109results about How to "Reduced elution" patented technology

A resist composition for immersion exposure, including a base component (A) that exhibits changed solubility in an alkali developing solution under action of acid, an acid generator component (B) that generates acid upon exposure, and a fluorine-containing compound (C) represented by a general formula (c-1) shown below that is decomposable in an alkali developing solution:wherein R1 represents an organic group which may contain a polymerizable group, with the proviso that said polymerizable group has a carbon-carbon multiple bond, and the carbon atoms forming the multiple bond are not directly bonded to the carbon atom within the —C(═O)— group in general formula (c-1); and R2 represents an organic group having a fluorine atom.

A positive resist composition including a base component, an acid-generator component and a fluorine-containing polymer component (F) in a specific amount, the fluorine-containing polymer component (F) including a fluorine-containing polymer (F1) consisting of a structural unit (F-1) represented by general formula (F-1) (RC represents a hydrogen atom or a methyl group, R1 and R2 represent a hydrogen atom, an alkyl group or a fluorinated alkyl group, R3 represents a fluorine atom or a fluorinated alkyl group, and R4 represents an alkyl group or a fluorinated alkyl group) or a fluorine-containing copolymer (F2) containing the structural unit (F-1) and at least one structural unit selected from the group consisting of a structural unit (F-2) derived from an acrylate ester containing an acid dissociable, dissolution inhibiting group and a structural unit (F-3) represented by general formula (F-3) (RC represents a hydrogen atom or a methyl group, Z represents a single bond or a divalent linking group, and r represents an integer of 0 to 2).

Implantable medical devices may be utilized to locally delivery one or more drugs or therapeutic agents to treat a wide variety of conditions, including the treatment of the biological organism's reaction to the introduction of the implantable medical device. These therapeutic agents may be released under controlled and directional conditions from a stent so that the one or more therapeutic agents reach the correct target area, for example, the surrounding tissue.

A positive resist composition including a polymeric compound (A1) having a structural unit (a0) represented by general formula (a0-1) (R represents a hydrogen atom, an alkyl group of 1 to 5 carbon atoms or a halogenated alkyl group of 1 to 5 carbon atoms, R2 represents a divalent linking group, R3 represents a cyclic group containing —SO2— within the ring skeleton thereof) and a structural unit (a1) derived from an acrylate ester containing an acid dissociable, dissolution inhibiting group, an acid-generator component (B) and a fluorine-containing polymeric compound (F1) having a structural unit containing a base dissociable group.

A fluorine-containing polymeric compound which contains a structural unit (f1) that is decomposable in an alkali developing solution as a block copolymer portion, a base component (A) that exhibits increased solubility in an alkali developing solution under the action of acid, and an acid generator component (B) that generates acid upon exposure.

The invention discloses arsenic removal material by adsorption of electrochemistry strengthened carbon fiber loaded nano ferro-manganese and an arsenic removal method by using the material. The material comprises a substrate material and nano ferro-manganese oxidesloaded on the substrate material through electrochemistry and electro-deposition; the substrate material can be carbon fiber yarns, carbon fiber felts or graphite carbon fiber felts, and the shape of the substrate material is cylindrical or flat-shaped; and when a three-dimensional electrode is used, the substrate material is activecarbon. The arsenic removal material is prepared by performing ferro-manganese metal salt surface electro-deposition on the substrate material by electrifying. The arsenic removal method comprises the following steps of: carrying out coupling electro-absorption in the process of arsenic removal by chemical absorption, and strengthening the arsenic removal effect by using the electro-absorption action of a charging capacitor in the absorption process; applying reverse current to facilitate arsenic desorption on a surface of ferro-manganese hydrated oxide in a regeneration process, and simultaneously applying high voltage to perform hydrolysis, hydrogen generation and oxygen evolution so as to facilitate activity regeneration of the ferro-manganese oxide. With the adoption of the material and the method, the high absorption effect and the quick regeneration capability can be achieved.

