190results about How to "Diffusion slow" patented technology

The invention relates to a biodegradable implant or the like manufactured of polymer-based material and intended to be installed in tissue conditions. In the macroscopic structure of the implant two or several zones are created in a manner that the biodegradable polymer-based material has in different zones a different detaching time from the macroscopic structure under tissue conditions.

An integrated circuit and method of fabricating the integrated circuit is disclosed. The integrated circuit includes vertical bipolar transistors (30, 50, 60), each having a buried collector region (26′). A carbon-bearing diffusion barrier (28c) is disposed over the buried collector region (26′), to inhibit the diffusion of dopant from the buried collector region (26′) into the overlying epitaxial layer (28). The diffusion barrier (28c) may be formed by incorporating a carbon source into the epitaxial formation of the overlying layer (28), or by ion implantation. In the case of ion implantation of carbon or SiGeC, masks (52, 62) may be used to define the locations of the buried collector regions (26′) that are to receive the carbon; for example, portions underlying eventual collector contacts (33, 44c) may be masked from the carbon implant so that dopant from the buried collector region (26′) can diffuse upward to meet the contact (33). MOS transistors (70, 80) including the diffusion barrier (28) are also disclosed.

Semiconductor devices and methods for fabricating semiconductor devices are provided. One exemplary method comprises providing a silicon-comprising substrate having a first surface, etching a recess into the first surface, the recess having a side surface and a bottom surface, implanting carbon ions into the side surface and the bottom surface, and forming an impurity-doped, silicon-comprising region overlying the side surface and the bottom surface.

Methods for preparing a series of mesoporous silicates, such as room-temperature ionic liquid (RTIL)-templated mesoporous silicate particles, with various particle morphologies are provided. Methods for preparing silicate particles with antimicrobial agents within the MSN pores is also provided. The particles can be used as controlled-release nanodevices to deliver antimicrobial agents.

Provided is a technique for fabrication of a nitrided gate oxide and shallow trench isolation (STI) oxide liner in a semiconductor depletion into STI oxide and the RNCE in CMOS devices by introducing nitrogen to the STI edges of the p-well. This technique improves isolation performance and is also effective to harden the oxide to reduce boron penetration. Nitridization of the STI liner may be conducted on its own or in combination with gate oxide nitridization, both with beneficial effect with regard to the RNCE. The nitridization may also be focussed on the channel region of the gate oxide in particular in order to mitigate RSCE.

A method for determining a concentration of an analyte is disclosed. The method includes applying a potential excitation to a fluid sample containing an analyte and determining if a current decay curve associated with the fluid sample has entered an analyte depletion stage. The method also includes measuring a plurality of current values associated with the fluid sample during the analyte depletion stage and calculating an analyte concentration based on at least one of the plurality of current values.

A membrane is provided including a coating layer having cellulose nanofibers produced from oxidized cellulose microfibers and an electrospun substrate upon which the coating layer is applied. The nanofibers of the electrospun substrate have a diameter greater than that of the cellulose nanofibers. The membrane also has non-woven support upon which the electrospun substrate is disposed. Microfibers of the non-woven support have a diameter greater than that of the nanofibers of the electrospun substrate. Application of electrospun membrane is in microfiltration area, while the cellulose nanofiber membrane serves in ultra-filtration, nanofiltration, and reverse osmosis after chemical modification.

Biodegradable neurotoxin implants and methods of making and using such implants are provided. Biodegradable neurotoxin implants include a neurotoxin, a biodegradable polymer component, and an acidity regulating component. The biodegradable polymer component is effective in controlling the release of the neurotoxin from the implant when the implant is located in a patient's body. The acidity regulating component is effective in maintaining a pH of the implant in a desired range that may be effective in stabilizing the neurotoxin as the implant biodegrades when the implant is located in a patient's body. In one embodiment, an implant includes a botulinum toxin, a biodegradable polymer, and either monomers from which a biodegradable polymer is derived or oligomers including monomeric units substantially identical to a monomer from which a biodegradable polymer is derived, or a combination of such monomers and oligomers. The oligomers and biodegradable polymer may be derived from a single type of monomer. The implants disclosed herein may be administered to a human or animal patient in which a therapeutic effect is desired for prolonged periods of time.

