274results about How to "Prevent elution" patented technology

An intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent incorporated therein. The hydrogel polymer can be coated on the fiber elements in a co-axial configuration. The fiber elements may also have a second coating including a protective substance surrounding the hydrogel polymer having a therapeutic agent therein. The matrix of fiber elements can be formed by electrospinning. A process of delivering a therapeutic agent to a target site includes providing an intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent dispersed therein, and advancing the catheter device at a desired treatment site. Once at the desired treatment site, fluid is introduced into the inflation lumen to expand the expandable member from a first profile to a second profile, and the therapeutic agent is released from the hydrogel polymer and delivered to the desired treatment site.

Provided is a method of manufacturing a glass substrate efficiently via prevention of foreign matter adhesion to a glass substrate as to chemical strengthening. Disclosed is a method of manufacturing a glass substrate for a recording medium possessing the step of conducting a chemical strengthening process by which a glass substrate held by a holding jig and the holding jig are immersed in a chemical strengthening solution, and 1st alkali metal ion on a surface of the glass substrate is substituted by 2nd alkali metal ion having a larger ion diameter than that of 1st alkali metal ion contained in the chemical strengthening solution, wherein the holding jig possesses a member of material made of a metal comprising an alkali metal element, or a metal film comprising an alkali metal element to cover a surface of the holding jig from the very beginning of the chemical strengthening process.

A highly reliable, small-sized, and inexpensive ink jet recording head includes an electrical wiring member that is joined with a back surface of a liquid discharge substrate and includes a liquid supply port communicating with a liquid supply port of the liquid discharge substrate and an electrical connection portion connected to the electrode; and a holding member that holds the liquid discharge substrate through the electrical wiring member and includes a liquid supply port for supplying the liquid to the liquid supply port of the liquid discharge substrate. The liquid supply ports of the electrical wiring member, the liquid discharge substrate, and the holding member communicate with one another. A sealing agent for sealing the electrical connection portion is filled up between the liquid discharge substrate and the electrical wiring member, and a side surface of the liquid supply port of the electrical wiring member is covered with the sealing agent.

A main object of the invention is to provide a manufacturing method of a laminated body which can make the following matters possible: when two or more layers are formed to be laminated by coating, constituents of an underlying layer are restrained from eluting into a solvent in a coating-solution for forming an upper layer; and the plural layers are laminated without restricting the kind of the solvent used in the upper layer forming coating-solution or constituent materials of the upper layer. To resolve the object, the present invention provides a manufacturing method of a laminated body, comprising an underlying layer forming step of coating an underlying layer forming coating-solution comprising a polymer material, thereby forming an underlying layer, and an upper layer forming step of coating an upper layer forming coating-solution on the underlying layer.

A battery with a high battery voltage at charging and improved energy density is provided. A cathode (12) and an anode (14) are laminated with a separator (15) sandwiched therebetween which is impregnated with an electrolyte. The cathode (12) has a cathode active material including a lithium composite oxide which contains lithium, at least either cobalt or nickel, and oxygen. The battery voltage at charging is 4.25 V or more. The total amount of lithium carbonate and lithium sulphate in the cathode (12) to the cathode active material is 1.0 wt % or less, a concentration of protic impurities in the electrolyte, which is converted to a mass ratio of protons to the electrolyte, is 20 ppm or less, or moisture content in the electrolyte is 20 ppm mass ratio or less to the electrolyte. This inhibits metal eluting from the lithium composite oxide even at high voltages.

Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and / or compounds may be utilized to promote healing, including the formation of blood clots. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and / or compounds from the implantable medical devices.

A wax dispersant for a toner including a polymer obtained by graft polymerization of a styrene-acrylic resin onto a hydrocarbon compound, wherein the styrene-acrylic resin has a structural segment derived from a saturated alicyclic compound, and a toner including a toner particle that contains a binder resin, a wax, and a polymer obtained by graft polymerization of a styrene-acrylic resin onto a hydrocarbon compound, wherein the styrene-acrylic resin has a structural segment derived from a saturated alicyclic compound.

A resin to be added to a resist composition and locally distributed on a resist film surface to hydrophobitize the resist film surface includes a residual monomer in an amount of 1 mass % or less to the resin as a whole in terms of solid content.

The invention provides a semiconductor device with a bonding pad made of a wiring layer including aluminum and its manufacturing method that enhance the yield of the semiconductor device. The method of manufacturing the semiconductor device of the invention includes removing a portion of an antireflection layer (e.g. made of a titanium alloy) formed on an uppermost second wiring layer (e.g. made of aluminum) on a semiconductor substrate by etching, forming a passivation layer covering the antireflection layer and a portion of the second wiring layer where the antireflection layer is not formed and having an opening exposing the other portion of the second wiring layer, and dividing the semiconductor substrate into a plurality of semiconductor dice by dicing. These processes can prevent the antireflection layer from being exposed in the opening, and this can prevent a component of the second wiring layer from being eluted due to cell reaction between the second wiring layer and the antireflection layer as has been seen in the conventional art.

An oral care device has a handle with a touch electrode and a brush handle with a brush electrode for flowing a minute current into an oral cavity of a user by way of the user's body for removing plaque. The touch electrode is made of a non-metal material filled with carbon filaments, and is free from any metal elution or corrosion while it is in contact with the user's hand, which assures to keep the oral care device in good appearance and performance over a prolonged use.

Disclosed herein is a method for manufacturing a semiconductor device, the method including the steps of: forming a recess in an insulating film provided over a substrate; forming a plating seed layer in such a way that an inner wall of the recess is covered, the plating seed layer arising from sequential deposition of an alloy layer composed of copper and a metal other than copper and a conductive layer composed mainly of copper; burying a conductive layer composed mainly of copper by plating in the recess on which the plating seed layer is provided; and carrying out heat treatment to cause the metal in the alloy layer to react with a constituent in the insulating film, to thereby form a barrier film composed of a metal compound having a copper diffusion barrier function at an interface between the alloy layer and the insulating film.

There is provided a method of making an active material with satisfactory cycle characteristics. The method of making an active material according to the invention comprises contacting an aqueous solution containing a metal-fluoro complex and lithium salt with lithium-containing metal oxide particles.

An intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent incorporated therein. The hydrogel polymer can be coated on the fiber elements in a co-axial configuration. The fiber elements may also have a second coating including a protective substance surrounding the hydrogel polymer having a therapeutic agent therein. The matrix of fiber elements can be formed by electrospinning. A process of delivering a therapeutic agent to a target site includes providing an intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent dispersed therein, and advancing the catheter device at a desired treatment site. Once at the desired treatment site, fluid is introduced into the inflation lumen to expand the expandable member from a first profile to a second profile, and the therapeutic agent is released from the hydrogel polymer and delivered to the desired treatment site.

A coated granule is obtained by coating a bioactive substance-containing granule with a urethane resin obtained by reaction of an aromatic diisocyanate with a polyol mixture containing a polyesterpolyol and a C2-C8 polymethylene glycol, wherein the molar ratio of the polyesterpolyol to the polymethylene glycol is 1:20 to 20:1. The granule is capable of controlling elution of the bioactive substance appropriately, and the urethane resin forming the coating film shows degradability in soil.