A resist composition for immersion exposure, including a base component (A) that exhibits changed solubility in an alkali developing solution under action of acid, an acid generator component (B) that generates acid upon exposure, and a fluorine-containing compound (C) represented by general formula (c-1) (in formula (c-1), R1 represents an organic group which may contain a polymerizable group; X represents a divalent organic group having an acid dissociable portion; and R2 represents an organic group having a fluorine atom).

A Coriolis flowmeter includes an oscillator for oscillating a fluid pipe that forms a flow path for allowing a measurement fluid to flow; first and second detectors that are disposed to be spaced apart from each other along the flow path of the fluid pipe so as to detect a state of oscillation of the fluid pipe; and a calculator for calculating a mass flow rate of the measurement fluid that passes through the flow path of the fluid pipe on the basis of a relative amount of the states of oscillation that are detected by the first and second detectors. The fluid pipe includes an inner pipe made of a fluororesin whose inner circumferential surface is in contact with the flow path, and an outer pipe having fibers that are arranged in order to surround an outer circumferential surface of the inner pipe and a resin that is cured in a state of close adhesion between the fibers arranged in order, and having an elastic modulus larger than that of the inner pipe.

A dialyzer for blood treatment including a semipermeable membrane which is made of a hydrophobic polymer and a hydrophilic polymer, and has a water permeating performance drying of ½ or higher relative to that before drying. The dialyzer has a vitamin B12 clearance not smaller than 135 ml / mm per 1.6 m2 or the amount of the hydrophilic polymer eluted from the semipermeable membrane is not higher than 10 ppm. A dialyzer for blood treatment is light-weight, easy to handle, and exhibits a reduced elution of the hydrophilic polymer procedures for producing a dialyzer containing the semipermeable membrane and a process for producing a hollow fiber membrane for use in blood treatment are described.

A dialyzer for blood treatment including a semipermeable membrane which is made of a hydrophobic polymer and a hydrophilic polymer, and has a water permeating performance drying of ½ or higher relative to that before drying. The dialyzer has a vitamin B12 clearance not smaller than 135 ml / min per 1.6 m2 or the amount of the hydrophilic polymer eluted from the semipermeable membrane is not higher than 10 ppm. A dialyzer for blood treatment is light-weight, easy to handle, and exhibits a reduced elution of the hydrophilic polymer procedures for producing a dialyzer containing the semipermeable membrane and a process for producing a hollow fiber membrane for use in blood treatment are described.

It is intended to provide a blood purification membrane having excellent performance and showing little elution of blood and little adhesion of blood proteins or platelets. The above object can be achieved by using a moisten membrane, which is free from any membrane pore-sustaining agent and has a high water permeation dose and a large pore size, and lessening the pore size by drying the membrane after desolvation.

A resist composition for immersion exposure including: a fluorine-containing polymeric compound (F) containing a structural unit (f1) having a base dissociable group and a structural unit (f2) represented by general formula (f2-1) (wherein R represents a hydrogen atom, a lower alkyl group or a halogenated lower alkyl group; and W is a group represented by any one of general formulas (w-1) to (w-4)); a base component (A) that exhibits changed solubility in an alkali developing solution under the action of acid; and an acid generator component (B) that generates acid upon exposure.

A resist composition for immersion exposure including: a base component (A) which exhibits changed solubility in an alkali developing solution under the action of acid; an acid-generator component (B) which generates acid upon exposure; and a fluorine-containing resin component (F); dissolved in an organic solvent (S), the fluorine-containing resin component (F) including a structural unit (f1) containing a fluorine atom, a structural unit (f2) containing a hydrophilic group-containing aliphatic hydrocarbon group, and a structural unit (f3) derived from an acrylate ester containing a tertiary alkyl group-containing group or an alkoxyalkyl group.

