136 results about "Blood sugar monitoring" patented technology

A system and method for continuous non-invasive glucose monitoring is disclosed. According to one embodiment of the present invention, the method includes the steps of (1) contacting a remote device to an area of biological membrane having a permeability level, the remote device comprising a sensor and a transmitter; (2) extracting the at least one analyte through and out of the area of biological membrane and into the sensor; (3) generating an electrical signal representative of a level of the at least one analyte; (4) transmitting the electrical signal to a base device; (5) processing the electrical signal to determine the level of the at least one analyte; and (6) displaying the level of the at least one analyte in real time. The system includes a remote device that includes a sensor that generates an electrical signal representative of the concentration of the at least one analyte; and a transmitter that transmits the electrical signal. The system further includes a base device that includes a receiver that receives the electrical signal; a processor that processes the electrical signal; and a display that displays the processed signal in real time.

A glucose monitoring kit for storing, carrying and using a blood glucose monitoring system, which includes a meter, a container for storing test strips and at least one sampler, is configured with case having two halves pivotal relative to one another, and a retention system. The retention system includes a plurality of clips arranged so that the first clip extends along the central region of the case between the two halves and second and third clips coupled to one of the halves. At least one of the first, second and third clips is made from hard polymeric material and configured to removably receive the meter so that the meter can be used by the operator of the monitoring system while being retained in the at least one clip

Disclosed is a method and the resulting product thereof comprising a solid light-conducting fiber with a point of attachment and having a textured surface site consisting a textured distal end prepared by being placed in a vacuum and then subjected to directed hyperthermal beams comprising oxygen ions or atoms. The textured distal end comprises cones or pillars that are spaced upon from each other by less than 1 micron and are extremely suitable to prevent cellular components of blood from entering the valleys between the cones or pillars so as to effectively separate the cellular components in the blood from interfering with optical sensing of the glucose concentration for diabetic patients.

The invention provides a transdermal analyte sensing device and an installation method thereof. The percutaneous analyte sensing device includes a medical adhesive plaster, a probe base with first, second and third installation structures on it; used for combining the probe body, the probe installer and the emitter. The probe installer includes an instant ejection-recovery mechanism and a release button, which can instantly complete the ejection and recovery actions of the guide needle without manual operation. After the probe body of the present invention is installed, the probe installer can be easily removed, and the transmitter can be easily installed and removed. The transdermal analyte sensing device of the present invention is also provided with a protective cover that can be combined with the probe base and the probe mount. The transdermal analyte sensing device of the present invention is small in size, easy to wear, simple and safe to install and operate, and provides a perfect solution for users to realize continuous blood sugar monitoring by themselves.

The invention relates to a watch-type non-trauma optical acoustic blood sugar monitor. A display screen, a control button, a controller, a cell and a measurement box are arranged in watch-type casing, an acoustic insulating layer, a sound absorption pad, a semiconductor laser tube, a Fourier lens, a light-transparent protection film and a hollow multi-ring array sensor are packaged in the measurement box to form a integrated coaxial confocal structure. The watch-type casing is equipped with a watchband to be wore on wrist of detector, an optical acoustic excitation source and an optical path lens system generate focused laser beam which passes through the hollow multi-ring array sensor and radiates to blood vessel of wrist to realize optical acoustic blood sugar detection of continuous A-type dynamic focusing scan and provide optical acoustic blood sugar results of multiple sites along wrist depth direction. The monitor has advantages of having small structure and simple operation, realizing real-time monitoring of optical acoustic blood sugar, having no trauma when detecting, having no need of blood supply and test paper, and avoiding cross infection and environmental influence.

