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System for detecting protease

InactiveUS7109293B2Suppress viral proliferationDecreased crop yieldCompound screeningApoptosis detectionProteinase activityProtease
Disclosed is a system for detecting a protease inside a cell. In one embodiment, the system includes a chimeric protein that comprises as covalently linked components: 1) at least one optionally masked signal protein; 2) at least one protease-specific cleavage site; and 3) at least one detectable amino acid sequence. The invention has a wide spectrum of applications including use in the detection of novel protease inhibitors inside cells and tissue.
Owner:AHRAM BIOSYST

Apparatus and method for measuring a temperature of coolant in a reactor core, and apparatus for monitoring a reactor core

A reactor core coolant temperature measuring apparatus for measuring the temperature of the coolant flowing in the reactor core of a nuclear reactor comprises a γ-ray thermometer having a temperature measuring section arranged below the bottom of the reactor core and a γ-ray heat generation detecting section arranged between the bottom and the top of the reactor core, a cable for transmitting the signal output from the temperature measuring section and an output signal processing means for receiving the signal and computationally determining the local temperature of the coolant at the position of placement of the temperature measuring section.
Owner:KK TOSHIBA

Medical device for removing a vascular occlusion

Device for removing a complete vascular occlusion using a CTO catheter, at the distal end of which are disposed stretching tongs and IVUS monitoring, whereby the CTO catheter is combined with an IVUS catheter to form an integrated unit.
Owner:SIEMENS HEALTHCARE GMBH

Digital multi-point temperature measuring system and achieving method

The invention relates to a digital multi-point temperature measuring system and an achieving method. A power module is respectively connected with a digital temperature sensor, a computing control module, a communication module, an alarming module and a display module, the digital temperature sensor is respectively connected with the communication module, the alarming module and the display module through the computing control module, and the communication module is connected with a computer; after an ID number, an alarming line, an alarming return difference and an alarming method of an instrument are set and the sensor is logged in, the instrument can work. Data of the sensor are converted into temperature numerical value through a single-chip microcomputer and compared with the set alarming line, the temperature value is transmitted to the display module to be displayed by the single-chip microcomputer, if alarming is needed, the single-chip microcomputer controls the alarming module to give out an alarm, and if communication is needed, the single-chip microcomputer controls the communication module to be in communication with the computer. Thus, stability of signals in the transmission process is improved, the size of the instrument is reduced, requirements for a power source are lowered, mutual effects between circuits are reduced, and temperature information can be observed remotely.
Owner:ZHONGHUAN TIG

Processing method and device for polarization-maintaining optical fiber pigtail in non-melting point optical fiber gyroscope

The invention relates to a method and device for processing polarization-maintaining optical fiber pigtails in a non-melting point optical fiber gyroscope. The processing method includes preparing an array of optical fiber fixed blocks, a fixed axis of polarization-maintaining optical fiber pigtails, a polarization-maintaining optical fiber ring tail fiber together with an array of fixed blocks and an array of accompanying blocks. Grinding and polishing together and dividing the optical fiber fixed block array after polishing. The invention also provides an improved axis-fixing device for polarization-maintaining optical fiber pigtails. The end face processing is carried out on the same array fixed block together, instead of the traditional method of fixing the axis of a single optical fiber fixed block, which greatly improves the processing efficiency, makes the product consistent, and the process is simple. The card reduces the difficulty of card installation, and the end-face structure of the polarization-maintaining fiber can be clearly observed by setting an external light source and collecting images by a computer, which improves the axis positioning accuracy.
Owner:BEIJING AEROSPACE TIMES OPTICAL ELECTRONICS TECH

Remote confined-space machining, and positioning and securing arrangement

A machining tool comprises a frame mounting an extendable yoke slidable with respect to the frame in a first direction through one or more mounting pillars. A tool motor is mounted on the yoke. A drive mechanism for the yoke is also mounted in the frame, with a drive motor to drive the yoke drive mechanism. A belt is between pulleys on the drive motor and mechanism to transmit drive between them. A rotatable sleeve is around the tool motor and on which sleeve the belt engages on opposite sides of the tool motor, whereby the tool motor can extend between the drive motor and mechanism, thereby resulting in a compact arrangement of the tool.
Owner:UNIV OF SHEFFIELD

