The invention discloses an anti-fatigue compound preparation and a preparation method thereof, wherein the preparation comprises the following components in percentages by weight: 10-65% of
salvia miltiorrhiza, 15-35% of
astragalus, 15-35% of herba epimedii and 5-20% of Chinese wampee fruit. In the invention, the
salvia miltiorrhiza,
astragalus, herba epimedii and Chinese wampee fruit are adopted, which contain phenolic acids, flavonoids,
pectin, polysaccharides and
saponin compounds, have the functions of increasing coronary
blood flow, reducing blood lipid, inhibiting
thrombosis, improving
microcirculation, eliminating free radicals, preventing oxidization and the like, and can be used for preventing body fatigue and movement injuries, enhancing the body
immunity and protecting the organs and tissues from being damaged. A variety of nutrients in the present invention activate the immune systems at different levels and generate a comprehensive anti-fatigue effect, the
traditional Chinese medicine with an
immunity enhancement function is prepared into a novel compound preparation by means of modern extraction separation and preparation formation process, to improve the activity of the
drug.