38 results about "Glycosamine" patented technology

A medicinal composition in the form of tablet, capsule, dispersing tablet, effervescent tablet, etc for treating the various osteoarthritides is prepared from aminoglucose hydrochloride, chondroitin sulfate and pharmacologically acceptable additives.

The invention relates to a preparation method of a glycosylated surfactant. The preparation method comprises the following steps: firstly weighing glucose, dissolving the glucose in a methanol solution, then adding long-chain n-alkylamine according to the molar ratio of long-chain n-alkylamine to glucose of (1:1)-(1:6) to react with glucose to prepare alkyl glucosimine, then adding an excessive amount of NaBH4 to perform reaction to prepare an alkyl glycosamine crude product; sequentially washing the crude product with iced anhydrous ethanol and methanol solutions, and performing suction filtration to obtain alkyl glycosamine; further dissolving prepared alkyl glycosamine in the methanol solution, then adding glyoxylic acid according to the molar ratio of glyoxylic acid to alkyl glycosamine of (2:1)-(6:1) to react with alkyl glycosamine so as to prepare a glycosylated surfactant crude product; removing a reaction solvent and unreacted glyoxylic acid in the crude product by a rotating evaporation instrument to obtain the glycosylated surfactant. According to the preparation method provided by the invention, the novel glycosylated surfactant is prepared by reaction of glyoxylic acid and self-made alkyl glycosamine.

This invention relates to a process for the preparation of glucosamine hydroiodide, glucosamine pyruvate, glucosamine phosphate or their mixtures with glucosamine hydrochloride, by electrodialysis. Starting from glucosamine hydrochloride, the exchange of the Cl⁻ for an anion selected from the group consisting of SO₄ ⁻², I⁻, CH₃COCOO⁻ and PO₄⁻³ takes place during the process. The electrodialysis, that comprises a cathode, anode, and means of separation composed of anion exchange membranes, cation exchange membranes, bipolar membranes or by other suitable means of separation. This invention also relates to a glycosamine sulphate containing chlorides obtainable by the process, and its therapeutic use.

The invention relates to a synthesis method of a highly ordered dendronized heterogeneous glycopolymer containing various glycosyl groups. The method comprises the following steps: (1) adding anhydrous triethylamine into a dichloromethane solution of pentafluorophenol under an ice bath condition, then adding acryloyl chloride for reaction, and after the reaction is finished, washing, drying and purifying to obtain a compound PFPA; (2) carrying out polymerization reaction on the compound PFPA, a chain transfer agent and an initiator to obtain a polymer pPFPA; (3) mixing the polymer pPFPA with dendronized glycosamine, and carrying out ammonolysis reaction to obtain a glycopolymer; and (4) adding the glycopolymer into a sodium methoxide/methanol solution to react, and purifying after the reaction is finished, thereby obtaining the target product, namely the dendronized heterogeneous glycopolymer containing various glycosyl groups. Compared with the prior art, the method has the advantages that the advantages of RAFT polymerization and post-modification are combined, the glycopolymer with the ordered structure is obtained, particularly the regular heterogeneous glycopolymer is obtained, and a universal platform and the like are provided for preparation of the functional glycopolymer.

The invention provides a hepatic failure detection reagent and a preparation method thereof, and the detection reagent is prepared by mixing the following reagents: a reagent A, which is prepared by adding 0.5-5% by mass of SDS into an ammonium bicarbonate solution with a concentration of 10 mM; a reagent B, which is prepared by mixing 0.01-10 U/10 [mu] L of glycosamine acylase and 0.01-10 U/10 [mu] L of sialidase, wherein the pH value of the mixed solution is 4-9; a reagent C, which is prepared by dissolving 8-aminopyrene-1, 3, 6-trisulfonic acid in DMSO (dimethylsulfoxide), and the concentration of the reagent C is 0.01 mM to 1M; and a reagent D: a stop solution. According to the invention, a glycome map in serum is determined by a detection reagent, and a peak value is quantified for statistical analysis, so that the establishment method of the hepatic failure serum glycome map model is provided for detecting hepatic failure.

The invention relates to a mixture of natamycin and mycosamine and to the use of these mixtures for sanitizing and subsequently preserving foodstuffs and beverages, and to a process for incorporatingthe claimed mixtures into foodstuffs and beverages.

