Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

112results about How to "Help to enter" patented technology

Inserted tooth hammer of crushing machine and preparation method thereof

The invention relates to an inserted tooth hammer of a crushing machine and a preparation method thereof and belongs to the fields of high technology engineering materials and application thereof. The inserted tooth hammer of the crushing machine consists of ball teeth and a hammer base body and is formed by virtue of high temperature imbedding, wherein the ball teeth are novel high-hardness high-strength anti-abrasive composite metal ceramic comprising one or more of WC, TiN or TiC based composite metal ceramic; the hammer base body is middle-low carbon steel or alloy steel with high hardness and strength and good toughness; the inserted tooth hammer of the crushing machine structurally comprises multiple cylindrical ball teeth with spherical crowns, the multiple cylindrical ball teeth are imbedded at the front end of the hammer base body, a cylinder is buried in a steel body, the spherical crowns are exposed out of the steel body, and a distance is reserved between the ball teeth. The preparation method of the inserted tooth hammer of the crushing machine successively comprises the following steps of: pre-preparing composite metal ceramic ball teeth; smelting hammer base body alloy steel; imbedding the ball teeth; and demoulding. The inserted tooth hammer of the crushing machine has the characteristics of good abrasive resistance, long service life, raw material economization and low cost.
Owner:CHINA UNIV OF GEOSCIENCES (BEIJING)

Pretreatment liquid for direct injection of polyester fiber through dispersive ink and direct injection digital printing process

The invention discloses a pretreatment liquid for direct injection of polyester fiber through dispersive ink and a direct injection digital printing process. The pretreatment liquid comprises, by mass, 0.2-5 parts of thickener, 1-10 parts of dispersion promoter, 2-5 parts of sodium chloride and 76-95 parts of water. The pretreatment liquid is semi-thick liquid, polyester fabric after going through impregnation or padding treatment liquid is dried, injection printing of dispersive dye ink is performed, high-temperature steaming baking is performed for color fixing after drying, water washing is performed, and then drying is performed to obtain a printing finished product. The pretreatment liquid is simple to prepare, convenient to use and suitable for direct injection process digital printing of all fabric high in polyester content, and the pretreatment liquid is easy to wash away after printing, so that hand feel of fabric is unaffected. Conventional heat transfer printing is replaced by the dispersive direct injection process, and transfer printing paper is not used, so that the direct injection digital printing process is environment-friendly. The pretreatment liquid can effectively prevent ink from spreading around on the polyester fabric, so that patters are ensured to be exquisite and lines are ensured to be clear after printing; color yield rate is high, printing is saturated and bright in color, and visual three-dimensional sense is high.
Owner:深圳市墨库图文技术有限公司

Composite dipper tooth of excavator and manufacturing method thereof

The invention relates to a composite dipper tooth of an excavator and a manufacturing method thereof, belonging to the field of high-tech engineering materials and application thereof. The novel composite dipper tooth comprises two parts of a bar type tooth tip (tooth bar) and a dipper tooth substrate (tooth substrate) and is formed by high temperature casting. The tooth bar material is novel high-rigidity and high-strength composite metal ceramics and comprises one or more of WC, TiCN, TiN or TiC-based composite metal ceramics; the tooth substrate is high / low chrome alloy steels or high manganese steels with higher rigidity and strength; a composite dipper tooth structure comprises a plurality of tooth bars of wedge shapes, the tooth bars are embedded at the front end of the tooth substrate, and a small section of each tooth bar is exposed out of a steel body, and a certain distance is arranged between tooth bars. The manufacturing method of the composite dipper tooth of the excavator sequentially comprises the following steps of: prefabricating the tooth bars; smelting alloy steels; casting the composite dipper tooth; and demolding. The tooth bar material is characterized by high rigidity, high strength and wearing resistance; the wearing resistance of the dipper tooth is improved and the consumption of wearing materials is reduced due to an intermittent structure, raw materials are saved, the cost is lowered, a contact area between the tooth bars and the tooth substrate is increased, the binding force is improved and the service life of the dipper tooth is prolonged.
Owner:CHINA UNIV OF GEOSCIENCES (BEIJING)

