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76results about How to "Minimizes variability" patented technology

Automated brain MRI and CT prescriptions in Talairach space

Brain Magnetic Resonance Imaging (MRI), Computerized Tomotography (CT), or other diagnostic modalities may employ a three-step procedure during initial (“scout”) cranial pre-scans that corrects for patient positioning (i.e., roll, yaw and pitch) to reduce inter- and intra-patient variation, thereby enhancing the diagnostic and comparative value of subsequent detail scans even across different diagnostic platforms. In MRI, for instance, locating the saggital sinus (SS) and optimizing a line to bisect the brain through this SS may be automated to correct for roll and yaw. By then identifying the contour of the corpus callosum in a lateral saggital scout scan, the Talairach anterior commissure (AC)—posterior commissure (PC) reference line may be found for correcting pitch. Prescription of detailed scans are improved, especially when the three-step correction is repeated periodically identifying the need to repeat a detailed scan or to adjust the coordinates of a subsequent scan.
Owner:ABSIST +1

Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract

Controlled release oral dosage forms are provided for the continuous, sustained administration of a pharmacologically active agent to the upper gastrointestinal tract of a patient in whom the fed mode as been induced. The majority of the agent is delivered, on an extended release basis, to the stomach, duodenum and upper regions of the small intestine, with drug delivery in the lower gastrointestinal tract and colon substantially restricted. The dosage form comprises a matrix of a biocompatible, hydrophilic, erodible polymer with an active agent incorporated therein, wherein the polymer is one that both swells in the presence of water and gradually erodes over a time period of hours, with swelling and erosion commencing upon contact with gastric fluid, and drug release rate primarily controlled by erosion rate.
Owner:DEPOMED SYST INC

Transdermal Delivery of Meptazinol

A delivery system for the delivery of a salt of meptazinol or meptazinol precursor which increases the bioavailability of meptanizol by an effective amount to provide analgesic relief is disclosed. One embodiment of the delivery system is a transdermal device which increases the skin flux of meptazinol by an effective amount to provide analgesic relief. Also disclosed are methods of providing analgesic relief.
Owner:SHIRE PHARMA INC

Light emitting device

To minimize the variability in the emitted light color and improve the unevenness of color tone, a light emitting device comprises a light emitting element and a fluorescent substance that is excited by the light emitting element, wherein the light emitting element has an emission spectrum in a region from ultraviolet to visible light of short wavelengths, and the fluorescent substance has an emission spectrum that includes two or more emission peaks with at least two peaks of the two or more peaks being in the relation of complementary colors of each other.
Owner:NICHIA CORP

Fluid flowing device and method for tissue diagnosis or therapy

A device and method for safely securing a multilumen device to a tissue, organ or solid tumor within the body of a human during a diagnostic or therapeutic procedure is described. The device is capable of securing the tumor by touching or piercing its surface and providing a coolant to the distal tip. Cooling the tip forms a cryogenically induced region that tightly binds the tip to the tumor, temporarily sealing the entry-track of the instrument. The device further provides at least one injecting / aspirating lumen that can dispense or aspirate a fluid within the tumor, and an outer sheath or guide. Such construction allows injecting part or whole volume of the tumor while the cryogenically induced bond prevents back-flow of the injected substances through the entry-track.
Owner:NUVUE THERAPEUTICS

Active noise reduction audiometric headphones

Active noise reduction headphones for audiometry where the earphone portion of said headphones has a cavity volume greater than 6 cc and including an acoustic-electric sensing means and an electro-acoustic transducing means which are used cooperatively and which has additional passive noise control means in the form of a circumaural seal around the ear for improving high frequency noise control performance, the headphone having a summing junction for combining the active noise reduction signal and an audiometry test signal.
Owner:GENTEX CORP

