170 results about "P-Nitrobenzene" patented technology

Crude aniline is produced by hydrogenating nitrobenzene in the presence of a catalyst. This crude aniline is then purified by means of a single-step or multi-step distillation process in which aqueous alkali metal hydroxide solution is added to the crude aniline prior to distillation and / or during distillation of the crude aniline.

The invention discloses a method for treating nitrobenzene wastewater by using ozone biological aerated filter and application thereof and belongs to the field of sewage treatment. The treatment method comprises the following steps: (1) constructing a biological filter; (2) starting an air aerated biological filter; (3) starting an ozone biological aerated filter; (4) running the ozone biological aerated filter. The catalytic oxidation and the biological oxidation of ozone zeolite are integrated, the strong oxidative of the ozone is used for opening the ring of the nitrobenzene, the nitrobenzene after ring opening is used as an easily degradable matrix to participate in co-metabolism degradation of nitrobenzene, the removal effect of the nitrobenzene is improved, the biological film growing on the zeolite filler at the upper part of a reactor is used for degrading oxidation products, and the efficient degradation of the nitrobenzene is realized in the same reactor. Through the adoption of the biological aerated filter disclosed by the invention, removable efficiency of the nitrobenzene can reach 90% or above; the biological aerated filter has the advantages of small floor area, high nitrobenzene removal efficiency, convenient starting and simple operation.

The invention provides a method for preparing aniline through nitrobenzene hydrogenation. The method comprises the step of adopting a catalyst loaded with cobalt on a composite carrier for catalytic reaction, wherein the composite carrier is a composite carrier forming a zirconium oxide structure on an SBA-15 molecular sieve; and the catalyst is Co-zirconium oxide / SBA-15. The invention also provides a preparation method for the catalyst. The preparation method comprises the following steps: preparing the composite carrier, then impregnating the composite carrier, and loading cobalt onto the composite carrier in a hydrogen environment by using a high-temperature gas-phase reduction method so as to obtain the catalyst. The catalyst for preparing the aniline through nitrobenzene hydrogenation, which is prepared by adopting a gas phase reduction method, has the advantages of high cobalt nanoparticle dispersity, small particle size, large carrier specific surface area and novel catalyst structure. The catalyst is used for selective hydrogenation of nitrobenzene; reaction conditions are mild; catalytic activity is good; and high selectivity (more than 99%) and conversion rate (more than99%) can be simultaneously achieved in the reaction of preparing the aniline through nitrobenzene hydrogenation.

The invention discloses a liquid single reagent for detecting alpha-L-fucosidase and a preparation method thereof. The liquid single reagent contains a buffer solution, ethylenediamine tetraacetic acid, NaCl, a surface active agent, a stabilizer and a P-nitrobenzene chloride alpha-L-fucus pyranoside. The stabilizer contained in the liquid single reagent disclosed by the invention can not only effectively enhance the stability of the liquid single reagent, but also effectively eliminate the interference of sample heparin by being cooperated with the surface active agent, therefore detection accuracy and sensitivity are enhanced. A stability test result indicates that after the liquid single reagent for detecting the alpha-L-fucosidase is respectively preserved for 3 days at 42 DEG C, preserved for 14 days at 37 DEG C and preserved for 18 months at 2-8 DEG C, various properties are kept stable so as to indicate that the liquid single reagent disclosed by the invention has good stability and can resist the interference of at least 100 KU / L heparin contained in a sample.

The invention discloses a 2-carbonyl-3-phenylpropionic acid p-nitrobenzoyl hydrazone di-p-methyl benzyl tin complex of which the structural formula is shown in the description; in the formula, Ph is phenyl, and R is methyl benzyl. The invention further discloses a preparation method and application of the 2-carbonyl-3-phenylpropionic acid p-nitrobenzoyl hydrazone di-p-methyl benzyl tin complex in preparation of anti-cancer medicines.