Five-patch type optical imaging lens and electronic device using same

The invention relates to an optical imaging lens. The optical imaging lens comprises a first lens, a second lens, a third lens, a fourth lens and a fifth lens in sequence from an object side to an image side. The first lens is a lens with a positive refractive index. The second lens is a lens with a negative refractive index. The object side face is provided with a concave face portion located in an area close to an optical axis. The image side face is provided with a concave face portion located in an area close to the optical axis. The object side face of the third lens is provided with a concave face portion located in the area close to the circumference. The image side face of the fourth lens is provided with a convex face portion located in the area close to the optical axis. The object side face of the fifth lens is provided with a concave face portion located in an area close to the optical axis. A portable electronic device comprises a machine shell and an image module arranged in the machine shell, and the image module comprises the optical imaging lens, a lens cone, a module base unit and an image sensor. The optical imaging lens and the electronic device can enable the lens to still have good optical performance under the condition that the length of the lens is reduced.
Owner:GENIUS ELECTRONICS OPTICAL XIAMEN

Special seaweed foliar fertilizer for tea trees and preparation method of seaweed foliar fertilizer

The invention relates to a special seaweed foliar fertilizer for tea trees. The special seaweed foliar fertilizer is prepared from the following ingredients in percentage by mass: 21-28% of seaweed extract, 10-15% of major element fertilizers, 5-10% of medium / trace element fertilizers, 0.5-1% of rare-earth element fertilizers, 20-45% of a chelating agent, 0.8-1.2% of a surfactant and the balance of water. The foliar fertilizer is prepared through weighing the metallic medium / trace element fertilizers and the chelating agent according to a formula ratio, respectively adding the metallic medium / trace element fertilizers and the chelating agent into water for dissolving, mixing, carrying out chelating reaction, adding the other ingredients, and uniformly stirring. The foliar fertilizer is low in cost and simple in production processing process and is safe and environmentally friendly; while the fertilizer effect is improved, the growth and development of crops can be promoted, the resistance is enhanced, the disease resistance of the crops is improved, and the quality of the crops is greatly improved.
Owner:SOUTH ASIAN TROPICAL AGRI SCI RES INST OF GUANGXI

Method for increasing content of mogroside IV

The invention discloses a method for increasing the content of mogroside IV. The method comprises the following steps: I, preparing a solid culture medium containing jasmonic acid methyl ester, wherein the concentration of the jasmonic acid methyl ester is 50-400 [mu] mol / L before the solid culture medium is cured; and II, inoculating momordica grosvenoritissue culture seedlings into the solid culture medium, culturing for 28-35 days, and transplanting the momordica grosvenori culture seedlings into fields. The method has the characteristics of being rapid in effect taking, low in cost, simple to operate, convenient to implement, free of toxin or reside in products, and the like, and by adopting the method, the yield of the mogroside IV can be effectively increased, and large-scale production of the mogroside IV can be achieved.
Owner:GUANGXI BOTANICAL GARDEN OF MEDICINAL PLANTS

Enzyme preparation and application thereof

The invention discloses an enzyme preparation. The enzyme preparation is characterized in that: one liter of the enzyme preparation comprises 0.5 to 20g of cotton seed hull removal enzyme, 0.2 to 20g of amylase, 0.5 to 10g of cellulose, and 1 to 100g of complex enzyme preparation of emulsifiable penetrant, wherein the pH of the complex enzyme preparation is 4 to 7. By applying the enzyme preparation, the conventional desizing and scouring process can be replaced. The defects of complex steps, high steam consumption, and electric power and sewage discharge value in the conventional fabric pretreatment processing are overcome, the damage to the fabric is reduced, the processing difficulty of pretreatment on cotton blend fabric and mixed fabric is reduced, and energy consumption, sewage and the chemical oxygen demand (COD) content in the sewage can be reduced.
Owner:HUZHOU MEIXINDA BIOLOGICAL TECH

