The invention provides a method for producing
organic acid at a high
production rate through
fermentation of intermittent
backflow cells, which comprises the following steps of: performing
filtration sterilization on a fresh culture medium, introducing into a
fermentation tank, and inoculating high-density seed liquor into the
fermentation tank; controlling
organic acid fermentation production conditions of the used strain, when fermentation is performed until a small amount of
sugar residue is in fermentation liquor, discharging partial or all fermentation liquor to a filtering device for
processing, simultaneously supplementing a fresh germ-free culture medium into the fermentation tank, returning intercepted strain
cell concentrated solution to the fermentation tank to serve as a production strain for later use, wherein the filtered liquor is used for extracting
organic acid; and only when the
production rate of the organic acid is obviously reduced, not returning the strain
cell concentrated solution intercepted by the filtering device is not to the fermentation tank any more, and supplementing new high-density seed liquor and a fresh germ-free fermentation culture medium into the fermentation tank so as to perform a new round of production of organic acid at the high
production rate through fermentation of the intermittent
backflow cells. Through the method, high
biomass and high production rate are always kept in the organic acid fermentation production process, and the method has high industrial application value.