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286 results about "Cucurbituril" patented technology
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Cucurbiturils are macrocyclic molecules made of glycoluril (=C₄H₂N₄O₂=) monomers linked by methylene bridges (-CH₂-). The oxygen atoms are located along the edges of the band and are tilted inwards, forming a partly enclosed cavity. The name is derived from the resemblance of this molecule with a pumpkin of the family of Cucurbitaceae.
Novel synthetic binding pairs and uses thereof
InactiveUS20060292570A1Efficient preparationEfficient comprehensive utilizationBioreactor/fermenter combinationsBiological substance pretreatmentsDendrimerOligomer
Derivatized cucurbiturils can be efficiently prepared and utilized for forming cucurbituril assemblies. These cucurbituril assemblies, in turn, can form affinity binding pairs with polyamines structures that are designed capable of binding to these assemblies. The resulting affinity pairs are highly advantageous over the presently known affinity pairs and therefore can be efficiently utilized in a myriad of application. Thus, according to one aspect of the present invention there is provided a cucurbituril comprising at least one functional group covalently attached hereto, whereby the at least one functional group being for forming an assembly of at least two cucurbiturils. According to further features in preferred embodiments of the invention described below, the cucurbituril is selected from the group consisting of CB[5], CB[6], CB[7], CB[8] and CB[n], wherein n is an integer that equals to or is lower than 20. Preferably the cucurbituril is selected from the group consisting of CB[5], CB[6], CB[7] and CB[8]. According to still further features in the described preferred embodiments the assembly is selected from the group consisting of a dimer, a trimer, a polymer, an oligomer, a dendrimer and a cluster of the cucurbituril.
Owner:TECHNION RES & DEV FOUND LTD
Seven-membered cucurbituril-rare earth metal linear tubular supramolecular polymer, preparation and application thereof
InactiveCN102516550AStructure ConfirmationEasy to operateOther chemical processesPhysical chemistryCucurbituril
The invention provides a seven-membered cucurbituril-rare earth metal linear tubular supramolecular polymer and a synthetic method. When cadmium chloride exists, the seven-membered cucurbituril-rare earth metal linear tubular supramolecular polymer is formed by seven-membered cucurbituril (Cucurbit [7] uril and Q [7]) and rare-earth metal salt (Ln (NO3)3 or LnCI3) in 6M hydrochloric acid solution. According to the seven-membered cucurbituril, dosing mole ratio of the rare-earth metal salt to the cadmium chloride ranges from 1:6 to 8:2-8, and mixture of the rare-earth metal salt and the cadmium chloride are heated and mixed evenly and stand for several days under normal temperature to form a target compound. The method has the advantages of being simple in the synthetic method, easy and simple to operate, high in productivity (between 60% and 80%), short in period and the like. Compared to pure seven-membered cucurbituril, the seven-membered cucurbituril-rare earth metal linear tubularsupramolecular polymer synthetized by the method has strong adsorption to methyl alcohol, ethanol and acetone.
Owner:GUIZHOU UNIV
Calixarene constructed supramolecular polymer material and preparation method thereof
InactiveCN102304141AEasy to prepare and effectiveEasy to operateOrganic chemistryMethyl ViologenPolymer science
The invention discloses a calixarene constructed supramolecular polymer material. The chemical formula of a repeat unit of the material is C210H206N72O64S8; and the material consists of ethyl-bridged p-sulfonated calix[4]arene, cucurbit[8]uril and hexyl-bridged methyl viologen, wherein the ethyl-bridged p-sulfonated calix[4]arene and the cucurbit[8]uril serve as a large-ring host, the hexyl-bridged methyl viologen serves as a guest, and the supramolecular polymer with a host-guest inclusion structure is constructed through host-guest bonding. The invention has the advantages that: by the recognition advantage of the p-sulfonated calix[4]arene and the cucurbit[8]uril on specific groups of the viologen, a fibrous polymer material is prepared by a simple and feasible solution mixing method, and the method is easy to implement, high in yield, convenient and effective; and by a chemical reduction means of adding hydrazine hydrate, the polymer material can be well reduced and depolymerized,and the supramolecular polymer material has wide application prospect in the field of materials.
