90results about How to "Meet medication needs" patented technology

The invention provides a citicoline sodium tablet and a preparation method thereof. The citicoline sodium tablet provided by the invention contains citicoline sodium, starch, lactose, sodium carboxymethyl starch, 10% starch slurry and magnesium stearate. The prescription of a coating solution includes stomach-soluble coating powder and ethanol. The preparation method comprises the steps of: (1) preparation of an uncoated tablet: uniformly mixing main drugs with the lactose, grinding the mixture to pass through a 80-mesh sieve, respectively adding the starch and the sodium carboxymethyl starch and carrying out uniform mixing, passing through the 80-mesh sieve twice, adding the 10% starch slurry, adequately and uniformly mixing to prepare soft materials, carrying out pelletizing by utilizing a 20-mesh sieve, drying at 60 DEG C, adding the magnesium stearate, and carrying out uniform mixing, tabletting and testing; and (2) coating. The citicoline sodium tablet has the advantages of good stability, low cost, high active ingredient content and the like.

The invention discloses a culture method for ramulus uncariae cum uncis. The culture method comprises the following steps: firstly, culturing a ramulus uncariae cum uncis seed in a seed culture mediumfor 20-25d to obtain a sterile seedling hypocotyl; secondly, cutting a hypocotyl explant having the length of 0.4-0.8cm and containing no cotyledonary nodes from the sterile seedling hypocotyl, horizontally placing the hypocotyl explant in a first callus culture medium for dark culture for 20-25d, and then, transferring the hypocotyl explant into a second callus culture medium for dark culture toobtain a fresh callus; thirdly, transferring the fresh callus into a differential culture medium for differential culture to obtain a cluster bud; and fourthly, transplanting the cluster bud into a strong seedling culture medium for strong seedling culture, cutting off a basal part of a stem when the length of a single seedling is 3-4cm, transferring the seedling into a rooting culture medium forrooting culture, and growing a root with the length of 1.5-2.0cm to obtain a ramulus uncariae cum uncis seedling. The ramulus uncariae cum uncis obtained by using the culture method is purely natural, high in yield and high in medicinal component content.

The invention discloses eye gellan gum in-situ gel made of bendazac lysine. The eye gellan gum in-situ gel made of bendazac lysine is prepared from 0.4%-1% of bendazac lysine, 0.2%-0.6% of gellan gum, 2%-8% of osmotic pressure modifier, 0.05%-0.2% of pH modifier, 0.05%-0.4% of bacteriostatic agent, 0%-0.2% of thickening agent and the balance purified water, wherein the pH modifier is tromethamine. The eye gellan gum in-situ gel made of bendazac lysine is good in stasis capability on the cornea, convenient to apply and good in application prospect. The invention further discloses a preparing method of the eye gellan gum in-situ gel made of bendazac lysine. The method is easy and convenient to implement, easy to control and suitable for industrial production.

The invention discloses a pharmaceutical composition containing interferon and an application. Pharmacologically active ingredients of the pharmaceutical composition are the interferon and taurine, wherein an activity unit content of the interferon is 10 to 1x10<6> IU / mL, and a content of the taurine is 0.05-0.5 mg / ml. The pharmaceutical composition containing the interferon provided by the invention has effects of resisting activity of vesicular stomatitis virus and murine encephalomyocarditis virus, and protecting cells. Especially, each of nasal spray agent provided by the invention only has 50000 IU of alpha-2b recombinant human interferon and 1 mg of the taurine, but has a specific anti-viral activity of 9.15x10<5> to 2.8x10<6> IU, and shows substantial synergistic effect, thereby being significant for improving patient compliance and reducing medication costs, and meeting clinical needs of interferon medications.