Imaging lens system, image capturing unit and electronic device

ActiveCN109425968AContributes to light gathering abilityShorter overall optical lengthOptical elementsOptical axisImaging lens
The present invention discloses an imaging lens system. The imaging lens system includes, in order from an object side to an image side: a first lens element, a second lens element, a third lens element, a fourth lens element, a fifth lens element and a sixth lens element. The first lens element with negative refractive power has an image-side surface being concave in a paraxial region thereof. The second lens element with negative refractive power has an object-side surface being concave in a paraxial region thereof. The third lens element with positive refractive power has an image-side surface being convex in a paraxial region thereof. The fourth lens element has positive refractive power. The fifth lens element with negative refractive power has an image-side surface being concave in aparaxial region thereof. The sixth lens element with positive refractive power has an object-side surface being convex in a paraxial region thereof.
Owner:LARGAN PRECISION

Fractured stratum high-elasticity high-temperature-resistance plugging agent for drilling fluid and preparation method of plugging agent

InactiveCN109796943AIncrease elasticityHigh temperature resistance plugging agentDrilling compositionFiberWell drilling
The invention relates to the technical field of petroleum drilling materials, in particular to a fractured stratum high-elasticity high-temperature-resistance plugging agent for drilling fluid and a preparation method of the plugging agent. The fractured stratum high-elasticity high-temperature-resistance plugging agent for the drilling fluid is composed of sponge fibers, filled particles, a nano-micron lubricant and a viscosity regulator. An elastic material is adopted as a framework material, and easily enters cracks, and bridges are formed in the cracks, the plugging agent is made of a high-temperature resistant material, the success rate of plugging can be effectively improved, and repeated leakage is avoided. The plugging agent has good retention property, especially for large cracksand cave leakage, effective plugging can be formed at the position of a leakage layer, meanwhile, it can also be ensured that the plugging agent has good fluidity in the drilling fluid, and downhole complications due to poor rheology are prevented.
Owner:青岛海石元创石油技术有限公司

Apparatus and method for depositing synthetic fibers to form a non-woven web

The invention relates to an apparatus and a method for depositing synthetic fibers to form a non-woven web, in which method the synthetic fibers are guided in the form of a blowing stream through a drawing unit for being deposited on a deposit belt. For this purpose, inside the guidance distance between a blast opening of the drawing unit and the deposit belt, several guidance means are arranged, which form a guidance channel above the deposit belt, wherein the guidance means form a channel opening of the guidance channel at a distance from the blast opening of the drawing unit. In order to achieve constant strength in the deposition of the fiber strands in the non- woven web, the distance between the outlet of the drawing unit and the channel opening of the guidance channel is larger than half the guidance distance according to the invention, wherein the guidance width of an open space formed between the outlet of the drawing unit and the channel opening of the guidance channel is larger than that of the guidance channel.
Owner:OERLIKON TEXTILE GMBH & CO KG

Bionic phase change energy storage steam cavity module

The invention relates to a bionic phase change energy storage steam cavity module which comprises a tree-shaped steam cavity and a phase change container. The tree-shaped steam cavity comprises at least one steam cavity flat plate, a columnar steam cavity and multiple groups of branch and trunk steam cavity structures. One surface of the steam cavity flat plate is in contact with a heat source so that heat concentrated by the heat source can be uniformly diffused to the surface of the steam cavity flat plate, and the other surface of the steam cavity flat plate is packaged with the outer surface of the phase change container. The columnar steam cavity is connected with the steam cavity flat plate, and the multiple groups of branch and trunk steam cavities are arranged around the columnar steam cavity and each provided with two or more branch and trunk steam cavity branches extending towards the space. The multiple groups of branch and trunk steam cavities are connected through multiple layers of annular steam cavity ribs. Internal channels of the steam cavity flat plate, the columnar steam cavity, the branch and trunk steam cavities and the annular steam cavity ribs are communicated with one another, the internal spaces are filled with phase change working media, and the inner surfaces are provided with porous capillary structures. The tree-shaped steam cavity structure is arranged in the phase change container, and other parts in the phase change container are filled with phase change materials.
Owner:XI AN JIAOTONG UNIV