Owner:NANKAI UNIV
Inclusion compound comprising cucurbituril derivatives as host molecule and pharmaceutical composition comprising the same
The present invention provides an inclusion compound having a cucurbituril derivative of the formula 1 as a host molecule and a metal complex of the formula 2 as a guest molecule. A pharmaceutical composition having an anticancer effect can be obtained by using the inclusion compound according to the present invention. The pharmaceutical composition can prevent effective components from being biologically degraded in vivo and can exhibit continuous drug effect for a long time just by a single dosage by controlling the release time of the platinum complex once it reaches target tumor cells.
Owner:POSTECH ACAD IND FOUND
Solid phase microextraction coating of hydroxyl cucurbituril as well as preparation method and application thereof
InactiveCN103157453AIncrease surface areaHigh selectivityIon-exchange process apparatusComponent separationPotassium persulfateChemical reaction
The invention discloses a solid phase microextraction coating of a hydroxyl cucurbituril as well as a preparation method and an application thereof, relates to an analyzing sample pre-treatment technology, and belongs to the technical field of analytical chemistry. The solid phase microextraction coating is characterized in that a common pentabasic cucurbituril or six-membered cucurbituril is subjected to potassium peroxodisulfate oxidation and cation exchange resin separation and purification so as to obtain the hydroxyl cucurbituril through, the hydroxyl cucurbituril is bonded on a sol-gel mesh through a chemical reaction so as to obtain the solid phase microextraction coating, the coating is utilized to prepare a solid phase microextraction fibre which is combined with a gas chromatography, the environmental water sample containing polycyclic aromatic hydrocarbon is analysed, and the coating is utilized to prepare a solid phase microextraction stirring rod which is combined with a high performance liquid chromatography so as to analyze non-steroid antiinflammatory drugs. The solid phase microextraction coating provided by the invention has the advantages that the superficial area of the coating is large, and the extraction capacity is large; and the solid phase microextraction coating is a novel solid phase microextraction coating, is used for analyzing, high in selectivity, low in detection limitation, wide in linearity range, and good in selectivity.
Owner:GUIZHOU UNIV
Cucurbituril-based hydrogels
ActiveUS20150110772A1Increase shear rateIncrease moisture contentPeptide/protein ingredientsPharmaceutical non-active ingredientsCross-linkCucurbituril
The invention provides hydrogel, wherein the hydrogel has a supramolecular cross-linked network obtainable or obtained from the complexation of an aqueous composition including a host, such as cucurbituril, and one or more polymers having suitable guest functionality. One or more polymers in the aqueous composition may have a molecular weight of 50 kDa or more, such as 200 kDa or more. The hydrogel may hold a component, such as a therapeutic compound or a biological molecule. The hydrogels are suitable for use in medicine.
Owner:CAMBRIDGE ENTERPRISE LTD
Melon ring and method of synthesizing substituted melon ring
The invention relates to a cucurbituril and a synthetic method replacing the cucurbituril, which is an organic chemical heterocyclic compound, in particular to a compound named cucurbituril and a synthetic method replacing the cucurbituril. The synthetic method is that the glycolurils dimer is used as raw material and is heated and reacted with the epoxy glycolurils or the epoxy glycolurils derivatives and the formaldehyde in the hydrochloric acid medium under 90 DEG C. to 100 DEG C. for 1h to 2h; the cucurbituril is gained after condensation, filtration, separation and purification. The mixture is calculated based on the quantity of the material, and the glycolurils dimer : epoxy glycolurils or epoxy glycolurils derivatives : formaldehyde equals to 1 : 0 to 4 : 0 to 4, wherein, the epoxy glycolurils or epoxy glycolurils derivatives and the formaldehyde can not be zero at the same time, and the concentration of the hydrochloric acid is 3mol / L to 12mol / L. The invention can overcome the defect that the distribution of the cucurbituril in the product and the quantities and position of the substituent in the cucurbituril in the traditional synthetic method of the cucurbituril are difficult to control.