The invention provides an esophageal cancer detection reagent and a preparation method thereof, and the detection reagent is prepared by mixing the following reagents: a reagent A which is prepared by adding 0.5-5% by mass of SDS into an ammonium bicarbonate solution with a concentration of 10 mM; a reagent B which is a mixed solution prepared by mixing 0.01-10 U/10 [mu]L of glycosamine acylase and 0.01-10 U/10 [mu]L of sialidase and has a pH value of 4-9; a reagent C which is prepared by dissolving 8-aminopyrene-1,3,6-trisulfonic acid in DMSO (dimethylsulfoxide) and has a concentration of 0.01 mM to 1M; and a reagent D which is a stop solution. According to the invention, a glycome map in serum is determined by a detection reagent, a peak value is quantified for statistical analysis, and the establishment method of the esophageal cancer serum glycome map model is provided for detecting esophageal cancer.

The invention discloses an amphoteric glycolipid biosurfactant and a preparation method thereof, and belongs to the technical field of biological materials. The amphoteric glycolipid biosurfactant comprises fatty acid, polysaccharide, amphoteric glycolipid biosurfactant molecules, glycosamine, lipopeptide, ethanol, fatty amine and the like. The preparation method of the amphoteric glycolipid biosurfactant comprises the following steps: (1) culturing: carrying out staged culture by adopting three bacteria; (2) separating: adjusting the pH value of the obtained fermentation culture solution, centrifuging, and recovering a middle-layer clear solution; (3) performing acid precipitation: adjusting the pH value of the middle-layer clear solution, and then performing refrigerating precipitation;(4) filtering: collecting the precipitate by adopting a ceramic membrane, then dissolving the precipitate, and filtering again to obtain an aqueous solution; (5) concentrating: concentrating the aqueous solution in vacuum to obtain a concentrated aqueous solution; and (6) obtaining the finished product: adding the above components into the concentrated aqueous solution, and stirring. The preparedamphoteric glycolipid biosurfactant is a high-quality amphoteric glycolipid biosurfactant.

The glycosamine milk product is ewe/cow milk, semi-defatted ewe/cow milk, defatted ewe/cow milk, whole ewe/cow milk powder, defatted ewe/cow milk powder or yoghourt connecting glycosamine sulfate or glycosamine hydrochloride in 0.1-5 wt% and one or several of vitamin A, vitamin D, vitamin E and sodium glycocholate in 0.01-3 wt%. It is prepared through adding glycosamine sulfate or glycosamine hydrochloride and vitamin A, vitamin D, vitamin E and sodium glycocholate into the milk product through stirring, and high temperature sterilization. The present invention has the synergistic effect of the nutritious components in milk, glycosamine sulfate or glycosamine hydrochloride and vitamin A, vitamin D, vitamin E and sodium glycocholate, and thus calcium replenishing and other health functions, especially for the old people.

The invention discloses a plant infusion nutrient solution and a preparation method thereof. The solution comprises inorganic nutrient components, organic nutrient components and plant growth regulator components. The plant infusion nutrient solution can promote the growth of plants and increase the biomass of the plants, amino-oligosaccharin and 1-[4-(N-2-methoxybenzamide sulfonyl)phenyl]-3-methyl-urea are applied in a combined mode, and glycosamine and dicamba dimethylamine salt are applied in a combined mode, so that the plant infusion nutrient solution has a remarkable synergistic interaction function.

The invention provides a prostate cancer detection reagent and a preparation method thereof, and the detection reagent is prepared by mixing the following reagents: a reagent A which is prepared by adding 0.5-5% by mass of SDS into an ammonium bicarbonate solution with a concentration of 10 mM; a reagent B which is a mixed solution prepared by mixing 0.01-10 U/10 [mu]L of glycosamine acylase and 0.01-10 U/10 [mu]L of sialidase and has a pH value of 4-9; a reagent C which is prepared by dissolving 8-aminopyrene-1,3,6-trisulfonic acid in DMSO (dimethylsulfoxide) and has a concentration of 0.01 mM to 1M; and a reagent D which is a stop solution. The invention provides a method for establishing a model of a serum glycome map of prostate cancer to detect the prostate cancer by measuring the glycome map in the serum through a detection reagent and quantifying peak values for statistical analysis.

The present invention relates to new generation of gentamicin and its preparation process and use. It is prepared via adding glutamic acid, sodium glutamate or glutamic amine into the conventional deep red micromonad fermenting culture medium comprising corn powder, starch, yeast powder or soybean powder, potassium nitrate, calcium carbonate, ammonium sulfate, peptone and cobalt chloride, one or several kinds of additives are added selected from: rice powder, millet powder, fructose, glycosamine, ferric gluconate, zinc chloride, ferrous citrate, ferrous lactate, vitamin B12, etc. The gentamicin of the present invention, gentamicin C1, has the advantages of high gentamicin C1 content and less toxic side effect. The product of the present invention is one kind of antibiotic for human and animal.