89results about How to "Use optimization" patented technology

The invention provides an automatic injection device for providing a subcutaneous injection of a substance into a user, comprising: a housing having an open first end and a second end; a syringe movably disposed in the housing, the syringe including a barrel portion for holding the substance, a hollow needle in fluid communication with the barrel portion for ejecting the substance from the syringe, and a bung for sealing the barrel portion and selectively applying pressure to the substance to force the substance through the hollow needle; a plunger for first moving the syringe towards the first end such that the needle projects from the first end and subsequently applying pressure to the bung, the plunger including a rod connected at a first end to the bung, a compressible expanded central portion and a flange between a second end of the rod and the compressible expanded central portion; and a biasing mechanism for biasing the plunger towards the first open end of the housing, the biasing mechanism disposed about the second end of the rod between the flange and the second end of the housing. The present invention also provides methods and kits for using an automatic injection device, and methods and kits for promoting an automatic injection device comprising a medication based on advantageous properties of the device as compared to a pre-filled syringe. The invention also provides methods and kits for training a recipient on use of the automatic injection device.

Novel indole and azaindole compounds of the following structure and their use as fructose-1,6-bisphosphatase inhibitors is described: and pharmaceutically acceptable prodrugs and salts thereof.

Novel benzimidazole compounds of the following structure and their use as fructose-1,6-bisphosphatase inhibitors is described

Novel purine compounds of the following structure and their use as fructose-1,6-bisphosphatase inhibitors is described.whereinA is selected from the group consisting of -NR82, -NHSO2R3, -OR5, -SR5, halo, lower alkyl, -CON(R4)2, guanidino, amidino, -H, and perhaloalkyl;E is selected from the group consisting of -H, halo, lower alkylthio, lower perhaloalkyl, lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, -CN, and -NR72;X is selected from the group consisting of -alk-NR-, alkylene, alkenylene, alkynylene, arylene, heteroarylene, -alk-NR-alk-, -alk-O-alk-, -alk-S-alk-, -alk-S-, alicyclicene, heteroalicyclicene, 1,1-dihaloalkylene, -C(O)-alk-, -NR-C(O)-NR'-, -alk-NR-C(O)-, -alk-C(O)-NR-, -Ar-alk-, and -alk-Ar-, all optionally substituted, wherein each R and R' is independently selected from -H and lower alkyl, and wherein each "alk" and "Ar" is an independently selected alkylene or arylene, respectively;Y is selected from the group consisting of -H, alkyl, alkenyl, alkynyl, aryl, alicyclic, heteroalicyclic, aralkyl, aryloxyalkyl, alkoxyalkyl, -C(O)R3, -S(O)2R3, -C(O)-OR3, -CONHR3, -NR22, and -OR3, all except H are optionally substituted; andpharmaceutically acceptable prodrugs and salts thereof.

The invention relates to a permanent magnet synchronous motor low inverter power consumption direct torque control method and device. The permanent magnet synchronous motor low inverter power consumption direct torque control method adopts predictive control strategies. Compared with the space-vector-modulation-based direct torque control and the common direct torque control, the permanent magnet synchronous motor low inverter power consumption direct torque control method has the advantages of enabling the integral inverter switching frequency to be the lowest, optimally using a power device and reducing the switching loss of the inverter due to the facts that predicted values of the torque and the stator flux linkage are predicated according to an interior model of a controller based on the given reference values of the torque and the stator flux linkage and a most suitable switching position for the inverter is obtained through a minimization objective function which comprises the flux linkage, the torque and the average switching frequency within the forecast time domain and enabling online computing time to be greatly reduced due to the fact that the control law is fed back through an offline computing state, maintaining good dynamic performance and robustness of the common direct torque control and maintaining the flux and the torque to be within a corresponding hysteresis range.

