119results about How to "Stimulation" patented technology

An exemplary steerable stylet handle assembly includes a housing having first and second side walls defining a channel therebetween, a button in communication with the first and second side walls and configured to move distally and proximally within the channel, and a stylet subassembly having an inner stylet wire located at least partially within an outer tubing. The inner stylet wire has a pre-curved portion and is coupled to a proximal portion of the housing. The outer tubing is coupled to the button. Movement of the button within the channel is configured to selectively expose and cover at least a portion of the pre-curved distal portion of the inner stylet wire with the outer tubing.

Apparatus and methods for stimulating tissue employing local current imbalance to facilitate more effective stimulation regimens.

Described herein are devices, systems and methods to enhance the magnetic perturbation of a neuronal (e.g., brain) target during Transcranial Magnetic Stimulation (TMS), thereby enhancing the induced current in the target. In general, these devices, systems and methods enhance the magnetic perturbation (dB / dt) of the target by mechanically moving a TMS electromagnet (e.g. coil) at a frequency of greater than 1 kHz.

Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

Apparatus is provided including an external device including, a mount, which is placed in front of an eye of a subject. A power source is coupled to the mount and emits energy toward the eye. An intraocular device is implanted entirely in the subject's eye, and includes a control unit, a plurality of stimulating electrodes, and an energy receiver, which receives the energy from the power source and generates a voltage drop in response thereto. A plurality of photosensors detect photons and generate a signal in response thereto. Driving circuitry is coupled to the energy receiver and to the photosensors, and drives the electrodes to apply electrical charges to a retina in response to the signals from the photosensors. The external device modulates the emitted energy, and the control unit demodulates the modulated energy to regulate an operation parameter of the intraocular device. Other embodiments are also described.

A female stimulation device and method for enhancing female sexual stimulation. The device includes a body having a tip portion, a flange, and an intermediate side wall portion. The intermediate side wall portion extending from the tip portion to the flange. The vacuum produced by the device when applied to a user can be controlled to enhance clitoral blood flow without causing clitoral injury.

The invention provides a method for preparing seaweed urea. Firstly, a concentrated seaweed extract is prepared; during the prilling process of urea, the concentrated seaweed extract and a fused urea solution are evenly mixed, wherein, the weight proportion of the concentrated seaweed extract and the urea added is 50 to 200:1000; then prilling is conducted in a prilling tower to prepare seaweed urea products. After the prilling of the concentrated seaweed extract and the fused urea, the concentrated seaweed extract exists in the form of solid seaweed extract, wherein, the weight percentage of the solid seaweed extract in the seaweed urea is 0.5 percent to 2 percent and the weight percentage of the urea is 98 percent to 99.5 percent. The combination of seaweed and urea can greatly improve the absorption and utilization ratio of urea, and meanwhile has the function of restraining the fast decomposition of urea contents and slowing down loss, thus effectively solving the problem of soil deterioration in current fertilization.

The invention discloses a compound composition used for increasing the crop fertilization rate. The compound composition comprises a first component of phethalanilic acid, a second component selected from one or more of brassinolide, 6-benayl aminopurine, compound sodium nitrophenolate, diethyl aminoethyl hexanoate, prohexadione calcium, grain yellowing agents, forchlorfenuron, triacontanol, chlormequat chloride, mepiquat chloride, paclobutrazol, uniconazole, amino-oligosaccharin, humic acid, amino acid, alginic acid and chitosan oligosaccharide, and a third component selected from one or more of boric fertilizer, calcium fertilizer, nitrogen fertilizer, potash fertilizer, phosphatic fertilizer, iron fertilizer, copper fertilizer, magnesium fertilizer, manganese fertilizer, molybdenum fertilizer and silicon fertilizer. The composition can be prepared into an aqueous solution or a soluble solution or wettable powder or water dispersible granules which are allowed to be used for agriculture. The compatibility of all the components is reasonable, the key risks of the phethalanilic acid are lowered while it is ensured that the crop fertilization rate is effectively increased, the nutrition level and stress-resistant capacity of crops are improved, and the increase of production and income of crops is promoted.

Subdural arrays transmit electrocorticogram recordings wirelessly, across the patient's skull, allowing the craniotomy used for surgical placement of the arrays to be completely closed. In various embodiments, the arrays also respond to commands, applying signal patterns to the patient's brain for diagnostic and treatment purposes.

