, white atractylodes rhizome, Chinese angelica root, fleece-flower root, prepared rehmannia root, dipsacus root, broomrape, wolferry fruit, fragrant solomonseal rhizome, Siberian solomonseal rhizome, raspberry, schisandra fruit, bitter cardamon and spatholobus stem.
Owner:朱远志

Composite preparation for preventing or treating metabolic diseases

PendingCN111423408AExcellent blood sugar lowering effectPowder deliveryOrganic chemistryLow insulinThiazolidinedione
The present invention relates to a pharmaceutical composition for preventing or treating metabolic diseases, in which a novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative and at least another active ingredient, which is selected from the group consisting of dipeptidyl peptidase-4 (DPPIV) inhibitor-based, sulfonylurea-based, thiazolidinedione (TZD)-based, biguanide-based, and sodium / glucose cotransporter 2 (SGLT2) inhibitor-based drugs, may be administered in combination or in the form of a composite preparation. The use of the composition of the present invention can provide a remarkablyexcellent blood sugar reducing effect in various animal diabetic disease models, and the composition of the present invention can be favorably used as a pharmaceutical composition for preventing or treating metabolic diseases, such as obesity, diabetes type I, diabetes type II, glucose intolerance symptoms, insulin resistance symptoms, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia, and syndrome X.
Owner:HYUNDAI PHARMA

Drug for treating diabetes

InactiveCN105943616ADefinitive role in the treatment of diabetesGood effectMetabolism disorderPlant ingredientsAdemetionineBlood glucose decreased
The invention discloses a drug for treating diabetes. The drug is prepared by evenly mixing 0.3-99.7 parts by weight of industrial hemp seed extract and 99.7-0.3 parts by weight of industrial cannabinoid. It is proved through experiments that the drug can obviously decrease the blood glucose value of an animal with the diabetes, improve abnormal glucose tolerance, improve abnormal lipid metabolism, has an inhibiting effect on blood glucose rise of a normal animal after orally taking glucose and has no obvious influence on the blood glucose of the normal animal. Drug treatment clinic observation is conducted on 100 patients with type-II diabetes, active ingredients of the drug have an effect of lowering blood glucose, and the total effective rate reaches 95%. The drug is safe in medication and definite in blood glucose decreasing efficacy.
Owner:云南瑞酚生物科技有限公司

Traditional Chinese medicine composition for preventing and treating diabetic complications and preparation method of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for preventing and treating diabetic complications. The traditional Chinese medicine composition for preventing and treating diabeticcomplications comprises the following raw materials: in parts by weight, folium ginkgo, radix salviae miltiorrhizae, fructus schisandrae, hirudo, radix scutellariae, radix astragali, radix gardeniae,radix et rhizoma rhei, radix angelica sinensis, fructus lycii, coptidis rhizoma, common yam rhizome, mulberry twig, myrrh, lignum aquilariae resinatum and colophony. Through the traditional Chinese medicine composition, balance of yin and yang can be achieved through heat clearing and lung moistening, saliva regenerating and thirst quenching, stomach clearing and yin nourishing, spleen nourishingand stomach invigorating and yin and kidney nourishing, the functions of lungs, spleens, kidneys and pancreas can be restored, the symptoms can be eliminated, and the blood sugar is reduced.
Owner:贵州中医药大学第二附属医院

Exenatide Nasal Drops for Type Ⅱ Diabetes

An exenatide nasal drop for treating type II diabetes is prepared from exenatide and Solutol HS15 according to a conventional preparation method. The present invention has been compared with exenatide in drug efficacy experiments, which proves that the blood sugar reduction rate of mice is 60.1%, and the hypoglycemic effect of nasal administration is significantly better than that of exenatide, and can be used for a long time, safe, effective, It is convenient to use, can reduce pain of patients, can be used for treating type II diabetes, and is suitable for long-term administration.
Owner:SHAANXI HUIKANG BIO TECH CO LTD

Preparation method and application of physiologically active notoginseng polysaccharide

The invention provides a preparation method and application of physiologically active notoginseng polysaccharide. The method comprises the steps of refining and purifying by applying resin column chromatography, activated carbon and membrane separation and purification technology, and the like, so as to obtain the notoginseng polysaccharide. The notoginseng polysaccharide obtained by the preparation method provided by the invention has the characteristics of low protein, heavy metal and ash contents and stable quality, has the physiological activities of immunity regulation, liver injury protection, blood glucose decrease, tumor resisting and the like, and can be used singly or combined as raw materials for natural medicines and health products. The preparation method of the notoginseng polysaccharide, provided by the invention, is simple to operate, applicable for industrial production and low in cost and reaches the purposes of energy saving and consumption reduction and realizing comprehensive development and sustainable utilization of the rare Chinese traditional medicine, namely, notoginseng.
Owner:YUXI WINHEY BIO TECH
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