Controlled release oral dosage forms are provided for the continuous, sustained administration of a pharmacologically active agent to the upper gastrointestinal tract of a patient in whom the fed mode as been induced. The majority of the agent is delivered, on an extended release basis, to the stomach, duodenum and upper regions of the small intestine, with drug delivery in the lower gastrointestinal tract and colon substantially restricted. The dosage form comprises a matrix of a biocompatible, hydrophilic, erodible polymer with an active agent incorporated therein, wherein the polymer is one that both swells in the presence of water and gradually erodes over a time period of hours, with swelling and erosion commencing upon contact with gastric fluid, and drug release rate primarily controlled by erosion rate.

Photoacid generator salts comprising photoactive cationic moieties and segmented, highly fluorinated-hydrocarbon anionic moieties are disclosed which provide high photoacid strength and can be tailored for solubility and polarity. The present invention further relates to photoacid generators as they are used in photoinitiated acid-catalyzed processes for uses such as photoresists for microlithography and photopolymerization.

A method of fabricating an array of biopolymers provides a shield for biochemical reactions and biochemical reactants and is particularly useful for those reactions and reactants that are susceptible to reaction with a component of the ambient environment during the fabrication of the array. The method is applicable to the conventional fabrication and synthesis methods used to fabricate a biopolymer array, such as in situ synthesis of biopolymers on an array and the attachment of pre-synthesized biopolymers on to an array. The method comprises applying a non-miscible fluid (NMF) to the array surface where the biopolymers are being synthesized or attached. The NMF is inert and insoluble with the biochemical reactants and other ancillary materials in solution used in conventional synthesis or attachment of biopolymers. The NMF provides a shield between the ambient atmosphere and the biopolymer synthesis materials or the deprotected pre-synthesized biopolymer at the surface of the array during the synthesis or attachment processes. The NMF may be applied as droplets over each feature location on the surface or may be applied by flooding the surface of the array to fully cover the features. Biomonomer or biopolymer solutions are deposited into or through the NMF to the feature locations on the surface of the array where the synthesis or attachment reactions are to take place using conventional deposition equipment to eject the solutions into the NMF. The NMF provides a shield for activated biomonomers that are susceptible to reaction with a component in the ambient environment, such as moisture in the air. Moreover, the NMF provides a shield for pre-synthesized biopolymers that are susceptible to evaporation when deprotected for attachment to the array surface. The method provides a means by which the potential reactivity of the activated biomonomer or deprotected biopolymer with an ambient atmosphere component can be kept low. As a result, biopolymer arrays can be more accurately fabricated.

This invention is directed to a method of manufacturing a liquid agricultural fertilizer utilizing biosolids and high concentrations of nitrogen and other essential plant nutrients and the resulting products.

An acoustic ventilator using feedback control is designed to generate and exert a desired mixture of pressure oscillations into a supply of gas entering a subject's airways to maintain optimal ventilation and perfusion in the lungs. According to the subject's biological specifications and real-time medical condition, computers and human interface control the vibrations in intensity and frequency along with the pressure and composition of blended gases in order to enhance oxygenation and CO2 clearance. Acoustic ventilation will cause the ventilating gases to diffuse through the subject's lungs without the aid of a separate ventilator, and with or without spontaneous breathing.

The present invention aims at providing a method of manufacturing a semiconductor device capable of suppressing metal diffusion from the upper face of wiring.In the present invention, a copper seed film containing copper and a first metal element is formed in a groove formed in a first interlayer film over a semiconductor substrate. After that, a copper plating treatment is performed. After that, a first heat treatment is performed in a first atmosphere in which the copper layer is not oxidized. Then, an excess metal layer of copper alloy is removed and copper alloy wiring is formed in the groove. After that, a second heat treatment is performed in a second atmosphere containing oxygen to form an oxide layer being the oxide of the first metal element over the surface of the copper alloy wiring.