The invention provides a synergistic compound fertilizer and a production method thereof. The production method comprises the following steps: firstly producing an alginic acid solution through an enzymatic hydrolysis method, mixing the alginic acid solution with inorganic raw materials according to a certain proportion, granulating through a high tower, and drying by a drum drying machine so as to get a finished product. The content of alginic acid in the product, namely a compound fertilizer synergist provided by the invention is 0.3%-20%, and the total content (calculated by N, P2O5 and K2O) of the inorganic nutrients is 25%-80%. The synergistic compound fertilizer provided by the method disclosed by the invention can significantly improve the quality of crops, is conductive to growth of root systems of the crops and has an important significance in the aspects of improving an ecological environment of farmland, easing the disproportionality of the fertilizer and the like.

The invention discloses an organosilicon quaternary ammonium long-acting antibacterial product and a preparation method of the organosilicon quaternary ammonium long-acting antibacterial product. The product comprises a first organosilicon quaternary ammonium antibacterial component, a second organosilicon quaternary ammonium antibacterial component and a third synergistic component, wherein the first organosilicon quaternary ammonium antibacterial component is dimethyl alkyl [3-(trimethoxysilyl) propyl] ammonium halide containing C10-C16 alkyl, and the halogen is preferably Cl (chlorine) and Br (bromine); the second organosilicon quaternary ammonium antibacterial component is dimethyl alkyl [3-(trimethoxysilyl) propyl] ammonium halide containing C18-C30 carbon chains, and the halogen is preferably F (fluorine), Cl (chlorine) and I (iodine); the third synergistic component is selected from a group comprising tea polyphenol, aloe and chitosan or a group comprising composition of polyphenol, aloe and chitosan. The antibacterial agent has broad-spectrum antibacterial performance, lasts long, is poisonless, has no irritation to the skin, is especially applicable to sensitive parts of the skin and is a good choice in daily life, wound treatment and operation assistance.

Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

The invention relates to application of collagen chelate in the preparation of medicament or food for enhancing bone quality. The medicament or food can enhance bone strength, can enhance bone strength and bone density at the same time and can be used for curing and / or preventing osteoporosis. The collagen chelate is a metalloprotein conjugate; compared with calcium carbonate (CaCO3) with the same calcium concentration, the collagen chelate can enhance the bone density by 4.4 percent and enhance the bone strength by 9.9 percent; and compared with a mixture of collagen and calcium carbonate (CaCO3) with the same concentration of collagen and calcium carbonate, the collagen chelate has a more obvious effect.

The invention relates to a high-performance high-density polyethylene (HDPE) pipe fitting which consists of functional master batches and an HDPE base material. A preparation method is characterized by comprising the following steps of: selecting raw materials, mixing the raw materials, feeding the raw materials under vacuum, drying the raw materials, extruding the raw materials by an inner layer extruder, extruding the raw materials by an outer layer extruder, fixing the diameter by a diameter fixing sleeve, spraying a vacuum sizing box, spraying a cooling water tank, spraying codes by a code sprayer, conveying a product by a caterpillar-tractor, packaging finished products, and detecting the specifications of the HDPE pipe fittings. The HDPE pipe fitting can be produced by using existing equipment and a production technology; the additional value of the products can be increased; the HDPE pipe fitting can be widely applied.

The invention discloses an activity-enhanced algae microorganism fertilizer and a preparation method thereof. The microorganism fertilizer breaks through the structure of a conventional fertilizer, algae fermentation liquor is taken as a synergistic ingredient, and microorganisms are added, and the microorganism fertilizer is finally processed in a scientific manner. The algae fermentation liquor not only can be used as a synergist to promote nutrient absorption of plants, but also can play roles of controlled release and coating on nutrients, provides a safer growth environment for crops, and promotes stable yield, high yield and high quality of the crops. Microbial flora can degrade nutrients in soil, promote crop absorption, and improve the soil structure.