High-precision intelligent turbidity detecting device and calibration and using method thereof

The invention discloses a high-precision intelligent turbidity detecting device and a calibration and using method thereof. The device is divided into three layers, the probe structure of the bottom layer comprises a photodiode and two light emitting diodes on the same horizontal surface, one of the two light emitting diodes directly faces the photodiode and the other is perpendicular to the photodiode; the top layer is a circuit board comprising a constant current source driving circuit and a range switching circuit electrically connected to the constant current source driving circuit, and the range switching circuit is electrically connected to the two light emitting diodes in the bottom probe structure respectively. The high-precision intelligent turbidity detecting device disclosed bythe invention combines two measuring methods of 90-degree scattering method and transmission method, has high measuring precision and wide measuring range, and can be used in various measuring occasions. The cost-effective device having low cost and strong practicability is selected to obtain good application prospect and promotion value in the field of water quality detection.
Owner:OCEAN UNIV OF CHINA +1

Push-and-pull and side-hung door and window hardware system and use method thereof

The invention discloses a push-and-pull and side-hung door and window hardware system. A first lock point for locking a push-and-pull door and window sash in a door and window frame is arranged on the push-and-pull door and window sash. The other side of a side-hung door and window sash is provided with a second lock point for locking the side-hung door and window sash into the door and window frame. The push-and-pull door and window sash and the side-hung door and window sash are provided with the first lock point and the second lock point respectively, the first lock point achieves the antitheft effect and the limiting effect on the side-hung door and window sash, and the second lock point achieves the limiting effect and can be further matched with an anti-misoperation device to achieve the anti-misoperation effect. The push-and-pull door and window sash and the side-hung door and window sash of a push-and-pull side-hung door and window sash can switch off locking connection through a third lock point, the push-and-pull door and window sash is pushed to a proper position wherein the push-and-pull door and window sash and the side-hung door and window sash are overlapped, the push-and-pull door and window sash and the side-hung door and window sash can form a tight integrated structure, and combined linkage of the push-and-pull door and window sash and the side-hung door and window sash is facilitated.
Owner:佛山凯森贝格建筑五金有限公司

Supersaturated self-microemulsified administration system for insoluble anti-tumor drugs, and preparation method thereof

The invention belongs to the field of pharmaceutical preparation, and relates to a supersaturated self-microemulsified administration system for insoluble anticancer drugs, prepared from insoluble anti-tumor drugs, an emulsifier, a co-emulsifier, an oil phase and a crystallization inhibitor in different mass percents; and the administration system can be filled into soft capsules or hard capsules. The supersaturated self-microemulsified administration system is dispersible after oral administration to form microemulsion with the particle size of 10-100nm, thus inhibiting crystallization and separation of drugs, promoting absorption of drugs and improving the bioavailability of drugs. The administration system has the advantages of improving the solubility of the insoluble anticancer drugs in water, inhibiting the exocytosis of the intestinal epithelial cell p-glycoprotein on drugs, improving the bioavailability of drugs, eliminating the influence of foods on the absorption and bioavailability of drugs, and the like.
Owner:FUDAN UNIV

Original cream cheese and preparation method thereof

The invention discloses original cream cheese and a preparation method thereof. The original cream cheese is prepared from the following raw materials in percentage by mass of 35-55% of Greek yoghourt, 2-22% of butter, 1-8% of milk protein powder, 10-20% of coffee cream, 0.3-0.8% of table salt and 0.1-0.7% of a stabilizing agent, wherein the Greek yoghourt is fermented milk is prepared through thesteps of fermenting raw fresh milk and filtering off whey, the protein content of the Greek yoghourt is 6-12%, the fat content is 0-8%, and the pH value of the Greek yoghourt is 4.1-4.9. Compared with natural cream, the original cream cheese disclosed by the invention has the advantages that the production technology is simplified, the production cycle is shortened, in the production course, adjusting acidity and complementing water are not needed, the original cream cheese has great advantages in cost, and the nationalisation production of the product namely the original cream cheese can beaccelerated; and besides, the original cream cheese disclosed by the invention has rich milk fragrance, is smooth and fine in texture and free from granules, and can meet the quality demands of imported natural cream cheese.
Owner:BRIGHT DAIRY & FOOD

