The invention discloses a cleaning and drying device for medical instruments. The cleaning and drying device comprises a box. Water outlets are formed in the bottom of the inner wall of the box. A support is fixedly arranged at the bottom of the inner wall of the box. One side of the support is fixedly connected with a lower sliding plate. The surface of the lower sliding plate is covered with a water absorption sponge. The bottom end of the lower sliding plate is in lap joint with the upper surface of a bearing plate. A containing groove is formed in the upper surface of the bearing plate, and a heating piece is arranged in the bearing plate. According to the cleaning and drying device for the medical instruments, a high-pressure spray head is arranged, so that the medical instruments are cleaned fast; ultraviolet lamps are arranged, so that the effect of disinfecting the medical instruments is achieved; the sliding plate and the water absorption sponge are arranged, so that the effects of sliding down and water absorption on the instruments are achieved; a filter device is arranged in an air chamber, so that the effect of filtering out impurities in air is achieved; and the heating piece is arranged, so that the effect of heating the bearing plate and the instruments on the bearing plate is achieved.