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217 results about "Hypertensive disease" patented technology

Hypertensive heart disease. Hypertensive heart disease refers to heart problems that occur because of high blood pressure that is present over a long time. Causes. High blood pressure means the pressure inside the blood vessels (called arteries) is too high. As the heart pumps against this pressure, it must work harder.

Heterocyclic compounds and their use as angiotensin antagonists

InactiveUS6100252AHigh yieldPotent angiotensin II receptor antagonistic activityBiocideNervous disorderDiseaseHeart disease
Compounds shown by the above formula or salt thereof show a strong angiotensin II antagonistic activity and hypotensive action and CNS activity, and are useful as therapeutic agents of circulatory diseases such as hypertensive diseases and heart diseases (e.g. hypercardia, heart failure, cardiac infarction), strokes, cerebral apoplexy, nephritis, atherosclerosis, Alzheimer's disease, senile dementia, etc.
Owner:TAKEDA PHARMACEUTICALS CO LTD

Preparation method for metoprolol salt

The invention discloses a preparation method for metoprolol salt, which includes the steps of utilizing p-(2-methoxyethyl) phenol and epoxy chloropropane as raw materials and water or ethanol as dissolvent, and obtaining 3-[4-(2-methoxyethyl phenoxy)]-1,2-epoxypropane under the action of strong alkali; and utilizing water as dissolvent, carrying reaction between the 3-[4-(2-methoxyethyl phenoxy)]-1,2-epoxypropane and isopropylamine so that metoprolol alkali is obtained, and then carrying out reaction between the metoprolol alkali and saturated monohydric alcohol liquor of organic acid or saturated monohydric alcohol liquor of hydrochloric acid, so that the metoprolol salt is obtained. Clinically, hydrochloride, succinate, fumarate or tartrate of the compound is utilized as common medicinefor treating hypertensive disease, coronary disease, congestive heart failure and arrhythmia. The raw materials of the preparation method are cheap and easy to obtain, the water and the ethanol are utilized as the dissolvent so as to hardly cause pollution, the method is convenient in operation, high in purity of the prepared metoprolol salt, high in yield, lower in cost and extremely suitable for mass production.
Owner:SHANDONG JINHE DRUG RES DEV

Compositions and methods related to heart failure

The invention provides methods for (a) prolonging time to hospitalization for heart failure; (b) prolonging time to first hospitalization for heart failure; (c) reducing the total number of days a patient with heart failure spends in the hospital for heart failure for a single hospital stay (i.e., reducing the duration of a single hospital stay for a patient with heart failure); (d) reducing the total number of days a patient spends in the hospital for heart failure for multiple hospital stays (i.e., two or more hospital stays); (e) reducing the number of hospital admissions for heart failure; (f) reducing mortality and reducing hospitalizations for heart failure (e.g., the total number of days in the hospital and / or the number of hospital visits); (g) increasing the left ventricular ejection fraction in a heart failure patient; (h) treating a sexual dysfunction (e.g., erectile dysfunction and female sexual dysfunction) (j) treating a headache in a heart failure patient by administering a non-steroidal antiinflammatory compound (i.e., NSAIDs); (k) treating a heart failure patient who has a history of hypertension (but who is not currently diagnosed with hypertension); (l) improving the quality of life in a heart failure patient based on the Minnesota Living with heart failure questionnaire; (m) decreasing the levels of B-type natriuretic peptide; (n) treating hypertension in a heart failure patient; (o) lowering blood pressure in a heart failure patient; (p) treating labile hypertension; (q) treating idiopathic hypertension; (r) increasing patient compliance with medication dosing in a heart failure patient; (s) treating hypertension in a patient with a dilated heart; (t) treating ischemic disease and / or coronary artery disease; and (u) reducing cardiomegaly in a patient in need thereof comprising administering to the patient a therapeutically effective amount of (i) a hydralazine compound or pharmaceutically acceptable salt thereof, (ii) isosorbide dinitrate and / or isosorbide mononitrate, and (iii) optionally at least one compound selected from the group consisting of angiotensin converting enzyme inhibitors, β-adrenergic antagonists, angiotensin II antagonists, aldosterone antagonists, cardiac glucosides (digitalis), and diuretic compounds.
Owner:NITROMED

Grassroots medical platform and hypertension patient monitoring method based on grassroots medical platform

The invention discloses a hypertension patient monitoring method based on a grassroots medical platform. The hypertension patient monitoring method comprises that the grassroots medical platform monitors the blood pressure value of a user at the preset time with a preset monitoring period according to a user diagnosis and treatment plan acquired from a network hospital platform; the grassroots medical platform compares the blood pressure value of the user at the preset time with the blood pressure threshold at the corresponding time in the user diagnosis and treatment plan, and the comparison result within the preset monitoring period is recorded; the grassroots medical platform determines a blood pressure monitoring result within the monitoring period according to the comparison result within the preset monitoring period, and sends a blood pressure adjusting plan corresponding to the blood pressure monitoring result to the user in order to make the user execute the blood pressure adjusting plan. The invention also discloses a grassroots medical platform. The grassroots medical platform is in butt joint with the network hospital platform, parameter monitoring, prompting and intervention are carried to a hypertension patient according to the user diagnosis and treatment plan, and therefore the treatment progress of the hypertension patient is accelerated, and the treatment effect of the hypertension patient is improved.
Owner:ANYCHECK INFORMATION TECH