Disk drive enclosure

Noise is reduced in a disk drive enclosure by using vibration damping materials on the inside surface of the enclosure. These materials and their placement on the inside surface of the enclosure reduce noise without thermally insulating the disk drive. A temperature controlled fan may be used to remove heat by convection while generating a minimum amount of noise. The connection between the disk drive and the external connector of the disk drive enclosure is made more reliable by using a printed circuit board instead of a cable. Because a printed circuit board has a fixed location and fixed layout, variability among disk drive enclosures can be minimized. Also, errors in manufacturing of the disk drive enclosure can be reduced. To facilitate the use of the disk drive in a stripe set, the disk drive enclosure has a set of mechanical interlocks that permit the enclosures to be stacked vertically. In one embodiment, the mechanical interlocks are constructed in a manner that permits stacking in unlocked and locked configurations. The locked configuration may be made permanent using an additional locking mechanism. These mechanical interlocks also may be used to support the enclosure on a desktop. The mechanical interlocks also may be constructed so that they can slide on a rail, permitting the enclosure to be used in a rack mount. The rack mount also may be provided with a quick-release mechanism that interacts with the mechanical interlocks to hold the disk drive enclosure in the rack mount.
Owner:AVID TECHNOLOGY

Method and system for product optimization

A method and computer-implemented system for optimizing a product. Based on the "voice of the customer", aspects of the product that are critical to the customer satisfaction, and target values, therefore, are identified. Aspects are characterized in terms of their contributing factors. Each contributing factor is characterized in a transfer function in terms of control and noise factors impacting the contributing factors. Contributing factors are optimized during product design by shifting nominal design values for control factors with respect to the transfer function such that target contributing factors are attained with minimum variability due to existing noises and variability in control. Where target values cannot be obtained through design optimization, conventional methods of manufacturing optimization are implemented. The extent to which the target values are attained and maintained over the life of the product are assessed.
Owner:FORD MOTOR CO

Crash Attenuation System for Aircraft

A crash attenuation system for an aircraft, the system having an airbag carried by the aircraft and inflatable generally adjacent an exterior of the aircraft. The airbag has at least one vent for releasing gas from the interior of the airbag. A first gas source is in fluid communication with the interior of the airbag for inflating the airbag with gas generated provided by the first gas source. A vent valve is provided for controlling a flow of gas through each vent, each vent valve being selectively configurable between an open state, in which gas can pass through the associated vent from the interior of the airbag, and a closed state, in which gas is retained within the interior of the airbag. A second gas source is provided for at least partially re-inflating the airbag after venting of gas through the at least one vent.
Owner:TEXTRON INNOVATIONS

Crash attenuation system for aircraft

A crash attenuation system for an aircraft, the system having an airbag carried by the aircraft and inflatable generally adjacent an exterior of the aircraft. The airbag has at least one vent for releasing gas from the interior of the airbag. A first gas source is in fluid communication with the interior of the airbag for inflating the airbag with gas generated provided by the first gas source. A vent valve is provided for controlling a flow of gas through each vent, each vent valve being selectively configurable between an open state, in which gas can pass through the associated vent from the interior of the airbag, and a closed state, in which gas is retained within the interior of the airbag. A second gas source is provided for at least partially re-inflating the airbag after venting of gas through the at least one vent.
Owner:TEXTRON INNOVATIONS

Fluid flowing device and method for tissue diagnosis or therapy

ActiveUS20090036823A1Minimizing operator-associated variabilityBroaden applicationElectrotherapyMulti-lumen catheterInjected substanceSolid tumor
A device and method for safely securing a multilumen device to a tissue, organ or solid tumor within the body of a human during a diagnostic or therapeutic procedure is described. The device is capable of securing the tumor by touching or piercing its surface and providing a coolant to the distal tip. Cooling the tip forms a cryogenically induced region that tightly binds the tip to the tumor, temporarily sealing the entry-track of the instrument. The device further provides at least one injecting / aspirating lumen that can dispense or aspirate a fluid within the tumor. Such construction allows injecting part or whole volume of the tumor while the cryogenically induced bond prevents back-flow of the injected substances through the entry-track.
Owner:NUVUE THERAPEUTICS