Owner:GUIZHOU UNIV
Cucurbituril subject-object based chemical nano structure membrane and preparation method and application thereof
InactiveCN101792115AHighly Sensitive Optical ResponseSensitive Optical ResponseIndividual molecule manipulationFluorescence/phosphorescenceObject basedCompound (substance)
The invention relates to a cucurbituril subject-object based chemical nano structure membrane. Chitosan solution is adopted to modify substrate, mutual action of cucurbituril and chitosan and hydrophobic effect of cucurbituril are utilized to fix dye molecule on the surface of the modified substrate, thus obtaining the nano structure membrane. The nano structure membrane of the invention has highselectivity and high sensitivity on nitro-containing explosive molecule, and preparation method is simple, cost is low, and the nano structure membrane is easy to be processed into device. The invention can be used for detecting trace of nitro-containing explosives including TNT, DNT, PETN, HMX and RDX and provides technical support for national security detection.
Owner:TSINGHUA UNIV
Calabash [7] carbamide aniline nano-supermolecule conducting polymer, method for preparing same and use
InactiveCN101307142AEasy to manufactureAvoid strict restrictionsConductive polymerOxidation-Reduction Agent
The invention relates to a novel nano supermolecular conductive polymer, a method for preparing the same and an application of the same. The novel nano supermolecular conductive polymer is obtained by polymerization of cucurbit (7) urea and aniline in water solution. The synthetic process of the novel nano supermolecular conductive polymer is completely performed in water phase, and the whole process is easy and feasible. As shown by the results of AFM and TEM experiments, the cucurbit (7) urea and aniline nano supermolecular conductive polymer takes the form of one dimensional nanometer linear aggregate. Moreover, compared with polyaniline synthesized by the prior art, the electrochemic property of the nano supermolecular conductive polymer is obviously different. Due to the stabilization of the cucurbit urea on cationic free radicals, the cucurbit (7) urea and aniline nano supermolecular conductive polymer can perform reversible redox process within wide pH value range. The nano supermolecular conductive polymer has wide application prospect in the nano supermolecular material technical field.
![Calabash [7] carbamide aniline nano-supermolecule conducting polymer, method for preparing same and use](https://images-eureka-patsnap-com.libproxy1.nus.edu.sg/patent_img/0bc37ada-ba6a-4a79-ac23-92e9813692e5/a20071015043500111.PNG "Calabash [7] carbamide aniline nano-supermolecule conducting polymer, method for preparing same and use")
![Calabash [7] carbamide aniline nano-supermolecule conducting polymer, method for preparing same and use](https://images-eureka-patsnap-com.libproxy1.nus.edu.sg/patent_img/0bc37ada-ba6a-4a79-ac23-92e9813692e5/a20071015043500112.PNG "Calabash [7] carbamide aniline nano-supermolecule conducting polymer, method for preparing same and use")
![Calabash [7] carbamide aniline nano-supermolecule conducting polymer, method for preparing same and use](https://images-eureka-patsnap-com.libproxy1.nus.edu.sg/patent_img/0bc37ada-ba6a-4a79-ac23-92e9813692e5/a20071015043500121.PNG "Calabash [7] carbamide aniline nano-supermolecule conducting polymer, method for preparing same and use")
Owner:NANKAI UNIV
Method for assembling and preparing novel organic solid fluorescent material by cucurbituril anions
The present invention discloses a method for assembling and preparing novel organic solid fluorescent material by cucurbituril anions, and belongs to the field of organic luminous materials. According to the method, macrocycle host compound cucurbituril is introduced into a specific organic fluorescent compound solution system; and by virtue of unique molecular recognition and assembly properties of the cucurbituril, the macrocycle host compound cucurbituril and a fluorescent functional compound form an anion assembly. The method can change a deposition mode of fluorescent molecules and perform effective controllable adjustment on fluorescent wavelength of the original fluorescence organic by the anion assembly, and even organic compounds that do not have the fluorescence property originally have the fluorescence property after being assembled with the cucurbituril anion. The method is simple in preparation method, and the obtained solid fluorescent material is high in yield rate and has the advantage of being capable of performing designing and modulating on a target fluorescence emission wavelength; and the method has a potential application value in various field such as color displays, anti-counterfeit marks, fluorescence sensors, molecular machines and the like.
