The present invention describes a pixel driving circuit, a driving method, and an organic light-emitting display panel. The pixel driving circuit comprises a first transistor, a second transistor, a third transistor, a fourth transistor, a fifth transistor, a sixth transistor, a seventh transistor, an eighth transistor and a capacitor. A first node is arranged between the fourth transistor and the fifth transistor. The seventh transistor is coupled in series between a reference voltage line and the first node. The eighth transistor is coupled in series between the reference voltage line and the anode of a light-emitting element. According to the invention, the pixel driving circuit solves the display unevenness problem caused by the reasons of threshold voltage drift, device degradation and the like in the prior art. Meanwhile, the grid potential stability of a driving transistor, under the influence of a leakage current generated due to the fact that the voltage difference between the two ends of a switching transistor is relatively large in the prior art, can be improved at the same time.