By using a non-conformal diffusion barrier in conjunction with a similarly deposited non-conformal initial deposition of siliciding material, a substantially uniform and conformal silicide can be formed in a 3D structure such as the fin of a FinFET. The siliciding material may be nickel (Ni), the diffusion barrier may be titanium (Ti) or titanium nitride (TiN). Generally, the diffusion barrier may be any material which will inhibit, but not block, diffusion of the siliciding material into the silicon. In this manner, a non-conformal barrier deposition, in conjunction with a non-conformal silicide material deposition, after anneal, results in substantially conformal silicide formation.

Devices for determining the concentration of a constituent in a physiological sample that comprise gel matrices to filter red blood cells are provided. Examples of such devices include a biosensor comprising, on a support substrate, a sample reception region for receiving a blood sample; at least one electrode; and a reaction reagent system that is located in a gel matrix. The gel matrix disclosed herein is sufficient to prevent at least some of the red cells in the blood sample from contacting the electrode, and thus reduce the hematocrit sensitivity in the measurement.

A semiconductor device having well-defined profiles is disclosed. A p-type pocket / halo region is preferably formed along a channel-side border of the heavily doped source / drain region to neutralize diffused n-type elements. A diffusion-retarding region is formed to retard diffusion for both p-type and n-type impurities by substantially overlapping or extending beyond the p-type pocket / halo region and the N+ S / D region at least on the channel side.

One embodiment of the invention provides a computer-implemented method of annotating images in a data set comprising a first set of images which initially have annotations and a second set of images which initially do not have annotations. The method comprises the steps of determining spatial correspondences for all pairs of images in the data set, wherein each spatial correspondence represents a mapping of a location in a first image to a corresponding location in a second image. For each mapping, the method further comprises calculating a connection strength between the location in the first image and the corresponding location in the second image. The method further comprises iteratively propagating information across images in the data set using the connection strengths of the mappings as weights for propagating the information, augmented by an estimate of propagation accuracy, wherein the propagated information is used to provide annotations to images which do not initially have annotations, and wherein each iteration performs a propagation across all images in the data set.

The present invention relates to bispecific antibody against human vascular endothelial growth factor (VEGF / VEGF-A) and against human angiopoietin-2 (ANG-2) of human IgG1 or IgG4 subclass with mutations I253A, H310A, and H435A, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.

The invention, which relates to the electronic device field, discloses a method and apparatus for manufacturing an insulated gate bipolar transistor (IGBT) device. According to the invention, forming of a field stop (FS) region and a collector at a back side of an IGBT device is not carried out after completion of a metal-oxide-semiconductor field effect transistor (MOSFET) manufacturing of the IGBT and back-side grinding but is carried out before, after and during the MOSFET manufacturing process in an interspersed mode. A thick FS is formed; after the forming of the FS with the needed thickness, devices like a front-side MOSFET are manufactured without influencing characteristics of devices that are manufactured afterwards and includes a MOSFET at a front side of a silicon ship. And the high temperature process of the manufacturing of the devices at the front-side of the silicon chip has little impact on the FS with the thickness of 20 to 30 micrometers. Ion implantation of P type impurities of the back-side collector is carried out after deposition of an oxide layer at the side wall of the front-side MOSFET and the activation of the P type impurities is carried out by the thermal process of the manufacturing of the front side MOSFET; and the activation rate is high and the damage caused by the ion implantation can be eliminated. Therefore, an IGBT with high breakdown voltage, low electricity leakage, conduction voltage drop positive temperature coefficient and low switching loss is manufactured.