A multi-layered medical container formed by a multi-layered film, in which an innermost layer is a layer comprising a cyclic polyolefin or a polymer blend containing the cyclic polyolefin, and a layer, which is adhered to the above-described layer, having a linear polyolefin or polyamide is provided. Also, a multi-layered medical plural chamber container which includes a body divided by a peelable seal portion into a medical liquid-containing chamber that stores the medical liquid and a medicament-containing chamber that stores the medicament is provided.

Provided is a composition for hot melt extrusion including a drug and hypromellose acetate succinate (HPMCAS) having a hydroxypropoxy molar substitution of 0.40 or more and a mole ratio of an acetyl group to a succinyl group of less than 1.6. Further, provided is a method for producing a hot melt extrudate including the step of hot melt-extruding a composition for hot melt extrusion including a drug and hypromellose acetate succinate having a molar hydroxypropoxy substitution of 0.40 or more and a mole ratio of an acetyl group to a succinyl group of less than 1.6, at a hot melt temperature of not lower than a melting temperature of the hypromellose acetate succinate or of not lower than a temperature at which both the hypromellose acetate succinate and the drug are melted.

Provided is a method for plating a biocompatible coating with nano structure on the surface of a nickel-titanium shape memory alloy, particularly a method suitable for plating a coating on the surface of medical devices made of nickel-titanium alloy. The method includes the following steps: heat treating, surface pretreating, ion sputter cleaning, depositing a pseudodiffusion layer, plating a sub-layer film, plating a pure TiN layer, and so on. The coating has the following advantages: 1) it could deform in response to the deformation of substrate without delaminating and cracking; 2) it has less resistance to the deformation of substrate; 3) it has less penetrable holes so as to reduce the dissolution of nickel into bio-body through these holes; 4) the coating has better biocompatibility compared to the substrate material.

The invention discloses a method for preparing total ginkgo flavone glycosides slow-release capsules by applying attapulgite, which comprises the following steps of: washing, drying and pulverizing gingko leaves into coarse powder; adding the gingko leaf coarse powder and petroleum ether with the weight ten times of the gingko leaf coarse powder into a container, refluxing and extracting for 1 hour, degreasing, filtering and drying; adding water with the weight ten times of the degreased gingko leaf coarse powder into the degreased gingko leaf coarse powder, boiling, decocting for 3 times, combining decocting liquids, filtering and concentrating to the relative density of 1.10; adding ethanol with the mass concentration of 95 percent into a concentrated liquid until the ethanol concentration is 70 percent, depositing, settling and filtering; adsorbing a filtrate through modified attapulgite to obtain the attapulgite loading total ginkgo flavone glycosides; and adding a pharmaceutical adjuvant material into the attapulgite loading total ginkgo flavone glycosides, and encapsulating into empty capsules to obtain the total ginkgo flavone glycosides slow-release capsules. The invention adopts the principle of adsorption separation and selects the modified attapulgite with strong adsorbability for the total ginkgo flavone glycosides to directly prepare a preparation without elution, the total ginkgo flavone glycosides slow-release capsules are slowly desorbed under the desorption action of a body fluid, steps are simplified, the production period is shortened, and the yield of products is improved.

An inkjet recording method includes a step of forming an image by imparting an actinic ray curable ink composition containing a pigment, a polyfunctional polymerizable compound in which a content ratio to a total polymerization component is 80% by mass or more and a sensitizer in which a molecular weight is 1,000 or more onto a recording substrate which is an aggregate of a nonabsorbable or a low absorbable fiber material from an inkjet head under the conditions in which an amount of ink droplets is from 25 pl to 200 pl and a distance between the recording substrate and the inkjet head is from 5 mm to 20 mm, and a step of curing the image by irradiating the formed image with an actinic ray under the conditions in which an oxygen partial pressure is 1.5×10−2 MPa or less.

