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Notoginseng vulnerary extract and method for making same and application

A medicine extract and extract technology, applied in the field of notoginseng wound medicine extract and its preparation, can solve the problems of prone to adverse reactions, large dosage, and limited application range, so as to increase the use, meet the needs of medicine, and The effect of reducing the effect

Inactive Publication Date: 2007-12-05
YUNNAN PHYTOPHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, Radix Notoginseng has a strong medicinal property, and the prior art has a relatively large dose because of adding some crude drugs, three tablets at a time, three times a day; three capsules at a time, three times a day; Contains raw powder of some medicinal materials and is only suitable for oral preparations. For the elderly, children or people with poor gastrointestinal function, adverse reactions are prone to occur; and it can only be taken internally, and the scope of application is very limited

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0152]Example 1: Weigh the components of Radix Notoginseng wound medicine: 52.5 grams of Radix Notoginseng, 52.5 grams of Aconitum Aconitum (steamed), 23 grams of Artemisia annua, 1.05 grams of Borneolum, 492.2 grams of Rhizoma Drynariae, 157.5 grams of Safflower, 787.5 grams of wood, 87.5 grams of Radix Paeoniae Rubra; the components of the notoginseng wound medicine were pulverized respectively, passed through a 10-60 mesh sieve, mixed evenly (except borneol), and extracted 3 times by adding 50%-95% ethanol. Use 8-3 times the amount of ethanol once, use 6-10 times the amount of ethanol for the second time, and use 4-8 times the amount of ethanol for the third time; collect the extract, concentrate it into a liquid extract, add borneol and mix well to get Panax notoginseng Wound medicine extract (borneol can also be added when preparing the preparation), or concentrated into a thick paste, and dried to obtain the notoginseng wound medicine extract;

Embodiment 2

[0153] Embodiment 2: Weigh each component of the notoginseng wound medicine, the extraction solvent is water, and other steps are the same as in embodiment 1;

Embodiment 3

[0154] Embodiment 3: take by weighing each component of notoginseng wound medicine, pulverize respectively, pass 10-60 mesh sieve, add the ethanol extraction of 50%-95% respectively 3 times, the ethanol consumption of the first time is 8-13 times the amount, the second Use 6-10 times the amount of ethanol for the first time, and 4-8 times the amount of ethanol for the third time; collect the extract, concentrate it into a fluid extract, and then mix the resulting fluid extract (or concentrate into a thick paste, dry, pulverize, mix), then add borneol and mix (borneol can also be added when preparing the preparation), to obtain the extract of notoginseng;

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Abstract

The present invention is Notoginseng Vulnerary extract and its preparation process and application. All the ingredients of Notoginseng Vulnerary except borneol are extracted to obtain the effective components, and the extracted effective components together with borneol are prepared into different dosage forms for both orally taking and external applying. The present invention expands the application range of Notoginseng Vulnerary.

Description

technical field [0001] The invention relates to the technical field of pharmaceuticals, in particular to the extract of notoginseng medicinals, its preparation method and its application in various dosage forms for external use and internal administration. Background technique [0002] The existing tablets or capsules of notoginseng wound medicine are some crude drugs (notoginseng, aconitum, Artemisia mellifera) crushed into fine powder, borneol is ground into fine powder, and the rest of the crude drugs (drynaria rhizome, safflower, elderberry, Radix Paeoniae Rubra) is extracted by adding water to make a clear ointment; add Sanqi, Aconitum Aconitum, and Artemisia spp. fine powder to make granules, dry, add borneol fine powder and mix well; it is an agent for dredging collaterals and dispersing blood stasis, and has the effect of relaxing tendons and activating blood circulation , the function of dissipating blood stasis and relieving pain; used for bruises, rheumatic stasis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714A61P29/00A61P19/02A61P19/04A61K31/045
Inventor 周敏黄春球朱红涛
Owner YUNNAN PHYTOPHARML
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