The invention relates to a nanoparticle and polymer composite particle and an application thereof in the field of biomedicines. The nanoparticle and polymer composite particle is prepared from an organic monomer and inorganic nanoparticles through in-situ polymerization. In addition, the invention relates to an application of the nanoparticle and polymer composite particle as a coating or stable dispersion, and also relates to a composite emulsion system comprising a waterborne continuous phase and an oil phase, and the nanoparticle and polymer composite particle is obtained through mixing an aqueous dispersion of the composite particle with the oil phase and dispersing, wherein the volume of the oil phase is 1 / 100-100 times that of the aqueous dispersion. The invention also relates to a medicine-carrying composite emulsion system. The nanoparticle and polymer composite particle provided by the invention is favorable in dispersibility and stability in a water solution and wide in application in the field of biomedicines.

A dispersing tablet of famotidine features that on the basis of its chewing tablet, the special additives are used for it, such as excellent disintegrant (cross-linked povidone, sodium laurylsulfate, or microcrystal cellulose) and high-performance adhesive (povidone K30) are used in it. Its advantages are high disintegrating speed, high curative effect and high safety.

The invention provides a high-efficacy medicine supply method and device, a medium, and electronic equipment. The method comprises the steps: obtaining prescription information from each prescriptioninputted from a doctor's account, wherein the prescription information comprises the labels of medicines in the prescriptions and the account information of patients, so as to build the correspondingrelation between the medicines and the patients; receiving efficacy evaluation information which is inputted from the account of each patient and is corresponding to the labels of the medicines, so asto determine the efficacy of the medicines according to the evaluation of the patients; determining the high-efficacy medicine in all medicines according to the efficacy evaluation information corresponding to each medicine; determining the sum of the basic supply quantity and reserve quantity of the high-efficacy medicine as the inventory standard quantity of the high-efficacy medicine, determining the high-efficacy medicine according to the feedback of the patients, and carrying out the adjustment of the inventory standard quantity of the high-efficacy medicine, so as to enable the inventory of the high-efficacy medicine to meet the demands during the disease outbreak, and reduce the possibility of shortage of the high-efficacy medicine.

The invention discloses a semi-bionic preparation method for Xinkeshu preparations. The preparation method comprises steps as follows: (1), costus roots are taken, ground, mixed with water, heated and subjected to reflux distillation, preliminary distillate is collected, redistillation is performed, volatile oil is extracted and the distillate is filtered; (2), other raw materials are taken and combined with medicine residues in the step (1), water with the pH (potential of hydrogen) value being 2.0-2.5 is added, and the mixture is heated, extracted and filtered; (3), water with the pH being 6.5-7.0 is added to medicine residues obtained in the step (2), and the mixture is heated, extracted and filtered; (4), water with the pH value being 7.8-8.5 is added to medicine dregs obtained in the step (3), and the mixture is heated, extracted and filtered; (5), filtrate obtained in the steps (2), (3) and (4) is combined and concentrated until an ointment is obtained, the ointment is granulated, dried and mixed with the volatile oil obtained in the step (1), a carrier or an auxiliary material acceptable in pharmaceutics is added, and medicine preparations are prepared. The content of effective ingredients of the Xinkeshu preparations prepared with the method is substantially increased, and the Xinkeshu preparations have higher bioavailability and are better absorbed by human bodies.

The invention relates to a Tibetan medicine, and particularly relates to a Tibetan-medicine three-component Tibet inula soup-granula composition and a preparation process thereof. The composition disclosed by the invention is prepared from the following raw materials in parts by weight: Ramulus Rubi, Tinospora sinensis and Tibet inula in a proportion of 2:1:1. The preparation process comprises the following steps: 1) carrying out superfine grinding on the Tibet inula; 2) placing the Tinospora sinensis and the Ramulus Rubi in a multifunctional extraction pot to decoct, filtering and concentrating to obtain an aqueous extract, and drying the aqueous extract by using a centrifugal spray drier; 3) combining dry cream powder with micro-powder; and 4) adding ethanol into the obtained powder, preparing into a soft material, granulating the soft material by using a granulator, drying, and carrying out straightening granulation to obtain the composition. According to the composition disclosed by the invention, when the quality of Tibetan medicines is improved, due to the reference and introduction of some new processes, new techniques and new devices, the stability and bioavailability of preparations can be improved, and traditional Tibetan medicine and modern preparation methods are combined, thus a way for the rational development of Tibetan medicines is explored.

