The present invention provides a PBT permanent antistatic material and a preparation method and application thereof, and the PBT antistatic material is prepared from 5-25% of flame-retardant electrostatic-conductive dissipative masterbatch and 75-95% of PBT. In the method, the flame-retardant electrostatic-conductive dissipative masterbatch and the PBT are blended and extruded to obtain the PBT antistatic material, the PBT antistatic material reaches high oxygen index flame retardant V0 level, the volume resistivity is 10<6-8> Omega, the surface resistivity is 10<6-9> Omega, and the electrostatic decay time is greater than 10s, so that breakdown and serious harm due to static electricity of products in the various fields can be solved, and the PBT permanent antistatic material is non-dependence on temperature and humidity, is widely used in intelligent micro-electronics, electrical appliances, electrostatic sheet packaging, wires and cables, optical photovoltaic solar energy, machinery, medical equipment, electrostatic textiles of clothing and shoes, fire protection, military electrostatic equipment, electrostatic explosion-proof industry, gas electrostatic protection safety, firework electrostatic protection safety, petroleum and chemical energy and gas station electrostatic protection, and other fields.