The invention discloses a lecanicillium psalliotae strain with the preservation number of CGMCC NO: 5329. The strain can colonise spawns, two-year-old larvae and female adults at different life stages of rootknot nematode. Activations of chitinous substance degradative enzyme and excisionenzyme generated by the strain can be respectively determined through an N-acetyl glucosamine method and a p-nitrobenzene method, the enzymatic activities thereof can reach 3.98 U / h.mL and 0.38 U / h.mL, and higher activity of the produced chitinous substance enzyme can be detected at different temperature (27 DEG C-75 DEG C) and different pH (3.0-7.0); and the influence of chitinous substance enzyme extract produced by the strain on eclosion of rootknot nematode spawns is determined in vitro, and the inhibition ratio and the destruction ratio of enzyme solution on relative eclosion of the spawns are respectively 94.52 percent and 84.32 percent. The lecanicillium psalliotae strain disclosed by the invention is applied to biological control of crop rootknot nematodiasis, provides an effective way for protecting sweet potatoes, fruits, vegetables in north China and particularly controlling destructiverootknot nematodiasis, and has obvious ecological benefit, economic value and social value.

The invention provides a supported yolk-eggshell structure nano-catalyst. The supported yolk-eggshell structure nano-catalyst comprises a carrier and an active component; the carrier is a metal organic framework; the active component is double-transition metal nanoparticles with a plasma resonance effect; and the double-transition metal nanoparticles are embedded into the carrier, so that the active component and the carrier form a yolk-eggshell structure. Compared with like catalysts in the prior art, the catalyst provided by the invention absorbs visible light and converts light energy intoheat energy by utilizing the plasma resonance effect of the supported double-transition metal nanoparticles, so that the reaction condition of p-nitrostyrolene hydrogenation is converted into normal temperature and normal pressure; and the unique yolk-eggshell structure of the catalyst makes more active sites exposed, and a cavity between the yolk and the eggshell can enrich a reaction substrate and increase the contact area between the substrate and the active site, so that the catalyst shows efficient catalytic activity and reaction selectivity in the hydrogenation reaction of p-nitrostyrolene, and has a good application prospect.

The invention provides preparation of a high-temperature acidification corrosion inhibitor which is prepared from the following components in parts by weight: 50 to 60 parts of sulfathiazole solution, 10 to 15 parts of phenolic resin, 10 to 15 parts of dodecyl dimethyl benzyl ammonium chloride, 5 to 10 parts of aminopolysiloxane and 10 to 20 parts of diethylene glycol; the components for optimalpreparation comprise 60 parts of sulfathiazole, 15 parts of phenolic resin, 10 parts of dodecyl dimethyl benzyl ammonium chloride, 7 parts of aminopolysiloxane and 15 parts of diethylene glycol; and when in preparation, the components are sequentially added into a reaction kettle and stirred for 30 to 40 minutes to obtain the product, wherein the preparation of the sulfathiazole solution comprises the following steps: taking 45 to 50 parts of 2-aminothiazole and 45 to 50 parts of p-nitrobenzene sulfonyl chloride, adding into the reaction kettle, stirring, keeping the constant temperature to 40 DEG C for 2 to 3 hours, then adding 45 to 50 parts of sodium bicarbonate, and continuing to react for 4 to 5 hours to obtain the solution. The product still has good corrosion inhibiting effect and compatibility when used under the acidification condition of 150 to 180 DEG C.