Smog sensor

The invention provides a smog sensor, which belongs to the technical field of coal mining safety facilities. The smog sensor comprises a smoke gathering hood, a smoke sensing probe seat, a smoke sensing probe, a circuit board, a soaring housing with a soaring cavity and a power supply and signal line interface unit, wherein a smoke sensing probe seat matching chamber is formed in the central part of the smoke gathering hood, a smoke gathering drum extends out from one side of the smoke gathering hood, the sidewall of the smoke gathering drum is provided with a set of lateral smoke inlet holes, the bottom of the smoke gathering drum is provided with a set of vertical smoke inlet holes, the smoke sensing probe seat cooperates with the smoke sensing probe seat matching chamber, a smoke sensing probe matching hole is provided at the center of the smoke sensing probe seat and is communicated with the smoke gathering drum, the smoke sensing probe is accommodated in the smoke sensing probe matching hole and is connected with the circuit board, the soaring housing is fixed with the smoke gathering hood and shields the smoke sensing probe seat, the smoke sensing probe and the circuit board, a suspension hook is fixed on a top wall of the soaring housing and the power supply and signal line interface unit is arranged on the top wall of the soaring housing. The smog sensor provided by the invention has the following advantages: the smoke sensing probe is allowed to sense smog in time; and installation of the smog sensor is convenient.
Owner:常熟市德虞矿山机电有限公司

River eel temporary rearing equipment with airbag gas filling and space compression

The invention relates to the technical field of aquaculture, and discloses river eel temporary rearing equipment with airbag gas filling and space compression. The river eel temporary rearing equipment with airbag gas filling and space compression comprises a water tank. The outer sleeve of the water tank is sleeved with a limited position frame, and the four corners of the lower surface of the limit frame are welded with legs. The outer side of the fixing frame is welded between the four legs, and the upper surface of the fixing frame is in contact with the lower surface of the water tank. The right side wall of the water tank is fixedly connected with the water outlet end of the drain pipe, and the inner wall of the drain pipe and the drain end are adhered with an escape net. The river eel temporary rearing equipment with airbag gas filling and space compression makes use of the setting of the pneumatic mechanism, the position of the movable plate in the water tank controlled by charging and discharging gas, and makes use of the shrinkage of the discharge hose to adapt to the shape of the river eel and grab the river eel through the discharge tube for easily catching the river eel in the tank.
Owner:刘树发

Integrated cooker for kitchen

The invention discloses an integrated cooker for a kitchen. The integrated cooker comprises a kitchen counter and an oil fume discharge device, wherein the oil fume discharge device is arranged in the kitchen counter; the kitchen counter comprises a kitchen counter face plate and a cabinet frame; a kitchen counter bottom plate is arranged in the cabinet frame; a wind shield device and a gas device are arranged between the kitchen counter face plate and the kitchen counter bottom plate; the wind shield device comprises a wind shield upper bracket and a wind shield lower bracket; a lifting device is arranged between the wind shield upper bracket and the wind shield lower bracket; the lifting device comprises a lifting screw rod; the lifting screw rod is connected with a driving device by a gear; the oil fume discharge device comprises a smoke inlet chamber and a cyclone chamber; the cyclone chamber comprises a fireproof chamber and a smoke discharge chamber; a fan is arranged at the lower end of the smoke discharge chamber; the fan is connected with a smoke discharge pipe. The oil strain enters an oil collection tank through an oil collection pipe by the fireproof chamber, thus being smoothly treated. The flue gas is discharged out of the integrated cooker through the smoke discharge pipe by the fan and enters an oil fume pipeline, thus being smoothly treated; therefore, the effect of separately treating the oil and the smoke can be achieved.
Owner:绍兴吾家电器有限公司

