Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
33 results about "Vesicular Stomatitis" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
A viral disease caused by at least two distinct species (serotypes) in the VESICULOVIRUS genus: VESICULAR STOMATITIS INDIANA VIRUS and VESICULAR STOMATITIS NEW JERSEY VIRUS. It is characterized by vesicular eruptions on the ORAL MUCOSA in cattle, horses, pigs, and other animals. In humans, vesicular stomatitis causes an acute influenza-like illness.
Reagent box for detecting aftosa A type, O type and Asia 1 type viruses and preparing method thereof
ActiveCN104195268AMicrobiological testing/measurementMicroorganism based processesSwine vesicular diseaseElectrophoresis
The invention discloses a primer capable of being used for detecting aftosa A type, O type and Asia 1 type viruses, a reagent box comprising the primer and a preparing method thereof. Six gene sequences are available in the primer for detecting the aftosa A type, O type and Asia 1 type viruses, and two universal primers are additionally arranged. Related experiments show that the nucleic acids of the aftosa A type, O type and Asia 1 type viruses can be specifically and rapidly amplified by the primer sequences, and a specific strip is detected by nucleic acid electrophoresis, but the nucleic acids of vesicular stomatitis viruses and swine vesicular disease viruses cannot be amplified under the same conditions. The primer can be used for rapidly identifying the aftosa A type, O type and Asia 1 type viruses and applied in the epidemiological research of aftosa viruses.
Owner:LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
Development and application of multiple fluorescence RT-PCR detection method for foot-and-mouth disease, vesicular stomatitis and swine vesicular disease
InactiveCN103602757AMicrobiological testing/measurementMicroorganism based processesSwine vesicular diseaseAnimal virus
Based on a highly conserved domain of a foot-and-mouth disease virus 3D protein coding gene, a vesicular stomatitis virus N protein coding gene and a swine vesicular disease virus VP1 protein coding gene, the invention designs a specific primer and a probe and develops a multiple fluorescence RT-PCR detection method used for simultaneously detecting the three animal viruses. The detection method can detect 102 copied plasmids containing target amplification sequences in 1 h. The method has high sensitivity and good specificity, and can achieve rapid high-throughput fluorescence RT-PCR detection for single-virus infection or mixed infection by a plurality of viruses.
Owner:ANIMAL & PLANT & FOOD INSPECTION CENT OF TIANJIN ENTRY EXIT INSPECTION & QUARANTINE BUREAU
Infection and treatment of neoplasms with vesicular stomatitis virus
InactiveUS8043612B2Convenient treatmentIncreased interferon sensitivityOrganic active ingredientsVirusesDiseaseDna viral
Owner:WELLSTAT BIOLOGICS CORP
Preparation method of composite feed additive and anti-virus agent and application of anti-virus agent
InactiveCN107821739AImprove disease resistanceRich in nutrientsOrganic active ingredientsHeavy metal active ingredientsBiotechnologyAnti virus
The invention discloses a preparation method of a composite feed additive and the composite feed additive prepared with the preparation method, further discloses a method for preparing an anti-virus agent from the composite feed additive, and the anti-virus agent, and further discloses application of the anti-virus agent in inhibiting vesicular stomatitis viruses and application in preventing animal cells from infection of the vesicular stomatitis viruses. The invention has the beneficial effects that 1, due to mixing and fermentation of two bacteria, namely brewer's yeast and methyl nutritional type bacillus, the composite feed additive is relatively rich in nutrient component and active bacterium, is capable of greatly improving the disease resistance of animals, and has great significances in livestock feeding and feed industry; 2, the anti-virus agent is a composite feed additive lixivium, and has remarkable activity and proliferation inhibition upon VSVs (Vesicular Stomatitis Viruses); 3, the anti-virus agent is capable of effectively preventing animal cells from VSV infection.