The invention discloses an epididymis protease inhibitor which is a functional peptide segment of Eppin. The inhibitor is any one selected from amino acid sequences shown from SEQ ID No.1 to SEQ ID No.7 and has advantages of single component, simple structure and strong pertinence of immunoreaction inspired; polypeptide with at least 80 percent of sequences the same as the functional peptide segment of Eppin can be used for constructing immunogen which can improve the immunogenicity of the functional peptide segment of Eppin, stimulate an organism to generate a specific antibody, reduce Eppin level in blood plasma and induce high-efficient, safe and reversible antifertility effect. The immunogen of the epididymis protease inhibitor can form a medicament composite with medically acceptable carriers, and the composite can be used for preparing male contraception vaccines, therefore, the epididymis protease inhibitor has broad application prospect.

Disclosed herein are a pure silver device and a method for diagnosing and treating pain on human body. The pure silver device comprises an elongated handle, a head having both a hammer head and a comb opposed to each other, a panel, and an outwardly extending protrusion on the bottom end of the handle. The pure silver device is used to diagnose and treat pain by finding out pressure pain points on both abdominal area, at which root of pain is located, and a symptomatic area of the human body and then by releasing the pressure pain points by tapping, pressing, rubbing, combing or combining the foregoing. Owing to the highest thermal and electrical conductivity of silver, the pure silver device produces amazingly better stimulation of the pressure pain points. Therefore, the pure silver device is more effectively used for diagnosing and treating pain than other devices made out of any other material, even sterling silver and magnetic material. In addition, the pure silver device is portable and useful in that anyone can diagnose and treat himself or herself anytime and anyplace. The pure silver device and the method are simple, easy, safe without any side effects and medical risks, and economical.

Devices, systems, and methods for neuromodulation are provided. For example, a neuromodulation system is disclosed that comprises an implantable neuromodulation module having a photodiode configured to generate electrical current in response to receiving light from an optical fiber; an optical transceiver; and at least one electrode configured to provide electrical stimulation to a nerve utilizing the electrical current generated by the photodiode. As another example, a method of neuromodulation is disclosed that comprises receiving light at a photodiode of a neuromodulation module and generating electrical current in response to receiving the light; and providing, via at least one electrode of the module positioned within the patient, electrical stimulation to a nerve of the patient utilizing the electrical current generated by the photodiode.

The invention discloses a foot and mouth disease virus-like particle vaccine and a preparation method thereof. By expressing P12A (three amino acid site mutation, VP1K210E, VP1E83K and VP1C134S) and serum-free suspension culture, a virus-like particle (VLP) standard similar to natural 75S FMDV is built, and VLP yield is increased. The invention further provides serum-free suspension cultured and high pH tamed insect cells, the insect cells can stably and efficiently produce FMDV VLP, the size and structure of the VLP produced by the insect cells is similar to those of the VLP produced by standard BHK-21, and the yield of the VLP produced by the insect cells is 11 times of that of the VLP produced by female parent cells Sf21. The vaccine prepared by the VLP produced by the insect cells can immunize animals to generate IgG antibody response. The IgG antibody titer, foot and mouth disease virus neutralizing antibody titer and antibody titer of immunization of the VLP vaccine produced by the insect cells are not evidently different from those of immunization of the VLP vaccine prepared by the BHK-21, so that the high-pH-adaptive insect cells are applicable to FMDV VLP vaccine production.

The invention provides a salicylic acid solubilizing slow-release composition. The salicylic acid solubilizing slow-release composition is prepared from a specific proportion of active ingredient salicylic acid, solubilizing slow-release agent poloxamer 407, a humectant, a skin feeling conditioning agent, a preservative system and deionized water. The salicylic acid solubilizing slow-release composition has the advantages that under the conditions without alcohol and at a low pH value, the salicylic acid is prepared into a stable, easy-to-use and low-irritant water-soluble liquid, gel, or an intermediate state between the water-soluble liquid and the gel; on one hand, the solubility of the salicylic acid in an aqueous phase can be significantly improved, thereby increasing the biological utilization rate of the salicylic acid, on the other hand, the irritation of the salicylic acid to the skin can be significantly reduced, thereby solving the technical problem of the high-concentrationsalicylic acid intolerance of wide crowds. In addition, the invention further relates to a preparation method and application of the salicylic acid solubilizing slow-release composition.