Flytrap

The invention discloses a flytrap and belongs to the field of articles for daily use. A liquid storage tank is provided herein; a suction pump is controlled to start through a control switch; a trapping liquid in the liquid storage tank is pumped into a liquid incoming pipe; the trapping liquid flows out of a liquid flow port of a functional liquid discharger; flies are attracted by the trapping liquid that is viscous; the trapping liquid sticks the flies and flows into a fly collection net in the liquid storage tank; the trapping liquid is cyclically utilized; after the flies are fully collected, the fly collection net is removed via a moving fastener such that the fly collection net can be removed and washed; the dead flies cannot affect normal operation of the flytrap; honey and fish meal are added to attract flies via fishy smell and sweet; a detergent can be added to help killing eggs of flies; generated froth helps allow flies to enter the trapping liquid; the efficient trappingliquid is attained by dispersing. Trapping efficiency is improved. The problem is solved that an existing flytrap may be stuck by dead flies inside and cannot operate continuously.
Owner:刘滨

Preparation method of core-shell structure loaded catalyst

The invention discloses a preparation method of a core-shell structure loaded catalyst. The preparation method of the core-shell structure loaded catalyst includes the steps of: first, preparation ofiron oxide hollow spheres; second, preparation of the active component Cu-Ni / Fe2O3 core-shell structure; third, hydrothermal synthesis of a ZSM-5 molecular sieve; and fourth, preparation of the core-shell structure loaded catalyst. According to the invention, when the core-shell structure is attached to the molecular sieve surface, the lattice defect in the molecular sieve and the stirring effectguide the embedding of the core-shell structure into the internal framework of the molecular sieve, and then by means of the hydrolytic precipitation of sodium bicarbonate, a uniform gel can be obtained. And the principle of high temperature roasting at 500-600DEG C lies in that: the intramolecular binding force increases gradually under the circumstance of high temperature, and the internal framework of ZSM-5 molecular sieve can shrink to a certain extent, under the shrinkage state, the prepared catalyst is more stable, and is not easy to inactivate in the reaction process, thus providing thereaction better catalytic activity.
Owner:HEFEI GUANGJUCAI BUILDING DECORATION ENG CO LTD

Antitumor slow-release implantation agent and preparation method thereof

The present invention belongs to the field of biomedicine, and particularly relates to an antitumor slow-release implantation agent, which comprises 10-hydroxycamptothecin, a degradable polymer and metal magnesium, and is obtained by a solution spraying or hot-melting extrusion process. According to the present invention, after the implantation agent is subjected to the surgical implantation, the slow release of the10-hydroxycamptothecin can be achieved, and compared with the traditional administration mode, the administration mode of the present invention has the following characteristics that the drug systemic toxicity can be substantially reduced in the premise of the effective maintenance of the local drug concentration of the tumor; the metal magnesium in the implantation agent can react with water in the body environment to generate magnesium hydroxide, such that the environment around the tumor can be adjusted to achieve the alkaline state so as to inhibit the tumor cell growth; and the implantation agent can be used alone or can be combined with other treatment methods to provide the treatment or tumor recurrence prevention effect.
Owner:THE FIRST HOSPITAL OF CHINA MEDICIAL UNIV +2

Efficient groundwater remediation system and method

The invention provides an efficient groundwater remediation system. The efficient groundwater remediation system comprises an intercepting ditch, a water collecting well, a sewage treatment system and a water purification tower, wherein the intercepting ditch is arranged at the downstream of a groundwater pollution area and used for intercepting groundwater in the groundwater pollution area; the water collecting well is arranged in the intercepting ditch and is used for collecting the groundwater intercepted by the intercepting ditch; the sewage treatment system is used for treating the groundwater in the water collecting well; the water purification tower comprises a vertically arranged third pipeline, the lower end of the third pipeline is buried underground and arranged at the upstream of the groundwater pollution area, and the groundwater treated by the sewage treatment system returns to the underground through the water purification tower. According to the efficient groundwater remediation system, the groundwater in an groundwater polluted area can be efficiently repaired.
Owner:SOUTH CHINA INST OF ENVIRONMENTAL SCI MEP