Owner:河南邑鸿善成生物技术有限公司
Vaccines against vesicular stomatitis
Owner:MERIAL INC
Kit for detecting vesicular stomatitis antibody and preparation method thereof
The invention relates to a kit for detecting vesicular stomatitis antibody and a preparation method thereof. The kit for detecting vesicular stomatitis antibody comprises a reagent I and a reagent II placed respectively, wherein the reagent I is a vesicular stomatitis virus antihelion peridium enzyme linked immunosorbent assay plate and the reagent II is monoclonal antibody IgG-HRP enzyme conjugates, wherein the monoclonal antibody IgG-HRP enzyme conjugates is idiocrasy monoclonal antibody of mouse-anti vesicular stomatitis virus of horse radish peroxidase mark. The invention also provides a preparation method of the kit. The kit adopts competitive ELISA to detect the vesicular stomatitis in serum, and can be used for rapid diagnosis, detection, quarantine and epidemiological investigation of vesicular stomatitis.
Owner:花群义
Vesicular disease detection kit
ActiveCN104789694AReduce analysis costsShorten experiment timeMicrobiological testing/measurementDNA/RNA fragmentationSwine vesicular diseaseMicrobiology
The invention discloses primers which can be used for detecting aftosa (type A, type O, and type Asia 1), swine pox and vesicular stomatitis at the same time, a kit consisting of the primers and a preparation method, and a use method of the kit for a dis-illness diagnosis purpose. The invention provides 10 gene sequences of the primers for detecting type A, type O, and type Asia 1 viruses of aftosa, and the kit further comprises two general primers besides the ten primers. Related experiments show that sensitivity of the use method in the invention is higher than sensitivity of general fluorogenic quantitative PCR technology. Compared with the fluorogenic quantitative PCR technology, the detection time is greatly saved; augmentation of non-specific products is avoided; phenomenon of preferences of primers is effectively avoided; and detection sensitivity is improved.
Owner:LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
Vaccines against vesicular stomatitis
The present invention relates to an immunogenic or vaccine composition to induce an immune response or protective immune response against vesicular stomatitis virus (VSV) in an animal susceptible to VSV. The composition may include a pharmaceutically or veterinarily acceptable vehicle or excipient, and a vector. The vector may contain at least one heterologous nucleic acid molecule(s), expresses in vivo in the animal VSV antigen(s), immunogen(s) or epitope(s) thereof, e.g., VSV G protein and / or VSV N protein and / or VSV M protein. The heterologous nucleic acid molecule(s) may be adjusted to the vector / mammalian cell system by codon optimization. The composition can contain an adjuvant, such as carbomer. Methods for making and using such a composition, including prime-boost regimes and including as to differential diagnosis, are also contemplated.
Owner:MERIAL INC
Gene chip and kit used for detecting foot and mouth disease viruses, vesicular stomatitis viruses and swine vesicular disease viruses
InactiveCN105018641AGrasp the infection situation quicklyStrong specificityMicrobiological testing/measurementMicroorganism based processesSwine vesicular diseaseFoot mouth disease virus
The invention discloses a gene chip and kit used for detecting foot and mouth disease viruses, vesicular stomatitis viruses and swine vesicular disease viruses. The gene chip and kit and a detection method provided by the invention can accurately and effectively detect foot and mouth disease viruses, vesicular stomatitis viruses and swine vesicular disease viruses and have the advantages of high specificity and sensitivity, short detection time, rapid detection and good application prospects.
Owner:SICHUAN AGRI UNIV
Attenuated virus vector system, application of attenuated virus vector system in preparation of anti-malignant tumor drugs and drug use method
InactiveCN110564767ALittle or no specific serum antibodiesRealize large-scale productionSsRNA viruses negative-senseUnknown materialsSingle-Chain AntibodiesMammal
The invention discloses an attenuated virus vector system, an application of the attenuated virus vector system in preparation of anti-malignant tumor drugs and a drug use method. The virus is RNA virus, its genetic material does not have integration capability in the mammalian cells, and the virus belongs to the field of rhabdoviridae and vesicular stomatitis viruses. The virus vector system structure gene chimeric coding molecule at least comprises an inhibitor specific to an immune checkpoint molecule, the attenuated virus vector system is a novel recombinant expression vector system for chimeric expression of a single-chain antibody aiming at an immune checkpoint, the replication can be specifically completed in tumor cells, and meanwhile, specific antibodies secreting molecules binding to the surfaces of the tumor cells can be expressed, the tumor antigen is released, the anti-tumor specific immune response of immune cells is activated at the same time, meanwhile, the secreted single-chain antibody breaks the immunosuppressive effect of the tumor microenvironment, the removal of CTL cells to tumor cells is promoted, a systematic specific anti-tumor immune memory reaction of anorganism is promoted, and the recurrence of tumors is controlled.
