The invention discloses anti-deformation fluororubber as well as a preparation method and application thereof, and belongs to the technical field of rubber and plastic sealing. The anti-deformation fluororubber comprises the following preparation raw materials in parts by weight: 100 parts of fluoroperoxide rubber, 3 parts of metal oxide, 0-20 parts of a first filler, 10-25 parts of a second filler, 0-3 parts of a processing aid, 1.0-3.0 parts of peroxide and 2.4-3.0 parts of a cross-linking agent, wherein the second filler is a layered filler. Through adjustment of a filler network, the fluororubber is filled with the layered filler with good rigidity and high radius-thickness ratio, so that the deformation-resistant fluororubber obtains excellent dimensional stability under the synergistic supporting action of a cross-linked network and the filler network, and is suitable for thin products within 1mm; therefore, the deformation capability of thin products in the online assembly, storage and transportation processes is solved, and meanwhile, six function tests required by the power battery sealing element can be met.