Screening method of febrile convulsion model rat and application thereof

The invention relates to the technical field of establishment of an animal model used for screening drug and researching disease mechanism, in particular to a screening method of a febrile convulsion model rat, which can be used for obtaining the model rat by screening in a way of combining a typical water bath heating induction model with artificial directional selection and mating breeding. Themethod is unique and can be used for successfully obtaining the good febrile convulsion sensitive model rat and a tolerance model rat.
Owner:WUHAN UNIV

Cell suspension medium and cell suspension medium additive for the three dimensional growth of cells

The present invention relates to a cell culture medium additive comprising a xanthan polysaccharide and a mannan polysaccharide, such as a glucomannan or a galactomannan, that supports the growth of cells in suspension, and to a cell culture medium containing the additive. More particularly, but not exclusively, the present invention relates to a cell culture medium additive that supports the formation of multicellular bodies such as spheroids, and prevents sedimentation of cells without adversely affecting the physical properties of the cell culture medium.
Owner:TRINITY COLLEGE DUBLIN

Pollution halo layered observation device and method for simulating pollutant contaminated soil

The invention relates to a pollution halo layered observation device and method for simulating pollutant contaminated soil. The device comprises a soil sample box and a feeding device for feeding pollutants, wherein the feeding device is positioned above a feeding box; the soil sample box is formed by splicing multiple soil layer cavities (1) which are laminated vertically; and a calibrated scale (5) is arranged on a side plate of the soil layer cavities (1). The observation method comprises the following steps of: 1, borrowing soil; 2, feeding pollutants into the soil sample box through the feeding device; 3, separating the soil sample box into independent soil layer cavities; 4, projecting a pollutant range on the soil surface layer in each soil layer cavity to a two-dimensional coordinate system by using the calibrated scale; and 5, projecting a two-dimensional projection drawing on the soil surface layer in each soil layer cavity into a three-dimensional coordinate system according to the height position of the soil surface layer in each soil layer cavity, and connecting to form a three-dimensional pollution halo. According to the observation device and method, the pollution halo can be conveniently, directly and accurately observed on the basis that the influence to the soil structure is minimum.
Owner:CHINA UNIV OF GEOSCIENCES (WUHAN)

Method and device for indicating scanning condition and scanning apparatus and scanning system related thereto

A method and device for indicating a scanning condition and a scanning apparatus and scanning system related thereto are provided. The method includes: converting a scanning condition of a scanning apparatus into a control instruction for controlling a light strip to provide an indication; and executing the control instruction to control the light strip to provide the indication in the case of the scanning condition, wherein the light strip is mounted on an exterior of the scanning apparatus. Thus, the scanning condition of a scanning apparatus is converted into a control instruction for controlling the light strip to provide the indication, and the control instruction can be executed to control the light strip on the exterior of the scanning apparatus to indicate the scanning process when the scanning condition of the medical-scanning apparatus occurs.
Owner:SHENYANG NEUSOFT MEDICAL SYST CO LTD

Tungsten filament rope coiling machine charge coupled device (CCD) image capture display method and detecting device thereof

The inventions aims to provide a tungsten filament rope coiling machine charge coupled device (CCD) image capture display method and a detecting device thereof so as to solve the problem of monitoring in a tungsten filament rope coiling process. The tungsten filament rope coiling machine CCD image capture display method is characterized in that image formation of a tungsten filament rope is carried out in a twisting process, images of the tungsten filament rope are magnified by a precision microscope, projected on a CCD chip and processed into electric information which is transmitted to a display processing system through a CCD, and the images of the tungsten filament rope are enlarged and displayed in a display surface. The detecting device which achieves the tungsten filament rope coiling machine CCD image capture display method is characterized in that a CCD image capture display detection device body is fixedly connected with a special base arranged on a tungsten filament rope coiling machine through a microscope base, the upper portion of the microscope base is provided with a light source which directly shines on the tungsten filament rope, the CCD is arranged on the upper portion of the microscope, the CCD chip is connected with a display. The tungsten filament rope coiling machine CCD image capture display method and the detecting device thereof have the advantages that silk, strands and ropes are quite thin and are enlarged, so that observation and monitoring are convenient, direct and clear; the display method and the detecting device are beneficial for finding out defects of tungsten filament, tungsten filament strands and tungsten filament ropes in a production process, and enhance guaranteeing of quality of tungsten filament rope products and improvement of monitoring level.
Owner:符云舒
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