Owner:董春升
Pharmaceutical composition for treating tumors or cancers and application thereof
InactiveCN111494432ABreak inhibitionPromote specific killingUnknown materialsAntibody ingredientsGenes mutationAntiendomysial antibodies
The invention relates to a pharmaceutical composition for treating tumors or cancers and application thereof, in particular to a pharmaceutical composition which comprises vesicular stomatitis virusesdelivered through direct injection or systemic administration or intratumoral delivery and is combined with PDL1 antibody intravenous administration to generate a synergistic effect in treatment of metastatic lung cancer. Besides, the oncolytic virus after gene mutation and the PDL1 antibody have the characteristic of recognizing tumor cells, normal cells are not damaged, and the oncolytic virusand the PDL1 antibody are sequentially combined for use to generate a synergistic effect in curative effect.
Owner:FANTASIA BIOPHARMA ZHEJIANG CO LTD
A kind of recombinant N protein antigen of vesicular stomatitis virus and its preparation method
InactiveCN105334322BGood antigenicityGood effectMaterial analysisNucleotideVesicular stomatitis virus VSV
Owner:SHENZHEN AUDAQUE DATA TECH
Recombinant VSV for the treatment of tumor cells
InactiveUS20140088177A1SsRNA viruses negative-sensePeptide/protein ingredientsInfected cellAbnormal cell
Vesicular Stomatitis Viruses expressing foreign nucleic acid sequences were highly attenuated but were lytic for abnormal cells, such as cancers, infected cells. Methods of treatment include the administration of these viruses.
Owner:UNIV OF MIAMI
Primer and kit for detecting vesicular stomatitis viruses and preparation method of kit
The invention discloses a primer for detecting vesicular stomatitis viruses, a detection kit composed of the primer and a preparation method of the detection kit. The primer for detecting the vesicular stomatitis viruses has gene sequences, namely SEQ ID No.1, SEQ ID No.2, SEQ ID No.3 and SEQ ID No.4. A related experiment shows that a nucleic acid of the VSV can be specifically and rapidly amplified by the primer sequence and a specific band can be detected by nucleic acid electrophoresis; and meanwhile, the primer has the specificity. The primer can be applied to preparation of a GeXP diagnostic kit for rapidly identifying the VSV and applied to epidemiologic studies of vesicular stomatitis.
Owner:LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
Modified matrix proteins of vesicular stomatitis virus
ActiveUS20160144022A1Reduce releaseReduce in quantitySsRNA viruses negative-senseSsRNA viruses positive-senseAntigenGlycine
The present invention relates to vesicular stomatitis virus (VSV) matrix (M) protein mutants. One mutant M protein includes a glycine changed to a glutamic acid at position (21), a leucine changed to alanine at position (111) and a methionine changed to an arginine at position (51). Another M protein mutant includes a glycine changed to a glutamic acid at position (22) and a methionine changed to an arginine at positions (48) and (51). These new rVSVs having the mutant M are significantly attenuated and lost virulence, including neurovirulence, and are capable of inducing an immune responses against an antigen of interest. In addition, a rVSV serotype Indiana having the first described M mutant is capable of efficient replication at 31° C., and of poor replication or incapable of replication at about 37° C. or higher.
Owner:UNIV OF WESTERN ONTARIO
Vesicular stomatitis virus for prime boost vaccine
ActiveUS20140370043A1Reduce releaseAttenuated and avirulentSsRNA viruses negative-senseSsRNA viruses positive-senseAntigenArginine
The present invention relates to vesicular stomatitis virus (VSV) matrix (M) protein mutants. One mutant M protein includes a glycine changed to a glutamic acid at position (21), a leucine changed to a phenylalanine at position (111) and a methionine changed to an arginine at position (51). Another M protein mutant includes a glycine changed to a glutamic acid at position (22) and a methionine changed to an arginine at positions (48) and (51). Yet another VSV M protein mutant includes a glycine changed to a glutamic acid at position (22), a leucine changed to a phenylalanine at position (110) and a methionine changed to an arginine at positions (48) and (51). The present invention is directed also to recombinant VSVs (rVSV) having these M mutants and to vaccines based on the rVSV having the M mutants of the present invention. These new rVSVs having the mutant M were significantly attenuated and lost virulence, including neurovirulence, and are capable of inducing an immune responses against an antigen of interest. In addition, a rVSV serotype Indiana having the first described M mutant is capable of efficient replication at 31° C., and of poor replication or incapable of replication at about 37° C. or higher.