Traditional Chinese medicine for treating apoplexy sequela, hypertension, hyperlipidemia and hyperviscosemia

The invention discloses a traditional Chinese medicine for treating apoplexy sequela, hypertension, hyperlipidemia and hyperviscosemia. The traditional Chinese medicine is prepared from the following bulk pharmaceutical chemicals as active ingredients in parts by weight: 100-120 parts of radix astragali seu hedysari, 10-15 parts of radix paeoniae rubra, 10-12 parts of herbs of false chinese swertia, 8-10 parts of rhizoma ligustici chuanxiong, 8-10 parts of semen persicae, 3-5 parts of flos carthami, 8-10 parts of lumbricus, 20-25 parts of radix salviae miltiorrhizae, 8-10 parts of hirudo, 10-15 parts of radix dipsaci, 12-15 parts of herba taxilli, 8-10 parts of cortex eucommiae, 28-30 parts of raw hawthorn, 4-5 parts of ramulus cinnamomi, 8-10 parts of bulbus allii macrostemonis, 12-15 parts of radix cyathulae, 18-20 parts of radix puerariae, 5-6 parts of scorpio, 28-30 parts of folium ginkgo, 25-30 parts of herba erigernotis, 8-10 parts of rhizoma alismatis, 28-30 parts of poria, 25-30 parts of semen ziziphi spinosae, 18-20 parts of semen cassiae, 18-20 parts of scorched medicated leaven and 10-15 parts of fructus ligustri lucidi. The traditional Chinese medicine can achieve the efficacies of invigorating qi and promoting blood circulation, promoting circulation and removing stasis, stimulating the menstruational flow and dissipating the phlegm, and tonifying the kidney and reducing the blood pressure, and is a first-choice medicament of the patients with apoplexy sequela, hypertension, hyperlipidemia and hyperviscosemia, and has obvious treatment effect.
Owner:朱黎明

Nanometer Chinese medicine element anion far infrared electromagnetic wave pollution preventing and blood pressure reducing health care coat

The invention relates to a nanometer Chinese medicine element anion far infrared electromagnetic wave pollution preventing and blood pressure reducing health care coat which belongs to the technical field of production of multifunctional health fabric trappings and clothes. The hypertension is a common frequently-occurring disease which is harmful to the health of the human body, seriously influences the cardio-cerebral system and other systems, is very difficult to cure and causes the blood pressure to raise often as soon as the people forget taking medicines. In the invention, micro element anion far infrared electromagnetic wave pollution preventing mixed nanomaterials are added into a multifunctional spinning solution for producing fabrics, and micro element anion far infrared electromagnetic wave pollution preventing material molecules are slowly and continuously released through contacting with skin, therefore, the in-vivo element balance is effectively regulated, the blood pressure circulation and the blood vessel elasticity are enhanced, and the immunity and the capacity of resisting diseases are improved. Therefore, the invention is a natural dressing therapy which can stably reduce the blood pressure and keep the body healthy and the vigor plentiful in the daily dressing.
Owner:成钢

A kind of traditional Chinese medicine capsule for treating high blood pressure

The invention relates to Chinese medicinal capsules for treating hypertension. The capsules are processed from bark of eucommia, wild chrysanthemum, peach kernel powder, root of red-rooted salvia, felicitous plant, safflower, corydalis tuber, bighead atractylodes rhizome, root of kudzu vine, glossy privet fruit, feather cockscomb seed, flower of Chinese scholartree, fleeceflower root, pseudo-ginseng, selfheal spike, uncaria, earthworm, bark of tree peony root, hawthorn, lotus plumule, semen coicis, folium ginkgo bilobae and medlar. The capsules have the effects of promoting blood circulation and removing blood stasis, regulating vital energy and restoring menstrual flow, clearing heat and removing toxin, cooling blood and stopping bleeding, calming the liver to stop the wind, nourishing yin and tonifying liver and kidney, tonifying the spleen to benefit the lung and softening blood vessel and has good meridian activating and pressure releasing effects. A pure Chinese medicinal product can be used for various types of hypertension patients, is low in cost, has good in therapeutic effect, does not have any toxic or side effect, is not required to be decocted, and is convenient to carry and take; and the capsules are clinically used for curing 1,000typical cases, and the effectiveness ratio reaches 100 percent.
Owner:湖南苑医堂中医药开发有限公司

Traditional Chinese medicinal composition for treating hypertension and preparation method thereof