The invention discloses a separately powered dynamic blood sugar monitoring transmitter, a system and a signal sampling method. The separately powered dynamic blood sugar monitoring transmitter structurally comprises a transmitter body and a sensor base device. The sensor base device is divided into a base and adhesive tape, a battery jar and a groove are formed in the base, a battery is arrangedin the battery jar, a rotating seat is installed in the groove, one side of the rotating seat is hinged in the groove, a silica gel seat is arranged in the rotating seat, a pair of conductive rubbersis arranged in the silica gel seat, the transmitter body comprises a circuit board assembly, and the circuit board assembly is provided with four conductive pins which can be in contact with a positive electrode, a negative electrode and the two conductive rubbers. Compared with the prior art, the button battery can be separated from the transmitter body and integrated with a sensor, when the transmitter is not used, the transmitter is not installed on a sensor base, so that the transmitter is in a power-off state, power of the button battery is not consumed; when the transmitter is used, thetransmitter is buckled on the sensor base, and the battery on the sensor base is electrically connected to the transmitter for power supply.

The invention relates to an extensible human parameter monitoring and recording system, comprising a personal monitoring terminal, a remote server, a cloud server, a remote analysis server, a health data server, a remote alarm monitoring module and a remote consultation module, wherein the personal monitoring terminal is used for acquiring body related data of a user wearing the system, and specifically comprises a sleep monitoring module, a dynamic ECG (Electrocardiograph) module, a dynamic blood pressure module, a fetal heart monitoring module, a body temperature monitoring module, a blood oxygen monitoring module and a blood sugar monitoring module; the remote server is used for receiving monitoring parameters of the personal monitoring terminal; the cloud server is used for receiving and analyzing data of the remote server; the remote analysis server is used for analyzing the statistical result of the cloud server and improving the living habit of a user; the health data server is used for storing testing data of a user; the remote alarm monitoring module is used for monitoring the health parameters of the user, and when an unusual condition occurs suddenly, a first-aid unit can be informed; the remote consultation module is used for sending the data of the user to relevant specialized personnel, and providing online consulting services. All functional modules are mutually compatible, the use cost is reduced, the relevant data can be deeply analyzed, a real-time monitoring and consultation service can be provided, and great conveniences are brought to the user.

The invention provides blood sugar real-time monitoring system and method, a blood sugar detection device and a mobile phone terminal, wherein the blood sugar real-time monitoring system comprises theblood sugar detection device and a blood sugar monitoring centre server. The blood sugar detection device is used for collecting blood sugar data of users, uploading the collected blood sugar data tothe blood sugar monitoring centre server and receiving and displaying diagnosis results returned form the blood sugar monitoring centre server. The blood sugar monitoring centre server is used for receiving the blood sugar data sent by the blood sugar detection device, storing the blood sugar data to a blood sugar information database, analyzing the blood data information stored by the blood sugar information database in specified time, forming diagnosis results and returning the diagnosis results to the blood sugar detection device. The user of the blood sugar real-time monitoring system cancollect the blood sugar data at will and send the blood sugar data to the blood sugar monitoring center server in real time so as to obtain the diagnosis results of the monitoring centre, thereby realizing remote real-time monitoring for patients.

The invention discloses a preparation method and an application of a layered nickel-cobalt hydroxide. ZIF-67 and Ni salt are mixed into an organic solvent at certain proportion and concentration, are heated and refluxed under the condition of magnetic stirring, and are centrifuged and separated, washed, and dried in vacuum to obtain a final product. The preparation method is simple and quick, the material is used to detect glucose, the detection sensitivity is very high, the detection scope is relatively wide, and the material has a great application prospect in the field of blood sugar monitoring.

The invention provides a detection system for expired gas. The detection system comprises an expired gas analyzer and a computer, wherein the expired gas analyzer comprises a mini vacuum pump, a gas chamber, a sensor array, a signal processing circuit and a data acquisition card; the sensor array comprises a gas sensor and an environmental monitoring sensor; the vacuum pump sucks the expired gas or clean air into the gas chamber and is in contact with the sensor array; the signal processing circuit filters responses of the sensors, and transmits the responses to the data acquisition card after amplifying the responses; and the data acquisition card transmits processed responses to the computer after digitizing the processed responses. The system can be used for assisting in analyzing expiration-related physical conditions, such as diagnosis of diabetes, blood sugar monitoring of a diabetic patient, prevention of ketoacidosis, and monitoring of fat consumption in the body building or weight losing process.