The invention discloses a preparation method of a p-aminophenylacetic acid, which comprises the following steps of: adding p-nitrophenylacetic acid, ethanol and a catalyst into a pressure reaction kettle in a certain proportion, replacing air in the reaction kettle with nitrogen, feeding hydrogen into the reaction kettle, and controlling a certain pressure and temperature; after the reaction is performed for a period of time, standing the reaction kettle, cooling the obtained product to room temperature, opening the pressure reaction kettle, and extracting 60-80% solvent ethanol through evaporating; carrying out cooling crystallization, filtration and drying on the solvent ethanol so as to obtain a coarse product, and carrying out recrystallization on the coarse product by using ethanol, and carrying out active carbon decoloration on the obtained product so as to obtain white crystalline p-aminophenylacetic acid, wherein the mass ratio of the p-nitrophenylacetic acid, the ethanol to the catalyst is 1:10: (0.02-0.05), the mass concentration of the ethanol is 95%, the mass concentration of the catalyst is 3-8% Pd / attapulgite clay, the reaction pressure is 0.4-0.6 MP, the reaction time is 3-5 hours, and the reaction temperature is 30-60 DEG C. According to the invention, the catalyst is low in cost, less in application amount and convenient for recycling; the method is mild in reaction conditions, energy-saving and environment-friendly; the method is good in reaction selectivity, less in side effects, easy to realize purification, and high in yield; and through taking hydrogen as a raw material, the method is less in pollution, simple in post-processing, and low in production cost.

The invention discloses p-nitrophenoxy betulin (28) formyl ester and betulin derivatives synthesized therefrom, and a preparation method and an application thereof, and belongs to the technical fieldof pharmaceutical chemical. Four derivatives are synthesized with betulin as a matrix, that is to say, the tail end of a structure of the betulin is modified, a carbonacylation agent nitrophenyl chloroformate is introduced to a C-28 site, p-nitrophenoxy betulin (28) formyl ester is generated, and based on the p-nitrophenoxy betulin (28) formyl ester, four kinds of groups having biological activityand functionality are introduced. Specifically, with introduction of a structure of aminoethyl alcohol, the solubility is improved; with introduction of an N-amino morpholine group having a lysosomepositioning action and a triphenylphosphine active group having mitochondria targeted positioning, the product targetedly acts on cell organelles, the bioavailability is improved, and the higher biological activity is played; with introduction of a p-aminophenol structure, the synthesized compounds have certain antioxidant effects, and certain pharmacological activities are played by regulating the balance of redox in cells.

The invention provides an alkaline phosphatase detection kit, and belongs to the technical field of medical examination. The kit comprises a reagent 1, a reagent 2, a calibration material and a quality control material. The reagent 1 comprises the following main components: 2-amino-2-methyl-1-propanol (AMP buffer solution with the pH value of 10.0), magnesium acetate, PC300, zinc sulfate and Tween20. The reagent 2 is prepared from the following main components: 2-amino-2-methyl-propanol (AMP buffer solution with the pH value of 10.0), disodium p-nitrophenyl phosphate (4-NPP) and PC300. By adding ethyl acetate, PMX-200 or liquid paraffin into the reagent 1 and the reagent 2, the contact between the reagents and air is effectively reduced, the reaction between the main components in the reagents and oxygen is reduced, and the uncovering stability of the reagents is guaranteed.

The invention discloses a method for nitrifying nitrobenzene by using a micro-channel continuous flow reactor, and belongs to the technical field of preparation of chemical intermediates. The method specifically comprises the following steps: 1, preparing 65% nitric acid and 92% sulfuric acid into mixed acid according to a molar ratio of 1:3.0-10.0; 2, respectively inputting nitrobenzene and the mixed acid into a micro-channel continuous flow reactor for preheating, wherein the molar ratio of nitric acid in the nitrobenzene to nitric acid in the mixed acid is 1:1.05-1.25; 3, making the preheated nitrobenzene and the mixed acid enter a reaction module for reaction for 30-120s, and letting the reactants enter a collecting tank; and 4, performing cooling to 50-70DEG C, adding an organic solvent, stirring the substances uniformly, performing standing for layering to obtain an organic layer at the upper layer and an inorganic layer at the lower layer, and respectively conveying the organiclayer and the inorganic layer into an organic storage tank and an inorganic storage tank. According to the invention, the concentrations of nitric acid and sulfuric acid are reduced; and the added organic solvent does not reduce the concentration of sulfuric acid in the process of separating dinitrobenzene from sulfuric acid, thereby achieving the goal of sulfuric acid reutilization.