Method and system for making extruded portions of cheese

InactiveUS20110014311A1Reduces and avoids heat distortionImprove production stabilityTailstocks/centresConfectioneryEngineering
A method and system are provided for portioning a cheese mass to be sliced and shredded directly from a quantity of bulk cheese, without the need to thermally process the cheese. The cheese extrudate strands and sheets are cut to provide discrete cheese shreds and slices, and can be automatically portioned and deposited in packages.
Owner:INTERCONTINENTAL GREAT BRANDS LLC

Light emitting device

To minimize the variability in the emitted light color and improve the unevenness of color tone, a light emitting device comprises a light emitting element and a fluorescent substance that is excited by the light emitting element, wherein the light emitting element has an emission spectrum in a region from ultraviolet to visible light of short wavelengths, and the fluorescent substance has an emission spectrum that includes two or more emission peaks with at least two peaks of the two or more peaks being in the relation of complementary colors of each other.
Owner:NICHIA CORP

Method for operating an imaging diagnostic device and medical imaging system

A method for operating an imaging diagnostic device is proposed. Raw data is generated by the diagnostic device as a function of modality parameters while utilizing a contrast medium that is used in accordance with an injection protocol. Image data is generated from the raw data by image reconstruction as a function of reconstruction parameters. A quantitative measurement is performed in an image data evaluation by an analysis application. A subsidiary application automatically proposes a set of parameter values which is suited to the analysis application and relates to the injection protocol utilizing stored comparison data.
Owner:SIEMENS AG

Spectroscopic analysis of oil sands ore face for real time ore blend management

Apparatus is provided featuring a signal processor or signal processing module configured to receive signaling containing information about images of an ore sample; and determine information about a Bitumen Content of the ore sample based at least partly on the signaling, including for use in real time ore blend management in a bitumen recovery process related to mined oil sands. The ore sample may be an ore face, and the signaling may contain information about the images of the ore face. The signal processor or signal processing module may be configured to determine a real time ore face ore grade visualization based at least partly on the signaling, and provide corresponding signaling containing information about the real time ore face ore grade visualization, including a composite overlay image.
Owner:CIDRA CORP SERVICES

Method and system for making extruded portions of cheese

A method and system are provided for portioning a cheese mass to be sliced and shredded directly from a quantity of bulk cheese, without the need to thermally process the cheese. The cheese extrudate strands and sheets are cut to provide discrete cheese shreds and slices, and can be automatically portioned and deposited in packages.
Owner:KRAFT FOODS GRP BRANDS LLC

Automotive body and trim assembly with complementary locating and positioning features and method of assembling same

An automotive body and trim assembly is provided that utilizes locating features on only a single sheet metal layer of a multi-layer body frame pillar to position a trim member, thus minimizing variability in the final assembled position of the trim member. The single sheet metal layer has both a fore-aft-locating feature and a cross-car-locating feature. A fore-aft-positioning feature and a cross-car-positioning feature on the pillar trim member are spaced to permit contact with the fore-aft-locating feature and the cross-car-locating feature, respectively when the pillar trim member is assembled with the body frame pillar, so that only the single sheet metal layer determines the fore-aft and cross-car position of the pillar trim member. A method of assembling a pillar trim member and a body frame pillar having multiple sheet metal layers is also provided.
Owner:GM GLOBAL TECH OPERATIONS LLC

Total harmonic distortion standard

Embodiments of the invention provide a method and an apparatus for generating a total harmonic distortion reference signal. A triangle wave having a predetermined frequency and a predetermined amplitude is generated. The triangle wave is filtered to produce a signal substantially consisting of a sinusoid at the predetermined frequency and selected harmonics of predetermined amplitudes.
Owner:THE BOEING CO
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