The invention relates to the technical field of medicines, in particular to a preparation method of artificial bear bile dripping pills. The preparation method comprises the following steps of S1, performing crushing, weighing and blending on raw materials: crushing artificial bear bile powder with a universal crushing machine, performing screening, and performing sealing for standby application;S2, performing compounding and heat preservation: heating oil bath to the temperature of 60-95 DEG C, adding polyethylene glycol 6000 to a blending jar in several times, wherein the addition quantityeach time is 2-20kg, performing heating and stirring for melting, after the polyethylene glycol completely melts, performing stirring, adding the crushed artificial bear bile powder, performing mixingto obtain cream which is dark pale brown to dark brown, and putting the compounded materials to be dripped in the blending jar for heat preservation; and S3, preparing dripping pills: adding 50-300kgof light weight liquid paraffin to a pill dripping machine as a condensing agent, wherein the temperature of oil bath in the pill dripping machine rises to 60-95 DEG C, adding materials to be drippedinto a seasoning jar, and performing dripping with 2.5# dripping heads of 1 row of dripping trays. According to the preparation method disclosed by the invention, the artificial bear bile powder is used as a raw material medicine, an artificial bear bile dripping pill preparation is developed, and the problem that natural bear bile raw materials are valuable and scarce is solved.

The invention discloses a liquid composition comprising an antibody of human interleukin-4 receptor alpha. The liquid composition comprises the antibody at a concentration of 50-200 mg / ml, a buffer agent, a protective agent and a surfactant, wherein the buffer agent, the protective agent and the surfactant serve as auxiliary materials, and the liquid composition has pH of 5.4 to 6.4. When the pharmaceutical composition is used for subcutaneous injection or intravenous injection, the high-dose antibody can be provided, the administration requirement is met, and the curative effect of a medicineis improved.

The invention discloses o an oral tablet of acotiamide hydrochloride trihydrate and a preparation method thereof. The acotiamide hydrochloride trihydrate disclosed by the invention adopts a water insoluble filler as the first filler, and aims to still maintain the original particle shape when drug particles contact a dissolution medium and other solutions so as to prevent acotiamide hydrochloride from gathering, thus achieving a good dissolution effect. At the same time, through additional adding of a second filler and a disintegrating agent, the material is ensured with good compressibility and dissolution performance. According to the acotiamide hydrochloride tablet and the preparation method provided by the invention, the operation is simple, the dosage of auxiliary materials is significantly reduced, the tablet weight is small, and while the dissolution rate is guaranteed, the patient compliance is also improved.

The invention belongs to the technical field of tobacco pesticide application control, and discloses a control method, system and device for accurately applying pesticide to tobaccos and application.A speed control wheel is used for accurately applying the pesticide to the tobaccos, and corresponding hardware devices and matched operation parameters are adopted for different development stages ofthe tobaccos; accessories such as a flow control main board, a multi-stage spray head and a horizontal auxiliary wheel are matched for use to reduce a spraying blank area or an invalid area of the prevention and treatment pesticide; an adjustable pressure pump determines the effective application range of the pesticide through the constant pesticide box pressure; the flow control device adjusts the pesticide flow at any time according to the change of the step speed of an operator through the step speed monitoring of the operator; the multi-stage spray head and the horizontal auxiliary wheelmeet the special requirements of pest control in different growth periods of the tobaccos; and the flow control mainboard only needs to input simple data information to complete parameter configuration of the whole system. The requirements of current precise pesticide application technicians, instruments, sites and the like are reduced, and the requirements of different tobacco planting productionareas can be met.

A dispersing tablet of famotidine features that on the basis of its chewing tablet, the special additives are used for it, such as excellent disintegrant (cross-linked povidone, sodium laurylsulfate, or microcrystal cellulose) and high-performance adhesive (povidone K30) are used in it. Its advantages are high disintegrating speed, high curative effect and high safety.