The invention relates to the field of medicines, and particularly relates to a traditional Chinese medicinal composition for treating hypertension. The composition is prepared from the following raw materials in parts by weight: 100-300 parts of gastrodia elata, 500-1500 parts of eucommia ulmoides, 300-900 parts of apocynum venetum, 100-300 parts of earthworm, 100-300 parts of uncaria rhynchophylla, 100-300 parts of achyranthes root, 300-600 parts of salvia miltiorrhiza, 300-900 parts of seaweed, 300-900 parts of astragalus membranaceus, 250-500 parts of radix paeoniae alba, 300-900 parts of cassia occidentalis, 100-300 parts of tabasheer, 250-500 parts of scutellaria baicalensis, 300-900 parts of gynostemma pentaphylla, 200-400 parts of pseudo-ginseng, 200-400 parts of ligusticum wallichii and the like. The composition can be used for treating headache, dizziness, numbness of limbs, insomnia and other symptoms caused by hypertension, is prepared from traditional Chinese medicinal materials, is safe and effective, does not have remarkable side effects, and can be used for assistant treatment of cervical spondylosis, insufficient brain blood supply and other diseases.
Owner:张伯华

Medicinal composition used for tonifying qi and invigorating pulse, preparation method thereof and application thereof

The invention belongs to the field of medicament, and particularly relates to a medicinal composition used for tonifying qi and invigorating pulse, a preparation method thereof and application thereof. The invention provides a brand-new medicinal composition with functions of tonifying qi and invigorating pulse for treating cardiovascular and cerebrovascular diseases. The medicinal composition is prepared from the following raw material medicaments in part by weight: 9 to 16 parts of astragalus, 2 to 5 parts of acanthopanax bark, 1 to 5 parts of rhubarb, 2 to 5 parts of hawthorn fruit, 3 to 6 parts of Sanchi, 2 to 5 parts of Szechuan lovage rhizome, and 2 to 9 parts of Chinese angelica. The medicinal composition has the effects of tonifying original qi, tonifying spleen and dredging channels, and can be used for treating the diseases such as coronary disease (myocardial infarction and angina pectoris), ischemic and hemorrhagic cerebrovascular accidents (cerebral infarction and cerebral hemorrhage), high blood pressure, hyperlipidaemia, fatty liver and the like.
Owner:潘畅

Prediction method of high blood pressure based on incremental neural network model and prediction system

InactiveCN106650206AProactively analyze periodicityActive analysis of regularityMedical automated diagnosisSpecial data processing applicationsDaily livingNetwork model
The invention discloses a prediction method of high blood pressure based on incremental neural network model. The method comprises the steps that a database of daily data of high blood pressures is built; a neural network model is trained; daily living data are collected and sent to a server, and are saved to a daily data sheet of a user; daily data are extracted from the daily data sheet of the user, and form an N dimensional vector, after the normalization is done, the data are input in a hypertensive pathological neural network model to conduct probabilistic prediction of the hazard level of high blood pressure; the value W of the hazard level of high blood pressure is judged whether or not being larger than or equal to 3 using a smart home high blood pressure care equipment; when a user receives a warning from an annunciator, the user goes to the hospital to check, the check results are sent back to the server through the smart home high blood pressure care equipment, the servers judges whether or not the check results are correct; an incremental calculation method is carried out when the check results are incorrect, and the neural network model is dynamically corrected. The method and system are accurate in prediction, and the neural network model is tailor made for every user.
Owner:湖南老码信息科技有限责任公司

Chewing gum contg. mulberry leaf function component and process for preparing same

The present invention relates to a chewing gum comprising functional ingredients of mulberry leaves, which allows high absorption of the functional ingredients of mulberry leaves, and a method for the preparation of the chewing gum. This chewing gum containing functional ingredients of mulberry leaves includes: 15-30% (w / w) gum base, 60-80% (w / w) sugar alcohol, 0.1-0.5% (w / w) tenderizer, 0.1 -1.0% (w / w) humectant, 0.1-0.5% (w / w) emulsifier, 0.5-2.5% (w / w) flavoring agent, 0.01-10.0% (w / w) functional ingredients of mulberry leaves and 0.1-2.0% (w / w) fruit juice concentrate. This chewing gum containing functional ingredients of mulberry leaves can be practically applied to prescribed food and food replacement for patients suffering from constipation, diabetes and hypertension.
Owner:HONG YOUNG FOOD

Potassium-free sodium-reducing granulated edible salt and preparation method thereof

The invention provides potassium-free sodium-reducing granulated edible salt. The potassium-free sodium-reducing granulated edible salt comprises the following components in percentage by weight: 50-75% of sodium chloride, 1-30% of yeast extract and the balance of auxiliary materials, wherein the sum of the weight percentages of the components is 100%. The potassium-free sodium-reducing granulatededible salt is designed according to the principle that saltiness and freshness are synergistic and salt is reduced but flavor is not reduced; under the condition that potassium chloride is not added, the purpose of reducing the salt by more than 25% can be achieved; the potassium-free sodium-reducing granulated edible salt is different from common sodium-reducing salt added with the potassium chloride in the market; due to the fact that the potassium chloride is not added, the sodium-reducing salt is also suitable for hypertension patients who take hypotensive drugs, and is more widely available than the common sodium-reducing salt. Through a granulating process, the sodium-reducing salt is more attractive in appearance and more convenient to use; and meanwhile, an anti-caking agent doesnot need to be added.
Owner:ENG TECH INST CO LTD OF CNSIC
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