An automobile or vehicle having a high efficiency solar control system is provided. The automobile may have a window defined by a sheet of glass and a film mounted to its exterior side. The film may reflect solar radiation in the near and mid infrared ranges yet allow high transmission of light in the visible range such that the occupants of the automobile may view his / her surroundings through the window. The film may have a layer of silver which reflects the solar radiation in the near and mid infrared ranges. Since the silver is susceptible to oxidation and turns the silver into a black body which absorbs the near and mid infrared radiation, the film may be designed to slow the rate of oxidation of the silver layer to an acceptable level. The silver layer may be sandwiched between the glass which does not allow oxygen to diffuse there through and reach the layer of silver and a stack of sacrificial layers having a certain thickness which slows down the rate of oxygen diffusion to an acceptable level.

The present invention relates to methods and compositions for treating a surface of a substrate by foam technology that includes at least one treatment chemical. The invention more particularly relates to the removal of undesired matter from the surface of substrates with small features, where such undesired matter may comprise organic and inorganic compounds such as particles, films from photoresist material, and traces of any other impurities such as metals deposited during planarization or etching. A method according to the present invention for treating a surface of a substrate comprises generating a foam from a liquid composition, wherein the liquid composition comprises a gas; a surfactant; and at least one component selected from the group consisting of a fluoride, a hydroxylamine, an amine and periodic acid; contacting the foam with the surface of a substrate; and, removing the undesired matter from the surface of the substrate.

Methods of producing a controlled release formulation for an active substance are disclosed, wherein the methods involve dispersing a discontinuous phase comprising an active substance into a continuous phase so as to form a two-phase liquid system comprising droplets of said discontinuous phase, and allowing nanoparticles provided to the two-phase liquid system to congregate at the phase interface to thereby coat the surface of the droplets in at least one layer of said nanoparticles. The methods utilise a concentration of a suitable electrolyte which enhances the nanoparticle congregation such that the coating of nanoparticles on the surface of the droplets presents a semi-permeable barrier to the active substance, or otherwise utilise a amount of the active substance that is greater than the solubility limit of that active substance in the discontinous phase. Formulations comprising vitamin A (retinol) as the active substance for dermal delivery are specifically exemplified.

A wiring structure with improved resistance to void formation and a method of making the same are described. The wiring structure has a first conducting layer that includes a large area portion which is connected to an end of a protrusion with a plurality of “n” overlapping segments and at least one bending portion. The other end of the protrusion is connected to the bottom of a via which has an overlying second conducting layer. A bend is formed by overlapping the ends of two adjacent segments at an angle between 45° and 135°. The protrusion may also include at least one extension at a segment end beyond a bend. A bending portion and extension are used as bottlenecks to delay the diffusion of a vacancy from the large area portion to the vicinity of the via and is especially effective for copper interconnects or in a via test structure.

Compositions, systems and methods for the controlled and / or delayed release of chemical additive components into an aqueous fluid used in hydraulic fracturing of oil and / or gas wells. The chemical additive components may include a viscosity-reducing composition, an oxidizer composition, a pH modulating composition, a lubricant composition, a cross-linking composition, an anti-corrosion composition, an biocide composition, a crosslink-enhancing composition, and / or a combination of two or more of these compositions. Further embodiments include additives and methods of delivering a particle comprising an additive component to a desired site in an aqueous medium prior to release of the additive component into the aqueous medium. The coating is permeable, but insoluble in an aqueous medium, whereupon the additive components are released into the medium.

A housing (410, 510, 610, 700, 800, 900) for a turbocharger (400, 500, 600) is provided. The housing (410, 510, 610, 700, 800, 900) has an impeller chamber (403, 503, 603), diffuser (450, 550, 650, 750, 850, 950) and scroll (420, 520, 620, 720, 820, 920) in fluid communication with each other. The diffuser (450, 550, 650, 750, 850, 950) can have a curved shape and / or a bend (455) in proximity to a tip (408, 508, 608, 609) of the impeller (405, 505, 605). The curved shape can be defined by one or more radii of curvature (RC, RC1, RC2). The diffuser (450, 550, 650, 750, 850, 950) can extend in a radial direction that is non-orthogonal to the center line of the turbocharger (400, 500, 600). The housing (410, 510, 610, 700, 800, 900) can be for a compressor section of the turbocharger (400, 500, 600).