Owner:UNIV OF WESTERN ONTARIO
Vesicular stomatitis virus recombinant N protein antigen, and preparation method thereof
The invention belongs to the technical field of gene engineering, and more specifically relates to a vesicular stomatitis virus recombinant N protein antigen, and a preparation method thereof. The amino acid sequence of the vesicular stomatitis virus recombinant N protein antigen is represented by SEQ ID No.1; and the nucleotide sequence of a gene used for coding the vesicular stomatitis virus recombinant N protein antigen is represented by SEQ ID No.2. The vesicular stomatitis virus recombinant N protein antigen is used for preparing test strips used for rapid detection of vesicular stomatitis virus antibodies; specificity and sensitivity are high; detection is rapid; operation is simple; detection sample amount is small; detection cost is relatively low; and an excellent detection method is provided for vesicular stomatitis virus antibody detection and vesicular stomatitis epidemiological investigation.
Owner:SHENZHEN AUDAQUE DATA TECH
Liquid-phase protein chip kit for simultaneously detecting four types of foreign and new animal diseases and preparation method thereof
The invention discloses a liquid-phase protein chip kit for simultaneously detecting four types of foreign and new animal diseases. Four types of activated fluorescent magnetic microspheres are respectively coupled with the expressed, purified and verified peste des petits ruminants virus protein (PPRV-N), vesicular stomatitis virus protein (VSV-N), schmallenberg virus protein (SBV-N) and bluetongue virus protein (BTV-VP7). The liquid-phase protein chip kit has the characteristics that the four types of foreign and new animal diseases, such as peste des petits ruminants, vesicular stomatitis,schmallenberg and bluetongue, can be simultaneously detected; the parallel detection effect is realized, and the flux is high; about 400 items of 100 samples can be completed each time; the operationis simple, the time is short, and the detection can be completed within 1h or above; the usage amount of samples is small, and multiple items can be detected by only using 0.1 to 1mu L of serum; the specificity and sensitivity are good.
Owner:贾赟
Gene chip for detecting 6 viruses of zoonosis-borne diseases and application thereof
InactiveCN102031311BStable and specific universal detectionStable and specific realization of universal detectionNucleotide librariesMicrobiological testing/measurementFoot mouth disease virusRabies virus
Owner:MICROBE EPIDEMIC DISEASE INST OF PLA MILITARY MEDICAL ACAD OF SCI
Gene chip of vesicular stomatitis viruses and/or swine vesicular disease viruses and reagent kit
InactiveCN105002565AMaster fastStrong specificityNucleotide librariesMicrobiological testing/measurementVesicular StomatitisSwine vesicular disease
The invention discloses a gene chip of vesicular stomatitis viruses and / or swine vesicular disease viruses and a reagent kit. By means of the gene chip, the detection reagent kit and a detection method, the vesicular stomatitis viruses and / or the swine vesicular disease viruses can be accurately and effectively detected. Besides, the gene chip and the detection reagent kit are high in specificity and sensitivity, low in time consumption, high in detection speed and good in application prospect.
Owner:SICHUAN AGRI UNIV
A detection kit capable of simultaneously detecting and differentiating foot-and-mouth disease and vesicular stomatitis, as well as primers and probes
ActiveCN106929605BGuaranteed FeaturesGuaranteed exclusivityMicrobiological testing/measurementMicroorganism based processesMultiplexDisease
The invention discloses a detection kit, primer and probe capable of simultaneously detecting and identifying a foot-and-mouth disease and vesicular stomatitis. The primer and the probe are shown as sequence tables SEQ ID NO:1 to SEQID NO:14. The invention further discloses a one-step-method multiplex fluorescence RT-PCR detection kit rapid, accurate and convenient to use and simultaneously detecting and identifying the foot-and-mouth disease and the vesicular stomatitis. By adopting the detection method, one-time sampling and one-time analysis can be achieved, the purpose of simultaneously detecting and distinguishing three types of important viruses can be achieved, the working amount and cost for detection is reduced, epidemic disease detection can be completed within the shortest time, and time is won for disease prevention and treatment.