The invention discloses Chinese wampee fruit-haw apple fruit wine and a preparation method thereof. The preparation method comprises the following steps: cleaning and denucleating fresh Chinese wampee fruits and haw apples, pulping the fruits through a beating machine, putting the pulp in a fermentation tank, pouring powdery crystal sugar into the fermentation tank according to a proportion, performing pasteuring at 70 DEG C, adding activation yeast to carry out anaerobic fermentation, wherein the fermentation tank is a cask, a colored glass jar or a ceramic pot, the fermentation temperature is 20-30 DEG C, and the fermentation time is controlled within 8-20 days to finish complete fermentation; and then, detecting, filtering and filling to obtain a product, wherein the alcoholic strength is 10-12 degrees. The Chinese wampee fruit-haw apple fruit wine disclosed by the invention is a kind of healthy beverage having the functions of improving digestion, regulating qi-flowing for strengthening spleen, promoting qi circulation to relieve pain, engendering liquid and quenching thirst, and no preservative, additive, essence, pigment or monosodium glutamate is added.

A fitted garment that covers specific muscle areas in the back area of the body. It is a spandex / cotton material with strategically placed pockets sewn into specific areas of the material. Inside these pockets, high-density foam therapeutic balls are placed to facilitate in massaging specific muscles in the back area of the body.The garment fits securely to the upper body, and is secured by closing fitted straps and plastic buckles in the front area of the body. Because the garment is secured on the body, the person wearing it can move freely and with the use of their own body, they can apply pressure to the muscles by leaning against an object that would allow the balls to put pressure on these specific muscles. This process releases tension from the muscle and increases blood flow and range of motion. Because there are ten (10) pockets in specific areas of the garment, the same muscles are always being massaged allowing better relief and healthy blood flow to these muscles. The garment allows for the user to choose if they would like to use all the therapeutic balls at the same time or use only a few to massage certain muscles at certain times. The balls are interchangeable, allowing for this flexibility in use. Only high-density foam balls are used in this product, the pockets are sized to hold them in place for a greater therapeutic effect.

The invention discloses a recombinant porcine circovirus type 2 (PCV2) virus-like particle (VLP). The VLP is prepared by connecting a protein transduction domain originated from HSV-1VP22 with an antigen Cap gene needed for formation of PCV2 hollow capsid protein by using an SOE-PCR method, then carrying out cloning to a baculovirus transporter so as to obtain a homologous recombinant vector, carrying out encapsulation so as to produce recombinant baculovirus containing PCV2Cap protein and the protein transduction domain of HSV-1VP22, infecting an insect cell and expressing recombinant Cap-VP22 protein in which PCV2Cap protein and the protein transduction domain of HSV-1VP22 are fused. According to results of research, the VLP prepared in the invention can be individually used or used with adjuvant for inoculation to an animal and effectively stimulates generation of a specific antibody to PCV2. Thus, the VLP provided by the invention can be applied to development of a novel high-efficiency PCV2 subunit vaccine with a good immune effect.

The invention provides a special clinical nutritional formula for gynecological inflammation. The special clinical nutritional formula comprises the following components in parts by weight: 14-30 parts of protein, 1-10 parts of fat, 45-65 parts of carbohydrates, 5-10 parts of dietary fibers, 0.5-1.5 parts of major elements, 0.008-0.05 part of trace elements, 0.008-0.02 part of fat-soluble vitamins, 0.09-0.28 part of water-soluble vitamins, 0.05-2 parts of dietary essence, 0.5-3 parts of medicinal and edible components and 0.005-2 parts of new resource food. The invention also provides a preparation method of the nutritional formula. The special clinical nutritional formula is capable of improving the body functions of patients, strengthening nutrients, improving body immunity to avoid repeated attack of gynecological inflammation and simultaneously relieving the symptoms of gynecological inflammation.

The invention provides an additive-free anti-aging cosmetic and a preparation method thereof. The cosmetic is prepared from the following components in percentage by weight: a component A: 0.01-0.2 percent of sodium hyaluronate, 2-10 percent of 1,3-butanediol, 3-5 percent of 1,2-pentanediol and 70-90 percent of water; a component B: 0.3-1.0 percent of a mixture of 1,2-hexanediol and 1,2-ethohexadiol; a component C: 0.5-5 percent of collagen; a component D: 0.01-0.2 percent of carnosine; and a component E: 0.05-0.3 percent of natural essence. Every 100 percent of the additive-free anti-aging cosmetic comprises 0.3-1 percent of component B, 0.5-5 percent of component C, 0.01-0.5 percent of component D, 0.05-0.5 percent of component E and the balance of component A.