The invention discloses a dynamic blood glucose monitor capable of conducting direct monitoring through a mobile phone APP and a control method of the dynamic blood glucose monitor, and relates to wearable equipment used in the field of medical detection and a control method of the wearable equipment. The dynamic blood glucose monitor comprises a wearable blood glucose transmitter, a mobile phoneAPP terminal and a cloud memory which is connected via the mobile phone APP terminal; the blood glucose transmitter is constituted by connecting a blood glucose sensor component and a transmitter component; the mobile phone APP terminal is connected to the blood glucose transmitter via a Bluetooth mode; the mobile phone APP terminal is connected to the cloud memory via a mobile communication network; by pushing blood glucose monitoring data to an authorized user, network sharing of the blood glucose monitoring data is achieved; sports and sleep information of a wearer can be acquired via a three-axis acceleration sensor while continuously acquiring and recording human body blood glucose; recognition and awakening self-rescuing of hypoglycemic coma are offered; the blood glucose monitoringdata is transmitted to intelligent hand-held equipment or other external receiving terminals having wireless transmitting and receiving functions in a wireless transmitting mode; and data display andanalysis as well as far-end alarming and help-seeking services are offered.

The invention discloses a continuous blood sugar monitoring method and device. The continuous blood sugar monitoring method comprises the steps that blood sugar data of at least two users is obtained, a first blood sugar data matrix is formed according to a preset data splicing method, and multiple first blood sugar data input vectors and output data corresponding to the first blood sugar data input vectors respectively are obtained from the first blood sugar data matrix; a machine learning algorithm is adopted to train a preset mathematical model according to the multiple first blood sugar data input vectors and the output data corresponding to the first blood sugar data input vectors respectively to obtain a blood sugar data prediction model; existing blood sugar data of one user to be predicted is obtained, and second blood sugar data input vectors are formed by adopting the preset data splicing method; the second blood sugar data input vectors are input into the blood sugar data prediction model, a blood sugar data prediction value of the user to be predicted after the current moment is obtained, and it is achieved that the blood sugar concentration is predicted by using population blood sugar data.

The invention relates to an online fault detection method of a continuous blood sugar monitoring sensor based on multi-model fusion, which comprises the following steps of: S1, acquiring online CGM monitoring signal data; S2, inputting the acquired on-line CGM monitoring signal data into a multi-model fusion algorithm model to acquire an on-line prediction error; S3, calculating the obtained on-line prediction error and the historical prediction error in combination to obtain the entropy value of the on-line time; S4, comparing the entropy values Ji1 and Ji2 of the online time obtained by calculation with the threshold values Tkl1 and Tkl2 of the current time respectively; if the entropy values Ji1 and Ji2 at the current moment are not all larger than the threshold values Tkl1 and Tkl2 atthe current moment, judging that the current blood sugar monitoring sensor works normally; if the entropy values Ji1 and Ji2 at the current moment are both larger than the threshold values Tkl1 and Tkl2 at the current moment, judging that the current blood sugar monitoring sensor works abnormally. The detection method has the advantage of high detection precision.

The invention provides a skin heating type artificial pancreas which comprises a blood sugar monitoring device, a duct-less insulin pump and a skin heating device, wherein the blood sugar monitoring device is used for monitoring the change of the blood sugar in a human body in real time and outputting a blood sugar value; the blood sugar monitoring device comprises a glucose sensor; the duct-less insulin pump is used for simulating the mode and function of a human pancreas for physiologically secreting insulin; the duct-less insulin pump comprises an insulin reserving hose; the skin heating device is used for heating the skin tissues located in the positions buried with the glucose sensor and / or the insulin reserving hose; and the skin heating device comprises a skin heating film, a temperature rising module, a temperature control module, a heat-insulating module and a temperature detecting module. The skin heating type artificial pancreas provided by the invention is capable of controlling the temperature of the skin of the human body, solving the delay problem between target blood sugar concentration and insulin peak acting time, shortening the insulin peak acting time and reducing the influence on the blood sugar monitoring caused by the temperature change.