Owner:DALIAN UNIV OF TECH
Stationary Phase and Column Using Cucurbituril Bonded Silica Gel, and Separation Method of Taxol Using the Column
InactiveUS20080290028A1Reduce purification costsHigh purityIon-exchange process apparatusOrganic chemistryStationary phaseSolvent
Provided are a stationary phase and a column using a cucurbituril-bound silica gel, and a method of separating taxane using the column. The taxane separation method includes: preparing a column for taxane separation, the column being packed with a stationary phase including a cucurbituril-bound silica gel in which a cucurbituril represented by Formula 1 or 2 is covalently bound to a modified silica gel represented by Formula 3; dissolving a taxane powder in a solvent to prepare a taxane-containing solution; applying the taxane-containing solution to the column; supplying a mobile-phase solvent to the column to obtain a taxane extract from the column; and purifying taxane from the taxane extract. Therefore, highly purified taxane can be separated from a low-purity crude taxane extract.
Owner:POSTECH ACAD IND FOUND
Method for preparing polymer containing cucurbituril structure
The invention discloses a method for preparing a polymer containing a cucurbituril structure. The method comprises the following steps of oxidizing cucurbituril by virtue of persulfate to obtain hydroxyl cucurbituril, further reacting hydroxyl cucurbituril to obtain polymerizable cucurbituril monomer and copolymerizing with other water-soluble monomers by virtue of free radical polymerization to obtain the polymer containing a cucurbituril structure. Since the cucurbituril unit is introduced into the middle side chain of the macromolecule, compared with the conventional polymer or the similar host molecule functionalized polymer, the polymer disclosed by the invention has the advantages of relatively strong binding capacity, better identification capability, relatively high chemical stability and good biocompatibility. The polymer has broad application prospects in the fields of medicine, biomaterials, cosmetic, analysis and the like.
Owner:SHANDONG UNIV
Supermolecule composite nanofiltration membrane and preparation method and application thereof
ActiveCN106731841AImprove hydrophilic abilityImprove hydrophilicityMembranesWater contaminantsCucurbiturilNonwoven fabric
The invention relates to a supermolecule composite nanofiltration membrane and preparation method and application thereof. The nanofiltration membrane mainly comprises a base layer and a modification layer on the base layer, wherein cucurbituril is distributed in the modifying layer. The preparation method comprises the following steps: preparing a base membrane solution; mechanically stirring until the base membrane is completely dissolved; standing to remove bubbles; scrapping on a nonwoven fabric to form a flat membrane; preparing aqueous solution of a first monomer and an organic solution of a second monomer; adding supermolecule to the first monomer aqueous solution, and stirring to dissolve; performing interfacial polymerization on the base membrane surface; and transferring the prepared membrane in deionized water to store for later use. The preparation method has the characteristics that the supermolecule is used as an interfacial polymerization, the preparation processes are simple; the prepared supermolecule composite nanofiltration membrane is high in flux and high in rejection rate.
Owner:南京蔚华膜科技有限公司
Introverted CB[N] Compounds
Inverted cucurbituril compounds having at least one pair of hydrogen atoms protruding into an internal molecular cavity thereof.
![Introverted CB[N] Compounds](https://images-eureka-patsnap-com.libproxy1.nus.edu.sg/patent_img/f61f9334-d609-49c4-a1fb-f4b3a67208cb/US20100010215A1-20100114-D00000.png "Introverted CB[N] Compounds")
![Introverted CB[N] Compounds](https://images-eureka-patsnap-com.libproxy1.nus.edu.sg/patent_img/f61f9334-d609-49c4-a1fb-f4b3a67208cb/US20100010215A1-20100114-D00001.png "Introverted CB[N] Compounds")
![Introverted CB[N] Compounds](https://images-eureka-patsnap-com.libproxy1.nus.edu.sg/patent_img/f61f9334-d609-49c4-a1fb-f4b3a67208cb/US20100010215A1-20100114-D00002.png "Introverted CB[N] Compounds")
Owner:UNIV OF MARYLAND +1
Supermolecular assembly for small interfering RNA targeting delivery and preparation method
InactiveCN104840975AAvoid decomposition and inactivationImprove gene transfection efficiencyGenetic material ingredientsPharmaceutical non-active ingredientsSide effectCancer cell
The invention relates to a supermolecular assembly for small interfering RNA targeting delivery. The supermolecular assembly is a four-element supermolecular assembly synthesized on the basis of beta-cyclodextrin modified hyaluronic acid, an adamantine polyamine compound, cucurbituril [6] and small interfering RNA. The four-element supermolecular assembly is based on the strong non-covalent interaction between beta-cyclodextrin and adamantine and between adamantine polyamine chain and cucurbituril [6], and the electrostatic interaction between the adamantine polyamine chain and small interfering RNA, and forms supermolecular nanoparticles with hydrophilic hyaluronic acid as the shell. The supermolecular assembly provided by the invention has the advantages of simple synthesis and construction route, low production cost and high yield, and is suitable for amplified synthesis and actual production application. Through the endocytosis of a malignant tumor cell surface overexpressed hyaluronic acid receptor as a medium, the four-element supermolecular assembly can be brought into cancer cells targetedly, thus realizing effective silencing to exogenous gene expression and significantly reducing the toxic and side effect at the same time.
