The invention relates to a methanol gasoline rubber anti-swelling agent and belongs to the field of alcohol ether fuel additives. The methanol gasoline rubber anti-swelling agent consists of 30 to 60 percent of fatty alcohol, 10 to 30 percent of calcium petroleum sulfonate, 8 to 20 percent of sulfonate, 7 to 18 percent of synthetic calcium sulfonate salt and 2 to 15 percent of alkylphenol calcium salt in percentage by weight. 0.012 to 0.028 percent of industrial product of the methanol gasoline rubber anti-swelling agent is added in methanol gasoline with different brands of between M15 and M100 and can reduce the volume swelling of the rubber by 40 to 46 percent. After methanol gasoline added with the methanol gasoline rubber anti-swelling agent is used in an automobile, the driving journey is 50,000 kilometers; compared with the methanol gasoline without methanol gasoline rubber anti-swelling agent, the test shows that the volume swelling of the rubber is reduced by 45 to 50 percent. Compared with lead-free gasoline, the test shows that the swelling rate of the methanol gasoline added with the methanol gasoline rubber anti-swelling agent is equal to that of the lead-free gasoline and achieves the equivalent effect with the lead-free gasoline. The methanol gasoline rubber anti-swelling agent has the characteristics of low cost, easy preparation, convenient use, good effect and the like.