The invention provides a monitoring circuit used for a quartz crystal microbalance blood sugar monitoring system. The monitoring circuit comprises a simulative oscillation circuit and a digital frequency detection circuit, the simulative oscillation circuit is used for acquiring realtime resonance frequency signals of a crystal oscillation sensor and comprises a detection module, a reference module, a power source module, a difference frequency circuit and a signal amplifying unit, the digital frequency detection circuit calculates resonance frequency of the crystal oscillation sensor according to three branches of resonance frequency signals received from the simulative oscillation circuit, calculates numerical value of content of specific substance indicated by the resonance frequency according to the resonance frequency of the crystal oscillation sensor and comprises a signal adjusting and clock reference unit, a CPLD (complex programmable logic device) unit and an interface unit.

The present invention discloses a universal non-invasive blood glucose estimation method based on time series analysis, which comprises 5 steps, i.e., data input and preprocessing, features screening, establishment of single-feature model based on time series analysis, multi-feature fusion, and non-invasive blood glucose estimation. During non-invasive blood glucose estimation, new non-invasive test data is inputted, and the blood glucose estimation series is calculated using related feature information obtained through modeling, single-feature model, and multi-feature fusion model. The estimation method provided in the present invention is easy to execute, and can overcome the delay between changes of physiological parameters of human body and changes of blood glucose, and thereby can obtain more accurate non-invasive blood glucose test results. The estimation method is universal and is applicable to different non-invasive blood glucose monitoring methods.

The invention relates to an interactive portable communication apparatus with function of blood sugar real-time monitoring and a blood sugar monitoring method. The invention aims to provide a portable communication apparatus, which can detect the blood sugar value of a patient anytime anywhere and transmit the test result back to a blood sugar monitoring center server, and a blood sugar monitoring method. The technical scheme is as follows: the interactive portable communication apparatus with the function of blood sugar real-time monitoring comprises a communication module, a memory, a wireless local area network module, a Bluetooth module and a display module which are arranged in a common mobile terminal. The invention is characterized in that the apparatus also comprises a detection module and an NFC module. The invention is suitable for all mobile communication terminals.

The invention discloses a wearable real-time dynamic blood sugar monitoring device. The device comprises a wearable dynamic blood sugar monitor and a sensor implanted under the skin, a binding device used for binding the wrist is connected to the left side and the right side of the wearable dynamic blood sugar monitor, a display screen is installed in the middle of the top of the wearable dynamic blood sugar monitor, a reminding device is arranged on the side face of the top of the wearable dynamic blood sugar monitor, an open-source single chip microcomputer, an information transmission device, a data storage device, a power supply and a magnetic induction device are installed on the inner side of the bottom of the wearable dynamic blood sugar monitor, and the open-source single chip microcomputer is installed in the middle of the bottom of the wearable dynamic blood sugar monitor. The wearable real-time dynamic blood sugar monitoring device is convenient to carry, the wearable real-time dynamic blood sugar monitor can be worn through the binding device, carrying is convenient, the wearable real-time dynamic blood sugar monitor can conduct real-time dynamic blood sugar monitoring on a patient conveniently, the patient can be treated in time and adjust the dosage of medication reasonably and conveniently, and by means of the data storage device stored with diet recipes and the reminding device, the patient can be assisted in eating healthily and assisted in adjusting the blood sugar levels.