Owner:NANKAI UNIV
Cucurbituril-containing polymer, stationary phase and column using the same
InactiveUS20060201862A1Ion-exchange process apparatusOrganic chemistryStationary phaseAir pollutants
Provided is a cucurbituril-containing polymer. The cucurbituril-containing polymer may be used in removal, separation, or purification of air pollutants, water contaminants, biological substances, organic or inorganic substances, alkaline metals, heavy metals, ionic or water-soluble biological substances. The cucurbituril-containing polymer may be a stationary phase that may be used for column chromatography.
Owner:POSTECH ACAD IND FOUND
Hexamethyl six-membered cucurbituril supramolecule self-assembled carrier and application thereof
ActiveCN108484562ASolid fluorescence enhancementThe preparation method is convenientOrganic chemistryLuminescent compositionsSelf assembleCucurbituril
The invention discloses a hexamethyl six-membered cucurbituril supramolecule self-assembled carrier and application thereof. The hexamethyl six-membered cucurbituril supramolecule self-assembled carrier is prepared from hexamethyl six-membered cucurbituril and a neutral aqueous solution which are used as raw materials. The carrier is of a multi-pore framework structure self-assembled on the basisof hexamethyl six-membered cucurbituril supramolecules. The structure can be used for preparing various solid fluorescent materials. The fluorescent material has a specific identification effect on specific volatile gas, and can be used for blending fluorescent materials in different colors, so that application of the hexamethyl six-membered cucurbituril is expanded. In addition, the fluorescent material of the invention has the characteristics of simple preparation process and low manufacturing cost.
Owner:GUIZHOU UNIV
A clathrate of an artemisinin type medicine and ring-opened cucurbituril and a preparation method thereof
InactiveCN108771675AImprove solubilityEasy to prepareOrganic active ingredientsPharmaceutical non-active ingredientsSolubilityMedicine
A clathrate of an artemisinin type medicine and ring-opened cucurbituril is provided. The clathrate contains the artemisinin type medicine and the ring-opened cucurbituril in a mole ratio of 2:1-8:1,and is prepared by a solvent inclusion process. A flexible molecule cavity of the ring-opened cucurbituril is utilized to match the artemisinin type medicine well, and good water solubility of the ring-opened cucurbituril is utilized to greatly improve water solubility of the artemisinin type medicine, thus facilitating formation of an artemisinin type medicine liquid preparation. The clathrate prepared by the preparation method has good water solubility and high stability. The preparation method is simple, mild in condition and easy to operate, and is applied for development of novel artemisinin type preparations. The clathrate has potential practical application value.
Owner:KUNMING UNIV OF SCI & TECH
Method and composition for removal of mercaptans from gas streams
A composition for removing mercaptan from a gas stream containing at least one acid gas in addition to a mercaptan, the composition comprising a physical and / or chemical solvent for H2S and an inclusion compound for the mercaptan. A process of treating gas stream using the composition. The inclusion compound is selected from the group consisting of, cyclodextrin, cryptand, calixarene. cucurbituril. The chemical solvent may be monoethanolamine (MEA), diethanolamine (DEA), triethanolamine (TEA, diisopropylamine (DIPA), diglycolamine (DGA) and methyldiethanolamine (MDEA). Examples of useful physical solvents include cyclotetramethylene sulfone (sulfolane) and its derivatives, aliphatic acid amides, NMP (n-methylpyrrolidone), N-alkylated pyrrolidones and corresponding piperidone methanol and mixtures of dialkethers of polyethylene glycols. The method copirses scrubbing preferably the natural gas with an aqueous solution comprising the above compounds followed by a stripping regeneration step.