The invention relates to a traffic signal optimization control method for the vehicle queuing overflow state at road intersections, and overcomes the defect that an image monitoring and control signal lamp cannot apply to queuing overflow optimization control compared with the prior art. The method of the invention comprises the following steps: traffic flow parameters of a road intersection are acquired; the queuing length is calculated; the queuing overflow state at the road intersection is judged; and the green light time of an upstream intersection is calculated. The queuing length parameters and queuing overflow events are detected in real time by vehicle detectors installed at the entrances and the exits of road intersections, and balancing of the queuing lengths of all intersections in a region is realized by adjusting the green light time of traffic signal control, thus solving the problem of queuing overflow at intersections.

A stem cell which is obtainable from the non-embryonic tissue isolated from the dental follicle of tooth or wisdom tooth which are able to differentiate into a periodontal ligament like membrane structure.

A process is disclosed for producing with good productivity a cross-linked polyaspartic acid resin having biodegradability and high water absorbency. The process features inclusion of one of the following steps: (a) a polysuccinimide, which has been brought into a dispersed state by a dispersant, and a cross-linking agent are reacted to produce the cross-linked polyaspartic acid resin; (b) imide rings of a cross-linked polysuccinimide are subjected to a hydrolysis reaction while controlling a swelling degree of a resulting gel, whereby the cross-linked polyaspartic acid resin is produced; and (c) a gel of a cross-linked polysuccinimide, which has been obtained by reacting a cross-linking agent to a solution of a polysuccinimide in an organic solvent, is disintegrated to subject imide rings of the cross-linked polysuccinimide to a hydrolysis reaction, so that the cross-linked polyaspartic acid resin is produced. The process may also include one or both of the following steps as needed: (d) a gel of the cross-linked polyaspartic acid resin is washed with water and / or a water-miscible organic solvent; and (e) the polysuccinimide is produced using a basic amino acid as a cross-linking agent.

A process for the for the preparation of dynamically vulcanized thermoplastic elastomers is described. The process comprises melt processing under high shear conditions A) at least one thermoplastic engineering resin, B) at least one vulcanizable rubber, C) a curing agent or curing agents, and D) at least one additional thermoplastic engineering resin in the form of solid particles having an effective diameter of not less than 0.05 mm, wherein said solid particles D) are added to a molten mass of A), B) before, during or after the addition of C) but prior to substantial completion of the vulcanization of B). The process provides a means to avoid substantial degradation or unwanted cross-linking of the thermoplastic engineering resin and provides a means of controlling the reaction temperature during the curing, vulcanization, or cross-linking of the rubber.

An object of this invention is to provide a sleep improvement composition, which contains theanine and other components and can be used safely by anybody on a daily basis without side effects. This object is attained by a sleep improvement composition comprising: (a) theanine; and (b) at least one component selected from the group consisting of chamomile, lavender, Saint John's wort, kawakawa, valerian, passion flower, tryptophan, γ-aminobutyric acid, serotonin, melatonin, and cedrol.

A lithium secondary battery, including a positive electrode, a negative electrode, a separator, an internal electrode body, and an organic electrolyte, the positive electrode and the negative electrode being wound through the separator so that the positive electrode and the negative electrode are not brought into direct contact with each other, wherein when the number of turns of the positive electrode or the negative electrode per unit length (turns / cm) along the direction of diameter of the internal electrode body is multiplied by total thickness (cm) of the electrode active material layers, being designated as a correction winding density (turns), the correction winding density is not less than 0.73 (turns).

Disclosed are novel metal pterin and pterin analog complexes and compositions useful as antineoplastic and antiviral agents.

A method is provided for analyzing nucleic acid comprising the steps of extracting, amplifying and detecting the nucleic acid of interest, wherein one or more internal control nucleic acids which can be detected and discriminated from the nucleic acid of interest are added for each step to a sample prior to the performance of each step, and the success or failure of each step is judged from the detection results obtained for the respective internal control nucleic acids in the detection step. The internal control nucleic acids added prior to each step can be discriminated from each other.

Objects of the present invention are to provide a blood purifier package which shows a less increase in the amounts of extracts from the materials of its blood purifier, particularly of its selective permeable separation membranes, attributed to the deterioration of the same materials with time after exposure to a radioactive ray or an electron ray, and which is therefore highly reliable in safety in use for hemocatharsis, and to provide a process for manufacturing the same. The present invention relates to a blood purifier package obtained by packing a blood purifier which comprises selectively permeable separation membranes as a main component, and this blood purifier package is characterized in that the blood purifier is packed and sealed together with an oxygen scavenger in a packaging material capable of shutting out an external air and a water vapor, under a condition of a relative humidity of above 40% RH at 25° C.