The invention provides a preprandial insulin dosage individualized decision-making system based on a Gaussian process. The system utilizes an artificial intelligence method to mine information contained in patient blood glucose monitoring and insulin infusion data at the same time, establishes a postprandial blood glucose prediction model conforming to a human body metabolism rule, utilizes a risksensitive optimization control thought to determine the risk sensitivity coefficient in an individualized mode, and uses a Bayesian optimization method to solve the optimization problem, so the safeand effective preprandial insulin dosage can still be determined even under the condition that deviation exists in model prediction, and postprandial blood glucose management is improved. Therefore, in order to improve postprandial blood glucose management, the preprandial insulin dosage individualized decision-making system based on Gaussian process learning risk sensitive control is designed byutilizing historical data of a patient, the system fully excavates information of historical data of blood glucose metabolism of the patient, and the postprandial blood glucose prediction model is established, so subsequent postprandial blood sugar control or postprandial high and low blood sugar early warning can be conveniently implemented.

The invention relates to the field of medical instruments, in particular to a blood-sampling-free type blood sugar monitoring device and a use method of the blood-sampling-free type blood sugar monitoring device. The blood-sampling-free type blood sugar monitoring device comprises a host and a PCB arranged in the host. The PCB is provided with an LCD display screen, a microprocessor, a blood sugar detection circuit, a storage module and a power module, wherein the blood sugar detection circuit, the storage module and the power module are electrically connected with the microprocessor. The blood sugar detection circuit comprises a blood sugar detection module. The PCB is further provided with a human body resistance collecting circuit electrically connected with the microprocessor. The human body resistance collecting circuit comprises a human body resistance collecting module used for detecting the value of resistance between two points of the human skin, and converting a detection result to a blood sugar value through the microprocessor to be displayed on the LCD display screen of the host. The human body blood sugar changes are reflected by testing skin resistance, a traditional mode that blood sampling is needed every time a blood sugar test is carried out is omitted, pains of patients are relieved, and the blood sugar changes can be conveniently mastered in time.

The invention discloses continuous blood sugar monitoring equipment with an abnormal blood sugar probability warning device. The continuous blood sugar monitoring equipment is used for carrying out analysis aiming at a subcutaneous blood sugar measurement signal of a human body, carrying out predictive modeling according to continuous blood sugar monitoring signals, fitting distribution conditions of prediction errors of a prediction method and calculating warning probability of a sampling point of each blood sugar data according to the distribution conditions of the prediction errors. The fluctuation condition in blood sugar of a patient is changed along an external environment, the distribution conditions of the corresponding prediction errors are changed, and therefore, an analytical function of the distribution of the prediction errors needs to be updated online. According to an abnormal blood sugar warning probability method adopted in the equipment, the integral distribution condition of the prediction errors can be adjusted according to the latest prediction error, so that high-low blood sugar warning probability of current blood sugar sampling can be relatively accurately given out. According to the continuous blood sugar monitoring equipment, the high-low blood sugar warning probability of a blood sugar sampling value can be accurately calculated, and the high-low blood sugar warning accuracy can be increased.

The invention provides a preprandial insulin dosage learning optimization decision-making system assisted by expert experience. According to the system, artificial intelligence and expert experience methods are combined, information contained in patient blood sugar monitoring and insulin infusion data is mined at the same time, a safe and effective preprandial insulin dosage can still be determined based on historical data under the condition of few samples, the postprandial blood sugar management is improved, and meanwhile, the system is endowed with abilities of continuous adaptive learning and decision-making performance improvement. Therefore, in order to improve postprandial blood glucose management and utilize a small amount of patient historical data, an expert decision-making assisted preprandial insulin dose individualized learning decision-making system is designed, a model prediction evaluation method is introduced into the system, system decision errors under the condition of few samples are effectively avoided, and the blood glucose metabolism rule of the patient is continuously learned; and meanwhile, an iterative updating thought is further introduced, a postprandial blood sugar management target is determined in a self-adaptive mode, and safe and effective preprandial insulin doses can be rapidly determined under the condition that few samples are used for diabetic patients under different illness conditions.

