The invention provides a method for producing RHD (rabbit haemorrhagic disease) virus and vaccine by use of common easy-to-culture cell lines such as RK13, ST, VeroE6, BHK-21, PK-15, IBRS-2 and the like. The method comprises the following steps of: inoculating the RHD virus and adsorbing; adding an incubation agent and performing cell incubation; culturing cells with a cell maintenance medium to obtain RHD virus seeds for production; inoculating the RHD virus seeds and adsorbing; adding an incubation agent and performing cell incubation; re-adding a cell maintenance medium and culturing cells to obtain the RHD virus for vaccine preparation; adding an inactivator for inactivation; and then adding a veterinary-pharmaceutically acceptable vaccine adjuvant to obtain a finished product of the RHD vaccine. According to the method, the cell line for virus culture is a mature commercial cell line, the production technology is simple and stable, the operation is easy, the virus content is high, the inter-batch difference is little, the quality is easy to control, and the output and quality of the vaccine can be obviously improved. Through the invention, the produced RHD vaccine has high safety and high immunity, and realizes a complete immune protection effect against the RHD virulent attack.