The invention relates to a clustering routing method based on a wireless sensor network node middleware. The clustering routing method is characterized in that an improved LEACH (low energy adaptive clustering hierarchy) routing protocol based on energy saving and relay decreasing is proposed on the foundation of existing LEACH protocol to effectively reduce energy consumption during LEACH cluster forming procedure; dynamic adaptive power control is adopted for controlling power of data transmitting phase; after nodes in clusters are added into corresponding clusters, respective channels are switched to the channels assigned by cluster heads; back-off and latency time of adjacent nodes are reduced to an extreme. The improved LEACH routing protocol is allocated in a network protocol stack of the sensor network middleware, adopts a service primitive manner, acquires physical link resource through 'Request' primitive from the data link layer below, and determines more proper routing protocol strategy according to returned 'Response' messages from the data link layer. By the aid of the clustering routing method, two phases of cluster head selection and adaptive transmission are respectively improved.

The present invention aims to provide a wearing article improved so that various types of nonwoven fabrics can be effectively used for target nonwoven fabric without anxiety that the target nonwoven fabric once engaged with hook elements might be readily torn. As an outer sheet 8 defining a garment-facing side of a chassis 2, a commonly-used nonwoven fabric is used and this nonwoven fabric is oriented in a longitudinal direction Y. Rear waist region's side edges 14 of the chassis 2 are provided with flaps 16 attached thereto. Each of the flaps 16 has a joint region 19 along which the flap 16 is joined to the chassis 2 and first and second hook elements 21, 22. Between the joint region 19 and the first and second hook elements 21, 22 as viewed in the transverse direction X, a contractible region 23 adapted to be contractible in the transverse direction X. The contractible region 23 is provided with a plurality of flap's elastic members 24. The joint region 19 provided with none of the flap's elastic members 24 define a non-contractible region. The first and second hook elements 21, 22 of the flap 16 may be put in engagement with the outer sheet 8 to connect the front and rear waist regions 4, 5 to each other in a circumferential direction.

The present invention relates to a key remote controller (2) used for unlocking / locking and / or starting / parking, comprising a code apparatus connected with control devices (16-18, 20) and a coil arrangement (4) connected with the control devices, wherein the coil arrangement is used for wirelessly communicating with an antenna coil mechanism (10-12) of the motor car-side control device (1), the coil arrangement (4) comprises three or more coils that are oriented in three directions of space, the coils are coupled with the control devices (16-18, 20) such that the control devices can determine which coil receives a first signal in the largest intensity when the coil arrangement (4) receives the first signal emitted by the motor car-side antenna coil arrangement (10-12), and then a second signal transmitted from the key remote controller (2) to the motor car-side control devices (1) is emitted by the coil or one of the coils receiving the first signal in the largest field intensity through the control devices.

Disclosed is a compound having excellent electron transporting ability, which is useful for electrophotographic photosensitive bodies or organic EL devices. Specifically disclosed is a novel quinone compound having a structure represented by general formula (I). Also disclosed is a highly sensitive, positive charge type electrophotographic photosensitive body for copying machines and printers, wherein the novel organic material is used as a charge-transporting material in a photosensitive layer. Also specifically disclosed is an electrophotographic photosensitive body having a photosensitive layer formed on a conductive base and containing a charge-generating material and a charge-transporting material, wherein the photosensitive layer contains at least one of the above-described compounds. Further disclosed is an electrophotographic apparatus using such a positive charge type electrophotographic photosensitive body.

The invention is an interrupt-based real-time task controlling method, able to ensure higher real-timeness and stability on the premise of not adding the extra resources overhead of the system, bringing a task as a virtual interrupt into an interrupt system for controlling, and adopting a table look-up mode to obtain the highest propriety interrupt and virtual interrupt, where the controlling time is constant and does not change with the number of the interrupts and virtual interrupts. It has a simple principle and easy to implement, and particularly applied to medium and low -side embedded real-time systems.