Sandy riverbed sediment pore water collecting device and manufacturing method thereof

The invention discloses a sandy riverbed sediment pore water collection device and a manufacturing method thereof, and aims to solve the problems of low success rate of riverbed sediment pore water collection, large external disturbance and high cost at present. According to the device, an upper steel pipe, a middle steel pipe, a lower steel pipe, a water inlet section and a bottom steel pipe aresequentially arranged from top to bottom, a solid stress steel ball is arranged at the top end of the upper steel pipe, a conical drill bit is arranged at the lower end of the bottom steel pipe, and two sampling holes are symmetrically formed in the pipe wall of the upper steel pipe relative to the axis; and a plurality of outer steel pipe water inlet holes are formed in the pipe wall of the outersteel pipe of the water inlet section, a plurality of inner steel pipe water inlet holes are formed in the pipe wall of the inner steel pipe, an outer steel pipe filter screen is arranged on the inner wall of the outer steel pipe, an inner steel pipe filter screen is arranged on the outer wall of the inner steel pipe, and a cavity between the inner steel pipe and the outer steel pipe is filled with quartz sand. The method comprises the following steps: 1, preparing device materials; 2, assembling; and 3, carrying out laser marking of scales. The device is used for collecting the sandy riverbed sediment pore water.
Owner:NORTHEAST INST OF GEOGRAPHY & AGRIECOLOGY C A S

Dual-pH sensitive drug carrier system and preparation method thereof

The invention discloses a dual-pH sensitive drug carrier system which is prepared by the following steps of modifying the surface of H-MnO2 encapsulating adriamycin (DOX) as an anticancer drug with a"valve" chitosan (CHI) to block a pore channel; and then, binding benzaldehyde terminated polyethylene glycol (mPEG-CHO) to CHI through an imine bond to prepare DOX@H-MnO2-CHI-PEG as the dual-pH sensitive drug carrier system. For the drug carrier system, under the protection of mPEG, the carrier can be "invisible" under the normal physiological conditios (with a pH value being 7.4), so that non-specific phagocytosis of normal cells can be avoided, and circulation time of the carrier in vivo can be prolonged; while in a tumor tissue less-acidic environment (with the pH value being 6.5), the imine bond binding the mPEG to the CHI is hydrolytically cleaved, the mPEG as a protective layer falls off, and the positively charged CHI is exposed, so that acid activation is realized, uptake of tumorcells to the carrier is promoted, and the situation that the carrier enters cancer cells is facilitated; and under a more acid environment (with the pH value being 5.5) in the cancer cells, H-MnO2 can further degrade, so that the DOX is released to kill the cancer cells.
Owner:HUBEI UNIV

Target magnetic nickel nano-medicinal preparation for inhibiting tumor cell growth and its production

A magnetic nano-Ni medicine with high target performance for suppressing the cells of tumor, especially the malignant tumor, is prepared through preparing the solution of the single-dispersing Ni nanoparticles with functionalized surface, ultrasonic stirring, adding it in the solution of quercetin or other medicine able to suppress the cells of tumor, and slight stirring.
Owner:SOUTHEAST UNIV

Manufacturing method of lead-free preserved eggs

The invention discloses a manufacturing method of lead-free preserved eggs and belongs to the technical field of poultry egg processing. The manufacturing method comprises the following steps: step 1, preparing preservation liquid: (1) preparing the preservation liquid from the following raw materials in parts by weight: 100 to 120 parts of a saturated sodium carbonate water solution, 10 to 20 parts of orchid flower and 20 to 30 parts of dried sea grass; (2) pouring the orchid flowers and the dried sea grass into the saturated sodium carbonate water solution and heating to 50 DEG C to 60 DEG C; keeping the temperature for 20min to 30min and filtering impurities to prepare a mixed solution; (3) after cooling the mixed solution to 15 DEG C to 20 DEG C, adding calcium hydroxide into the mixed solution until the calcium hydroxide and sodium carbonate completely react to prepare the preservation liquid; step 2, putting complete poultry eggs, which are washed, into the preservation liquid and preserving for 15 days to 20 days; keeping the preservation liquid completely immersing the poultry eggs in a preserving process; step 3, injecting carbon dioxide to the bottom of the preservation liquid at a ratio of adding 2g of the carbon dioxide into one liter of the preservation liquid, and sealing and preserving for 20 days to 25 days; step 4, covering mud on the preserved eggs. According to the manufacturing method provided by the invention, the preservation liquid and a preservation method of the preserved eggs are changed, so that the processed preserved eggs have a unique flavor and are good for health.
Owner:正安珍州仡佬食品有限公司

