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Active extract of citrus peels as well as extraction process and application thereof

An extraction process and a technology for citrus peel, which is applied in the field of extraction technology of effective components of citrus peel, can solve problems such as poor efficacy stability, and achieve the effects of good efficacy stability, improved vitality and reasonable process conditions

Active Publication Date: 2010-10-06
GUANGDONG PHARMA UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide an active extract of citrus peel with antioxidant effect according to the problems of limited practical application and poor efficacy stability in the existing research on active ingredients of citrus peel

Method used

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  • Active extract of citrus peels as well as extraction process and application thereof
  • Active extract of citrus peels as well as extraction process and application thereof
  • Active extract of citrus peels as well as extraction process and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 Extraction of citrus peel antioxidant activity extract

[0027] Dried citrus peel 5.26kg, crushed to 20 mesh, packed with 10cm × 12cm "soup bag" (the medicinal material accounts for 1 / 3 of the bag volume), and added 40% by volume with the volume and mass ratio of liquid material of about 16:1 Ethanol (diluted with 95% by volume of edible ethanol and distilled water), placed in the extraction tank, soaked overnight, heated in a water bath until the temperature of the liquid in the extraction tank reached 61°C, and refluxed for 3.1 hours by dipping. After the extraction is completed, pump the liquid medicine to the concentration tank, control the temperature at 55°C, and vacuum at -0.074MPa, and concentrate until the liquid density is about 1.1g / ml. Put the concentrated solution in a vacuum drying oven, set the drying temperature to about 60°C (vacuum degree is -0.092Mpa), dry for about 24 hours, crush and sieve to obtain the finished product. The FRAP value of...

Embodiment 2

[0029] The antioxidant active extract of citrus peel obtained in Example 1 is used as a food additive and added to daily food to prepare a food containing antioxidant active ingredients.

Embodiment 3

[0031] The antioxidant active extract of citrus peel obtained in Example 1 is added with conventional auxiliary materials, and made into oral liquids, capsules, tablets and other health products for consumption.

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Abstract

The invention discloses an anti-oxidation active extract of citrus peels as well as an extraction process and application thereof. The active extract of the citrus peels mainly contains a citrus flavonoid substance and pectic polysaccharide. The extraction process of the active extract of the citrus peels comprises the steps of preprocessing raw materials, refluxing and extracting by a dipping method, decompressing and concentrating and drying in vacuum. The invention takes the in-vitro oxidation resistance of the extract to combine with the extraction yield as indexes, adopts a response surface method to optimize the extraction process, has reasonable technological conditions and good effect stability and is suitable for industrialized production. The active extract of the citrus peels, which is obtained by extraction, has an obvious effect to a model mouse with senility caused by D-galactose and can lower the content of the MDA (malondialdehyde) of the plasma, the liver and the brain obviously; the activity of the SOD (superoxide dismutase) of the plasma, the liver and the brain is obviously enhanced; the activity of the GSH-Px (glutathione peroxidase) of the plasma and the liver is obviously enhanced; and the invention can be used for preparing an anti-oxidation medicine, an anti-oxidation food or an anti-oxidation health-care product.

Description

technical field [0001] The invention relates to the technical field of extracting effective components of citrus peels, in particular to an extract of active parts of citrus peels with antioxidative effect and its extraction process and application. Background technique [0002] my country is the main producer of citrus, and its cultivated area and total output rank among the top in the world. However, due to the lagging processing technology, the sales of fresh fruit are prone to seasonal surplus. The authentic medicinal material "Guang Chenpi" in Guangdong is derived from the dry and mature peel of Citrus reticulata 'Chachi', which contains a variety of natural antioxidant substances, such as flavonoids, pectin polysaccharides, etc. Guangdong local specialty. However, the current practical application of tea branch mandarin just stays in the primary development stage of the peel, and except for medicinal use, it is mostly only used as seasoning and preserved fruit. Citr...

Claims

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Application Information

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IPC IPC(8): A61K36/752A23L1/30A61P39/06A61K131/00A23L33/105
Inventor 黄庆华殷光玲周林莫云燕
Owner GUANGDONG PHARMA UNIV
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