Owner:DOW GLOBAL TECH LLC
Nested supramolecular capsules
A nested capsule having a first capsule held within a second capsule. Each of the first and second capsules has a shell that is a supramolecular cross-linked network, such as a cucurbituril supramolecular cross-linked network. Each capsule shell is obtained or is obtainable from the complexation of a composition including a host, such as cucurbituril, and one or more building blocks having suitable guest functionality for the host, thereby to form a supramolecular cross-linked network. The nested capsules are suitable for delivering and selectively releasing an encapsulant at a location.
Owner:CAMBRIDGE ENTERPRISE LTD
Heavy metal ion adsorbing material and preparation method thereof
InactiveCN108722365ASimple manufacturing methodRaw materials are easy to getWater/sewage treatment by irradiationOther chemical processesDesorptionCyclodextrin
The invention discloses a heavy metal ion adsorbing material. The heavy metal ion adsorbing material is prepared from the following components as raw materials in parts by weight: 50-60 parts of a cyclodextrin-based cucurbituril-based triazine copolymer, 20-30 parts of hyperbranched polyethyleneimine and 5-10 parts of graphene oxide. A preparation method of the heavy metal ion adsorbing material comprises the following steps: adding all the raw materials into a screw extruder according to the weight ratio, and blending and performing extrusion molding at 230 DEG C to 250 DEG C to obtain the heavy metal ion adsorbing material. The heavy metal ion adsorbing material disclosed by the invention has the advantages of low cost, good adsorption effect on heavy metal ions, high adsorption capacityand easy desorption.
Owner:上海甘投中铸科技有限公司
Supramolecular capsules
Provided is a capsule having a shell of material that is a supramolecular cross-linked network. The network is formed from a host-guest complexation of cucurbituril (the host) and one or more building blocks comprising suitable guest functionality. The complex non-covalently crosslinks the building block and / or non-covalently links the building block to another building block thereby forming the supramolecular cross-linked network. The capsules are obtained or obtainable by the complexation of a composition comprising cucurbituril and one or more building blocks having suitable cucurbituril guest functionality thereby to form a supramolecular cross-linked network.
Owner:CAMBRIDGE ENTERPRISE LTD
Biosensor for detecting peptidylarginine deiminases, and preparation method and application thereof
InactiveCN107271511AEasy to distinguishIncreased sensitivityMaterial analysis by electric/magnetic meansHl 60 cellCucurbituril
The invention relates to a biosensor for detecting peptidylarginine deiminases, and a preparation method and application thereof. The sensor is characterized in that a polypeptide chain 1 (FGGGRGAC) is modified on the surface of a gold electrode; the sulfydryl of the cysteine at the end C of the polypeptide chain fixes the polypeptide chain 1 onto the surface of the electrode through a gold-sulfur bond; polypeptide chain 2 (FGGGGGC) functional silver nanometer particles are connected with silver nanometer particles through the sulfydryl of cysteine of the polypeptide chain 2. Under the assistance of the mutual action of supermolecule cucurbituril 8(CB[8]) assisted subject and object, the functional silver nanometer particles can be recognized with FGG at the end N of the polypeptide chain 1 and FGG at the end N of the polypeptide chain 2 due to CB[B]. The biosensor uses a super molecular chemistry assistance signal marking method for improving the experiment sensitivity; the linear range of the PAD4 can be detected to be 0.005 nM to 200 nM; the detection limit is 0.79 nM; the specificity is very high; the target and other reference protein can be effectively distinguished; the goal of detecting the activity of the endogenous PAD4 in the HL-60 lysates can be achieved.