[Purpose] To provide a blood purifier which has high levels of blood compatibility, performance-retaining property when in contact with blood, and safety, and which shows an excellent water permeability-exhibiting rate after a priming treatment and has high reliability in long-term storage.[Solution] A blood purifier assembled using a polyvinyl pyrrolidone-containing polysulfone-based permselective hollow fiber membrane bundle, characterized in thatthe amount of polyvinyl pyrrolidone which elutes from the hollow fiber membrane bundle is 10 ppm or less,the amounts of hydrogen peroxide which elute from extracts from all the sites of the hollow fiber membrane bundle are 5 ppm or less, when the hollow fiber membrane bundle is divided into 10 portions in the lengthwise direction to test the sites of all the 10 portions according to the method regulated in the Approval Standard for Dialysis-Type Artificial Kidney Apparatus, andthe water permeability of the blood purifier found at a point of time when 10 minutes has passed since the priming treatment of the blood purifier is 90% or more of the water permeability of the same found at a point of time when 24 hours has passed since the priming treatment thereof.

A modified atomic plasma deposition (APD) procedure is used to produce amorphous, nonconformal thin metal film coatings on a variety of substrates. The films are porous, mesh-like lattices with imperfections such as pinholes and pores, which are useful as scaffolds for cell attachment, controlled release of bioactive agents and protective coatings.

Adhesive composition and a flexible packaging composite film that can produce a reduced amount of low-molecular-weight compounds eluted into contents of a composite film to prevent spoilage of inherent properties or performances of the contents, can produce improved oil resistance to prevent significant reduction in strength even when used for oily contents, and can develop favorable flexibility of the composite film to prevent reduction in peel strength. Polyester polyamide polyol and / or polyurethane polyester polyamide polyol including an amide bond produced by reaction between a dimer acid and polyamine is prepared as a polyol component and also concentration of a cyclic compound formed by the amide bond and / or an ester bond in extracted water which is extracted from a composite film adhesively bonded by the adhesive composition by water of 0.5 mL / cm2 per unit area of the composite film is set to be 0.5 ppb or less in terms of dibutyl phthalate concentration measured with a gas chromatograph-flame ionization detector.

To provide a solid electrolytic capacitor where solid electrolyte is formed at the cut end part and at the masking part to a larger thickness than in other parts, where the adhesion of the solid electrolyte formed on the valve acting metal oxide film is improved, and whereby the capacitor is highly stabilized in various basic properties such as capacitance, dielectric loss (tan δ), leakage current and short circuit defective ratio and also in the reflow soldering heat resistance and moisture resistance load characteristics.These solid electrolytic capacitor can be obtained by forming electrically conducting polymer on a dielectric film by specifying time for dipping of the surface of a valve actiong metal porous body with a solution containing a monomer and with a solution containing an oxidizing agent, time for vaporization of the solvent of the solution containing a monomer, and polymerization conditions after dipping of the solution containing an oxidizing agent.

A positive resist composition including a resin component (A) which exhibits increased solubility in an alkali developing solution under the action of acid and an acid-generator component (B), the resin component (A) including a polymeric compound (A1) having a structural unit (a1) containing an acid dissociable, dissolution inhibiting group, a structural unit (a5) containing a base dissociable group an a structural unit (a6) represented by general formula (a6-1) (R represents a hydrogen atom, an alkyl group of 1 to 5 carbon atoms or a halogenated alkyl group of 1 to 5 carbon atoms; each of R2 and R3 independently represents a hydrogen atom or an alkyl group that may contain an oxygen atom at an arbitrary position, or R2 and R3 are bonded together to form an alkylene group; and W represents a cyclic alkylene group that may include an oxygen atom at an arbitrary position).

A laminate adhesive that can suppress elution of a low molecular weight compounds of a composite film into the content, so as to prevent the inherent properties or performances of the content from being spoiled by the low molecular weight compounds. In the laminate adhesive, the polyester polyol contains naphthalenedicarboxylic acid and / or alkyl ester thereof as an acid component, and concentration of cyclic ester compounds in extracted water, which are extracted from a composite film bonded by the laminate adhesive by water of 0.5 mL / cm2 per unit area of the composite film, is 0.5 ppb or less in terms of dibutyl phthalate concentration measured by a gas chromatograph-flame ionization detector.