Wetting agent as well as preparation method and application of wetting agent

The invention belongs to the technical field of textile auxiliary agents and discloses a wetting agent as well as a preparation method and application of the wetting agent. The wetting agent is prepared from the following components in parts by weight: 1 to 1.2 parts of trans-4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol, 3 to 5 parts of citric acid triamine, 0.1 to 0.5 part of methyl orange, 12 to 14 parts of sodium sulfate, 0.5 to 0.7 part of zinc nitride, 3 to 4 parts of sodium dimethylbenzenesulfonate, 0.6 to 0.9 part of methylisothiazolinone, 100 to 120 parts of polyethylene glycol and 300 to 350 parts of de-ionized water. The invention also discloses the preparation method of the wetting agent. The wetting agent disclosed by the invention can be widely applied to a plurality of processes of sizing, bleaching, desizing, refining, dyeing, after-finishing textiles and the like, can be used for mercerization treatment on pure cotton textiles and carbonization treatment on wool textiles, and has a wide application prospect.
Owner:FOSHAN XUNTUOAO TECH CO LTD

Culture net cage capable of automatically supplying oxygen and changing water

The invention belongs to the technical field of net cage culture, and relates to a culture net cage capable of automatically supplying oxygen and changing water. The device comprises a culture net cage, wherein the culture net cage comprises an upper supporting floating frame and a lower supporting frame, a plurality of bait recovery cylinders are arranged between the upper supporting floating frame and the lower supporting frame, and an anchor is connected to each bait recovery cylinder through a rod; upper pistons are arranged in the bait recovery cylinders; piston rods are coaxially fixed to the upper pistons, the upper ends of the piston rods extend out of the bait recovery cylinders and the end parts are connected with the upper supporting floating frame; an air inlet pipe is arrangedon one of the bait recovery cylinder and air exhaust pipes are arranged on the bait recovery cylinders; one end of the air inlet pipe and one end of the air exhaust pipes both extend into a chamber partitioned by each the upper piston into each the bait recovery cylinder; the other end of the air inlet pipe extends out of the sea surface and an air inlet one-way valve is fixed to the end part; and the other end of each the exhaust pipe extends into the culture net cage and an air exhaust one-way valve is arranged at each the end part. The device has the advantages of realizing automatic oxygen supply and water exchange of the culture net cage.
Owner:ZHEJIANG OCEAN UNIV

Integrated preparation method for straw fodder

The invention discloses an integrated preparation method for straw fodder. The integrated preparation method comprises the following steps: cutting straws into pieces, and spreading to obtain a firststraw bed; weighing glucoamylase, hemicellulase and cellulase, preparing into first mixed liquid of which the mass fraction is 10%, spraying the first mixed liquid on the first straw bed to obtain a second straw bed; weighing urea, ammonium bicarbonate, ammonium carbonate and ammonium chloride to prepare second mixed liquid of which the mass fraction is 20%, spraying the second mixed liquid on thesecond straw bed, carrying out sealing processing for 7 days, drying, and smashing into straw powder; mixing the straw powder and third mixing liquid, standing under the environment of -5 DEG C for 12h, taking out to be unfrozen, carrying out microwave radiation and rotary evaporation and concentration, and drying to obtain modified straw powder; adding a fodder additive into the modified straw powder to prepare the straw fodder. According to the integrated preparation method, the palatability of the straw fodder can be improved, the nutrition value of the straw fodder is improved, and meanwhile, the straw fodder can be more easily digested by livestock.
Owner:康桥投资控股有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products