Owner:SHANGHAI UNIV
Method and composition for removal of mercaptans from gas streams
Owner:DOW GLOBAL TECH LLC
Alkali-sensitive ring opening cucurbituril and application thereof
ActiveCN108084194AGood alkali sensitivityReduced ring stiffnessOrganic active ingredientsOrganic chemistrySolubilityIrritation
The invention discloses alkali-sensitive ring opening cucurbituril. A structural formula of the alkali-sensitive ring opening cucurbituril is shown. The alkali-sensitive ring opening cucurbituril hasthe advantages that the alkali-sensitive ring opening cucurbituril can be used as a supermolecular medicine carrier and is provided with large ring cryptand with inner cavities, the ring rigidity of large rings can be reduced by means of ring opening, and accordingly the alkali-sensitive ring opening cucurbituril is extremely high in host-guest bonding capacity; the alkali-sensitive ring opening cucurbituril is excellent in alkali sensitivity, contains carboxylic acid groups and can be used as the medicine carrier to be widely applied to medicine delivery paths, and the water solubility and the stability of insoluble medicines can be greatly improved; the alkali-sensitive ring opening cucurbituril can be used as an alkali-sensitive carrier, medicines can be released in alkaline environments such as small intestines in human bodies, accordingly, effects of releasing the medicines in a sustained and controlled manner can be realized, and irritation of the medicines on gastric mucosas canbe prevented.
Owner:KUNMING UNIV OF SCI & TECH
Supermolecular compound, preparation method thereof, and method used for distinguishing microorganisms
ActiveCN106947089AImprove treatment efficiencyDelay drug resistanceMicrobiological testing/measurementBiotechnologyMicroorganism
The invention belongs to the field of supermolecular compound, and discloses a supermolecular compound, a preparation method thereof, and a method used for distinguishing microorganisms. The supermolecular compound possesses an inclusion complex structure composed of a conjugated polymer with a structure represented by formula (I), and cucurbituril [7], wherein R1 is used for representing one of structures represented by formula (II), formula (III), or formula (IV), n is used for representing an integer ranging from 30 to 300, R2, R3, and R4 are independently used for representing C1-C5 alkyl, Y is used for representing an alkylene with 6 to 12 carbon atoms, or one group with a general structure of -R5-O-R6- or -OR7-, R5, R6, and R7 are used for representing alkylenes, the carbon atom number of R7 ranges from 6 to 12, and X is used for representing a halogen. The method is high in speed, efficiency, and accuracy, and is convenient in distinguishing microorganisms such as bacteria, fungus, and virus.
Owner:INST OF CHEM CHINESE ACAD OF SCI
Preparation method and application of inclusion complexes of 1-methylcyclopropene and derivatives thereof
InactiveCN102273504AEasy to prepareWide variety of sourcesDead plant preservationFruit and vegetables preservationPreservative1-Methylcyclopropene
The invention relates to the technical field of preparation of plant fresh-keeping agents, and provides a preparation method and application of inclusions of 1-methylcyclopropene and derivatives thereof. The inclusion agent for preparing the inclusion compound of the present invention is a cucurbituril mixture or any single component thereof. The 1-methylcyclopropene and its derivatives can exist stably after forming an inclusion complex with cucurbituril, thereby providing a convenient method for storing and transporting these compounds that can inhibit ethylene reaction of plants. At the same time, the preparation process of the inclusion complex is simple, the cost is low, and it is convenient to use. When in use, only need to put the inclusion complex directly into water or an aqueous solution containing acid or alkali to re-release 1-methylcyclopropene and its derivatives. thing.
Owner:HUAZHONG AGRI UNIV
Frictionless molecular rotary motors
A rotaxane consisting of a cucurbituril and an uncharged guest molecule, having low or null affinity therebetween is provided as well as processes for providing the same. Various uses as energy converters (“frictionless” molecular motors), biochips and biosensors using the same are also provided.
Owner:TECHNION RES & DEV FOUND LTD
Liposome And Method Of Preparing The Same
Provided are a liposome formed by self-assembling a cucurbituril derivative and a method of preparing the liposome.
Owner:POSTECH ACAD IND FOUND
Method for preparing cucurbituril and cucurbituril derivative
Owner:DALIAN UNIV OF TECH
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