The invention discloses an implantable hydrogel fiber grating glucose sensor, a preparation method thereof and a measurement system. A biocompatible glucose-sensitive hydrogel material is adopted as a base material, and a mask method is combined to prepare a fiber bragg grating, so that wavelength-dependent glucose detection is realized. The glucose diffuses into a hydrogel network and is specifically combined with a glucose sensitive group, so that the effective refractive index and the period of the fiber bragg grating are changed, and the resonant wavelength drifts. The real-time and quantitative detection of glucose can be realized by detecting the wavelength drift distance of the fiber bragg grating. In addition, in order to eliminate the influence of environment and light source instability factors, the invention provides a measurement system based on double fiber bragg gratings. The hydrogel material fiber bragg grating has soft biomechanical characteristics and excellent biocompatibility, and is suitable for long-term continuous blood glucose monitoring.

The invention relates to a personnel physiological state recognition platform based on race detection. The recognition platform comprises a blood sugar monitoring sub-system, a brain wave monitoring sub-system, a race detection sub-system and an ARM11 processing chip. The blood sugar monitoring sub-system extracts blood sugar parameters of tested personnel on the basis of the detection result of the race detection sub-system. The brain wave monitoring sub-system monitors the brain wave states of the tested personnel. The ARM11 processing chip recognizes the physiological states of the tested personnel on the basis of the monitoring results of the blood sugar monitoring sub-system and the brain wave monitoring sub-system. By means of the personnel physiological state recognition platform, intelligent medical care monitoring can be provided for the tested personnel on the basis of race recognition.

Safe and effective exercise poses a specific set of challenges for subjects diagnosed with diabetes. These challenges include the coordination of exercise with blood glucose monitoring and insulin administration. Failure to coordinate these factors effectively can lead to various pathologies related to aberrant blood glucose levels. Presented herein are methods, systems, algorithms, computer program products, and computer-executable code for exercise guidance and instruction specific to diabetes relief and management. The approaches as disclosed herein can help ameliorate, slow, or reduce a likelihood of developing a diabetic condition.

The invention is applicable to the technical field of medical signal control, and provides an insulin injection equipment control method, device and system. The control method includes the steps: simultaneously establishing communication connection among a monitor, insulin injection equipment and a continuous blood sugar monitoring module; receiving blood sugar data transmitted by the continuous blood sugar monitoring module in real time; extracting control parameters matched with the blood sugar data from a local database by the monitor; transmitting the control parameters to the insulin injection equipment control system by the monitor to control an insulin pump of the insulin injection equipment to finish injection according to the control parameters by the control system. The working efficiency of the insulin injection equipment is improved, accurate and real-time input of the control parameters can be ensured, and injection accuracy of the insulin injection equipment is improved.

The invention relates to the technical field of intelligent equipment, in particular to a wearable intelligent non-invasive blood glucose monitoring device based on a microfluidic technology. The wearable intelligent non-invasive blood glucose monitoring device comprises a device body and an elastic wrist strap, wherein a display module is arranged on the upper surface of the device body, an accommodating cavity is formed in the lower surface of the device body inwards, a microfluidic chip arranged in the accommodating cavity is used for continuously collecting sweat on the surface of the skinin real time for batch storage, and mapping color development is carried out according to the content of glucose in the sweat; and an arranged data acquisition and judgment module is used for collecting a color development image of the microfluidic chip in real time, processing the image, comparing the image with a reference color to obtain a blood glucose value result, and sending the blood glucose value result to the display module for display and output. According to the wearable intelligent non-invasive blood glucose monitoring device, the problems that a trace amount of sweat samples aredifficult to collect and the sweat samples are difficult to store after being obtained are solved, real-time and non-invasive collection and detection of human body blood glucose data can be realized, and the wearable intelligent non-invasive blood glucose monitoring device based on the microfluidic technology is simple and convenient to operate, high in environmental adaptability and high in application value.