A process for the for the preparation of dynamically vulcanized thermoplastic elastomers is described. The process comprises melt processing under high shear conditions A) at least one thermoplastic engineering resin, B) at least one vulcanizable rubber, C) a curing agent or curing agents, and D) at least one additional thermoplastic engineering resin in the form of solid particles having an effective diameter of not less than 0.05 mm, wherein said solid particles D) are added to a molten mass of A), B) before, during or after the addition of C) but prior to substantial completion of the vulcanization of B). The process provides a means to avoid substantial degradation or unwanted cross-linking of the thermoplastic engineering resin and provides a means of controlling the reaction temperature during the curing, vulcanization, or cross-linking of the rubber.

There is described a method for selecting a transmission path for a communication connection of a mobile communication device, wherein at least two transmission paths can be selected by the mobile communication device. In a first step, an option is determined via the position of the communication device, in a second step, the option is accessed using the determined option on the data bank for the transmission path, in a third step, a preferred transmission path is determined using at least one entry of the data bank, and in a fourth step, the preferred transmission path is selected and used for the communication connection.

In a method to determine a B0 field map describing the local deviation of a nominal Larmor frequency of a magnetic resonance apparatus, wherein magnetic resonance data are acquired in measurements implemented at two different echo times whose difference forms a dephasing time after an excitation at at least two different dephasing times, and a phase change to be used to determine the B0 field map is determined from a difference of phases measured at different echo times, the phase changes of different dephasing times are evaluated to at least partially reduce an ambiguity due to a Nyquist phase wrapping, by using dephasing times that result as a quotient or, given the use of only two dephasing times, as a product, of a base time and a respective prime number from a group including at least two different prime numbers that are greater than one, and wherein the group is selected depending on a desired dynamic range of the B0 field map and / or a maximum tolerated measurement error for the measurements.

The present invention provides a blood purifier which shows a decreased amount of hydrogen peroxide extracted from its selectively permeable separation membranes, and thus is highly reliable in its safety in use for hemecatharysis. The present invention relates to a blood purifier which comprises selectively permeable separation membranes as a main component and which is characterized in that the amount of hydrogen peroxide which is extracted from the selectively permeable separation membrane removed from the blood purifier after 3 months or longer has passed since the sterilization of the blood purifier by exposure to a radioactive ray and / or an electron ray is not larger than 10 ppm.

The present invention relates to a method for preparing polyolefin that can easily and effectively prepare polyolefin having high molecular weight and various molecular weight distributions, which was difficult to prepare using the existing metallocene catalyst, and polyolefin prepared thereby. The method for preparing polyolefin comprises the step of polymerizing olefin monomers, in the presence of a metallocene supported catalyst wherein a metallocene compound having a specific chemical structure is supported in a carrier, and hydrogen gas.

The invention discloses a cell-oriented network video sharing system based on analog screen projection. A shared management server is built; an available account and a corresponding password are foundfrom a network video application account pool according to from which video content provider the resource applied to be shared comes; a network video application controller on a sharing terminal logsinto a corresponding network video application, and projects a video onto an analog screen projection player on the same sharing terminal based on a DLNA (Digital Living Network Alliance) technology;the analog screen projection player acquires the URL (Uniform Resource Locator) of corresponding resources (video), and transmits the URL to the network video application controller; the network video application controller transmits the URL to a user controller, and the user controller transmits the URL to a playing terminal; and the playing terminal can connect to a video provider based on theURL to play corresponding videos. Through adoption of the cell-oriented network video sharing system, video resource sharing is realized, and the access right of the video resources is transferred toa user.

The present invention relates to a method for preparing polyolefin that can easily and effectively prepare polyolefin having high molecular weight and various molecular weight distributions, which was difficult to prepare using the existing metallocene catalyst, and polyolefin prepared thereby. The method for preparing polyolefin comprises the step of polymerizing olefin monomers, in the presence of a metallocene supported catalyst wherein a metallocene compound having a specific chemical structure is supported in a carrier, and hydrogen gas.