Owner:中国海关科学技术研究中心
Primers, kit and preparation method for detecting vesicular stomatitis virus
The invention discloses a primer for detecting vesicular stomatitis viruses, a detection kit composed of the primer and a preparation method of the detection kit. The primer for detecting the vesicular stomatitis viruses has gene sequences, namely SEQ ID No.1, SEQ ID No.2, SEQ ID No.3 and SEQ ID No.4. A related experiment shows that a nucleic acid of the VSV can be specifically and rapidly amplified by the primer sequence and a specific band can be detected by nucleic acid electrophoresis; and meanwhile, the primer has the specificity. The primer can be applied to preparation of a GeXP diagnostic kit for rapidly identifying the VSV and applied to epidemiologic studies of vesicular stomatitis.
Owner:LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
Method for inactivating vesicular stomatitis viruses
ActiveCN111117976ANo toxicityEasy to inactivateSsRNA viruses negative-senseInactivation/attenuationHeminHematine
The invention relates to a method for inactivating vesicular stomatitis viruses. Thus, hematin can contact with vesicular stomatitis viruses. A reagent for inactivating the vesicular stomatitis viruses is also related. The reagent includes alkali, hemin and solvents, wherein the mass percentage concentration of the alkali is 0.01-0.1%, and the feeding mass percentage concentration of the hemin is0.001-0.1%. The reagent has no toxicity to cells and can well inactivate the vesicular stomatitis viruses; and the method is simple and can remove added inactivation reagents without post-processing operation.
Owner:苏州良辰生物医药科技有限公司
A kind of test kit for blister venereal disease
ActiveCN104789694BIncreased sensitivityReduce cross contaminationMicrobiological testing/measurementDNA/RNA fragmentationMicrobiologyPcr ctpp
Owner:LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
Therapeutic flavonoid based antiviral agents
The world is plagued with several viruses some of which have prevention and treatment tools available, while every so often a new strain will show up without sensitivity to existing drugs. The present invention provides plant-based flavonoid pharmaceutical compositions for inhibition of kinases, particularly phosphatidylinositol-4-kinases (PI4Kiiiβ), AAK1, BIKE, GAK and other transcription factors required for viral entry, replication and survival, and consequent for prevention and treatment of RNA viruses including but not limited to adenoviruses, alphaviruses, coronaviruses, enteroviruses, flaviviruses, hepatitis, herpes, influenza viruses, measles, picornaviruses, vesicular stomatitis and associated disorders. A method for synthesizing the flavonoids and formulation into therapeutic products are also disclosed.
Owner:LOWE HENRY C +2
Detection kit, primer and probe capable of simultaneously detecting and identifying foot-and-mouth disease and vesicular stomatitis
ActiveCN106929605AGuaranteed FeaturesGuaranteed exclusivityMicrobiological testing/measurementMicroorganism based processesFluorescenceBioinformatics
The invention discloses a detection kit, primer and probe capable of simultaneously detecting and identifying a foot-and-mouth disease and vesicular stomatitis. The primer and the probe are shown as sequence tables SEQ ID NO:1 to SEQID NO:14. The invention further discloses a one-step-method multiplex fluorescence RT-PCR detection kit rapid, accurate and convenient to use and simultaneously detecting and identifying the foot-and-mouth disease and the vesicular stomatitis. By adopting the detection method, one-time sampling and one-time analysis can be achieved, the purpose of simultaneously detecting and distinguishing three types of important viruses can be achieved, the working amount and cost for detection is reduced, epidemic disease detection can be completed within the shortest time, and time is won for disease prevention and treatment.
