An ultrasonic cleaning device for large disc shaft parts of an aircraft engine comprises a main water draining opening, a stainless steel turbulence pump, a stainless steel filter, a pressure gage, a cleaning box water draining valve, a cleaning box, pneumatic control groove covers, an overflow water returning opening, a liquid storage groove, heat preservation layers, side ultrasonic vibration plates, stainless steel heating bars, a bottom ultrasonic vibration plate, a tool protection frame, a part tool frame, an ultrasonic vibration bar and a transverse ultrasonic vibration plate. The stainless steel turbulence pump is connected with the liquid storage groove through a thread pipelinr, the stainless steel filter is connected with the stainless steel turbulence pump through a pipeline, the cleaning box water draining valve is connected with the main water draining opening and the bottom of the cleaning box through a pipeline, and the side ultrasonic vibration plates, the transverse ultrasonic vibration plate and the bottom ultrasonic vibration plate are connected with a liquid storage groove inner cavity through bolts and copper gaskets. The ultrasonic cleaning device has the beneficial effects that oil contamination, carbon deposition and micrometer and submicron dirty marks on the inner surface and the outer surface of the large disc shaft parts can be completely removed, the operation process is simple, and the cleaning cost and the cleaning time are saved.