Owner:中国海关科学技术研究中心
Establishment and application of multiplex fluorescent RT-PCR detection method for foot-and-mouth disease, vesicular stomatitis and porcine vesicular disease
InactiveCN103602757BMicrobiological testing/measurementMicroorganism based processesAnimal virusSwine vesicular disease
Based on a highly conserved domain of a foot-and-mouth disease virus 3D protein coding gene, a vesicular stomatitis virus N protein coding gene and a swine vesicular disease virus VP1 protein coding gene, the invention designs a specific primer and a probe and develops a multiple fluorescence RT-PCR detection method used for simultaneously detecting the three animal viruses. The detection method can detect 102 copied plasmids containing target amplification sequences in 1 h. The method has high sensitivity and good specificity, and can achieve rapid high-throughput fluorescence RT-PCR detection for single-virus infection or mixed infection by a plurality of viruses.
Owner:ANIMAL & PLANT & FOOD INSPECTION CENT OF TIANJIN ENTRY EXIT INSPECTION & QUARANTINE BUREAU
Test kit for epidemic prevention of black cattle and preparation method thereof
InactiveCN111979114AImprove detection efficiencyAvoid residueBioreactor/fermenter combinationsBiological substance pretreatmentsFoot mouth disease virusVesicular stomatitis virus VSV
The invention discloses a test kit for epidemic prevention of black cattle and a preparation method thereof. The test kit comprises a detection box body, detection tubes, pressing pistons and samplingneedles, wherein the detection box body is cylindrical; a rotating rod is arranged in and rotationally connected with the detection box body; a knob is fixed to the upper end of the rotating rod; fixed rods are fixed to the side faces of the rotating rod; fixed sleeves are fixed to the ends, away from the rotating rod, of the fixed rods; three fixed rods are in the circumferential direction of the rotating rod; the detection tubes are placed in the two fixed sleeves; each detection tubes is internally connected with the corresponding pressing piston in a sliding mode; and the outer wall of the detection box body is transparent. The detection kit disclosed by the invention can be used for simultaneously detecting various diseases, including main diseases of black cattle, such as foot-and-mouth disease viruses, vesicular stomatitis viruses, bovine lumpy skin disease viruses and the like; the detection efficiency of the kit is high; and meanwhile, the whole structure of the kit is convenient to disassemble, the kit is convenient to clean after detection, pathogen residues can be prevented, and a detection structure is accurate.
Owner:WEIFANG YOURONG IND
Mutant vsv ectodomain polypeptide and uses thereof
PendingUS20220162266A1Stable formEasy to identifySsRNA viruses negative-senseVirus peptidesGlycoprotein GOrganic chemistry
The present invention relates to a mutant polypeptide comprising the amino acid sequence of the ectodomain of glycoprotein G of a vesicular stomatitis vims (VSV) strain, wherein said ectodomain comprises the amino acid sequence as set forth in SEQ ID NO: 2 or a sequence having at least 50% of identity with the amino acid sequence as set forth in SEQ ID NO: 2, with at least one substitution of an amino acid residue selected from the group consisting of: a) any amino acid residue located from position 421 to position 429 and any amino acid residue located from position 17 to position 25 of SEQ ID NO:2; or b) any amino acid residue located from a position equivalent to position 421 to a position equivalent to position 429 of SEQ ID NO: 2 and any amino acid residue located from a position equivalent to position 17 to a position equivalent to position 25 of SEQ ID NO: 2, after optimal global alignment with SEQ ID NO:2.
Owner:CENT NAT DE LA RECHERCHE SCI +1
Carboxamide compound and application thereof
ActiveCN110467593ALow biological toxicity effectEffectively control cell diseaseOrganic chemistryAntiviralsCytopathic effectLarge dose
The invention relates to a carboxamide compound and application thereof, belonging to the technical field of preparation of drugs used for preventing and treating animal viral epidemic diseases. The carboxamide compound disclosed by the invention is 2-imino-2H-chromene-3-carboxamide, and the structural formula of the carboxamide compound is shown in the specification. The carboxamide compound disclosed by the invention has no obvious biotoxicity, can effectively control the proliferation of vesicular stomatitis viruses in BHK21 cells at a low dose, delays the occurrence of cytopathic effect, is capable of completely blocking the proliferation of viruses at a large dose, wins over a time window for the prevention and control of epidemic diseases caused by the vesicular stomatitis viruses, and provides a new drug for the treatment of affected individuals.
Owner:LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com